JP2010523644A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2010523644A5 JP2010523644A5 JP2010502609A JP2010502609A JP2010523644A5 JP 2010523644 A5 JP2010523644 A5 JP 2010523644A5 JP 2010502609 A JP2010502609 A JP 2010502609A JP 2010502609 A JP2010502609 A JP 2010502609A JP 2010523644 A5 JP2010523644 A5 JP 2010523644A5
- Authority
- JP
- Japan
- Prior art keywords
- amino
- dione
- trifluoromethyl
- methyl
- pyridyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CCC[C@](C)C(Cc1ncc(*)c*1C(F)(F)F)N(C(C(Br)=C1Br)=O)C1=O Chemical compound CCC[C@](C)C(Cc1ncc(*)c*1C(F)(F)F)N(C(C(Br)=C1Br)=O)C1=O 0.000 description 16
- ORIDHTHFLIVCEP-UHFFFAOYSA-N CC(C(CC1CNc2cc(Cl)c(ccc3c4cccc3)c4n2)=O)=C(C)C1=O Chemical compound CC(C(CC1CNc2cc(Cl)c(ccc3c4cccc3)c4n2)=O)=C(C)C1=O ORIDHTHFLIVCEP-UHFFFAOYSA-N 0.000 description 1
- XDTSESNHCPGWRH-UHFFFAOYSA-N CC(C(CCC1CNc2cc(Cl)c(ccc(Br)c3)c3n2)=O)=C(C)C1=O Chemical compound CC(C(CCC1CNc2cc(Cl)c(ccc(Br)c3)c3n2)=O)=C(C)C1=O XDTSESNHCPGWRH-UHFFFAOYSA-N 0.000 description 1
- UTLKHLBMVYBHDN-UHFFFAOYSA-N CC(O)OCC1=CC(NC(C)(CC(C(C)=C2C)O)C2O)NC2=C1CCC(Br)=C2 Chemical compound CC(O)OCC1=CC(NC(C)(CC(C(C)=C2C)O)C2O)NC2=C1CCC(Br)=C2 UTLKHLBMVYBHDN-UHFFFAOYSA-N 0.000 description 1
- HFBOMJUKXJADCC-AQHIEDMUSA-N CCBC1=CC(C(F)(F)F)=CC(C(C)N(/C(/C(C(C)C)=C2C3CNCC3)=C\CC)C2=O)=C(C)C1 Chemical compound CCBC1=CC(C(F)(F)F)=CC(C(C)N(/C(/C(C(C)C)=C2C3CNCC3)=C\CC)C2=O)=C(C)C1 HFBOMJUKXJADCC-AQHIEDMUSA-N 0.000 description 1
- HVFNUJBEIHOLQX-UHFFFAOYSA-N CCC(CCC(C(N1Nc2nc(Cl)c(C(F)(F)I)cc2)=O)=C(C)C1=O)O Chemical compound CCC(CCC(C(N1Nc2nc(Cl)c(C(F)(F)I)cc2)=O)=C(C)C1=O)O HVFNUJBEIHOLQX-UHFFFAOYSA-N 0.000 description 1
- RFPNKBGFFAGOCP-UHFFFAOYSA-N CCSC(C(C=O)N1Cc2ccccc2O)=C(C)C1=O Chemical compound CCSC(C(C=O)N1Cc2ccccc2O)=C(C)C1=O RFPNKBGFFAGOCP-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91125807P | 2007-04-11 | 2007-04-11 | |
| US60/911,258 | 2007-04-11 | ||
| PCT/IB2008/003036 WO2009031040A2 (en) | 2007-04-11 | 2008-04-11 | Compounds with anti-cancer activity |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013176324A Division JP2014012706A (ja) | 2007-04-11 | 2013-08-28 | 抗がん活性を有する化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010523644A JP2010523644A (ja) | 2010-07-15 |
| JP2010523644A5 true JP2010523644A5 (OSRAM) | 2011-05-12 |
| JP5635396B2 JP5635396B2 (ja) | 2014-12-03 |
Family
ID=39939984
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010502609A Active JP5635396B2 (ja) | 2007-04-11 | 2008-04-11 | 抗がん活性を有する化合物 |
| JP2013176324A Withdrawn JP2014012706A (ja) | 2007-04-11 | 2013-08-28 | 抗がん活性を有する化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013176324A Withdrawn JP2014012706A (ja) | 2007-04-11 | 2013-08-28 | 抗がん活性を有する化合物 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US8084454B2 (OSRAM) |
| EP (4) | EP3567035B1 (OSRAM) |
| JP (2) | JP5635396B2 (OSRAM) |
| KR (1) | KR101475311B1 (OSRAM) |
