JP2010515706A5 - - Google Patents
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- Publication number
- JP2010515706A5 JP2010515706A5 JP2009545180A JP2009545180A JP2010515706A5 JP 2010515706 A5 JP2010515706 A5 JP 2010515706A5 JP 2009545180 A JP2009545180 A JP 2009545180A JP 2009545180 A JP2009545180 A JP 2009545180A JP 2010515706 A5 JP2010515706 A5 JP 2010515706A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- alkyl
- reaction
- substituents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000000034 method Methods 0.000 claims 16
- 150000001875 compounds Chemical class 0.000 claims 8
- 239000003795 chemical substances by application Substances 0.000 claims 5
- 230000002140 halogenating effect Effects 0.000 claims 5
- 150000003839 salts Chemical class 0.000 claims 5
- 125000001424 substituent group Chemical group 0.000 claims 5
- 229910052739 hydrogen Inorganic materials 0.000 claims 4
- 239000001257 hydrogen Substances 0.000 claims 4
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims 3
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 3
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims 3
- 229910052794 bromium Chemical group 0.000 claims 3
- 229910052801 chlorine Inorganic materials 0.000 claims 3
- 239000000460 chlorine Chemical group 0.000 claims 3
- 125000004435 hydrogen atom Chemical class [H]* 0.000 claims 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 claims 2
- 125000004093 cyano group Chemical group *C#N 0.000 claims 2
- 229910052736 halogen Inorganic materials 0.000 claims 2
- 150000002367 halogens Chemical class 0.000 claims 2
- 150000002391 heterocyclic compounds Chemical class 0.000 claims 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 2
- 239000011541 reaction mixture Substances 0.000 claims 2
- 125000004767 (C1-C4) haloalkoxy group Chemical group 0.000 claims 1
- 125000004765 (C1-C4) haloalkyl group Chemical group 0.000 claims 1
- KLSJWNVTNUYHDU-UHFFFAOYSA-N Amitrole Chemical compound NC1=NC=NN1 KLSJWNVTNUYHDU-UHFFFAOYSA-N 0.000 claims 1
- -1 C 1 -C 4 -Alkoxy Chemical group 0.000 claims 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 claims 1
- 125000003118 aryl group Chemical group 0.000 claims 1
- 125000004429 atom Chemical group 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 238000004821 distillation Methods 0.000 claims 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 1
- 229910052731 fluorine Inorganic materials 0.000 claims 1
- 239000011737 fluorine Substances 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- RLOWWWKZYUNIDI-UHFFFAOYSA-N phosphinic chloride Chemical group ClP=O RLOWWWKZYUNIDI-UHFFFAOYSA-N 0.000 claims 1
- WWYDYZMNFQIYPT-UHFFFAOYSA-N ru78191 Chemical compound OC(=O)C(C(O)=O)C1=CC=CC=C1 WWYDYZMNFQIYPT-UHFFFAOYSA-N 0.000 claims 1
- 229920006395 saturated elastomer Polymers 0.000 claims 1
- 150000003512 tertiary amines Chemical class 0.000 claims 1
- IMFACGCPASFAPR-UHFFFAOYSA-N tributylamine Chemical compound CCCCN(CCCC)CCCC IMFACGCPASFAPR-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07100430 | 2007-01-11 | ||
| PCT/EP2008/050254 WO2008084082A1 (de) | 2007-01-11 | 2008-01-10 | Verfahren zur herstellung arylsubstituierter anellierter pyrimidine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010515706A JP2010515706A (ja) | 2010-05-13 |
| JP2010515706A5 true JP2010515706A5 (enExample) | 2011-03-03 |
Family
ID=39406118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009545180A Withdrawn JP2010515706A (ja) | 2007-01-11 | 2008-01-10 | アリール置換縮合ピリミジンの製造方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20100087640A1 (enExample) |
| EP (1) | EP2111404A1 (enExample) |
| JP (1) | JP2010515706A (enExample) |
| CN (1) | CN101583613A (enExample) |
| WO (1) | WO2008084082A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8343977B2 (en) | 2009-12-30 | 2013-01-01 | Arqule, Inc. | Substituted triazolo-pyrimidine compounds |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3338292A1 (de) * | 1983-10-21 | 1985-05-02 | Basf Ag, 6700 Ludwigshafen | 7-amino-azolo(1,5-a)-pyrimidine und diese enthaltende fungizide |
| US4647411A (en) * | 1984-11-06 | 1987-03-03 | Nippon Shokubai Kagaku Kogyo Co., Ltd. | 5,6,7,8-tetrafluoroanthraquinone derivatives |
| DE3927888A1 (de) * | 1989-08-24 | 1991-02-28 | Philips Patentverwaltung | Wechselrichteranordnung |
| RU2147584C1 (ru) * | 1995-10-27 | 2000-04-20 | Американ Цианамид Компани | Способ получения дигалоидазолопиримидинов и способ получения дигидроксиазолопиримидинов |
| US6117876A (en) * | 1997-04-14 | 2000-09-12 | American Cyanamid Company | Fungicidal trifluorophenyl-triazolopyrimidines |
| US5986135A (en) * | 1998-09-25 | 1999-11-16 | American Cyanamid Company | Fungicidal trifluoromethylalkylamino-triazolopyrimidines |
| US6156925A (en) * | 1998-09-25 | 2000-12-05 | American Cyanamid Company | Process for the preparation of halogenated phenylmaloates |
| DE19850788A1 (de) * | 1998-11-04 | 2000-05-11 | Clariant Gmbh | Verfahren zur Herstellung von Trifluorbenzoesäuren |
| UA76486C2 (en) * | 2001-07-26 | 2006-08-15 | Basf Ag | 7-amino triazolopyrimidines, a process of praparation, a fungicidal preparations based thereon and a method to control phytopathogenic fungi |
| DE10223917A1 (de) * | 2002-05-29 | 2003-12-11 | Bayer Cropscience Ag | Pyrazolopyrimidine |
| AU2003289871A1 (en) * | 2002-11-15 | 2004-06-15 | Basf Aktiengesellschaft | 2-mercapto-substituted triazolopyrimidines, methods for the production thereof, the use of the same for controlling pathogenic fungi, and agents containing said compounds |
| EP1863752A1 (de) * | 2005-03-18 | 2007-12-12 | Basf Aktiengesellschaft | Verfahren zur herstellung von 5-halo-2,4,6-trifluorisophthalsäure |
-
2008
- 2008-01-10 EP EP08701400A patent/EP2111404A1/de not_active Withdrawn
- 2008-01-10 US US12/521,877 patent/US20100087640A1/en not_active Abandoned
- 2008-01-10 WO PCT/EP2008/050254 patent/WO2008084082A1/de not_active Ceased
- 2008-01-10 JP JP2009545180A patent/JP2010515706A/ja not_active Withdrawn
- 2008-01-10 CN CNA2008800021867A patent/CN101583613A/zh active Pending
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