PL4153600T3 - Sposób ciągły wytwarzania 7-amino-5-metylo-[1,2,5]oksadiazolo[3,4- b]pirydynokarboksylanu alkilu - Google Patents
Sposób ciągły wytwarzania 7-amino-5-metylo-[1,2,5]oksadiazolo[3,4- b]pirydynokarboksylanu alkiluInfo
- Publication number
- PL4153600T3 PL4153600T3 PL21726390.4T PL21726390T PL4153600T3 PL 4153600 T3 PL4153600 T3 PL 4153600T3 PL 21726390 T PL21726390 T PL 21726390T PL 4153600 T3 PL4153600 T3 PL 4153600T3
- Authority
- PL
- Poland
- Prior art keywords
- oxadiazolo
- pyridinecarboxylate
- amino
- methyl
- continuous process
- Prior art date
Links
- 238000010924 continuous production Methods 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0006—Controlling or regulating processes
- B01J19/002—Avoiding undesirable reactions or side-effects, e.g. avoiding explosions, or improving the yield by suppressing side-reactions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00002—Chemical plants
- B01J2219/00027—Process aspects
- B01J2219/00029—Batch processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00002—Chemical plants
- B01J2219/00027—Process aspects
- B01J2219/00033—Continuous processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00049—Controlling or regulating processes
- B01J2219/00051—Controlling the temperature
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00049—Controlling or regulating processes
- B01J2219/00162—Controlling or regulating processes controlling the pressure
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20176117 | 2020-05-22 | ||
| PCT/EP2021/063090 WO2021233884A1 (en) | 2020-05-22 | 2021-05-18 | Continuous process for manufacturing alkyl 7-amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridine-carboxylate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL4153600T3 true PL4153600T3 (pl) | 2024-12-16 |
Family
ID=70802781
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL21726390.4T PL4153600T3 (pl) | 2020-05-22 | 2021-05-18 | Sposób ciągły wytwarzania 7-amino-5-metylo-[1,2,5]oksadiazolo[3,4- b]pirydynokarboksylanu alkilu |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11976082B2 (pl) |
| EP (1) | EP4153600B1 (pl) |
| JP (1) | JP7702969B2 (pl) |
| CN (1) | CN115916789B (pl) |
| DK (1) | DK4153600T3 (pl) |
| ES (1) | ES2991340T3 (pl) |
| HU (1) | HUE069479T2 (pl) |
| PL (1) | PL4153600T3 (pl) |
| TW (1) | TW202208378A (pl) |
| WO (1) | WO2021233884A1 (pl) |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002249492A (ja) | 2000-12-22 | 2002-09-06 | Nippon Bayer Agrochem Co Ltd | トリアゾロピリミジン類 |
| WO2004082383A1 (en) | 2003-03-17 | 2004-09-30 | Basf Aktiengesellschaft | Use of triazolopyrimidines for combating nematode diseases of plants |
| EP1660467B1 (en) * | 2003-08-20 | 2011-12-07 | Vertex Pharmaceuticals Incorporated | 2-(4-amino-1,2,5-oxadiazol-4-yl)-imidazole compounds useful as protein kinase inhibitors |
| EP1876899A2 (de) | 2005-04-25 | 2008-01-16 | Basf Aktiengesellschaft | Verwendung von 5-alkyl-6-phenylalkyl-7-amino-azolopyrimidinen, neue azolopyrimidine, verfahren zu ihrer herstellung und sie enthaltende mittel |
| KR20150116465A (ko) | 2007-02-15 | 2015-10-15 | 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 | 글루카곤/ｇｌｐ-1 수용체 공동-항진물질 |
| CA2913840C (en) | 2007-04-11 | 2019-03-05 | Canbas Co., Ltd. | Compounds with anti-cancer activity |
| JP5383661B2 (ja) | 2007-04-30 | 2014-01-08 | アッヴィ・インコーポレイテッド | ジアシルグリセロールｏ−アシル転移酵素１型酵素の阻害剤 |
| WO2008141843A1 (en) | 2007-05-24 | 2008-11-27 | Bayer Schering Pharma Aktiengesellschaft | Novel sulphoximine-substituted quinazoline and quinazoline derivatives as kinase inhibitors |
| ATE520714T1 (de) | 2007-06-15 | 2011-09-15 | Zealand Pharma As | Glucagonanaloga |
| FR2934058B1 (fr) | 2008-07-15 | 2010-09-24 | Centre Nat Rech Scient | Dispositif de projection interferometrique a trois ouvertures pour produire une tache constituee de structures fines |
| FR2933989B1 (fr) | 2008-07-16 | 2013-03-08 | Commissariat Energie Atomique | Procede de purification de microorganismes presents dans des echantillons liquides |
| FR2933975B1 (fr) | 2008-07-17 | 2011-02-18 | Servier Lab | Nouveau procede de preparation de benzocyclobutenes fonctionnalises,et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable. |
| MX2011006314A (es) | 2008-12-15 | 2011-09-22 | Zealand Pharma As | Analogos de glucagon. |
| PT2454282E (pt) | 2009-07-13 | 2015-06-23 | Zealand Pharma As | Análogos de glucagão acilados |
| WO2011114148A1 (en) | 2010-03-17 | 2011-09-22 | Astrazeneca Ab | 4h- [1, 2, 4] triazolo [5, 1 -b] pyrimidin-7 -one derivatives as ccr2b receptor antagonists |
