JP2010522242A5 - - Google Patents
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- Publication number
- JP2010522242A5 JP2010522242A5 JP2010501112A JP2010501112A JP2010522242A5 JP 2010522242 A5 JP2010522242 A5 JP 2010522242A5 JP 2010501112 A JP2010501112 A JP 2010501112A JP 2010501112 A JP2010501112 A JP 2010501112A JP 2010522242 A5 JP2010522242 A5 JP 2010522242A5
- Authority
- JP
- Japan
- Prior art keywords
- disease
- tachyarrhythmia
- crohn
- pain
- bowel syndrome
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010011401 Crohn's disease Diseases 0.000 claims 4
- 208000002551 Irritable Bowel Syndrome Diseases 0.000 claims 4
- 208000002193 Pain Diseases 0.000 claims 4
- 206010049447 Tachyarrhythmia Diseases 0.000 claims 4
- 150000001875 compounds Chemical class 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 4
- 102000018674 Sodium Channels Human genes 0.000 claims 1
- 108010052164 Sodium Channels Proteins 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000000051 modifying Effects 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 239000012453 solvate Substances 0.000 claims 1
Claims (4)
- ナトリウムチャネル調節物質が指示される疾病又は症状、好ましくは疼痛、過敏性腸症候群、クローン病及び頻脈性不整脈の治療のための医薬の製造における、請求項１から７５のいずれか１項に記載の化合物の使用。
- 疼痛、過敏性腸症候群、クローン病及び頻脈性不整脈の治療において使用するための、請求項１から７５のいずれか１項に記載の化合物。
- 疼痛、過敏性腸症候群、クローン病及び頻脈性不整脈の治療のための医薬の調製における、請求項１から７５のいずれか１項に記載の化合物、又は医薬的に受容可能な塩或いはこれらの溶媒和物の使用。
- 疼痛、過敏性腸症候群、クローン病及び頻脈性不整脈から選択される症状の治療剤であって、前記症状を寛解又は緩和するために十分な量の、請求項１から７５のいずれか１項に記載の化合物を含む、前記治療剤。
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89673507P | 2007-03-23 | 2007-03-23 | |
| US60/896,735 | 2007-03-23 | ||
| US3532408P | 2008-03-10 | 2008-03-10 | |
| US61/035,324 | 2008-03-10 | ||
| PCT/US2008/057730 WO2008118758A1 (en) | 2007-03-23 | 2008-03-20 | Inhibitors of ion channels |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010522242A JP2010522242A (ja) | 2010-07-01 |
| JP2010522242A5 true JP2010522242A5 (ja) | 2011-04-21 |
| JP5361857B2 JP5361857B2 (ja) | 2013-12-04 |
Family
ID=39788940
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010501112A Expired - Fee Related JP5361857B2 (ja) | 2007-03-23 | 2008-03-20 | イオンチャネルの阻害剤 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US8357711B2 (ja) |
| EP (1) | EP1995241B1 (ja) |
| JP (1) | JP5361857B2 (ja) |
| AR (1) | AR065824A1 (ja) |
| AT (1) | ATE461177T1 (ja) |
| CA (1) | CA2681572C (ja) |
| CL (1) | CL2008000835A1 (ja) |
| DE (1) | DE602008000809D1 (ja) |
| ES (1) | ES2340640T3 (ja) |
| PA (1) | PA8773501A1 (ja) |
| PE (1) | PE20090237A1 (ja) |
| TW (1) | TW200845969A (ja) |
| UY (1) | UY30978A1 (ja) |
| WO (1) | WO2008118758A1 (ja) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7120549B2 (ja) | 2016-12-15 | 2022-08-17 | 小野薬品工業株式会社 | Ｔｒｅｋ（ｔｗｉｋ関連ｋチャネル）チャネルのアクチベータ |
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| JP2007501804A (ja) | 2003-08-08 | 2007-02-01 | バーテックス ファーマシューティカルズ インコーポレイテッド | 電位開口型のナトリウムチャネルのインヒビターとして有用な組成物 |
| US20070191336A1 (en) | 2003-12-24 | 2007-08-16 | Flynn Daniel L | Anti-inflammatory medicaments |
| US20080015223A1 (en) | 2004-12-03 | 2008-01-17 | Arena Pharmaceuticals, Inc. | Pyrazole Derivatives as Modulators of the 5-Ht2a Serotonin Receptor Useful for the Treatment of Disorders Related Thereto |
| GB0510139D0 (en) | 2005-05-18 | 2005-06-22 | Addex Pharmaceuticals Sa | Novel compounds B1 |
| GB0513702D0 (en) | 2005-07-04 | 2005-08-10 | Sterix Ltd | Compound |
| US7754717B2 (en) | 2005-08-15 | 2010-07-13 | Amgen Inc. | Bis-aryl amide compounds and methods of use |
| WO2007055941A2 (en) | 2005-11-03 | 2007-05-18 | Merck & Co., Inc. | Histone deacetylase inhibitors with aryl-pyrazolyl motifs |
| BRPI0709949A2 (pt) | 2006-04-12 | 2011-08-30 | Wyeth Corp | composto de fórmula iii; método de inibir atividade quinase em uma célula; método de inibir atividade quinase em um mamìfero; composição farmacêutica; método de tratar uma condição dependente de quinase; método de tratar uma doença associada com ativação de nf-kb; método de tratar proliferação de célula tumoral, crescimento de célula tumoral, ou tumorigênese; método de reduzir inflamação; método de tratar uma condição inflamatória ou autoimune; método de tratar uma condição cardiovascular, metabólica ou isquêmica; método de tratar uma doença infecciosa; método de tratar uma condição pré ou pós menopausa; e método de tratar osteoporose |
-
2008
- 2008-03-20 DE DE602008000809T patent/DE602008000809D1/de active Active
- 2008-03-20 ES ES08153165T patent/ES2340640T3/es active Active
- 2008-03-20 CL CL200800835A patent/CL2008000835A1/es unknown
- 2008-03-20 JP JP2010501112A patent/JP5361857B2/ja not_active Expired - Fee Related
- 2008-03-20 AT AT08153165T patent/ATE461177T1/de not_active IP Right Cessation
- 2008-03-20 WO PCT/US2008/057730 patent/WO2008118758A1/en active Application Filing
- 2008-03-20 EP EP08153165A patent/EP1995241B1/en active Active
- 2008-03-20 US US12/052,593 patent/US8357711B2/en not_active Expired - Fee Related
- 2008-03-20 CA CA2681572A patent/CA2681572C/en not_active Expired - Fee Related
- 2008-03-21 TW TW097110261A patent/TW200845969A/zh unknown
- 2008-03-24 PE PE2008000533A patent/PE20090237A1/es not_active Application Discontinuation
- 2008-03-24 UY UY30978A patent/UY30978A1/es not_active Application Discontinuation
- 2008-03-24 PA PA20088773501A patent/PA8773501A1/es unknown
- 2008-03-25 AR ARP080101215A patent/AR065824A1/es not_active Application Discontinuation
-
2012
- 2012-11-15 US US13/677,849 patent/US8741934B2/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7120549B2 (ja) | 2016-12-15 | 2022-08-17 | 小野薬品工業株式会社 | Ｔｒｅｋ（ｔｗｉｋ関連ｋチャネル）チャネルのアクチベータ |
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