JP2010519505A - 紫外線検出に適したポリマーデバイス - Google Patents
紫外線検出に適したポリマーデバイス Download PDFInfo
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- JP2010519505A JP2010519505A JP2009549377A JP2009549377A JP2010519505A JP 2010519505 A JP2010519505 A JP 2010519505A JP 2009549377 A JP2009549377 A JP 2009549377A JP 2009549377 A JP2009549377 A JP 2009549377A JP 2010519505 A JP2010519505 A JP 2010519505A
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- 238000000825 ultraviolet detection Methods 0.000 title description 12
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- WKBPZYKAUNRMKP-UHFFFAOYSA-N 1-[2-(2,4-dichlorophenyl)pentyl]1,2,4-triazole Chemical compound C=1C=C(Cl)C=C(Cl)C=1C(CCC)CN1C=NC=N1 WKBPZYKAUNRMKP-UHFFFAOYSA-N 0.000 description 1
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- 102000039446 nucleic acids Human genes 0.000 description 1
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- 230000035699 permeability Effects 0.000 description 1
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- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 229920003031 santoprene Polymers 0.000 description 1
- 229920001169 thermoplastic Polymers 0.000 description 1
- 239000004416 thermosoftening plastic Substances 0.000 description 1
- 239000012780 transparent material Substances 0.000 description 1
- 238000009281 ultraviolet germicidal irradiation Methods 0.000 description 1
- 229910052724 xenon Inorganic materials 0.000 description 1
- FHNFHKCVQCLJFQ-UHFFFAOYSA-N xenon atom Chemical compound [Xe] FHNFHKCVQCLJFQ-UHFFFAOYSA-N 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/33—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using ultraviolet light
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/08—Radiation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/08—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor
- B01J19/081—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor employing particle radiation or gamma-radiation
- B01J19/082—Gamma-radiation only
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/05—Flow-through cuvettes
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/59—Transmissivity
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N30/74—Optical detectors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/10—Apparatus features
- A61L2202/11—Apparatus for generating biocidal substances, e.g. vaporisers, UV lamps
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
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- G01N2021/0346—Capillary cells; Microcells
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
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- Life Sciences & Earth Sciences (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
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- Veterinary Medicine (AREA)
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- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Optical Measuring Cells (AREA)
