JP2010523684A - テトラサイクリン化合物を用いる、脊髄筋委縮症を治療するための方法 - Google Patents

テトラサイクリン化合物を用いる、脊髄筋委縮症を治療するための方法 Download PDF

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JP2010523684A
JP2010523684A JP2010503091A JP2010503091A JP2010523684A JP 2010523684 A JP2010523684 A JP 2010523684A JP 2010503091 A JP2010503091 A JP 2010503091A JP 2010503091 A JP2010503091 A JP 2010503091A JP 2010523684 A JP2010523684 A JP 2010523684A
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alkyl
aryl
hydrogen
carbonyl
amino
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JP2010523684A5 (https=
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ジョエル ベルニア，
トッド バウザー，
マイケル ドレイパー，
ステュワート ビー． レビー，
マーク エル． ネルソン，
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パラテック ファーマシューティカルズ インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2010503091A 2007-04-12 2008-04-14 テトラサイクリン化合物を用いる、脊髄筋委縮症を治療するための方法 Pending JP2010523684A (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US92303107P 2007-04-12 2007-04-12
US93088307P 2007-05-18 2007-05-18
US94611007P 2007-06-25 2007-06-25
US99416307P 2007-09-18 2007-09-18
US98619207P 2007-11-07 2007-11-07
PCT/US2008/004827 WO2008127722A1 (en) 2007-04-12 2008-04-14 Methods for treating spinal muscular atrophy using tetracycline compounds

Publications (2)

Publication Number Publication Date
JP2010523684A true JP2010523684A (ja) 2010-07-15
JP2010523684A5 JP2010523684A5 (https=) 2011-06-02

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JP2010503091A Pending JP2010523684A (ja) 2007-04-12 2008-04-14 テトラサイクリン化合物を用いる、脊髄筋委縮症を治療するための方法

Country Status (6)

Country Link
US (2) US7935687B2 (https=)
EP (1) EP2144614A1 (https=)
JP (1) JP2010523684A (https=)
AU (1) AU2008239606A1 (https=)
CA (1) CA2688725A1 (https=)
WO (1) WO2008127722A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015519369A (ja) * 2012-05-30 2015-07-09 パラテック ファーマシューティカルズ インコーポレイテッド ７−二置換フェニルテトラサイクリン誘導体

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AU2017283546C1 (en) 2016-06-13 2020-11-19 Scholar Rock, Inc. Use of myostatin inhibitors and combination therapies
HUE066360T2 (hu) 2016-10-19 2024-07-28 Tetraphase Pharmaceuticals Inc Eravaciklin kristályformái
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WO2022093724A1 (en) 2020-10-26 2022-05-05 Scholar Rock, Inc. Use of anti-pro/latent myostatin antibody for treating spinal muscular atrophy
DK4518970T3 (da) 2022-05-04 2026-04-07 Scholar Rock Inc Anvendelse af myostatinhæmmer til behandling af spinal muskelatrofi
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JP2015519369A (ja) * 2012-05-30 2015-07-09 パラテック ファーマシューティカルズ インコーポレイテッド ７−二置換フェニルテトラサイクリン誘導体
JP2018083815A (ja) * 2012-05-30 2018-05-31 パラテック ファーマシューティカルズ インコーポレイテッド ７−二置換フェニルテトラサイクリン誘導体

Also Published As

Publication number Publication date
EP2144614A1 (en) 2010-01-20
AU2008239606A1 (en) 2008-10-23
CA2688725A1 (en) 2008-10-23
US20110207706A1 (en) 2011-08-25
US8399437B2 (en) 2013-03-19
US20090118269A1 (en) 2009-05-07
US7935687B2 (en) 2011-05-03
WO2008127722A1 (en) 2008-10-23

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