JP2007515403A5 - - Google Patents

Info

Publication number

JP2007515403A5

JP2007515403A5 JP2006541320A JP2006541320A JP2007515403A5 JP 2007515403 A5 JP2007515403 A5 JP 2007515403A5 JP 2006541320 A JP2006541320 A JP 2006541320A JP 2006541320 A JP2006541320 A JP 2006541320A JP 2007515403 A5 JP2007515403 A5 JP 2007515403A5

Authority

JP

Japan

Prior art keywords

formula

compound

hydrogen

alcohol

solvent

Prior art date

2004-11-16

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Withdrawn

Links

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• 238000000034 method Methods 0.000 claims 23
• LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 15
• 150000001875 compounds Chemical class 0.000 claims 12
• 229910052739 hydrogen Inorganic materials 0.000 claims 10
• 239000001257 hydrogen Substances 0.000 claims 10
• OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims 9
• 239000002904 solvent Substances 0.000 claims 7
• 150000002431 hydrogen Chemical group 0.000 claims 6
• YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 claims 5
• 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims 4
• 125000003601 C2-C6 alkynyl group Chemical group 0.000 claims 4
• KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims 4
• 125000000217 alkyl group Chemical group 0.000 claims 4
• RUHCATDGSSLXPZ-UHFFFAOYSA-N dicarboxyazaniumylideneazanide Chemical compound OC(=O)[N+](=[N-])C(O)=O RUHCATDGSSLXPZ-UHFFFAOYSA-N 0.000 claims 4
• 238000001914 filtration Methods 0.000 claims 3
• 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims 3
• 239000000203 mixture Substances 0.000 claims 3
• 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 3
• UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 2
• 229910052736 halogen Inorganic materials 0.000 claims 2
• 150000002367 halogens Chemical class 0.000 claims 2
• 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 2
• 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
• 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 claims 2
• 125000002568 propynyl group Chemical group [*]C#CC([H])([H])[H] 0.000 claims 2
• 239000011541 reaction mixture Substances 0.000 claims 2
• LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 claims 2
• RIOQSEWOXXDEQQ-UHFFFAOYSA-N triphenylphosphine Chemical group C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1 RIOQSEWOXXDEQQ-UHFFFAOYSA-N 0.000 claims 2
• 150000001298 alcohols Chemical class 0.000 claims 1
• 125000003545 alkoxy group Chemical group 0.000 claims 1
• 238000004587 chromatography analysis Methods 0.000 claims 1
• 238000004821 distillation Methods 0.000 claims 1
• 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 1
• 238000000605 extraction Methods 0.000 claims 1
• 125000001424 substituent group Chemical group 0.000 claims 1
• 125000003944 tolyl group Chemical group 0.000 claims 1