RU2506072C2 - Фармацевтическая композиция, содержащая 11-дезокси-простагландиновое соединение, и способ стабилизации этого соединения - Google Patents

Фармацевтическая композиция, содержащая 11-дезокси-простагландиновое соединение, и способ стабилизации этого соединения Download PDF

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Publication number
RU2506072C2
RU2506072C2 RU2010105847/15A RU2010105847A RU2506072C2 RU 2506072 C2 RU2506072 C2 RU 2506072C2 RU 2010105847/15 A RU2010105847/15 A RU 2010105847/15A RU 2010105847 A RU2010105847 A RU 2010105847A RU 2506072 C2 RU2506072 C2 RU 2506072C2
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Russia
Prior art keywords
deoxy
prostaglandin compound
compound
soft gelatin
alkyl
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RU2010105847/15A
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English (en)
Russian (ru)
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RU2010105847A (ru
Inventor
Ясухиро ХАРАДА
Дзюнити КАВАСАКИ
Ёсие НИСИМУРА
Риюдзи УЕНО
Original Assignee
Р-Тек Уено, Лтд.
Сукампо Аг
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Publication of RU2010105847A publication Critical patent/RU2010105847A/ru
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
RU2010105847/15A 2007-07-19 2008-07-16 Фармацевтическая композиция, содержащая 11-дезокси-простагландиновое соединение, и способ стабилизации этого соединения RU2506072C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92994807P 2007-07-19 2007-07-19
US60/929,948 2007-07-19
PCT/JP2008/063222 WO2009011449A2 (en) 2007-07-19 2008-07-16 Pharmaceutical composition comprising 11-deoxy-prostaglandin compound and method for stabilizing the compound

Related Child Applications (1)

Application Number Title Priority Date Filing Date
RU2013135403A Division RU2651471C2 (ru) 2007-07-19 2013-07-26 Фармацевтическая композиция, содержащая 11-дезокси-простагландиновое соединение, и способ стабилизации этого соединения

Publications (2)

Publication Number Publication Date
RU2010105847A RU2010105847A (ru) 2011-08-27
RU2506072C2 true RU2506072C2 (ru) 2014-02-10

Family

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Family Applications (3)

Application Number Title Priority Date Filing Date
RU2010105847/15A RU2506072C2 (ru) 2007-07-19 2008-07-16 Фармацевтическая композиция, содержащая 11-дезокси-простагландиновое соединение, и способ стабилизации этого соединения
RU2013135403A RU2651471C2 (ru) 2007-07-19 2013-07-26 Фармацевтическая композиция, содержащая 11-дезокси-простагландиновое соединение, и способ стабилизации этого соединения
RU2018113296A RU2018113296A (ru) 2007-07-19 2018-04-12 Фармацевтическая композиция, содержащая 11-дезокси-простагландиновое соединение и способ стабилизации этого соединения

Family Applications After (2)

Application Number Title Priority Date Filing Date
RU2013135403A RU2651471C2 (ru) 2007-07-19 2013-07-26 Фармацевтическая композиция, содержащая 11-дезокси-простагландиновое соединение, и способ стабилизации этого соединения
RU2018113296A RU2018113296A (ru) 2007-07-19 2018-04-12 Фармацевтическая композиция, содержащая 11-дезокси-простагландиновое соединение и способ стабилизации этого соединения

Country Status (14)

Country Link
US (2) US8969324B2 (enExample)
EP (2) EP2327398A3 (enExample)
JP (2) JP5390519B2 (enExample)
KR (1) KR101485212B1 (enExample)
CN (2) CN101808623B (enExample)
AU (1) AU2008276840B2 (enExample)
BR (1) BRPI0814115B8 (enExample)
CA (1) CA2691995C (enExample)
IL (1) IL203064B (enExample)
MX (1) MX339727B (enExample)
NZ (2) NZ595270A (enExample)
RU (3) RU2506072C2 (enExample)
TW (2) TWI446912B (enExample)
WO (1) WO2009011449A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101410097A (zh) * 2006-01-24 2009-04-15 株式会社·R-技术上野 软明胶胶囊制剂
CN107903173A (zh) * 2011-08-05 2018-04-13 苏坎波公司 治疗精神分裂症的方法
WO2014159679A1 (en) 2013-03-12 2014-10-02 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods for using lubiprostone to absorb fluid from the subretinal space
JP6580414B2 (ja) * 2015-08-07 2019-09-25 小林製薬株式会社 生薬末含有錠剤
US10716544B2 (en) 2015-10-08 2020-07-21 Zmk Medical Technologies Inc. System for 3D multi-parametric ultrasound imaging
CN108619107A (zh) * 2018-05-28 2018-10-09 青海制药厂有限公司 一种含鲁比前列酮的软胶囊及其制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4310543A (en) * 1980-10-09 1982-01-12 Hoffmann-La Roche Inc. Prostaglandin compositions
US4431833A (en) * 1982-12-27 1984-02-14 American Cyanamid Company Prostaglandin and hydroxylated fatty acid ester formulations
WO2006080549A2 (en) * 2005-01-27 2006-08-03 Sucampo Ag Method and composition for treating central nervous system disorders

