JP2019089796A5 - - Google Patents
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- JP2019089796A5 JP2019089796A5 JP2019009896A JP2019009896A JP2019089796A5 JP 2019089796 A5 JP2019089796 A5 JP 2019089796A5 JP 2019009896 A JP2019009896 A JP 2019009896A JP 2019009896 A JP2019009896 A JP 2019009896A JP 2019089796 A5 JP2019089796 A5 JP 2019089796A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- receptor antagonist
- kit
- dosage form
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000008194 pharmaceutical composition Substances 0.000 claims 12
- 239000000938 histamine H1 antagonist Substances 0.000 claims 5
- 229960001803 cetirizine Drugs 0.000 claims 4
- ZKLPARSLTMPFCP-UHFFFAOYSA-N levocetirizine Chemical compound C1CN(CCOCC(=O)O)CCN1C(C=1C=CC(Cl)=CC=1)C1=CC=CC=C1 ZKLPARSLTMPFCP-UHFFFAOYSA-N 0.000 claims 4
- 239000006186 oral dosage form Substances 0.000 claims 4
- 239000003485 histamine H2 receptor antagonist Substances 0.000 claims 3
- ZKLPARSLTMPFCP-OAQYLSRUSA-N 2-[2-[4-[(R)-(4-chlorophenyl)-phenylmethyl]piperazin-1-ium-1-yl]ethoxy]acetate Chemical compound C1CN(CCOCC(=O)O)CCN1[C@@H](C=1C=CC(Cl)=CC=1)C1=CC=CC=C1 ZKLPARSLTMPFCP-OAQYLSRUSA-N 0.000 claims 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N D-Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 2
- 206010012735 Diarrhoea Diseases 0.000 claims 2
- XUFQPHANEAPEMJ-UHFFFAOYSA-N Famotidine Chemical compound NC(N)=NC1=NC(CSCCC(N)=NS(N)(=O)=O)=CS1 XUFQPHANEAPEMJ-UHFFFAOYSA-N 0.000 claims 2
- 229960001596 Famotidine Drugs 0.000 claims 2
- 239000002552 dosage form Substances 0.000 claims 2
- 239000008103 glucose Substances 0.000 claims 2
- 229960001508 levocetirizine Drugs 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 208000004232 Enteritis Diseases 0.000 claims 1
- 210000000138 Mast Cells Anatomy 0.000 claims 1
- 201000009840 acute diarrhea Diseases 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 150000001720 carbohydrates Chemical class 0.000 claims 1
- 201000008286 diarrhea Diseases 0.000 claims 1
- KEAYESYHFKHZAL-UHFFFAOYSA-N sodium Chemical compound [Na] KEAYESYHFKHZAL-UHFFFAOYSA-N 0.000 claims 1
- 229910052708 sodium Inorganic materials 0.000 claims 1
- 239000011734 sodium Substances 0.000 claims 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N β-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims 1
Claims (12)
- H1受容体アンタゴニスト及びH2受容体アンタゴニストを含むキットであって、
前記H1受容体アンタゴニストが、セチリジン、レボセチリジン、又はそれらの混合物を含む、キット。 - 医薬組成物であって、
H1受容体アンタゴニスト及びH2受容体アンタゴニストを含み、
前記H1受容体アンタゴニストが、セチリジン、レボセチリジン、又はそれらの混合物を含む、医薬組成物。 - 患者において下痢を治療するのに使用するための、請求項1に記載のキット又は請求項2に記載の医薬組成物。
- 前記患者が、肥満細胞性腸炎に罹患していない、請求項3に記載のキット又は請求項3に記載の医薬組成物。
- 前記患者が、急性下痢に罹患している、請求項3若しくは4に記載のキット又は請求項3若しくは4に記載の医薬組成物。
- 前記H1受容体アンタゴニスト及び前記H2受容体アンタゴニストが、同時に投与される、請求項1及び3〜5のいずれか一項に記載のキット又は請求項2〜5のいずれか一項に記載の医薬組成物。
- セチリジンが、5〜20mgの量で投与され、及び/又は、ファモチジンが、10〜40mgの量で投与される、請求項1及び3〜6のいずれか一項に記載のキット又は請求項2〜6のいずれか一項に記載の医薬組成物。
- ファモチジン及びセチリジンが、単位剤形として一緒に投与される、請求項1及び3〜7のいずれか一項に記載のキット又は請求項2〜7のいずれか一項に記載の医薬組成物。
- 経口剤形である、請求項2〜8のいずれか一項に記載の医薬組成物。
- 前記経口剤形が、複数の単位剤形を含む、請求項9に記載の医薬組成物。
- 前記経口剤形が、ナトリウム、及び、グルコース又はグルコース含有サッカリドをさらに含む、請求項9又は10に記載の医薬組成物。
- 前記経口剤形が、経口補水溶液をさらに含む、請求項9〜11のいずれか一項に記載の医薬組成物。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361782608P | 2013-03-14 | 2013-03-14 | |
US61/782,608 | 2013-03-14 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2018054088A Division JP6473254B2 (ja) | 2013-03-14 | 2018-03-22 | 下痢を治療するための製品及び方法 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2020184294A Division JP2021046400A (ja) | 2013-03-14 | 2020-11-04 | 下痢を治療するための製品及び方法 |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2019089796A JP2019089796A (ja) | 2019-06-13 |
JP2019089796A5 true JP2019089796A5 (ja) | 2019-10-24 |
JP6790140B2 JP6790140B2 (ja) | 2020-11-25 |
Family
ID=50680150
