JP2010512169A5 - - Google Patents
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- Publication number
- JP2010512169A5 JP2010512169A5 JP2009541546A JP2009541546A JP2010512169A5 JP 2010512169 A5 JP2010512169 A5 JP 2010512169A5 JP 2009541546 A JP2009541546 A JP 2009541546A JP 2009541546 A JP2009541546 A JP 2009541546A JP 2010512169 A5 JP2010512169 A5 JP 2010512169A5
- Authority
- JP
- Japan
- Prior art keywords
- oligonucleotide
- seq
- solvent
- nucleoside
- coupling solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86958806P | 2006-12-12 | 2006-12-12 | |
| US60/869,588 | 2006-12-12 | ||
| PCT/US2007/087183 WO2008073960A2 (en) | 2006-12-12 | 2007-12-12 | Oligonucleotides containing high concentrations of guanine monomers |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010512169A JP2010512169A (ja) | 2010-04-22 |
| JP2010512169A5 true JP2010512169A5 (https=) | 2011-03-24 |
| JP5389662B2 JP5389662B2 (ja) | 2014-01-15 |
Family
ID=39456527
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009541546A Active JP5389662B2 (ja) | 2006-12-12 | 2007-12-12 | 高濃度のグアニン・モノマーを含有するオリゴヌクレオチド |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US8586728B2 (https=) |
| EP (1) | EP2125854B1 (https=) |
| JP (1) | JP5389662B2 (https=) |
| CN (1) | CN101611048B (https=) |
| AU (1) | AU2007333147B2 (https=) |
| CA (1) | CA2671873C (https=) |
| WO (1) | WO2008073960A2 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102008063490B4 (de) * | 2008-12-17 | 2023-06-15 | Merck Patent Gmbh | Organische Elektrolumineszenzvorrichtung und Verfahren zum Einstellen des Farbortes einer weiß emittierenden Elektrolumineszenzvorrichtung |
| WO2012059510A1 (en) | 2010-11-02 | 2012-05-10 | Girindus America, Inc. | Back pressure control during solid-phase synthesis on polymeric supports |
| US10040048B1 (en) | 2014-09-25 | 2018-08-07 | Synthego Corporation | Automated modular system and method for production of biopolymers |
| PL3240801T3 (pl) | 2014-12-31 | 2021-06-14 | Checkmate Pharmaceuticals, Inc. | Skojarzona immunoterapia nowotworów |
| WO2017005818A1 (en) * | 2015-07-08 | 2017-01-12 | Kuros Biosciences Ag | Guanine-rich oligonucleotides |
| WO2017111137A1 (ja) | 2015-12-22 | 2017-06-29 | 味の素株式会社 | オリゴヌクレオチドの製造方法 |
| WO2017173334A1 (en) | 2016-04-01 | 2017-10-05 | Checkmate Pharmaceuticals, Inc. | Fc receptor-mediated drug delivery |
| US20190076814A1 (en) | 2017-09-11 | 2019-03-14 | Synthego Corporation | Biopolymer synthesis system and method |
| CN111246936B (zh) * | 2017-10-25 | 2022-05-03 | 深圳华大生命科学研究院 | 用于核酸合成的微流控芯片 |
| WO2019160866A2 (en) | 2018-02-13 | 2019-08-22 | Checkmate Pharmaceuticals, Inc. | Compositions and methods for tumor immunotherapy |
| BR112020020479A2 (pt) | 2018-04-09 | 2021-01-12 | Checkmate Pharmaceuticals | Empacotamento de oligonucleotídeos em partículas similares a vírus |
| EP3850096A1 (en) * | 2018-09-11 | 2021-07-21 | Amgen Inc. | Purification methods for guanine-rich oligonucleotides |