Abstract
【選択図】図2
Description
12 室
14、32 壁
16 入口
18 出口
20’、20”、22’、22” 壁
30 密封手段
31 密封型フローセル
34 入口部分
36 出口部分
38 室
32、40’、40”、42’、42” 壁
44 UV放射透過窓
46 リム
50、52 液体流れチャネル
54、56 ホルダー
H 光路長、2つの壁の内面間の距離
L フローセルの長さ
Claims (18)
- 少なくとも1つのUV透過窓(22’)を備えている試料貫流室(12)によって分離された流体入口(16)と流体出口(18)を備えているフローセル(10)において、
前記少なくとも1つのUV透過窓(22’)は、ポリマー材料で作られていて、既にガンマ線照射滅菌を施されていることを特徴とする、フローセル(10)。 - 前記ガンマ線放射滅菌には少なくとも10kGyの線量が使用されていることを特徴とする、請求項1に記載のフローセル。
- 前記ポリマー材料は、ガンマ線照射滅菌を施した後に、280nmの波長でmm当たり1%から40%の間の範囲のUV透過率を有していることを特徴とする、請求項1又は2の何れかに記載のフローセル。
- ガンマ線照射滅菌を施した後の前記ポリマー材料の前記透過率は、約0.6μW/mm2の強度のUV光に72時間曝されている間に10%を越えては変動しないことを特徴とする、請求項1から3の何れか一項に記載のフローセル。
- ガンマ線照射滅菌を施した後の前記ポリマー材料の前記透過率は、約0.6μW/mm2の強度のUV光に48時間曝されている間に10%を越えては変動しないことを特徴とする、請求項1から3の何れか一項に記載のフローセル。
- 前記ポリマー材料の前記UV透過率は、ガンマ線照射滅菌を施した後では、mm当たり2%を越え30%未満であることを特徴とする、請求項1から5の何れか一項に記載のフローセル。
- 前記ポリマー材料の前記UV透過率は、ガンマ線照射滅菌を施した後では、mm当たり5%を越え20%未満であることを特徴とする、請求項1から6の何れか一項に記載のフローセル。
- 前記ポリマー材料の前記UV透過率は、ガンマ線照射滅菌を施した後では、mm当たり12%を越え18%未満であることを特徴とする、請求項1から7の何れか一項に記載のフローセル。
- 前記フローセルの外側に密封手段(30)を装着し、密封式フローセル(31)を提供していることを特徴とする、請求項1から8の何れか一項に記載のフローセル。
- 前記密封手段は、基本的には、UV放射、可視光放射、又は近赤外線放射が何れも材料を通過することができないように、不透明な材料で作られており、前記密封手段は、付加的にUV放射透過窓(44)を備えていることを特徴とする、請求項9に記載のフローセル。
- 可燃性であることを特徴とする、請求項1から10の何れか一項に記載のフローセル。
- 請求項1から11の何れか一項に記載のフローセルを製造するための方法において、前記フローセルはモールド成形法で作られることを特徴とする、方法。
- 請求項1から11の何れか一項に記載のフローセルを製造するための方法において、前記フローセルは射出成形法で作られることを特徴とする、方法。
- 請求項1から11の何れか一項に記載のフローセルを製造するための方法において、前記フローセルは押出成形法で作られることを特徴とする、方法。
- 請求項1から11の何れか一項に記載のフローセルを製造するための方法において、前記フローセルは同時押出成形法で作られることを特徴とする、方法。
- 請求項1から11の何れか一項に記載のフローセルを使用した、試料のUV吸収量を測定するための方法。
- 前記UV放射は1つ又はそれ以上の発光ダイオードによって提供されることを特徴とする、請求項16に記載の方法。
- 請求項1から11の何れかに記載のフローセルと、片側が開いているUV吸収量検出器と、を備えている部品一式。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0703175.0 | 2007-02-20 | ||
GBGB0703175.0A GB0703175D0 (en) | 2007-02-20 | 2007-02-20 | Polymeric device suitable for ultraviolet detection |
PCT/EP2008/001168 WO2008101637A2 (en) | 2007-02-20 | 2008-02-15 | Polymeric device suitable for ultraviolet detection |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2010519505A true JP2010519505A (ja) | 2010-06-03 |
JP5180973B2 JP5180973B2 (ja) | 2013-04-10 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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JP2009549377A Active JP5180973B2 (ja) | 2007-02-20 | 2008-02-15 | 紫外線検出に適したポリマーデバイス |
Country Status (7)
Country | Link |
---|---|
US (4) | US20080212073A1 (ja) |
EP (1) | EP2113076B1 (ja) |
JP (1) | JP5180973B2 (ja) |
CN (1) | CN101611305B (ja) |
CA (1) | CA2676204A1 (ja) |
GB (2) | GB0703175D0 (ja) |
WO (1) | WO2008101637A2 (ja) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9575087B2 (en) | 2012-09-06 | 2017-02-21 | Parker-Hannifin Corporation | Risk-managed, single-use, pre-calibrated, pre-sterilized sensors for use in bio-processing applications |
