PT2183379E - Enriquecimento de uma sequência alvo - Google Patents
Enriquecimento de uma sequência alvo Download PDFInfo
- Publication number
- PT2183379E PT2183379E PT87949160T PT08794916T PT2183379E PT 2183379 E PT2183379 E PT 2183379E PT 87949160 T PT87949160 T PT 87949160T PT 08794916 T PT08794916 T PT 08794916T PT 2183379 E PT2183379 E PT 2183379E
- Authority
- PT
- Portugal
- Prior art keywords
- enrichment
- target sequence
- sequence
- target
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96283807P | 2007-08-01 | 2007-08-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2183379E true PT2183379E (pt) | 2015-09-25 |
Family
ID=40305136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT87949160T PT2183379E (pt) | 2007-08-01 | 2008-07-31 | Enriquecimento de uma sequência alvo |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8455190B2 (enExample) |
| EP (1) | EP2183379B1 (enExample) |
| JP (1) | JP5531367B2 (enExample) |
| KR (1) | KR101376359B1 (enExample) |
| CN (1) | CN101815789B (enExample) |
| AU (1) | AU2008282780B2 (enExample) |
| CA (1) | CA2695264C (enExample) |
| DK (1) | DK2183379T3 (enExample) |
| ES (1) | ES2547053T3 (enExample) |
| PT (1) | PT2183379E (enExample) |
| WO (1) | WO2009017784A2 (enExample) |
Families Citing this family (72)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9424392B2 (en) | 2005-11-26 | 2016-08-23 | Natera, Inc. | System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals |
| US11111544B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| WO2008105814A2 (en) | 2006-08-22 | 2008-09-04 | Los Alamos National Security, Llc | Miniturized lateral flow device for rapid and sensitive detection of proteins or nucleic acids |
| US8980561B1 (en) | 2006-08-22 | 2015-03-17 | Los Alamos National Security, Llc. | Nucleic acid detection system and method for detecting influenza |
| CN101903535A (zh) | 2007-03-28 | 2010-12-01 | 信号诊断公司 | 高解析度分析核酸以检测序列变异的系统和方法 |
| KR101376359B1 (ko) | 2007-08-01 | 2014-03-27 | 다나-파버 캔서 인스티튜트 인크. | 표적 서열 강화 |
| EP2279403B1 (en) | 2008-05-05 | 2016-03-16 | Los Alamos National Security, LLC | Highly simplified lateral flow-based nucleic acid sample preparation and passive fluid flow control |
| US10669574B2 (en) | 2008-11-18 | 2020-06-02 | XCR Diagnostics, Inc. | DNA amplification technology |
| JP5795341B2 (ja) * | 2010-03-08 | 2015-10-14 | デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド | 参照ブロック配列によるｆｕｌｌＣＯＬＤ−ＰＣＲ濃縮 |
| KR101312241B1 (ko) * | 2010-04-27 | 2013-09-27 | 사회복지법인 삼성생명공익재단 | 증폭억제시발체를 이용하는 유전자 돌연변이 검출 방법 |
| US11339429B2 (en) | 2010-05-18 | 2022-05-24 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11408031B2 (en) | 2010-05-18 | 2022-08-09 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
| US11322224B2 (en) | 2010-05-18 | 2022-05-03 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US20190010543A1 (en) | 2010-05-18 | 2019-01-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US10316362B2 (en) | 2010-05-18 | 2019-06-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11332793B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US12152275B2 (en) | 2010-05-18 | 2024-11-26 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11332785B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US9677118B2 (en) | 2014-04-21 | 2017-06-13 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11939634B2 (en) | 2010-05-18 | 2024-03-26 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US8825412B2 (en) | 2010-05-18 | 2014-09-02 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11326208B2 (en) | 2010-05-18 | 2022-05-10 | Natera, Inc. | Methods for nested PCR amplification of cell-free DNA |