| CA3117823A1 (en) * | 2018-10-30 | 2020-05-07 | Toray Industries, Inc. | Inhibitor of non-specific binding of nucleic acid, hybridization reagent and nucleic acid hybridization method |
| WO2020093322A1 (zh) * | 2018-11-08 | 2020-05-14 | 深圳华大生命科学研究院 | 一种微流控芯片及其制备方法和dna合成方法 |
| EP4047004B1 (en) * | 2019-10-18 | 2024-03-06 | FUJIFILM Wako Pure Chemical Corporation | Phosphoramidite activator |
| US20230322842A1 (en) * | 2020-04-14 | 2023-10-12 | Sumitomo Chemical Company, Limited | Composition containing nucleic acid oligomer |
| CN114425443B (zh) * | 2020-10-29 | 2025-10-31 | 江苏金斯瑞生物科技有限公司 | 一种寡核苷酸合成催化剂 |
| GB202114688D0 (en) | 2021-10-14 | 2021-12-01 | Exactmer Ltd | Solution phase polymer synthesis |
| GB202414228D0 (en) | 2024-09-27 | 2024-11-13 | Exactmer Ltd | Solvent recycling in a liquid-phase process for preparing a defined monomoer sequence polymer |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60500817A (ja) * | 1983-06-01 | 1985-05-30 | ベツクマン・インストルメンツ・インコ−ポレ−テツド | ヌクレオシド・ホスホルアミダイト中間体の製造方法 |
| US20030050263A1 (en) * | 1994-07-15 | 2003-03-13 | The University Of Iowa Research Foundation | Methods and products for treating HIV infection |
| ATE292980T1 (de) | 1996-10-11 | 2005-04-15 | Univ California | Immunostimulierende oligonucleotidekonjugate |
| WO1998049195A1 (en) | 1997-04-29 | 1998-11-05 | Universiteit Utrecht | Corona virus-like particles as tools for vaccination and therapy |
| AU750702B2 (en) | 1997-05-01 | 2002-07-25 | Chiron Corporation | Use of virus-like particles as adjuvants |
| US6171591B1 (en) | 1997-12-08 | 2001-01-09 | Pentamer Pharmaceuticals, Inc. | Recombinant nodavirus compositions and methods |
| US6541438B1 (en) * | 1998-05-01 | 2003-04-01 | The Procter & Gamble Company | Laundry detergent and/or fabric care compositions comprising a modified cellulase |
| DE69929232T2 (de) * | 1998-10-21 | 2006-08-31 | The United States Government As Represented By The Department Of Health And Human Services | Virusähnliche partikel zur induktion von autoantikörpern |
| MXPA01005389A (es) | 1998-11-30 | 2003-03-27 | Cytos Biotechnology Ag | Presentacion molecular ordenada de antigenos, metodos de preparacion y uso. |
| WO2000046365A1 (en) | 1999-02-02 | 2000-08-10 | Biocache Pharmaceuticals, Inc. | Advanced antigen presentation platform |
| EP1156781B1 (en) | 1999-02-26 | 2005-06-08 | Chiron Corporation | Microemulsions with adsorbed macromolecules and microparticles |
| NZ517929A (en) * | 1999-09-25 | 2004-02-27 | Univ Iowa Res Found | Immunostimulatory nucleic acids |
| US6949520B1 (en) * | 1999-09-27 | 2005-09-27 | Coley Pharmaceutical Group, Inc. | Methods related to immunostimulatory nucleic acid-induced interferon |
| AU783118B2 (en) | 1999-09-27 | 2005-09-29 | Coley Pharmaceutical Gmbh | Methods related to immunostimulatory nucleic acid-induced interferon |
| PT1221968E (pt) | 1999-10-13 | 2010-04-16 | Novartis Vaccines & Diagnostic | Processo de obtenção de respostas imunes celulares de proteínas |
| EP1233783B9 (en) | 1999-11-24 | 2006-03-15 | Chiron Corporation | Hbv/hcv virus-like particle |