US11827875B2 (en) | 2006-08-02 | 2023-11-28 | Finesse Solutions, Inc. | Method for manufacturing a composite sensor |
US10227555B2 (en) | 2006-08-02 | 2019-03-12 | Finesse Solutions, Inc. | Composite sensor assemblies for single use bioreactors |
GB0703175D0 (en) | 2007-02-20 | 2007-03-28 | Ge Healthcare Bio Sciences Ab | Polymeric device suitable for ultraviolet detection |
GB0922426D0 (en) * | 2009-12-22 | 2010-02-03 | Ge Healthcare Bio Sciences Ab | Containers for chromatography media |
DE102010038428A1 (de) * | 2010-07-26 | 2012-01-26 | Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG | Optisches Messsystem |
US20120119101A1 (en) * | 2010-11-12 | 2012-05-17 | Endress + Hauser Conducta Gesellschaft Fur Mess-Und Regeltechnik Mbh + Co. Kg | Miniature UV sensor utilizing a disposable flow cell |
DE102011013001B4 (de) * | 2011-03-04 | 2016-05-25 | Optek-Danulat Gmbh | Durchströmbare Messzelle zur Aufnahme von Messmitteln |
US8817259B2 (en) | 2011-03-25 | 2014-08-26 | Parker-Hannifin Corporation | Optical sensors for monitoring biopharmaceutical solutions in single-use containers |
WO2013099229A2 (en) | 2011-12-30 | 2013-07-04 | Makita Corporation | Battery system for a power tool, as well as battery holder therefor, charger, and charging system |
US9146192B2 (en) * | 2012-05-17 | 2015-09-29 | Wyatt Technology Corporation | Integrated light scattering and ultraviolet absorption measurement system |
US20140011980A1 (en) * | 2012-07-03 | 2014-01-09 | Allergan, Inc. | Methods for sterilizing compositions and resulting compositions |
DE102012108158B4 (de) * | 2012-09-03 | 2016-03-17 | Johann Wolfgang Goethe-Universität | Kapillarzelle, Anordnung und Verfahren zur Aufnahme, zur Positionierung und zur Untersuchung einer mikroskopischen Probe |
US9781496B2 (en) | 2012-10-25 | 2017-10-03 | Milwaukee Electric Tool Corporation | Worksite audio device with wireless interface |
WO2018114755A1 (en) * | 2016-12-20 | 2018-06-28 | General Electric Company | Coriolis flow meter for measuring properties of a fluid and method therefor |
US10119851B2 (en) | 2016-12-20 | 2018-11-06 | General Electric Company | Coriolis flow meter for measuring properties of a fluid and method therefor |
CN110346461B (zh) * | 2018-04-03 | 2022-01-11 | 中国科学院大连化学物理研究所 | 一种光检测流通池 |
JP7390135B2 (ja) | 2019-08-30 | 2023-12-01 | 株式会社日立産機システム | 電力変換装置 |
DE102019132218B4 (de) * | 2019-11-27 | 2023-06-15 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Durchflussmesszelle |
Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63315054A (ja) * | 1987-06-17 | 1988-12-22 | Takeshi Suzuki | 小児鍼 |
JPH03127799A (ja) * | 1989-10-13 | 1991-05-30 | Kuraray Co Ltd | ペプチドおよびその用途 |
JPH0477540A (ja) * | 1990-07-17 | 1992-03-11 | Idemitsu Petrochem Co Ltd | ポリプロピレン系樹脂組成物 |
JPH09220214A (ja) * | 1996-02-20 | 1997-08-26 | Sekisui Chem Co Ltd | 細胞機能測定用反応器及び細胞機能測定用キット |
JPH1038795A (ja) * | 1996-07-27 | 1998-02-13 | Horiba Ltd | 光学式流体分析装置 |
