JP2010523684A - テトラサイクリン化合物を用いる、脊髄筋委縮症を治療するための方法 - Google Patents

テトラサイクリン化合物を用いる、脊髄筋委縮症を治療するための方法 Download PDF

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Publication number
JP2010523684A
JP2010523684A JP2010503091A JP2010503091A JP2010523684A JP 2010523684 A JP2010523684 A JP 2010523684A JP 2010503091 A JP2010503091 A JP 2010503091A JP 2010503091 A JP2010503091 A JP 2010503091A JP 2010523684 A JP2010523684 A JP 2010523684A
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alkyl
aryl
hydrogen
carbonyl
amino
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JP2010523684A5 (enExample
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ジョエル ベルニア，
トッド バウザー，
マイケル ドレイパー，
ステュワート ビー． レビー，
マーク エル． ネルソン，
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パラテック ファーマシューティカルズ インコーポレイテッド
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Publication of JP2010523684A publication Critical patent/JP2010523684A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2010503091A 2007-04-12 2008-04-14 テトラサイクリン化合物を用いる、脊髄筋委縮症を治療するための方法 Pending JP2010523684A (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US92303107P 2007-04-12 2007-04-12
US93088307P 2007-05-18 2007-05-18
US94611007P 2007-06-25 2007-06-25
US99416307P 2007-09-18 2007-09-18
US98619207P 2007-11-07 2007-11-07
PCT/US2008/004827 WO2008127722A1 (en) 2007-04-12 2008-04-14 Methods for treating spinal muscular atrophy using tetracycline compounds

Publications (2)

Publication Number Publication Date
JP2010523684A true JP2010523684A (ja) 2010-07-15
JP2010523684A5 JP2010523684A5 (enExample) 2011-06-02

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JP2010503091A Pending JP2010523684A (ja) 2007-04-12 2008-04-14 テトラサイクリン化合物を用いる、脊髄筋委縮症を治療するための方法

Country Status (6)

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US (2) US7935687B2 (enExample)
EP (1) EP2144614A1 (enExample)
JP (1) JP2010523684A (enExample)
AU (1) AU2008239606A1 (enExample)
CA (1) CA2688725A1 (enExample)
WO (1) WO2008127722A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
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JP2015519369A (ja) * 2012-05-30 2015-07-09 パラテック ファーマシューティカルズ インコーポレイテッド ７−二置換フェニルテトラサイクリン誘導体

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KR101228706B1 (ko) * 2003-07-09 2013-02-01 파라테크 파마슈티컬스, 인크. 치환된 테트라시클린 화합물
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AU2007249695A1 (en) * 2006-05-15 2007-11-22 Paratek Pharmaceuticals, Inc. Methods of regulating expression of genes or of gene products using substituted tetracycline compounds
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CN105367440A (zh) 2008-08-08 2016-03-02 四相制药公司 C7-氟取代的四环素化合物
EP2341771A4 (en) * 2008-09-19 2012-08-15 Paratek Pharm Innc TETRACYCLINE COMPOUNDS FOR THE TREATMENT OF RHEUMATOID ARTHRITIS AND RELATED THERAPEUTIC METHODS
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KR102271635B1 (ko) 2016-06-13 2021-07-06 스칼러 락, 인크. 미오스타틴 억제제의 용도 및 조합 요법
DK3529236T3 (da) 2016-10-19 2024-05-13 Tetraphase Pharmaceuticals Inc Krystalformer af eravacyclin
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KR20230095998A (ko) 2020-10-26 2023-06-29 스칼러 락, 인크. 척수 근위축증을 치료하기 위한 항-프로/잠재성 마이오스타틴 항체의 용도
KR20250021401A (ko) 2022-05-04 2025-02-12 스칼러 락, 인크. 척수 근위축증을 치료하기 위한 마이오스타틴 저해제의 용도

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JP2015519369A (ja) * 2012-05-30 2015-07-09 パラテック ファーマシューティカルズ インコーポレイテッド ７−二置換フェニルテトラサイクリン誘導体
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Also Published As

Publication number Publication date
US8399437B2 (en) 2013-03-19
WO2008127722A1 (en) 2008-10-23
EP2144614A1 (en) 2010-01-20
AU2008239606A1 (en) 2008-10-23
CA2688725A1 (en) 2008-10-23
US20110207706A1 (en) 2011-08-25
US20090118269A1 (en) 2009-05-07
US7935687B2 (en) 2011-05-03

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