| CN (2) | CN101720323A (OSRAM) |
| AU (1) | AU2008294410B2 (OSRAM) |
| BR (2) | BR122022005149B1 (OSRAM) |
| CA (4) | CA2913840C (OSRAM) |
| DK (2) | DK3567035T3 (OSRAM) |
| ES (3) | ES2594704T3 (OSRAM) |
| HU (2) | HUE029370T2 (OSRAM) |
| IL (4) | IL309201A (OSRAM) |
| MX (3) | MX391154B (OSRAM) |
| NZ (1) | NZ580237A (OSRAM) |
| RU (1) | RU2482111C2 (OSRAM) |
| WO (1) | WO2009031040A2 (OSRAM) |
| ZA (1) | ZA200906960B (OSRAM) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2913840C (en) * | 2007-04-11 | 2019-03-05 | Canbas Co., Ltd. | Compounds with anti-cancer activity |
| WO2010006291A1 (en) | 2008-07-10 | 2010-01-14 | Nodality, Inc. | Methods for diagnosis, prognosis and treatment |
| CN102405044A (zh) | 2009-02-06 | 2012-04-04 | 南加利福尼亚大学 | 含有单萜的治疗组合物 |
| US20100215644A1 (en) * | 2009-02-25 | 2010-08-26 | Nodality, Inc. A Delaware Corporation | Analysis of nodes in cellular pathways |
| US8507734B2 (en) | 2010-03-03 | 2013-08-13 | Neonc Technologies Inc. | Pharmaceutical compositions comprising monoterpenes |
| US20160038600A1 (en) | 2012-08-03 | 2016-02-11 | Neonc Technologies Inc. | Pharmaceutical compositions comprising poh derivatives |
| EP2609064B1 (en) | 2010-08-27 | 2016-09-28 | Neonc Technologies Inc. | Pharmaceutical compositions comprising derivatives of perillyl alcohol |
| US9211269B2 (en) | 2010-12-17 | 2015-12-15 | Neonc Technologies Inc. | Methods and devices for using isoperillyl alcohol |
| WO2013020024A2 (en) * | 2011-08-03 | 2013-02-07 | Karyopharm Therapeutics, Inc. | Maleimide compounds and methods of treatment |
| WO2013169600A1 (en) * | 2012-05-09 | 2013-11-14 | Delmar Pharmaceuticals | Veterinary use of dianhydrogalactitol, diacetyldianhydrogalactitol, and dibromodulcitol to treat malignancies |
| ES2563861T3 (es) | 2012-06-14 | 2016-03-16 | Daiichi Sankyo Company, Limited | Derivado de piperidinilpirazolopiridina |
| HK1215250A1 (zh) * | 2013-01-30 | 2016-08-19 | Bayer Pharma Aktiengesellschaft | 氨基取代的异噻唑 |
| US9540462B2 (en) | 2014-12-05 | 2017-01-10 | Massachusetts Institute Of Technology | Catechol-rich polymers from N-substituted maleimides |
| DK3250550T3 (da) | 2015-01-26 | 2023-07-17 | Ottawa Hospital Res Inst | Sammensætninger og fremgangsmåder til virussensibilisering |
| EP3261441B1 (en) | 2015-02-12 | 2020-09-09 | Neonc Technologies Inc. | Pharmaceutical compositions comprising perillyl alcohol derivatives |
| TW201808906A (zh) | 2016-03-16 | 2018-03-16 | 拜耳作物科學股份有限公司 | 作為殺蟲劑之經取代吡啶化合物 |
| USD801721S1 (en) | 2016-03-31 | 2017-11-07 | Patricia Grayson Briden | Spooled item holding device |
| USD915100S1 (en) | 2016-03-31 | 2021-04-06 | Ocean 22, Llc | Spooled item holding device |
| TW201811766A (zh) | 2016-08-29 | 2018-04-01 | 瑞士商諾華公司 | N-(吡啶-2-基)吡啶-磺醯胺衍生物及其用於疾病治療之用途 |
| CN111867573A (zh) | 2018-01-29 | 2020-10-30 | 科诺斯治疗学公司 | 硼替佐米的瘤内递送 |
