JP2010533707A5 - - Google Patents
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- Publication number
- JP2010533707A5 JP2010533707A5 JP2010516705A JP2010516705A JP2010533707A5 JP 2010533707 A5 JP2010533707 A5 JP 2010533707A5 JP 2010516705 A JP2010516705 A JP 2010516705A JP 2010516705 A JP2010516705 A JP 2010516705A JP 2010533707 A5 JP2010533707 A5 JP 2010533707A5
- Authority
- JP
- Japan
- Prior art keywords
- deoxy
- branched
- linear
- prostaglandin compound
- fatty acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 20
- 235000014113 dietary fatty acids Nutrition 0.000 claims 13
- 239000000194 fatty acid Substances 0.000 claims 13
- 229930195729 fatty acid Natural products 0.000 claims 13
- -1 fatty acid ester Chemical class 0.000 claims 11
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical group N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 8
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims 8
- 125000000217 alkyl group Chemical group 0.000 claims 8
- 125000004423 acyloxy group Chemical group 0.000 claims 6
- 150000001338 aliphatic hydrocarbons Chemical class 0.000 claims 6
- 125000003118 aryl group Chemical group 0.000 claims 6
- 125000004432 carbon atom Chemical group C* 0.000 claims 6
- 229910052736 halogen Inorganic materials 0.000 claims 6
- 150000002367 halogens Chemical class 0.000 claims 6
- 125000000623 heterocyclic group Chemical group 0.000 claims 6
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 6
- 125000004043 oxo group Chemical group O=* 0.000 claims 6
- 125000005456 glyceride group Chemical group 0.000 claims 5
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 claims 4
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 4
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 4
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 4
- 125000003545 alkoxy group Chemical group 0.000 claims 4
- 125000004104 aryloxy group Chemical group 0.000 claims 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 4
- 229910052799 carbon Inorganic materials 0.000 claims 4
- 150000001721 carbon Chemical group 0.000 claims 4
- 150000004665 fatty acids Chemical class 0.000 claims 4
- 229910052757 nitrogen Inorganic materials 0.000 claims 4
- 229910052760 oxygen Inorganic materials 0.000 claims 4
- 239000001301 oxygen Substances 0.000 claims 4
- 229920006395 saturated elastomer Polymers 0.000 claims 4
- 239000011593 sulfur Chemical group 0.000 claims 4
- 229910052717 sulfur Chemical group 0.000 claims 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 3
- 150000002148 esters Chemical class 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 150000001298 alcohols Chemical class 0.000 claims 2
- 125000001931 aliphatic group Chemical group 0.000 claims 2
- 150000001408 amides Chemical class 0.000 claims 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 235000011187 glycerol Nutrition 0.000 claims 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 2
- 239000001257 hydrogen Substances 0.000 claims 2
- 150000002431 hydrogen Chemical class 0.000 claims 2
- 125000004356 hydroxy functional group Chemical group O* 0.000 claims 2
- 125000001820 oxy group Chemical group [*:1]O[*:2] 0.000 claims 2
- 238000002360 preparation method Methods 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 239000002775 capsule Substances 0.000 claims 1
- XUGNVMKQXJXZCD-UHFFFAOYSA-N isopropyl palmitate Chemical group CCCCCCCCCCCCCCCC(=O)OC(C)C XUGNVMKQXJXZCD-UHFFFAOYSA-N 0.000 claims 1
- 239000002480 mineral oil Substances 0.000 claims 1
- 235000010446 mineral oil Nutrition 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92994807P | 2007-07-19 | 2007-07-19 | |
| US60/929,948 | 2007-07-19 | ||
| PCT/JP2008/063222 WO2009011449A2 (en) | 2007-07-19 | 2008-07-16 | Pharmaceutical composition comprising 11-deoxy-prostaglandin compound and method for stabilizing the compound |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013211759A Division JP2014001247A (ja) | 2007-07-19 | 2013-10-09 | １１−デオキシ−プロスタグランジン化合物を含む医薬組成物およびその安定化方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010533707A JP2010533707A (ja) | 2010-10-28 |
| JP2010533707A5 true JP2010533707A5 (enExample) | 2013-05-09 |
| JP5390519B2 JP5390519B2 (ja) | 2014-01-15 |
Family
ID=39720491
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010516705A Expired - Fee Related JP5390519B2 (ja) | 2007-07-19 | 2008-07-16 | １１−デオキシ−プロスタグランジン化合物を含む医薬組成物およびその安定化方法 |
| JP2013211759A Pending JP2014001247A (ja) | 2007-07-19 | 2013-10-09 | １１−デオキシ−プロスタグランジン化合物を含む医薬組成物およびその安定化方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013211759A Pending JP2014001247A (ja) | 2007-07-19 | 2013-10-09 | １１−デオキシ−プロスタグランジン化合物を含む医薬組成物およびその安定化方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US8969324B2 (enExample) |