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2016502404A Active JP6313417B2 (ja) | 2013-03-14 | 2014-03-14 | 下痢を治療するための製品及び方法 |
JP2018054088A Active JP6473254B2 (ja) | 2013-03-14 | 2018-03-22 | 下痢を治療するための製品及び方法 |
JP2019009896A Active JP6790140B2 (ja) | 2013-03-14 | 2019-01-24 | 下痢を治療するための製品及び方法 |
JP2020184294A Pending JP2021046400A (ja) | 2013-03-14 | 2020-11-04 | 下痢を治療するための製品及び方法 |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2016502404A Active JP6313417B2 (ja) | 2013-03-14 | 2014-03-14 | 下痢を治療するための製品及び方法 |
JP2018054088A Active JP6473254B2 (ja) | 2013-03-14 | 2018-03-22 | 下痢を治療するための製品及び方法 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2020184294A Pending JP2021046400A (ja) | 2013-03-14 | 2020-11-04 | 下痢を治療するための製品及び方法 |
Country Status (20)
Country | Link |
---|---|
US (4) | US9717726B2 (ja) |
EP (3) | EP3581205A3 (ja) |
JP (4) | JP6313417B2 (ja) |
KR (4) | KR102449977B1 (ja) |
CN (2) | CN108939076A (ja) |
AU (3) | AU2014239878B2 (ja) |
BR (2) | BR122017004716A2 (ja) |
CA (1) | CA2906005C (ja) |
DK (1) | DK2968205T3 (ja) |
ES (2) | ES2655505T3 (ja) |
HK (2) | HK1213205A1 (ja) |
HU (1) | HUE035201T2 (ja) |
IL (3) | IL273377B2 (ja) |
MX (2) | MX366329B (ja) |
MY (1) | MY175326A (ja) |
PL (1) | PL2968205T3 (ja) |
PT (1) | PT2968205T (ja) |
RU (1) | RU2015143475A (ja) |
WO (1) | WO2014152420A2 (ja) |
ZA (1) | ZA201708539B (ja) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9717726B2 (en) * | 2013-03-14 | 2017-08-01 | Maregade Rx, LLC | Product and method for treating diarrhea |
WO2015073573A1 (en) * | 2013-11-14 | 2015-05-21 | Jacobs Michael M | Compositions and methods for the prevention and treatment of alcohol-induced hangover syndrome |
ES2953520T3 (es) | 2016-12-23 | 2023-11-14 | Maregade Rx Llc | Producto a baja dosis y método para el tratamiento de la diarrea |
IT201900012645A1 (it) * | 2019-07-23 | 2021-01-23 | Eros Zanotti | Una composizione farmaceutica per l'uso nel trattamento delle chinetosi |
US11424105B2 (en) * | 2019-08-05 | 2022-08-23 | Hitachi High-Tech Corporation | Plasma processing apparatus |
WO2023049205A1 (en) * | 2021-09-22 | 2023-03-30 | Hista Rx Llc | Compositions and methods for treating and preventing interstitial cystitis |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5204118A (en) | 1989-11-02 | 1993-04-20 | Mcneil-Ppc, Inc. | Pharmaceutical compositions and methods for treating the symptoms of overindulgence |
WO1995001792A1 (en) | 1993-07-06 | 1995-01-19 | Merck & Co., Inc. | H2 antagonist-antihistamine combinations |
US6264984B1 (en) * | 1999-12-06 | 2001-07-24 | Bristol-Myers Squibb Company | Effervescent histamine H2 antagonist composition |
US6656492B2 (en) * | 2000-06-30 | 2003-12-02 | Yamanouchi Pharmaceutical Co., Ltd. | Quick disintegrating tablet in buccal cavity and manufacturing method thereof |
CN1294253C (zh) | 2000-11-30 | 2007-01-10 | 生物平衡公司 | 细菌菌株,加工过的植物提取物,含有它们的组合物,其制备方法及其治疗和工业应用 |
NZ550723A (en) * | 2001-11-23 | 2008-06-30 | Janssen Pharmaceutica Nv | The use of anti-histaminics for acute reduction of elevated intracranial pressure |
SE528789C2 (sv) | 2004-09-10 | 2007-02-13 | Sandvik Intellectual Property | PVD-belagt skär av hårdmetall samt sätt att tillverka detta |
US20070077300A1 (en) * | 2005-09-30 | 2007-04-05 | Wynn David W | Oral compositions containing a salivation inducing agent |
US20090312358A1 (en) | 2006-03-22 | 2009-12-17 | Trustees Of Boston University | Method for management of diarrhea |
US8207188B2 (en) | 2006-04-07 | 2012-06-26 | Michalis Nicolaou | Treatment of diseases modulated by a H4 receptor agonist |
US20070254050A1 (en) * | 2006-05-01 | 2007-11-01 | Quart Barry D | Method for treatment of diarrhea-predominant irritable bowel syndrome |
US20090042972A1 (en) * | 2006-05-19 | 2009-02-12 | Somaxon Pharmaceuticals, Inc. | Methods of using low-dose doxepin for the improvement of sleep |