JP2000214083A (ja) * | 1997-05-20 | 2000-08-04 | Zymequest Inc | 光学式センサ |
JP2003523236A (ja) * | 2000-02-08 | 2003-08-05 | ジェンデル・リミテッド | 装 置 |
JP2004037409A (ja) * | 2002-07-08 | 2004-02-05 | Toagosei Co Ltd | 光吸収スペクトル分析用セル、及びそれを用いるシラノール基濃度の測定方法 |
JP2004219409A (ja) * | 2002-12-20 | 2004-08-05 | Lifescan Inc | 滅菌され、較正されたバイオセンサーベースの医療デバイスの製造方法 |
JP2004354285A (ja) * | 2003-05-30 | 2004-12-16 | Shimamuratekku:Kk | 分取液体クロマトグラフィー用検出装置 |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3401591A (en) * | 1963-12-09 | 1968-09-17 | Warner Lambert Pharmaceutical | Analytical cuvette and supply system wherein the cuvette inlet and outlet are located on the bottom of the cuvette |
US3327119A (en) * | 1964-03-26 | 1967-06-20 | Ibm | Method and apparatus for detecting cancer cells |
US4008397A (en) * | 1975-04-24 | 1977-02-15 | Hoffmann-La Roche Inc. | Fluorometer flow cell |
JPS63233374A (ja) * | 1987-03-20 | 1988-09-29 | Tohoku Denshi Sangyo Kk | 過酸化脂質の測定方法およびその測定装置 |
US5444807A (en) * | 1993-03-29 | 1995-08-22 | World Precision Instruments, Inc. | Micro chemical analysis employing flow through detectors |
US6199257B1 (en) * | 1995-02-28 | 2001-03-13 | Thermo Separation Products, Inc. | Method of making a flow cell for light absorption measurement of small volume samples |
US5674290A (en) * | 1995-04-05 | 1997-10-07 | Li; Shu-Tung | Water-stabilized biopolymeric implants |
US5885470A (en) * | 1997-04-14 | 1999-03-23 | Caliper Technologies Corporation | Controlled fluid transport in microfabricated polymeric substrates |
US6130981A (en) | 1998-03-20 | 2000-10-10 | Polymicro Technologies, Llc | Gamma radiation sterilized fiber optic UV delivery systems |
RU2145898C1 (ru) * | 1998-07-07 | 2000-02-27 | Иващенко Гаррий Дмитриевич | Устройство для экстракорпоральной обработки крови |
US7068361B2 (en) * | 1999-06-03 | 2006-06-27 | Baxter International | Apparatus, systems and methods for processing and treating a biological fluid with light |
JP4605734B2 (ja) * | 1999-06-21 | 2011-01-05 | ザ ジェネラル ホスピタル コーポレイション | 臓器補助装置のための細胞培養システム及び方法 |
US6495351B2 (en) * | 2000-02-08 | 2002-12-17 | Gendel Limited | Loading system and method for using the same |
CA2399452A1 (en) * | 2000-02-11 | 2001-08-16 | Proteosys Ag. | Use of neuregulin-.beta. as an indicator and/or target |
US7150815B2 (en) | 2000-10-05 | 2006-12-19 | E. I. Du Pont De Nemours And Company | Polymeric microfabricated fluidic device suitable for ultraviolet detection |
WO2002075284A2 (en) * | 2001-03-20 | 2002-09-26 | Abb Bomem Inc. | Flow-through cell |
US20040142484A1 (en) * | 2002-09-30 | 2004-07-22 | Intel Corporation | Spectroscopic analysis system and method |
JP4236995B2 (ja) * | 2003-06-17 | 2009-03-11 | 三井化学株式会社 | ポリプロピレン樹脂組成物およびその用途 |
JP4679847B2 (ja) * | 2004-07-12 | 2011-05-11 | オリンパス株式会社 | 細胞の解析方法 |
US20060182664A1 (en) | 2005-02-14 | 2006-08-17 | Peck Bill J | Flow cell devices, systems and methods of using the same |