| EP3746451B1 (en) | 2018-02-02 | 2023-07-12 | Boehringer Ingelheim International GmbH | Benzyl-, (pyridin-3-yl)methyl- or (pyridin-4-yl)methyl-substituted oxadiazolopyridine derivatives as ghrelin o-acyl transferase (goat) inhibitors |
| MX2020007994A (es) | 2018-02-02 | 2020-09-09 | Boehringer Ingelheim Int | Derivados de triazolopirimidina para usar como inhibidores de ghrelin o-aciltransferasa (goat). |
| CA3225993A1 (en) | 2018-02-08 | 2019-08-15 | University Of Southern California | The use of monoterpene, sesquiterpene, or their derivatives to permeabilize the blood brain barrier |
| EP4153600B1 (en) | 2020-05-22 | 2024-08-07 | Boehringer Ingelheim International GmbH | Continuous process for manufacturing alkyl 7-amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridine-carboxylate |
| WO2021233882A1 (en) | 2020-05-22 | 2021-11-25 | Boehringer Ingelheim International Gmbh | Process for manufacturing alkyl 7-amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridine-carboxylate |
| US20250017889A1 (en) * | 2021-10-15 | 2025-01-16 | The Curators Of The University Of Missouri | Inhibitors of p1b-type atpases |
| CN114425054A (zh) * | 2022-01-20 | 2022-05-03 | 中国人民解放军军事科学院军事医学研究院 | 一种蛋白酶体抑制剂Bortezomib在抗辐射损伤中的用途 |
| CN120247782B (zh) * | 2025-06-04 | 2025-08-19 | 北京颖泰嘉和生物科技股份有限公司 | 氟吡菌酰胺类化合物及其制备方法 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5564557A (en) * | 1978-11-08 | 1980-05-15 | Mitsui Toatsu Chem Inc | Diphenyl ether compound and herbicide containing the same |
| IL81307A0 (en) * | 1986-01-23 | 1987-08-31 | Union Carbide Agricult | Method for reducing moisture loss from plants and increasing crop yield utilizing nitrogen containing heterocyclic compounds and some novel polysubstituted pyridine derivatives |
| US5635966A (en) * | 1994-01-11 | 1997-06-03 | Hewlett-Packard Company | Edge feed ink delivery thermal inkjet printhead structure and method of fabrication |
| JPH07224032A (ja) * | 1994-02-09 | 1995-08-22 | Mitsui Petrochem Ind Ltd | Ｎ−アリールオキシフタルイミド誘導体、その製造方 法及びそれを有効成分として含有する除草剤 |
| JPH07244032A (ja) * | 1994-03-01 | 1995-09-19 | Ishikawajima Harima Heavy Ind Co Ltd | 溶接部検査装置 |
| AU726058B2 (en) | 1995-09-01 | 2000-10-26 | Signal Pharmaceuticals, Inc. | Pyrimidine carboxylates and related compounds and methods for treating inflammatory conditions |
| US5935966A (en) * | 1995-09-01 | 1999-08-10 | Signal Pharmaceuticals, Inc. | Pyrimidine carboxylates and related compounds and methods for treating inflammatory conditions |
| CA2245029A1 (en) * | 1998-03-13 | 1999-09-13 | University Of British Columbia | Granulatimide compounds as g2 checkpoint inhibitors |
| US6205557B1 (en) | 1998-06-09 | 2001-03-20 | At&T Corp. | Redundant call processing |
| EP1133229B1 (de) * | 1998-11-24 | 2002-10-09 | Basf Aktiengesellschaft | Fungizide mittel enthaltend als wirkstoffe pyrrolidone |
| CA2385257A1 (en) | 1999-09-22 | 2001-03-29 | Canbas Co., Ltd. | Compositions and methods for inhibiting g2 cell cycle arrest and sensitizing cells to dna damaging agents |