EP2559434A3 (en) | 2007-02-12 | 2013-05-29 | Mike Nicolaou | Treatment of COPD using a histidine decarboxylase inhibitor sole or combined with an anti-H1 drug or with a leucotriene receptor antagonist |
US20090074862A1 (en) * | 2007-04-13 | 2009-03-19 | Luigi Schioppi | Low-dose doxepin formulations and methods of making and using the same |
US8263581B2 (en) | 2009-07-03 | 2012-09-11 | Jdp Therapeutics, Inc. | Non-sedating antihistamine injection formulations and methods of use thereof |
US9856477B2 (en) | 2012-11-13 | 2018-01-02 | Codiak Biosciences, Inc. | Delivery of therapeutic agent |
US9717726B2 (en) | 2013-03-14 | 2017-08-01 | Maregade Rx, LLC | Product and method for treating diarrhea |
ES2953520T3 (es) | 2016-12-23 | 2023-11-14 | Maregade Rx Llc | Producto a baja dosis y método para el tratamiento de la diarrea |
-
2014
- 2014-03-13 US US14/209,937 patent/US9717726B2/en active Active
- 2014-03-14 EP EP19169633.5A patent/EP3581205A3/en active Pending
- 2014-03-14 CN CN201810755897.7A patent/CN108939076A/zh active Pending
- 2014-03-14 MY MYPI2015703092A patent/MY175326A/en unknown
- 2014-03-14 CA CA2906005A patent/CA2906005C/en active Active
- 2014-03-14 PT PT147224455T patent/PT2968205T/pt unknown
- 2014-03-14 PL PL14722445T patent/PL2968205T3/pl unknown
- 2014-03-14 EP EP17189072.6A patent/EP3269364B1/en active Active
- 2014-03-14 BR BR122017004716-7A patent/BR122017004716A2/pt not_active Application Discontinuation
- 2014-03-14 EP EP14722445.5A patent/EP2968205B1/en active Active
- 2014-03-14 ES ES14722445.5T patent/ES2655505T3/es active Active
- 2014-03-14 MX MX2017011532A patent/MX366329B/es unknown
- 2014-03-14 JP JP2016502404A patent/JP6313417B2/ja active Active
- 2014-03-14 KR KR1020217004881A patent/KR102449977B1/ko active IP Right Grant
- 2014-03-14 ES ES17189072T patent/ES2743604T3/es active Active
- 2014-03-14 IL IL273377A patent/IL273377B2/en unknown
- 2014-03-14 HU HUE14722445A patent/HUE035201T2/hu unknown
- 2014-03-14 WO PCT/US2014/027323 patent/WO2014152420A2/en active Application Filing
- 2014-03-14 BR BR112015022513A patent/BR112015022513A2/pt not_active Application Discontinuation
- 2014-03-14 KR KR1020207023569A patent/KR20200100211A/ko not_active Application Discontinuation
- 2014-03-14 KR KR1020157029028A patent/KR101884506B1/ko active IP Right Grant
- 2014-03-14 KR KR1020187021688A patent/KR20180088514A/ko not_active IP Right Cessation
- 2014-03-14 RU RU2015143475A patent/RU2015143475A/ru not_active Application Discontinuation
- 2014-03-14 DK DK14722445.5T patent/DK2968205T3/da active
- 2014-03-14 CN CN201480022471.0A patent/CN105324112B/zh active Active
- 2014-03-14 AU AU2014239878A patent/AU2014239878B2/en active Active
- 2014-03-14 MX MX2015011885A patent/MX350814B/es active IP Right Grant
-
2015
- 2015-09-09 IL IL241372A patent/IL241372B/en active IP Right Grant
-
2016
- 2016-02-04 HK HK16101359.5A patent/HK1213205A1/zh unknown
- 2016-09-06 US US15/257,674 patent/US10034875B2/en active Active
-
2017
- 2017-10-24 AU AU2017251701A patent/AU2017251701B2/en active Active
- 2017-12-13 IL IL256300A patent/IL256300B/en active IP Right Grant
- 2017-12-15 ZA ZA2017/08539A patent/ZA201708539B/en unknown
-
2018
- 2018-03-22 JP JP2018054088A patent/JP6473254B2/ja active Active
- 2018-05-28 HK HK18106976.5A patent/HK1247557B/zh unknown
- 2018-07-06 US US16/029,384 patent/US11058681B2/en active Active
-
2019
- 2019-01-24 JP JP2019009896A patent/JP6790140B2/ja active Active
- 2019-02-28 AU AU2019201412A patent/AU2019201412A1/en not_active Abandoned
-
2020
- 2020-11-04 JP JP2020184294A patent/JP2021046400A/ja active Pending
-
2021
- 2021-05-28 US US17/333,525 patent/US20220047583A1/en active Pending
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