US7277167B2 (en) * | 2005-09-13 | 2007-10-02 | Agilent Technologies, Inc. | Modular cuvettes and methods for use thereof |
US20070081159A1 (en) * | 2005-10-11 | 2007-04-12 | Giffin Kristin M | Apparatus and methods for evaluating an optical property of a liquid sample |
US7515259B2 (en) * | 2006-03-10 | 2009-04-07 | Dionex Corporation | Flow cell for optical detector and method of forming same |
GB0703175D0 (en) | 2007-02-20 | 2007-03-28 | Ge Healthcare Bio Sciences Ab | Polymeric device suitable for ultraviolet detection |
-
2007
- 2007-02-20 GB GBGB0703175.0A patent/GB0703175D0/en not_active Ceased
-
2008
- 2008-02-15 CA CA002676204A patent/CA2676204A1/en not_active Abandoned
- 2008-02-15 WO PCT/EP2008/001168 patent/WO2008101637A2/en active Application Filing
- 2008-02-15 GB GB0802836A patent/GB2446934A/en not_active Withdrawn
- 2008-02-15 CN CN2008800048959A patent/CN101611305B/zh active Active
- 2008-02-15 JP JP2009549377A patent/JP5180973B2/ja active Active
- 2008-02-15 US US12/032,197 patent/US20080212073A1/en not_active Abandoned
- 2008-02-15 EP EP08715789.7A patent/EP2113076B1/en active Active
-
2013
- 2013-05-10 US US13/891,340 patent/US9404862B2/en active Active
-
2016
- 2016-07-01 US US15/200,722 patent/US10094770B2/en active Active
-
2018
- 2018-09-13 US US16/130,100 patent/US10816459B2/en active Active
Patent Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63315054A (ja) * | 1987-06-17 | 1988-12-22 | Takeshi Suzuki | 小児鍼 |
JPH03127799A (ja) * | 1989-10-13 | 1991-05-30 | Kuraray Co Ltd | ペプチドおよびその用途 |
JPH0477540A (ja) * | 1990-07-17 | 1992-03-11 | Idemitsu Petrochem Co Ltd | ポリプロピレン系樹脂組成物 |
JPH09220214A (ja) * | 1996-02-20 | 1997-08-26 | Sekisui Chem Co Ltd | 細胞機能測定用反応器及び細胞機能測定用キット |
JPH1038795A (ja) * | 1996-07-27 | 1998-02-13 | Horiba Ltd | 光学式流体分析装置 |
JP2000214083A (ja) * | 1997-05-20 | 2000-08-04 | Zymequest Inc | 光学式センサ |
JP2003523236A (ja) * | 2000-02-08 | 2003-08-05 | ジェンデル・リミテッド | 装 置 |
JP2004037409A (ja) * | 2002-07-08 | 2004-02-05 | Toagosei Co Ltd | 光吸収スペクトル分析用セル、及びそれを用いるシラノール基濃度の測定方法 |
JP2004219409A (ja) * | 2002-12-20 | 2004-08-05 | Lifescan Inc | 滅菌され、較正されたバイオセンサーベースの医療デバイスの製造方法 |
JP2004354285A (ja) * | 2003-05-30 | 2004-12-16 | Shimamuratekku:Kk | 分取液体クロマトグラフィー用検出装置 |
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CA2676204A1 (en) | 2008-08-28 |
US20160313240A1 (en) | 2016-10-27 |
WO2008101637A2 (en) | 2008-08-28 |
US20190011356A1 (en) | 2019-01-10 |
EP2113076B1 (en) | 2014-10-22 |
CN101611305A (zh) | 2009-12-23 |
GB2446934A (en) | 2008-08-27 |
JP5180973B2 (ja) | 2013-04-10 |
US10816459B2 (en) | 2020-10-27 |
GB0703175D0 (en) | 2007-03-28 |
US20080212073A1 (en) | 2008-09-04 |
CN101611305B (zh) | 2011-09-14 |
US9404862B2 (en) | 2016-08-02 |
WO2008101637A3 (en) | 2008-10-30 |
US20130240747A1 (en) | 2013-09-19 |
GB0802836D0 (en) | 2008-03-26 |
US10094770B2 (en) | 2018-10-09 |
EP2113076A2 (en) | 2009-11-04 |
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