| WO2001062087A2 (de) * | 2000-02-26 | 2001-08-30 | Basf Aktiengesellschaft | Fungizide mittel enthaltend als wirkstoffe pyrrolidone und deren verwendung bei der behandlung von pflanzen |
| JP2002318434A (ja) * | 2001-04-23 | 2002-10-31 | Konica Corp | ハロゲン化銀写真感光材料、処理方法、および画像形成方法 |
| FR2826653B1 (fr) * | 2001-06-29 | 2005-10-14 | Servier Lab | Nouveaux derives de pyrido-pyrido-pyrrolo[3,2-g]pyrrolo [3,4-e]-indole et pyrido-pyrrolo[2,3-a]pyrrolo[3,4-c] carbazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| ATE520653T1 (de) * | 2002-06-06 | 2011-09-15 | Canbas Co Ltd | Verbindungen, die den durch dna-schädigung induzierten g2-checkpoint des zellzyklus stilllegen und/oder die antikrebswirkung von dna- schädigenden behandlungen erhöhen |
| WO2005024755A2 (en) * | 2002-12-31 | 2005-03-17 | Deciphera Pharmaceuticals, Llc. | Medicaments for the treatment of neurodegenerative disorders or diabetes |
| US7572816B2 (en) * | 2003-08-01 | 2009-08-11 | Auspex Pharmaceuticals, Inc. | Therapeutic agents for the treatment of cancer, metabolic diseases and skin disorders |
| CA2558600C (en) * | 2004-03-10 | 2013-07-09 | Kureha Corporation | A substituted-trialkyl amine compound with anti-viral activity based on antagonism against a chemokine receptor cxcr4 |
| JP2008502595A (ja) * | 2004-03-31 | 2008-01-31 | エグゼリクシス， インコーポレイテッド | 未分化リンパ腫キナーゼモジュレータおよびその使用方法 |
| EP1851203A2 (en) * | 2005-02-08 | 2007-11-07 | Merck & Co., Inc. | Inhibitors of checkpoint kinases |
| JP4976394B2 (ja) * | 2005-08-17 | 2012-07-18 | シェーリング コーポレイション | 新規な高親和性のキノリンベースのキナーゼリガンド |
| US20070117808A1 (en) | 2005-11-01 | 2007-05-24 | Maud Urbanski | Substituted Cycloalkylpyrrolones As Allosteric Modulators Of Glucokinase |
| WO2007114338A1 (ja) * | 2006-03-31 | 2007-10-11 | Takeda Pharmaceutical Company Limited | 酸分泌抑制薬 |
| WO2008110891A2 (en) * | 2007-03-09 | 2008-09-18 | Orchid Research Laboratories Limited, | New heterocyclic compounds |
| CA2913840C (en) | 2007-04-11 | 2019-03-05 | Canbas Co., Ltd. | Compounds with anti-cancer activity |
-
2008
- 2008-04-11 CA CA2913840A patent/CA2913840C/en active Active
- 2008-04-11 EP EP19167943.0A patent/EP3567035B1/en active Active
- 2008-04-11 HU HUE08829410A patent/HUE029370T2/hu unknown
- 2008-04-11 JP JP2010502609A patent/JP5635396B2/ja active Active
- 2008-04-11 DK DK19167943.0T patent/DK3567035T3/da active
- 2008-04-11 WO PCT/IB2008/003036 patent/WO2009031040A2/en not_active Ceased
- 2008-04-11 IL IL309201A patent/IL309201A/en unknown
- 2008-04-11 ES ES08829410.3T patent/ES2594704T3/es active Active
- 2008-04-11 ES ES16165912T patent/ES2732230T3/es active Active
- 2008-04-11 KR KR1020097023566A patent/KR101475311B1/ko active Active
- 2008-04-11 MX MX2020009403A patent/MX391154B/es unknown
- 2008-04-11 CA CA3188320A patent/CA3188320A1/en active Pending