| US12221653B2 (en) | 2010-05-18 | 2025-02-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| CA2824387C (en) | 2011-02-09 | 2019-09-24 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| KR20140010093A (ko) * | 2011-02-28 | 2014-01-23 | 트랜스제노믹, 인크. | 혼합 집단 중 표적 dna의 서열분석을 위한 키트 및 방법 |
| ITTO20110271A1 (it) | 2011-03-28 | 2012-09-29 | Fabio Gentilini | Metodo per l'identificazione di polimorfismi genetici di base singola. |
| EP2691541B1 (en) * | 2011-03-31 | 2017-10-18 | Dana-Farber Cancer Institute, Inc. | Method for enriching in single-stranded mutant sequences from mixture of wild-type and mutant sequences |
| ES2583135T3 (es) | 2011-04-20 | 2016-09-19 | Mesa Biotech, Inc. | Dispositivo integrado para la detección e identificación de ácidos nucleicos |
| WO2012151328A2 (en) | 2011-05-02 | 2012-11-08 | President And Fellows Of Harvard College | Spatial sequestration of dynamic nucleic acid circuits |
| US9617392B2 (en) | 2011-07-10 | 2017-04-11 | President And Fellows Of Harvard College | Compositions and methods for self-assembly of polymers with complementary macroscopic and microscopic scale units |
| EP2744916A4 (en) | 2011-07-13 | 2015-06-17 | Primeradx Inc | MULTIMODAL PROCEDURE FOR THE SIMULTANEOUS DETECTION AND QUANTIFICATION OF MULTIPLE NUCLEIC ACIDS IN ONE SAMPLE |
| US9074247B2 (en) * | 2011-10-06 | 2015-07-07 | Drexel University | P53 assay for a urine test for HCC screening |
| CN103998921B (zh) | 2011-10-14 | 2016-04-20 | 贝克顿·迪金森公司 | 方波热循环 |
| US9133490B2 (en) | 2012-05-16 | 2015-09-15 | Transgenomic, Inc. | Step-up method for COLD-PCR enrichment |
| CN104350161A (zh) * | 2012-06-14 | 2015-02-11 | 弗莱德哈钦森癌症研究中心 | 用于核酸分子中的敏感突变检测的组合物和方法 |
| US20140100126A1 (en) | 2012-08-17 | 2014-04-10 | Natera, Inc. | Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data |
| US9732390B2 (en) | 2012-09-20 | 2017-08-15 | The Chinese University Of Hong Kong | Non-invasive determination of methylome of fetus or tumor from plasma |
| US10706957B2 (en) | 2012-09-20 | 2020-07-07 | The Chinese University Of Hong Kong | Non-invasive determination of methylome of tumor from plasma |
| WO2015013166A1 (en) * | 2013-07-24 | 2015-01-29 | Dana-Farber Cancer Institute, Inc. | Methods and compositions to enable enrichment of minor dna alleles by limiting denaturation time in pcr or simply enable enrichment of minor dna alleles by limiting denaturation time in pcr |
| ES2925313T3 (es) | 2013-10-09 | 2022-10-14 | Fluoresentric Inc | Método para la detección de secuencias de ácido nucleico diana |
| US20160273022A1 (en) * | 2013-10-20 | 2016-09-22 | Trovagene, Inc. | Synthesis and enrichment of nucleic acid sequences |
| CA2922261A1 (en) * | 2013-10-20 | 2015-05-21 | Trovagene, Inc. | Synthesis and enrichment of nucleic acid sequences |
| CN103602748A (zh) * | 2013-11-28 | 2014-02-26 | 瑞希基因科技（北京）股份有限公司 | 一种结合荧光定量pcr技术的焦磷酸测序方法 |
| EP3957749A1 (en) | 2014-04-21 | 2022-02-23 | Natera, Inc. | Detecting tumour specific mutations in biopsies with whole exome sequencing and in cell-free samples |
| US12492429B2 (en) | 2014-04-21 | 2025-12-09 | Natera, Inc. | Detecting mutations and ploidy in chromosomal segments |
| US20180173846A1 (en) | 2014-06-05 | 2018-06-21 | Natera, Inc. | Systems and Methods for Detection of Aneuploidy |