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BE572839A (enExample) * 1958-02-12
JPS5350141A (en) * 1976-10-18 1978-05-08 Ono Pharmaceut Co Ltd Stabilization of prostaglandin and prostaglandin analogues
US4301175A (en) * 1980-12-29 1981-11-17 The Upjohn Company E-Type prostaglandin compositions
KR920007569B1 (ko) * 1984-11-30 1992-09-07 쥬우가이 세이야꾸 가부시끼가이샤 프로스타글란딘 e 유도체의 안정한 제제의 제조방법
US5166174A (en) * 1987-01-28 1992-11-24 K.K. Ueno Seiyaku Oyo Kenkyujo Prostaglandins E and anti-ulcers containing same
US6183466B1 (en) * 1998-08-21 2001-02-06 Alza Corporation Dosage form comprising a capsule
EP1220849B1 (en) * 1999-10-15 2004-05-19 Sucampo AG Bicyclic compounds composition and method for stabilizing the same
ATE387191T1 (de) * 2002-04-25 2008-03-15 Banner Pharmacaps Inc Kaubare weichkapsel
FR2850275B1 (fr) * 2003-01-24 2005-04-08 Scherer Technologies Inc R P Capsules molles a macher contenant une substance active a gout masque
DE602004015507D1 (de) * 2004-02-17 2008-09-11 Symrise Gmbh & Co Kg Überzogene, sphärische, nahtlose, gefüllte kapseln
TWI432201B (zh) 2005-03-04 2014-04-01 Sucampo Ag 11-去氧基-前列腺素化合物用於治療週邊血管疾病之用途
CN101410097A (zh) 2006-01-24 2009-04-15 株式会社·R-技术上野 软明胶胶囊制剂

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4310543A (en) * 1980-10-09 1982-01-12 Hoffmann-La Roche Inc. Prostaglandin compositions
US4431833A (en) * 1982-12-27 1984-02-14 American Cyanamid Company Prostaglandin and hydroxylated fatty acid ester formulations
WO2006080549A2 (en) * 2005-01-27 2006-08-03 Sucampo Ag Method and composition for treating central nervous system disorders

Non-Patent Citations (1)

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Title
ЧУЕШОВ В.И. и др. Промышленная технология лекарств. в 2 томах. - Харьков: Издательство НФАУ МТК-Книга. - 2002, т.2, с.396. *

Also Published As

Publication number Publication date
NZ583203A (en) 2011-10-28
WO2009011449A3 (en) 2010-04-29
MX339727B (es) 2016-06-06
CN101808623A (zh) 2010-08-18
WO2009011449A2 (en) 2009-01-22
RU2013135403A (ru) 2015-02-10
TWI552772B (zh) 2016-10-11
BRPI0814115A2 (pt) 2015-02-03
RU2651471C2 (ru) 2018-04-19
AU2008276840A1 (en) 2009-01-22
CN101808623B (zh) 2013-08-14
CA2691995C (en) 2016-04-26
JP5390519B2 (ja) 2014-01-15
EP2178516B1 (en) 2015-09-09
CN103393618A (zh) 2013-11-20
CA2691995A1 (en) 2009-01-22
US20150126609A1 (en) 2015-05-07
EP2327398A3 (en) 2014-05-21
TW201436824A (zh) 2014-10-01
EP2327398A2 (en) 2011-06-01
US8969324B2 (en) 2015-03-03
IL203064B (en) 2018-02-28
RU2010105847A (ru) 2011-08-27
US9254326B2 (en) 2016-02-09
KR20100053563A (ko) 2010-05-20
TW200911273A (en) 2009-03-16
MX2010000693A (es) 2010-06-01
BRPI0814115B8 (pt) 2021-05-25
KR101485212B1 (ko) 2015-01-22
TWI446912B (zh) 2014-08-01
EP2178516A2 (en) 2010-04-28
RU2018113296A (ru) 2019-10-14
AU2008276840B2 (en) 2013-10-03
US20090022787A1 (en) 2009-01-22
NZ595270A (en) 2013-04-26
JP2014001247A (ja) 2014-01-09
BRPI0814115B1 (pt) 2019-04-02
JP2010533707A (ja) 2010-10-28

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