JP2010535031A5 - - Google Patents
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- JP2010535031A5 JP2010535031A5 JP2010519925A JP2010519925A JP2010535031A5 JP 2010535031 A5 JP2010535031 A5 JP 2010535031A5 JP 2010519925 A JP2010519925 A JP 2010519925A JP 2010519925 A JP2010519925 A JP 2010519925A JP 2010535031 A5 JP2010535031 A5 JP 2010535031A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- target
- reaction mixture
- target sequence
- double
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000000034 method Methods 0.000 claims 26
- 239000011541 reaction mixture Substances 0.000 claims 11
- 238000002844 melting Methods 0.000 claims 3
- 150000007523 nucleic acids Chemical group 0.000 claims 3
- 238000012217 deletion Methods 0.000 claims 2
- 230000037430 deletion Effects 0.000 claims 2
- 238000003780 insertion Methods 0.000 claims 2
- 230000037431 insertion Effects 0.000 claims 2
- 230000008018 melting Effects 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 238000003753 real-time PCR Methods 0.000 claims 2
- 238000012163 sequencing technique Methods 0.000 claims 2
- 108700028369 Alleles Proteins 0.000 claims 1
- 101000829171 Hypocrea virens (strain Gv29-8 / FGSC 10586) Effector TSP1 Proteins 0.000 claims 1
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 1
- DWAQJAXMDSEUJJ-UHFFFAOYSA-M Sodium bisulfite Chemical compound [Na+].OS([O-])=O DWAQJAXMDSEUJJ-UHFFFAOYSA-M 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- 238000004925 denaturation Methods 0.000 claims 1
- 230000036425 denaturation Effects 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 238000007847 digital PCR Methods 0.000 claims 1
- 238000001840 matrix-assisted laser desorption--ionisation time-of-flight mass spectrometry Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 238000012175 pyrosequencing Methods 0.000 claims 1
- 238000007894 restriction fragment length polymorphism technique Methods 0.000 claims 1
- 239000000523 sample Substances 0.000 claims 1
- 235000010267 sodium hydrogen sulphite Nutrition 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96283807P | 2007-08-01 | 2007-08-01 | |
| US60/962,838 | 2007-08-01 | ||
| PCT/US2008/009248 WO2009017784A2 (en) | 2007-08-01 | 2008-07-31 | Enrichment of a target sequence |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010535031A JP2010535031A (ja) | 2010-11-18 |
| JP2010535031A5 true JP2010535031A5 (enExample) | 2013-08-08 |
| JP5531367B2 JP5531367B2 (ja) | 2014-06-25 |
Family
ID=40305136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010519925A Expired - Fee Related JP5531367B2 (ja) | 2007-08-01 | 2008-07-31 | 標的配列の濃縮 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8455190B2 (enExample) |
| EP (1) | EP2183379B1 (enExample) |
| JP (1) | JP5531367B2 (enExample) |
| KR (1) | KR101376359B1 (enExample) |
| CN (1) | CN101815789B (enExample) |
| AU (1) | AU2008282780B2 (enExample) |
| CA (1) | CA2695264C (enExample) |
| DK (1) | DK2183379T3 (enExample) |
| ES (1) | ES2547053T3 (enExample) |
| PT (1) | PT2183379E (enExample) |
| WO (1) | WO2009017784A2 (enExample) |
Families Citing this family (72)
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| US11111544B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
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| US8980561B1 (en) | 2006-08-22 | 2015-03-17 | Los Alamos National Security, Llc. | Nucleic acid detection system and method for detecting influenza |
| EP2574681B1 (en) | 2007-03-28 | 2016-03-23 | Signal Diagnostics | System and method for high resolution analysis of nucleic acids to detect sequence variations |
| ES2547053T3 (es) | 2007-08-01 | 2015-10-01 | Dana Farber Cancer Institute | Enriquecimiento de una secuencia diana |
| CA2723536C (en) | 2008-05-05 | 2017-06-13 | Los Alamos National Security, Llc | Highly simplified lateral flow-based nucleic acid sample preparation and passive fluid flow control |