| UY33462A (es) | 2010-06-23 | 2012-01-31 | Zealand Pharma As | Analogos de glucagon |
| US9169310B2 (en) | 2010-06-24 | 2015-10-27 | Zealand Pharma A/S | Glucagon analogues |
| US9802954B2 (en) * | 2011-08-24 | 2017-10-31 | Boehringer Ingelheim International Gmbh | Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma |
| CN103102348B (zh) * | 2011-11-14 | 2016-06-08 | 上海交通大学 | 噁二唑类化合物及其制备方法、药物组合物及其用途 |
| AP2014007797A0 (en) | 2011-12-23 | 2014-07-31 | Boehringer Ingelheim Int | Glucagon analogues |
| EP2838891B1 (en) | 2012-02-24 | 2017-08-02 | Takeda Pharmaceutical Company Limited | Aromatic ring compound as ghrelin o-acyltransferase inhibitor |
| WO2013192388A1 (en) | 2012-06-20 | 2013-12-27 | University Of Virginia Patent Foundation | Compositions and methods for regulating glucose homeostasis and insulin action |
| TWI608013B (zh) | 2012-09-17 | 2017-12-11 | 西蘭製藥公司 | 升糖素類似物 |
| UA118034C2 (uk) | 2013-11-14 | 2018-11-12 | Елі Ліллі Енд Компані | Заміщений піперидилетилпіримідин як інгібітор грелін-o-ацилтрансферази |
| WO2016044467A1 (en) | 2014-09-17 | 2016-03-24 | The Regents Of The University Of California | Small lipopeptidomimetic inhibitors of ghrelin o-acyl transferase |
| WO2016091746A1 (en) | 2014-12-11 | 2016-06-16 | Dsm Sinochem Pharmaceuticals Netherlands B.V. | Method for acylating a cyclic peptide |
| WO2016123275A1 (en) | 2015-01-30 | 2016-08-04 | Boehringer Ingelheim International Gmbh | Aldosterone synthase inhibitors |
| AR104673A1 (es) | 2015-04-15 | 2017-08-09 | Lilly Co Eli | Inhibidores de grelina o-aciltransferasa |
| AR104672A1 (es) | 2015-04-15 | 2017-08-09 | Lilly Co Eli | Inhibidores de grelina o-aciltransferasa |
| EP3364993B1 (en) | 2015-10-22 | 2022-11-09 | Cavion, Inc. | Methods for treating angelman syndrome |
| MA45843B1 (fr) | 2016-08-05 | 2021-06-30 | Boehringer Ingelheim Int | Dérivés d'oxadiazolopyridine utilisés comme inhibiteurs de la ghréline o-acyl transférase (chèvre) |
| US10988487B2 (en) | 2016-08-29 | 2021-04-27 | Merck Sharp & Dohme Corp. | Substituted n′-hydroxycarbamimidoyl-1,2,5-oxadiazole compounds as indoleamine 2,3-dioxygenase (IDO) inhibitors |
| KR102468876B1 (ko) * | 2016-12-27 | 2022-11-17 | 고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸 | 나프토비스칼코게나디아졸 유도체 및 그 제조 방법 |
| EP3746443B1 (en) | 2018-02-02 | 2022-07-06 | Boehringer Ingelheim International GmbH | Triazolopyrimidine derivatives for use as ghrelin o-acyl transferase (goat) inhibitors |
| EA202091804A1 (ru) | 2018-02-02 | 2020-12-24 | Бёрингер Ингельхайм Интернациональ Гмбх | Гетероциклил-замещенные оксадиазолопиридиновые производные для применения в качестве ингибиторов грелин-о-ацилтрансферазы (goat) |
| EP3746449B1 (en) | 2018-02-02 | 2022-03-30 | Boehringer Ingelheim International GmbH | Pyrazole- and indazole-substituted oxadiazolopyridine derivatives for use as ghrelin o-acyl transferase (goat) inhibitors |
| WO2019149657A1 (en) | 2018-02-02 | 2019-08-08 | Boehringer Ingelheim International Gmbh | Benzyl-, (pyridin-3-yl)methyl- or (pyridin-4-yl)methyl-substituted oxadiazolopyridine derivatives as ghrelin o-acyl transferase (goat) inhibitors |
| EP4153599B1 (en) * | 2020-05-22 | 2024-03-13 | Boehringer Ingelheim International GmbH | Process for manufacturing alkyl 7-amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridine-carboxylate |
-
2021
- 2021-05-18 HU HUE21726390A patent/HUE069479T2/hu unknown
- 2021-05-18 PL PL21726390.4T patent/PL4153600T3/pl unknown
- 2021-05-18 WO PCT/EP2021/063090 patent/WO2021233884A1/en not_active Ceased
- 2021-05-18 EP EP21726390.4A patent/EP4153600B1/en active Active
- 2021-05-18 DK DK21726390.4T patent/DK4153600T3/da active
- 2021-05-18 JP JP2022570159A patent/JP7702969B2/ja active Active
- 2021-05-18 ES ES21726390T patent/ES2991340T3/es active Active
- 2021-05-18 CN CN202180036761.0A patent/CN115916789B/zh active Active
- 2021-05-21 US US17/326,383 patent/US11976082B2/en active Active
- 2021-05-21 TW TW110118394A patent/TW202208378A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20210363157A1 (en) | 2021-11-25 |
| WO2021233884A1 (en) | 2021-11-25 |
| TW202208378A (zh) | 2022-03-01 |
| ES2991340T3 (es) | 2024-12-03 |
| EP4153600A1 (en) | 2023-03-29 |
| JP2023526353A (ja) | 2023-06-21 |
| HUE069479T2 (hu) | 2025-04-28 |
| DK4153600T3 (da) | 2024-10-21 |
| EP4153600B1 (en) | 2024-08-07 |
| JP7702969B2 (ja) | 2025-07-04 |
| CN115916789A (zh) | 2023-04-04 |
| US11976082B2 (en) | 2024-05-07 |
| CN115916789B (zh) | 2025-06-27 |
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