JP2024513087A5 - - Google Patents
Info
- Publication number
- JP2024513087A5 JP2024513087A5 JP2023561238A JP2023561238A JP2024513087A5 JP 2024513087 A5 JP2024513087 A5 JP 2024513087A5 JP 2023561238 A JP2023561238 A JP 2023561238A JP 2023561238 A JP2023561238 A JP 2023561238A JP 2024513087 A5 JP2024513087 A5 JP 2024513087A5
- Authority
- JP
- Japan
- Prior art keywords
- dna
- polynucleotide
- cas
- composition according
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163171651P | 2021-04-07 | 2021-04-07 | |
| US63/171,651 | 2021-04-07 | ||
| US202163292144P | 2021-12-21 | 2021-12-21 | |
| US63/292,144 | 2021-12-21 | ||
| PCT/EP2022/059070 WO2022214522A2 (en) | 2021-04-07 | 2022-04-06 | Compositions and methods for site-specific modification |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024513087A JP2024513087A (ja) | 2024-03-21 |
| JP2024513087A5 true JP2024513087A5 (https=) | 2025-04-15 |
Family
ID=81603442
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023561238A Pending JP2024513087A (ja) | 2021-04-07 | 2022-04-06 | 部位特異的改変のための組成物及び方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20240182890A1 (https=) |
| EP (1) | EP4320234A2 (https=) |
| JP (1) | JP2024513087A (https=) |
| WO (1) | WO2022214522A2 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4133069A2 (en) * | 2020-04-08 | 2023-02-15 | Astrazeneca AB | Compositions and methods for improved site-specific modification |
| CN121002177A (zh) * | 2023-03-10 | 2025-11-21 | 先正达农作物保护股份公司 | 用于位点特异性整合的cas融合蛋白和相关方法 |
| WO2025035110A1 (en) * | 2023-08-10 | 2025-02-13 | Linearx, Inc. | Compositions and methods for in vitro transcription |
| WO2026083309A1 (en) | 2024-10-17 | 2026-04-23 | Astrazeneca Ab | Use of inhibitors or modulators of artemis in gene editing |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5543158A (en) | 1993-07-23 | 1996-08-06 | Massachusetts Institute Of Technology | Biodegradable injectable nanoparticles |
| US6007845A (en) | 1994-07-22 | 1999-12-28 | Massachusetts Institute Of Technology | Nanoparticles and microparticles of non-linear hydrophilic-hydrophobic multiblock copolymers |
| US5855913A (en) | 1997-01-16 | 1999-01-05 | Massachusetts Instite Of Technology | Particles incorporating surfactants for pulmonary drug delivery |
| US5895309A (en) | 1998-02-09 | 1999-04-20 | Spector; Donald | Collapsible hula-hoop |
| SE0201863D0 (en) | 2002-06-18 | 2002-06-18 | Cepep Ab | Cell penetrating peptides |
| JP2008078613A (ja) | 2006-08-24 | 2008-04-03 | Rohm Co Ltd | 窒化物半導体の製造方法及び窒化物半導体素子 |
| EP3269395A1 (en) | 2008-11-07 | 2018-01-17 | Massachusetts Institute Of Technology | Aminoalcohol lipidoids and uses thereof |
| US9193827B2 (en) | 2010-08-26 | 2015-11-24 | Massachusetts Institute Of Technology | Poly(beta-amino alcohols), their preparation, and uses thereof |
| EP2691443B1 (en) | 2011-03-28 | 2021-02-17 | Massachusetts Institute of Technology | Conjugated lipomers and uses thereof |
| AU2013266968B2 (en) | 2012-05-25 | 2017-06-29 | Emmanuelle CHARPENTIER | Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription |
| US8697359B1 (en) | 2012-12-12 | 2014-04-15 | The Broad Institute, Inc. | CRISPR-Cas systems and methods for altering expression of gene products |
| DK2931891T3 (da) | 2012-12-17 | 2019-08-19 | Harvard College | Rna-styret modificering af menneskelige genomer |
| CA2910802A1 (en) | 2013-04-12 | 2014-10-16 | Samir El Andaloussi | Therapeutic delivery vesicles |
| US9650617B2 (en) | 2015-01-28 | 2017-05-16 | Pioneer Hi-Bred International. Inc. | CRISPR hybrid DNA/RNA polynucleotides and methods of use |
| US9790490B2 (en) | 2015-06-18 | 2017-10-17 | The Broad Institute Inc. | CRISPR enzymes and systems |
| EP3443088B1 (en) * | 2016-04-13 | 2024-09-18 | Editas Medicine, Inc. | Grna fusion molecules, gene editing systems, and methods of use thereof |
| GB201609216D0 (en) | 2016-05-25 | 2016-07-06 | Evox Therapeutics And Isis Innovation Ltd | Exosomes comprising therapeutic polypeptides |
| WO2018094356A2 (en) * | 2016-11-18 | 2018-05-24 | Genedit Inc. | Compositions and methods for target nucleic acid modification |
| CA3052099A1 (en) * | 2017-01-30 | 2018-08-02 | Mathias LABS | Repair template linkage to endonucleases for genome engineering |
| EP3679143A1 (en) * | 2017-09-08 | 2020-07-15 | Life Technologies Corporation | Methods for improved homologous recombination and compositions thereof |
| US11649442B2 (en) * | 2017-09-08 | 2023-05-16 | The Regents Of The University Of California | RNA-guided endonuclease fusion polypeptides and methods of use thereof |
| CN120310773A (zh) | 2017-11-16 | 2025-07-15 | 阿斯利康(瑞典)有限公司 | 用于改善基于Cas9的敲入策略的有效性的组合物和方法 |
| EP3781677A4 (en) * | 2018-04-16 | 2022-01-19 | University of Massachusetts | COMPOSITIONS AND METHODS FOR IMPROVED GENE EDITTING |
| CN113825834A (zh) * | 2019-03-11 | 2021-12-21 | 索伦托药业有限公司 | 使用rna引导的核酸内切酶进行dna构建体整合的改进工艺 |
| WO2020191233A1 (en) * | 2019-03-19 | 2020-09-24 | The Broad Institute, Inc. | Methods and compositions for editing nucleotide sequences |
| WO2021034373A1 (en) * | 2019-08-19 | 2021-02-25 | Minghong Zhong | Conjugates of guide rna-cas protein complex |
| US20210079387A1 (en) * | 2019-08-27 | 2021-03-18 | The Jackson Laboratory | Cleavage-resistant donor nucleic acids and methods of use |
-
2022
- 2022-04-06 WO PCT/EP2022/059070 patent/WO2022214522A2/en not_active Ceased
- 2022-04-06 JP JP2023561238A patent/JP2024513087A/ja active Pending
- 2022-04-06 EP EP22722690.9A patent/EP4320234A2/en active Pending
- 2022-04-06 US US18/554,014 patent/US20240182890A1/en active Pending
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