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| US11332793B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for simultaneous amplification of target loci |
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| US20190010543A1 (en) | 2010-05-18 | 2019-01-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
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| US10316362B2 (en) | 2010-05-18 | 2019-06-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US12221653B2 (en) | 2010-05-18 | 2025-02-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11326208B2 (en) | 2010-05-18 | 2022-05-10 | Natera, Inc. | Methods for nested PCR amplification of cell-free DNA |
| US11408031B2 (en) | 2010-05-18 | 2022-08-09 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
| US12152275B2 (en) | 2010-05-18 | 2024-11-26 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
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| US11939634B2 (en) | 2010-05-18 | 2024-03-26 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| JP6153874B2 (ja) | 2011-02-09 | 2017-06-28 | ナテラ， インコーポレイテッド | 非侵襲的出生前倍数性呼び出しのための方法 |
| US20120225421A1 (en) * | 2011-02-28 | 2012-09-06 | Transgenomic, Inc. | Kit and method for sequencing a target dna in a mixed population |
| ITTO20110271A1 (it) | 2011-03-28 | 2012-09-29 | Fabio Gentilini | Metodo per l'identificazione di polimorfismi genetici di base singola. |
| DK2691541T3 (en) * | 2011-03-31 | 2018-01-22 | Dana Farber Cancer Inst Inc | PROCEDURE FOR ENRICHMENT OF SINGLE DRAWED MUTANTS SEQUENCES FROM A MIXTURE OF WILD TYPE AND MUTANTS |
| KR101878889B1 (ko) | 2011-04-20 | 2018-07-16 | 메사 바이오테크, 인크. | 핵산의 왕복 증폭 반응 |
| WO2012151328A2 (en) | 2011-05-02 | 2012-11-08 | President And Fellows Of Harvard College | Spatial sequestration of dynamic nucleic acid circuits |
| WO2013009736A2 (en) | 2011-07-10 | 2013-01-17 | President And Fellows Of Harvard College | Compositions and methods for self-assembly of polymers with complementary macroscopic and microscopic scale units |
| WO2013010074A1 (en) | 2011-07-13 | 2013-01-17 | Primeradx, Inc. | Multimodal methods for simultaneous detection and quantification of multiple nucleic acids in a sample |
| US9074247B2 (en) * | 2011-10-06 | 2015-07-07 | Drexel University | P53 assay for a urine test for HCC screening |
| JP6420148B2 (ja) | 2011-10-14 | 2018-11-07 | ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ | 矩形波サーマルサイクリング |
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| US10706957B2 (en) | 2012-09-20 | 2020-07-07 | The Chinese University Of Hong Kong | Non-invasive determination of methylome of tumor from plasma |
| US9732390B2 (en) | 2012-09-20 | 2017-08-15 | The Chinese University Of Hong Kong | Non-invasive determination of methylome of fetus or tumor from plasma |
| US10913977B2 (en) | 2013-07-24 | 2021-02-09 | Dana-Farber Cancer Institute, Inc. | Methods and compositions to enable enrichment of minor DNA alleles by limiting denaturation time in PCR or simply enable enrichment of minor DNA alleles by limiting the denaturation time in PCR |
| CN105793435A (zh) | 2013-10-09 | 2016-07-20 | 弗洛雷森特里克公司 | 多重探针 |
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| JP2016535987A (ja) * | 2013-10-20 | 2016-11-24 | トローバジーン インコーポレイテッド | 核酸配列の合成及び濃縮 |
| CN103602748A (zh) * | 2013-11-28 | 2014-02-26 | 瑞希基因科技（北京）股份有限公司 | 一种结合荧光定量pcr技术的焦磷酸测序方法 |
| US12492429B2 (en) | 2014-04-21 | 2025-12-09 | Natera, Inc. | Detecting mutations and ploidy in chromosomal segments |
| JP6659575B2 (ja) | 2014-04-21 | 2020-03-04 | ナテラ， インコーポレイテッド | 変異の検出および染色体分節の倍数性 |
| US20180173846A1 (en) | 2014-06-05 | 2018-06-21 | Natera, Inc. | Systems and Methods for Detection of Aneuploidy |
| WO2016008451A1 (en) | 2014-07-18 | 2016-01-21 | The Chinese University Of Hong Kong | Methylation pattern analysis of tissues in dna mixture |
