JP2010523684A - テトラサイクリン化合物を用いる、脊髄筋委縮症を治療するための方法 - Google Patents

テトラサイクリン化合物を用いる、脊髄筋委縮症を治療するための方法 Download PDF

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JP2010523684A
JP2010523684A JP2010503091A JP2010503091A JP2010523684A JP 2010523684 A JP2010523684 A JP 2010523684A JP 2010503091 A JP2010503091 A JP 2010503091A JP 2010503091 A JP2010503091 A JP 2010503091A JP 2010523684 A JP2010523684 A JP 2010523684A
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alkyl
aryl
hydrogen
carbonyl
amino
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JP2010523684A5 (enExample
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ジョエル ベルニア，
トッド バウザー，
マイケル ドレイパー，
ステュワート ビー． レビー，
マーク エル． ネルソン，
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パラテック ファーマシューティカルズ インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2010503091A 2007-04-12 2008-04-14 テトラサイクリン化合物を用いる、脊髄筋委縮症を治療するための方法 Pending JP2010523684A (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US92303107P 2007-04-12 2007-04-12
US93088307P 2007-05-18 2007-05-18
US94611007P 2007-06-25 2007-06-25
US99416307P 2007-09-18 2007-09-18
US98619207P 2007-11-07 2007-11-07
PCT/US2008/004827 WO2008127722A1 (en) 2007-04-12 2008-04-14 Methods for treating spinal muscular atrophy using tetracycline compounds

Publications (2)

Publication Number Publication Date
JP2010523684A true JP2010523684A (ja) 2010-07-15
JP2010523684A5 JP2010523684A5 (enExample) 2011-06-02

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JP2010503091A Pending JP2010523684A (ja) 2007-04-12 2008-04-14 テトラサイクリン化合物を用いる、脊髄筋委縮症を治療するための方法

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US (2) US7935687B2 (enExample)
EP (1) EP2144614A1 (enExample)
JP (1) JP2010523684A (enExample)
AU (1) AU2008239606A1 (enExample)
CA (1) CA2688725A1 (enExample)
WO (1) WO2008127722A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
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JP2015519369A (ja) * 2012-05-30 2015-07-09 パラテック ファーマシューティカルズ インコーポレイテッド ７−二置換フェニルテトラサイクリン誘導体

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WO2010033939A1 (en) * 2008-09-19 2010-03-25 Paratek Pharmaceuticals, Inc. Tetracycline compounds for the treatment of rheumatoid arthritis and related methods of treatment
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LT3368069T (lt) 2016-06-13 2020-12-10 Scholar Rock, Inc. Miostatino inhibitorių naudojimas, ir kombinuotas gydymas
KR102880712B1 (ko) 2016-10-19 2025-11-03 테트라페이즈 파마슈티컬스, 인코포레이티드 에라바사이클린의 결정질 형태
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CA3193909A1 (en) 2020-10-26 2022-05-05 George NOMIKOS Use of anti-pro/latent myostatin antibody for treating spinal muscular atrophy
WO2023215384A2 (en) 2022-05-04 2023-11-09 Scholar Rock, Inc. Use of myostatin inhibitor for treating spinal muscular atrophy

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JP2018083815A (ja) * 2012-05-30 2018-05-31 パラテック ファーマシューティカルズ インコーポレイテッド ７−二置換フェニルテトラサイクリン誘導体

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US20110207706A1 (en) 2011-08-25
US7935687B2 (en) 2011-05-03
AU2008239606A1 (en) 2008-10-23
US8399437B2 (en) 2013-03-19
US20090118269A1 (en) 2009-05-07
CA2688725A1 (en) 2008-10-23
EP2144614A1 (en) 2010-01-20
WO2008127722A1 (en) 2008-10-23

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