| EP (2) | EP2327398A3 (enExample) |
| JP (2) | JP5390519B2 (enExample) |
| KR (1) | KR101485212B1 (enExample) |
| CN (2) | CN101808623B (enExample) |
| AU (1) | AU2008276840B2 (enExample) |
| BR (1) | BRPI0814115B8 (enExample) |
| CA (1) | CA2691995C (enExample) |
| IL (1) | IL203064B (enExample) |
| MX (1) | MX339727B (enExample) |
| NZ (2) | NZ595270A (enExample) |
| RU (3) | RU2506072C2 (enExample) |
| TW (2) | TWI446912B (enExample) |
| WO (1) | WO2009011449A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101410097A (zh) * | 2006-01-24 | 2009-04-15 | 株式会社·R-技术上野 | 软明胶胶囊制剂 |
| CN107903173A (zh) * | 2011-08-05 | 2018-04-13 | 苏坎波公司 | 治疗精神分裂症的方法 |
| WO2014159679A1 (en) | 2013-03-12 | 2014-10-02 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Methods for using lubiprostone to absorb fluid from the subretinal space |
| JP6580414B2 (ja) * | 2015-08-07 | 2019-09-25 | 小林製薬株式会社 | 生薬末含有錠剤 |
| US10716544B2 (en) | 2015-10-08 | 2020-07-21 | Zmk Medical Technologies Inc. | System for 3D multi-parametric ultrasound imaging |
| CN108619107A (zh) * | 2018-05-28 | 2018-10-09 | 青海制药厂有限公司 | 一种含鲁比前列酮的软胶囊及其制备方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE572839A (enExample) * | 1958-02-12 | |||
| JPS5350141A (en) * | 1976-10-18 | 1978-05-08 | Ono Pharmaceut Co Ltd | Stabilization of prostaglandin and prostaglandin analogues |
| US4310543A (en) | 1980-10-09 | 1982-01-12 | Hoffmann-La Roche Inc. | Prostaglandin compositions |
| US4301175A (en) * | 1980-12-29 | 1981-11-17 | The Upjohn Company | E-Type prostaglandin compositions |
| US4431833A (en) * | 1982-12-27 | 1984-02-14 | American Cyanamid Company | Prostaglandin and hydroxylated fatty acid ester formulations |
| KR920007569B1 (ko) * | 1984-11-30 | 1992-09-07 | 쥬우가이 세이야꾸 가부시끼가이샤 | 프로스타글란딘 e 유도체의 안정한 제제의 제조방법 |
| US5166174A (en) * | 1987-01-28 | 1992-11-24 | K.K. Ueno Seiyaku Oyo Kenkyujo | Prostaglandins E and anti-ulcers containing same |
| US6183466B1 (en) * | 1998-08-21 | 2001-02-06 | Alza Corporation | Dosage form comprising a capsule |
| EP1220849B1 (en) * | 1999-10-15 | 2004-05-19 | Sucampo AG | Bicyclic compounds composition and method for stabilizing the same |
| ATE387191T1 (de) * | 2002-04-25 | 2008-03-15 | Banner Pharmacaps Inc | Kaubare weichkapsel |
| FR2850275B1 (fr) * | 2003-01-24 | 2005-04-08 | Scherer Technologies Inc R P | Capsules molles a macher contenant une substance active a gout masque |
| DE602004015507D1 (de) * | 2004-02-17 | 2008-09-11 | Symrise Gmbh & Co Kg | Überzogene, sphärische, nahtlose, gefüllte kapseln |
| BRPI0607084A2 (pt) * | 2005-01-27 | 2009-08-04 | Sucampo Ag | uso de um composto 11-desóxiprostaglandina, composição compreendendo o mesmo, e composto |
| TWI432201B (zh) | 2005-03-04 | 2014-04-01 | Sucampo Ag | 11-去氧基-前列腺素化合物用於治療週邊血管疾病之用途 |
| CN101410097A (zh) | 2006-01-24 | 2009-04-15 | 株式会社·R-技术上野 | 软明胶胶囊制剂 |
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2008
- 2008-07-16 JP JP2010516705A patent/JP5390519B2/ja not_active Expired - Fee Related
- 2008-07-16 CN CN2008800250368A patent/CN101808623B/zh not_active Expired - Fee Related
- 2008-07-16 MX MX2010000693A patent/MX339727B/es active IP Right Grant
- 2008-07-16 CA CA2691995A patent/CA2691995C/en active Active
- 2008-07-16 AU AU2008276840A patent/AU2008276840B2/en not_active Ceased
- 2008-07-16 NZ NZ59527008A patent/NZ595270A/xx not_active IP Right Cessation
- 2008-07-16 WO PCT/JP2008/063222 patent/WO2009011449A2/en not_active Ceased
- 2008-07-16 NZ NZ583203A patent/NZ583203A/en not_active IP Right Cessation
- 2008-07-16 EP EP20110158821 patent/EP2327398A3/en not_active Withdrawn
- 2008-07-16 BR BRPI0814115A patent/BRPI0814115B8/pt active IP Right Grant
- 2008-07-16 CN CN2013102926965A patent/CN103393618A/zh active Pending
- 2008-07-16 US US12/174,230 patent/US8969324B2/en active Active
- 2008-07-16 KR KR1020107003612A patent/KR101485212B1/ko not_active Expired - Fee Related
- 2008-07-16 EP EP08778342.9A patent/EP2178516B1/en not_active Not-in-force
- 2008-07-16 RU RU2010105847/15A patent/RU2506072C2/ru active
- 2008-07-17 TW TW97127090A patent/TWI446912B/zh not_active IP Right Cessation
- 2008-07-17 TW TW103122235A patent/TWI552772B/zh not_active IP Right Cessation
-
2009
- 2009-12-31 IL IL203064A patent/IL203064B/en active IP Right Grant
-
2013
- 2013-07-26 RU RU2013135403A patent/RU2651471C2/ru active
- 2013-10-09 JP JP2013211759A patent/JP2014001247A/ja active Pending
-
2015
- 2015-01-06 US US14/590,067 patent/US9254326B2/en not_active Expired - Fee Related
-
2018
- 2018-04-12 RU RU2018113296A patent/RU2018113296A/ru not_active Application Discontinuation