| KR102295290B1 (ko) * | 2014-07-10 | 2021-08-30 | 플루어레센트릭 인코포레이티드 | Dna 증폭 기술 |
| TWI895765B (zh) | 2014-07-18 | 2025-09-01 | 香港中文大學 | Dna混合物中之組織甲基化模式分析 |
| WO2016172724A1 (en) | 2015-04-24 | 2016-10-27 | Mesa Biotech, Inc. | Fluidic test cassette |
| US11479812B2 (en) | 2015-05-11 | 2022-10-25 | Natera, Inc. | Methods and compositions for determining ploidy |
| HUE048349T2 (hu) * | 2015-05-18 | 2020-07-28 | Saga Diagnostics Ab | Célnukleinsavak és variánsok detektálása |
| WO2016190897A1 (en) * | 2015-05-27 | 2016-12-01 | Quest Diagnostics Investments Incorporated | Compositions and methods for screening solid tumors |
| WO2017070339A1 (en) * | 2015-10-20 | 2017-04-27 | Richardson Katherine | Microfluidic device for enrichment of nucleic acid sequence alterations |
| JP7280044B2 (ja) | 2016-04-15 | 2023-05-23 | ナテラ， インコーポレイテッド | 肺癌の検出方法 |
| WO2018067517A1 (en) | 2016-10-04 | 2018-04-12 | Natera, Inc. | Methods for characterizing copy number variation using proximity-litigation sequencing |
| GB201618485D0 (en) | 2016-11-02 | 2016-12-14 | Ucl Business Plc | Method of detecting tumour recurrence |
| IL315032A (en) | 2016-11-30 | 2024-10-01 | Univ Hong Kong Chinese | Analysis of cell-free dna in urine and other samples |
| US10011870B2 (en) | 2016-12-07 | 2018-07-03 | Natera, Inc. | Compositions and methods for identifying nucleic acid molecules |
| CA3046953A1 (en) | 2016-12-12 | 2018-06-21 | Dana Farber Cancer Institute, Inc. | Compositions and methods for molecular barcoding of dna molecules prior to mutation enrichment and/or mutation detection |
| WO2019023243A1 (en) | 2017-07-24 | 2019-01-31 | Dana-Farber Cancer Institute, Inc. | METHODS AND COMPOSITIONS FOR SELECTING AND AMPLIFYING DNA TARGETS IN A SINGLE REACTION MIXTURE |
| WO2019099420A1 (en) * | 2017-11-15 | 2019-05-23 | Yan Wang | A method for detecting multiple dna mutations and copy number variations |
| WO2019118926A1 (en) | 2017-12-14 | 2019-06-20 | Tai Diagnostics, Inc. | Assessing graft suitability for transplantation |
| DE202019005627U1 (de) | 2018-04-02 | 2021-05-31 | Grail, Inc. | Methylierungsmarker und gezielte Methylierungssondenpanels |
| US12024738B2 (en) | 2018-04-14 | 2024-07-02 | Natera, Inc. | Methods for cancer detection and monitoring |
| US12234509B2 (en) | 2018-07-03 | 2025-02-25 | Natera, Inc. | Methods for detection of donor-derived cell-free DNA |
| GB201812192D0 (en) | 2018-07-26 | 2018-09-12 | Ttp Plc | Variable temperature reactor, heater and control circuit for the same |
| JP6544783B1 (ja) | 2018-07-31 | 2019-07-17 | 学校法人 岩手医科大学 | がんの診断のためのプローブ／プライマーライブラリー |
| AU2019351130B2 (en) | 2018-09-27 | 2025-10-23 | GRAIL, Inc | Methylation markers and targeted methylation probe panel |
| WO2020247263A1 (en) | 2019-06-06 | 2020-12-10 | Natera, Inc. | Methods for detecting immune cell dna and monitoring immune system |
| EP4017998B1 (en) | 2019-08-21 | 2024-11-06 | Dana-Farber Cancer Institute, Inc. | Multi-site enrichment of deletions in dna microsatellites |
| US11866793B2 (en) | 2020-03-27 | 2024-01-09 | Regents Of The University Of Minnesota | Assay for detecting palmer amaranth DNA in individual and mixed samples |
| EP4624573A1 (en) | 2022-11-22 | 2025-10-01 | Quantdetect, Inc. | Probe/primer library for cancer diagnosis |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4458066A (en) | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| US5310652A (en) | 1986-08-22 | 1994-05-10 | Hoffman-La Roche Inc. | Reverse transcription with thermostable DNA polymerase-high temperature reverse transcription |
