JP2010524963A5 - - Google Patents

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Publication number
JP2010524963A5
JP2010524963A5 JP2010504247A JP2010504247A JP2010524963A5 JP 2010524963 A5 JP2010524963 A5 JP 2010524963A5 JP 2010504247 A JP2010504247 A JP 2010504247A JP 2010504247 A JP2010504247 A JP 2010504247A JP 2010524963 A5 JP2010524963 A5 JP 2010524963A5
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JP
Japan
Prior art keywords
ion
pairing agent
lipoic acid
pharmaceutical formulation
item
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010504247A
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English (en)
Japanese (ja)
Other versions
JP2010524963A (ja
JP5480804B2 (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/060650 external-priority patent/WO2008131114A2/en
Publication of JP2010524963A publication Critical patent/JP2010524963A/ja
Publication of JP2010524963A5 publication Critical patent/JP2010524963A5/ja
Application granted granted Critical
Publication of JP5480804B2 publication Critical patent/JP5480804B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2010504247A 2007-04-18 2008-04-17 リポ酸誘導体を含有する医薬製剤 Expired - Fee Related JP5480804B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US91260507P 2007-04-18 2007-04-18
US60/912,605 2007-04-18
PCT/US2008/060650 WO2008131114A2 (en) 2007-04-18 2008-04-17 Pharmaceutical formulations containing lipoic acid derivatives

Publications (3)

Publication Number Publication Date
JP2010524963A JP2010524963A (ja) 2010-07-22
JP2010524963A5 true JP2010524963A5 (enExample) 2012-05-31
JP5480804B2 JP5480804B2 (ja) 2014-04-23

Family

ID=39872894

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010504247A Expired - Fee Related JP5480804B2 (ja) 2007-04-18 2008-04-17 リポ酸誘導体を含有する医薬製剤

Country Status (19)

Country Link
US (4) US20080262077A1 (enExample)
EP (1) EP2144609B1 (enExample)
JP (1) JP5480804B2 (enExample)
KR (1) KR101539785B1 (enExample)
CN (1) CN101820875B (enExample)
AR (1) AR067309A1 (enExample)
AU (1) AU2008242827B2 (enExample)
BR (1) BRPI0810439B1 (enExample)
CA (1) CA2684479C (enExample)
CL (1) CL2008001124A1 (enExample)
ES (1) ES2528414T3 (enExample)
IL (1) IL201581A (enExample)
MX (1) MX2009011165A (enExample)
NZ (1) NZ580973A (enExample)
PL (1) PL2144609T3 (enExample)
PT (1) PT2144609E (enExample)
SA (1) SA08290240B1 (enExample)
TW (1) TWI459944B (enExample)
WO (1) WO2008131114A2 (enExample)

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US8263653B2 (en) 2007-04-18 2012-09-11 Cornerstone Pharmaceuticals, Inc. Pharmaceutical formulations containing lipoic acid derivatives
MX2009011165A (es) 2007-04-18 2009-12-09 Cornerstone Pharmaceuticals In Formulaciones farmaceuticas que contienen derivados del acido lipoico.
ES2442901T3 (es) * 2007-04-18 2014-02-14 Cornerstone Pharmaceuticals, Inc. Derivados de ácido lipoico
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SI2506857T1 (en) 2009-12-01 2018-08-31 Translate Bio, Inc. Delivery of mRNA for the enrichment of proteins and enzymes in human genetic diseases
WO2011143590A1 (en) * 2010-05-14 2011-11-17 Cornerstone Pharmaceuticals, Inc. Combination therapy compositions and methods using lipoic acid derivatives and an anti-proliferation agent
WO2011143593A1 (en) * 2010-05-14 2011-11-17 Cornerstone Pharmaceuticals, Inc. Conjugates of a lipoic acid derivative and anti-proliferation agent and medical uses thereof
KR20220025112A (ko) 2011-06-08 2022-03-03 샤이어 휴먼 지네틱 테라피즈 인크. Mrna 전달을 위한 지질 나노입자 조성물 및 방법
CN102657606B (zh) * 2012-05-25 2014-01-01 江苏神龙药业有限公司 一种供静脉给药用的硫辛酸注射液
EP3536787A1 (en) 2012-06-08 2019-09-11 Translate Bio, Inc. Nuclease resistant polynucleotides and uses thereof
BR112015014327A2 (pt) * 2012-12-19 2020-01-28 Cornerstone Pharmaceuticals Inc compostos farmacêuticos
KR102311614B1 (ko) 2013-03-14 2021-10-08 샤이어 휴먼 지네틱 테라피즈 인크. Cftr mrna 조성물 및 관련 방법 및 사용
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CN103360437B (zh) * 2013-04-27 2015-10-21 江苏教育学院 一种硫辛酸糖类衍生物及其制备方法和在制备抗肿瘤药物中的应用
CN103497344B (zh) * 2013-09-25 2015-09-23 深圳先进技术研究院 用于负载贵金属颗粒的纳米凝胶及其制备方法与应用
ES2707966T3 (es) 2013-10-22 2019-04-08 Translate Bio Inc Terapia de ARNm para la deficiencia en síntesis de argininosuccinato
EP3574923A1 (en) 2013-10-22 2019-12-04 Translate Bio, Inc. Mrna therapy for phenylketonuria
EP4729528A3 (en) 2014-04-25 2026-06-24 Translate Bio, Inc. Methods for purification of messenger rna
ES2747702T3 (es) * 2014-06-19 2020-03-11 Rafael Pharmaceuticals Inc Compuestos farmacéuticos
EP3189033B1 (en) * 2014-06-19 2020-08-05 Rafael Pharmaceuticals, Inc. Pharmaceutical compounds
MX2019010155A (es) 2017-02-27 2020-12-10 Translate Bio Inc Arnm de cftr optimizado por codón novedoso.
IL270631B2 (en) 2017-05-16 2024-03-01 Translate Bio Inc Treatment of cystic fibrosis by delivery of codon-optimized mrna encoding cftr
US11174500B2 (en) 2018-08-24 2021-11-16 Translate Bio, Inc. Methods for purification of messenger RNA
AU2019384557B2 (en) 2018-11-21 2025-07-17 Translate Bio, Inc. Treatment of cystic fibrosis by delivery of nebulized mRNA encoding CFTR
TW202114651A (zh) * 2019-08-16 2021-04-16 美商拉斐爾製藥公司 用於治療癌症之方法及含有４，６—雙（苄硫基）己酸之藥物組成物
CA3155003A1 (en) 2019-09-20 2021-03-25 Translate Bio, Inc. Mrna encoding engineered cftr
EP4110308A4 (en) * 2020-02-28 2024-03-20 University Of Florida Research Foundation, Incorporated ANTI-TUMOR IMMUNITY MODULATING COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
JP2023549086A (ja) * 2020-11-03 2023-11-22 コーナーストーン ファーマシューティカルズ，インコーポレーテッド デビミスタットを使用して胆道癌を治療するための治療法及び組成物
CN119770650A (zh) * 2025-01-09 2025-04-08 华中科技大学 一种硫辛酸-胆碱离子液体溶液及其制备方法和应用

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ES2442901T3 (es) * 2007-04-18 2014-02-14 Cornerstone Pharmaceuticals, Inc. Derivados de ácido lipoico
US8263653B2 (en) * 2007-04-18 2012-09-11 Cornerstone Pharmaceuticals, Inc. Pharmaceutical formulations containing lipoic acid derivatives
MX2009011165A (es) 2007-04-18 2009-12-09 Cornerstone Pharmaceuticals In Formulaciones farmaceuticas que contienen derivados del acido lipoico.

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