| SG10202005427PA (en) | 2015-04-24 | 2020-07-29 | Mesa Biotech Inc | Fluidic test cassette |
| DK3294906T3 (en) | 2015-05-11 | 2024-08-05 | Natera Inc | Methods for determining ploidy |
| RS60032B1 (sr) * | 2015-05-18 | 2020-04-30 | Saga Diagnostics Ab | Detekcija ciljne nukleinske kiseline i varijanti |
| EP4435112A3 (en) * | 2015-05-27 | 2025-02-26 | Quest Diagnostics Investments Incorporated | Compositions and methods for screening solid tumors |
| WO2017070339A1 (en) * | 2015-10-20 | 2017-04-27 | Richardson Katherine | Microfluidic device for enrichment of nucleic acid sequence alterations |
| CN109477138A (zh) | 2016-04-15 | 2019-03-15 | 纳特拉公司 | 肺癌检测方法 |
| WO2018067517A1 (en) | 2016-10-04 | 2018-04-12 | Natera, Inc. | Methods for characterizing copy number variation using proximity-litigation sequencing |
| GB201618485D0 (en) | 2016-11-02 | 2016-12-14 | Ucl Business Plc | Method of detecting tumour recurrence |
| AU2017369018B2 (en) | 2016-11-30 | 2021-02-25 | The Chinese University Of Hong Kong | Analysis of cell-free DNA in urine and other samples |
| US10011870B2 (en) | 2016-12-07 | 2018-07-03 | Natera, Inc. | Compositions and methods for identifying nucleic acid molecules |
| EP3551756A4 (en) | 2016-12-12 | 2020-07-15 | Dana Farber Cancer Institute, Inc. | COMPOSITIONS AND METHODS FOR MOLECULAR BARCODE CODING OF DNA MOLECULES BEFORE ENRICHMENT OF MUTATIONS AND / OR DETECTION OF MUTATIONS |
| US11174511B2 (en) | 2017-07-24 | 2021-11-16 | Dana-Farber Cancer Institute, Inc. | Methods and compositions for selecting and amplifying DNA targets in a single reaction mixture |
| WO2019099420A1 (en) * | 2017-11-15 | 2019-05-23 | Yan Wang | A method for detecting multiple dna mutations and copy number variations |
| US12084720B2 (en) | 2017-12-14 | 2024-09-10 | Natera, Inc. | Assessing graft suitability for transplantation |
| CN119753091A (zh) | 2018-04-02 | 2025-04-04 | 格里尔公司 | 用于扩增与癌症相关联的cfDNA分子的化验板 |
| CN112236535A (zh) | 2018-04-14 | 2021-01-15 | 纳特拉公司 | 用于借助于循环肿瘤dna的个人化检测的癌症检测和监测的方法 |
| US12234509B2 (en) | 2018-07-03 | 2025-02-25 | Natera, Inc. | Methods for detection of donor-derived cell-free DNA |
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| JP6544783B1 (ja) | 2018-07-31 | 2019-07-17 | 学校法人 岩手医科大学 | がんの診断のためのプローブ／プライマーライブラリー |
| EP3856903A4 (en) | 2018-09-27 | 2022-07-27 | Grail, LLC | METHYLATION MARKER AND TARGETED METHYLATION PROBE PANEL |
| EP3980559A1 (en) | 2019-06-06 | 2022-04-13 | Natera, Inc. | Methods for detecting immune cell dna and monitoring immune system |
| US20220290209A1 (en) | 2019-08-21 | 2022-09-15 | Dana-Farber Cancer Institute, Inc. | Multi-site enrichment of deletions in dna microsatellites |
| US11866793B2 (en) | 2020-03-27 | 2024-01-09 | Regents Of The University Of Minnesota | Assay for detecting palmer amaranth DNA in individual and mixed samples |
| JPWO2024111057A1 (enExample) | 2022-11-22 | 2024-05-30 |
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-
2008
- 2008-07-31 ES ES08794916.0T patent/ES2547053T3/es active Active
- 2008-07-31 PT PT87949160T patent/PT2183379E/pt unknown
- 2008-07-31 CN CN2008801098230A patent/CN101815789B/zh active Active
- 2008-07-31 US US12/671,295 patent/US8455190B2/en not_active Expired - Fee Related
- 2008-07-31 KR KR1020107004305A patent/KR101376359B1/ko active Active
- 2008-07-31 WO PCT/US2008/009248 patent/WO2009017784A2/en not_active Ceased
- 2008-07-31 CA CA2695264A patent/CA2695264C/en not_active Expired - Fee Related
- 2008-07-31 EP EP08794916.0A patent/EP2183379B1/en active Active
- 2008-07-31 AU AU2008282780A patent/AU2008282780B2/en not_active Ceased
- 2008-07-31 JP JP2010519925A patent/JP5531367B2/ja not_active Expired - Fee Related
- 2008-07-31 DK DK08794916.0T patent/DK2183379T3/en active
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