| CA1340807C (en) | 1988-02-24 | 1999-11-02 | Lawrence T. Malek | Nucleic acid amplification process |
| GB2228086A (en) | 1988-11-25 | 1990-08-15 | Ici Plc | Characterisation of genomic DNA |
| KR920700360A (ko) | 1989-03-22 | 1992-02-19 | 하리크 프리드리히 | 미끄럼 베어링 |
| US5075217A (en) | 1989-04-21 | 1991-12-24 | Marshfield Clinic | Length polymorphisms in (dC-dA)n ·(dG-dT)n sequences |
| AU5645690A (en) | 1989-05-05 | 1990-11-29 | Lifecodes Corporation | Method for genetic analysis of a nucleic acid sample |
| CA2020958C (en) | 1989-07-11 | 2005-01-11 | Daniel L. Kacian | Nucleic acid sequence amplification methods |
| US5045450A (en) * | 1989-07-13 | 1991-09-03 | Massachusetts Institute Of Technology | Determination of a mutational spectrum |
| DE3938907C2 (de) | 1989-11-24 | 1999-11-04 | Dade Behring Marburg Gmbh | Mittel zum Lagern und Suspendieren von Zellen, insbesondere Erythrozyten |
| US5427930A (en) | 1990-01-26 | 1995-06-27 | Abbott Laboratories | Amplification of target nucleic acids using gap filling ligase chain reaction |
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| EP0516753A4 (en) | 1990-02-26 | 1994-05-18 | Us Health | A method for the fluorescent detection of a dna sequence in real time |
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| JP3785517B2 (ja) | 1997-06-05 | 2006-06-14 | 東ソー株式会社 | 核酸融解温度測定法 |
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-
2008
- 2008-07-31 KR KR1020107004305A patent/KR101376359B1/ko not_active Expired - Fee Related
- 2008-07-31 EP EP08794916.0A patent/EP2183379B1/en active Active
- 2008-07-31 WO PCT/US2008/009248 patent/WO2009017784A2/en not_active Ceased
- 2008-07-31 AU AU2008282780A patent/AU2008282780B2/en not_active Ceased
- 2008-07-31 JP JP2010519925A patent/JP5531367B2/ja not_active Expired - Fee Related
- 2008-07-31 US US12/671,295 patent/US8455190B2/en not_active Expired - Fee Related
- 2008-07-31 CA CA2695264A patent/CA2695264C/en not_active Expired - Fee Related
- 2008-07-31 PT PT87949160T patent/PT2183379E/pt unknown
- 2008-07-31 DK DK08794916.0T patent/DK2183379T3/en active
- 2008-07-31 CN CN2008801098230A patent/CN101815789B/zh active Active
- 2008-07-31 ES ES08794916.0T patent/ES2547053T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2183379A2 (en) | 2010-05-12 |
| DK2183379T3 (en) | 2015-07-27 |
| CN101815789B (zh) | 2013-06-12 |
| ES2547053T3 (es) | 2015-10-01 |
| EP2183379B1 (en) | 2015-04-15 |
| AU2008282780B2 (en) | 2014-04-17 |
| CN101815789A (zh) | 2010-08-25 |
| KR20100044870A (ko) | 2010-04-30 |
| CA2695264A1 (en) | 2009-02-05 |
| CA2695264C (en) | 2015-01-27 |
| JP2010535031A (ja) | 2010-11-18 |
| AU2008282780A1 (en) | 2009-02-05 |
| WO2009017784A3 (en) | 2009-03-26 |
| JP5531367B2 (ja) | 2014-06-25 |
| US20100203532A1 (en) | 2010-08-12 |
| EP2183379A4 (en) | 2011-08-10 |
| WO2009017784A2 (en) | 2009-02-05 |
| US8455190B2 (en) | 2013-06-04 |
| KR101376359B1 (ko) | 2014-03-27 |
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| PL2112455T3 (pl) | Urządzenie rozruchowe | |
| GB2470421B (en) | Training cartridge | |
| GB0609979D0 (en) | Target | |
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| EP2274447A4 (en) | NEW DIVERGENT PICORNAVIRUS: COSAVIRUS | |
| GB0801764D0 (en) | A gun case | |
| ZA200900827B (en) | Miniature detonator | |
| GB0719982D0 (en) | Bombs | |
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| GB0601059D0 (en) | Target | |
| GB2448785B (en) | Improved dart |