- 2008-04-11 AU AU2008294410A patent/AU2008294410B2/en active Active
- 2008-04-11 NZ NZ580237A patent/NZ580237A/en unknown
- 2008-04-11 CA CA3030510A patent/CA3030510C/en active Active
- 2008-04-11 MX MX2009011025A patent/MX2009011025A/es unknown
- 2008-04-11 EP EP08829410.3A patent/EP2152692B9/en active Active
- 2008-04-11 BR BR122022005149-9A patent/BR122022005149B1/pt active IP Right Grant
- 2008-04-11 MX MX2015016591A patent/MX374896B/es unknown
- 2008-04-11 CA CA2684037A patent/CA2684037C/en active Active
- 2008-04-11 BR BRPI0810911-7A patent/BRPI0810911B1/pt active IP Right Grant
- 2008-04-11 HU HUE19167943A patent/HUE059861T2/hu unknown
- 2008-04-11 CN CN200880019414A patent/CN101720323A/zh active Pending
- 2008-04-11 DK DK08829410.3T patent/DK2152692T3/en active
- 2008-04-11 CN CN201510578313.XA patent/CN105175394B/zh active Active
- 2008-04-11 RU RU2009141619/04A patent/RU2482111C2/ru active
- 2008-04-11 IL IL289165A patent/IL289165B2/en unknown
- 2008-04-11 EP EP22176177.8A patent/EP4074704A1/en not_active Withdrawn
- 2008-04-11 US US12/082,643 patent/US8084454B2/en active Active
- 2008-04-11 ES ES19167943T patent/ES2927954T3/es active Active
- 2008-04-11 EP EP16165912.3A patent/EP3088397B1/en active Active
-
2009
- 2009-10-06 ZA ZA2009/06960A patent/ZA200906960B/en unknown
- 2009-10-11 IL IL201380A patent/IL201380A0/en active IP Right Grant
-
2010
- 2010-11-19 US US12/950,297 patent/US8415357B2/en active Active
-
2013
- 2013-08-28 JP JP2013176324A patent/JP2014012706A/ja not_active Withdrawn
-
2015
- 2015-12-02 IL IL242883A patent/IL242883B/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2010523644A5 (OSRAM) | ||
| RU2482111C2 (ru) | Соединения, обладающие противораковой активностью | |
| RU2451675C2 (ru) | ПРОИЗВОДНЫЕ 4-(2-АМИНО-1-ГИДРОКСИЭТИЛ)ФЕНОЛА В КАЧЕСТВЕ АГОНИСТОВ β2-АДРЕНЕРГИЧЕСКОГО РЕЦЕПТОРА | |
| CN1942186B (zh) | 吡咯烷化合物 | |
| JP2013515038A5 (OSRAM) | ||
| JP2013517283A5 (OSRAM) | ||
| JP2009524589A5 (ja) | 置換されたイソキノリン−１，３（２ｈ，４ｈ）−ジオン、１−チオキソ−１，４−ジヒドロ−２ｈ−イソキノリン−３−オン、および１，４−ジヒドロ−３（２ｈ）−イソキノロン、ならびにキナーゼインヒビターとしてのそれらの使用 | |
| JP2011520941A5 (OSRAM) | ||
| JP2013503901A5 (OSRAM) | ||
| HRP20110939T1 (hr) | Supstituirani benzimidazoli kao inhibitori kinaze | |
| JP2012520867A5 (OSRAM) | ||
| JP2007519754A5 (OSRAM) | ||
| KR20010006487A (ko) | 조합된 5ｈｔ1ａ, 5ｈｔ1ｂ 및 5ｈｔ1ｄ 수용체 길항 활성을 갖는 인돌 유도체 | |
| JP2009536620A5 (OSRAM) | ||
| JP2009541461A5 (OSRAM) | ||
| JP2005538955A5 (OSRAM) | ||
| JP2016506964A5 (ja) | ナトリウムチャネルの調節剤としてのキノリンおよびキノキサリンアミド | |
| JP2015500212A5 (OSRAM) | ||
| JP2006513202A5 (OSRAM) | ||
| RU2010110640A (ru) | Соединения и композиции 5-(4-(галогеналкокси)фенил)пиримидин-2-амина в качестве ингибиторов киназ | |
| CA2551508A1 (en) | Novel quinoline derivatives | |
| JP2010090138A5 (OSRAM) | ||
| JP2010513304A5 (OSRAM) | ||
| WO2006076575B1 (en) | Substituted biaryl compounds as factor xia inhibitors | |
| JP2010529991A5 (OSRAM) |