| AT409085B (de) | 2000-01-28 | 2002-05-27 | Cistem Biotechnologies Gmbh | Pharmazeutische zusammensetzung zur immunmodulation und herstellung von vakzinen |
| JP2003523398A (ja) | 2000-02-24 | 2003-08-05 | ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ | 樹状細胞のインビボ活性化によるアジュバント治療 |
| WO2002053141A2 (en) | 2000-12-14 | 2002-07-11 | Coley Pharmaceutical Group, Inc. | Inhibition of angiogenesis by nucleic acids |
| US20030050268A1 (en) * | 2001-03-29 | 2003-03-13 | Krieg Arthur M. | Immunostimulatory nucleic acid for treatment of non-allergic inflammatory diseases |
| CA2492823A1 (en) | 2001-09-14 | 2003-03-27 | Cytos Biotechnology Ag | In vivo activation of antigen presenting cells for enhancement of immune responses induced by virus like particles |
| DE60234375D1 (de) * | 2001-09-14 | 2009-12-24 | Cytos Biotechnology Ag | VERPACKUNG VON IMMUNSTIMULIERENDEM CpG IN VIRUSÄHNLICHEN PARTIKELN: HERSTELLUNGSVERFAHREN UND VERWENDUNG |
| US7524950B2 (en) * | 2001-10-31 | 2009-04-28 | Agilent Technologies, Inc. | Uses of cationic salts for polynucleotide synthesis |
| BR0311995A (pt) * | 2002-06-20 | 2005-04-05 | Cytos Biotechnology Ag | Partìculas semelhantes a vìrus empacotadas para o uso como adjuvantes: método de preparação e uso |
| AU2004224761A1 (en) * | 2003-03-26 | 2004-10-07 | Cytos Biotechnology Ag | HIV-peptide-carrier-conjugates |
| US7537767B2 (en) * | 2003-03-26 | 2009-05-26 | Cytis Biotechnology Ag | Melan-A- carrier conjugates |
| US20060210588A1 (en) * | 2003-03-26 | 2006-09-21 | Cytos Biotechnology Ag | Hiv-peptide-carrier-conjugates |
| RU2375076C2 (ru) | 2003-07-10 | 2009-12-10 | Цитос Биотехнологи Аг | Укомплектованные вирусоподобные частицы |
| US20060182793A1 (en) * | 2003-07-22 | 2006-08-17 | Cytos Biotechnology Ag | Cpg-packaged liposomes |
| JP4628686B2 (ja) * | 2004-02-25 | 2011-02-09 | 独立行政法人科学技術振興機構 | ホスホロアミダイトを含む３’末端ヌクレオシドユニット |
| CN101076546B (zh) * | 2004-09-02 | 2011-10-26 | Isis药物公司 | 用于低聚物合成的聚合珠 |
| MX2007003171A (es) * | 2004-09-21 | 2007-05-23 | Cytos Biotechnology Ag | Particulas tipo virus que comprenden una proteina de fusion de la proteina de cubierta de ap205 y un polipeptido antigenico. |
| CA2636139A1 (en) | 2005-12-14 | 2007-06-21 | Cytos Biotechnology Ag | Immunostimulatory nucleic acid packaged particles for the treatment of hypersensitivity |
-
2007
- 2007-12-12 US US11/954,511 patent/US8586728B2/en active Active
- 2007-12-12 CN CN2007800498509A patent/CN101611048B/zh active Active
- 2007-12-12 EP EP07865549.5A patent/EP2125854B1/en active Active
- 2007-12-12 JP JP2009541546A patent/JP5389662B2/ja active Active
- 2007-12-12 AU AU2007333147A patent/AU2007333147B2/en active Active
- 2007-12-12 WO PCT/US2007/087183 patent/WO2008073960A2/en not_active Ceased
- 2007-12-12 CA CA2671873A patent/CA2671873C/en active Active
-
2013
- 2013-10-15 US US14/054,068 patent/US20140200338A1/en not_active Abandoned
-
2015
- 2015-06-23 US US14/748,045 patent/US9914746B2/en active Active
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