AU2007333147B2 - Oligonucleotides containing high concentrations of guanine monomers - Google Patents

Oligonucleotides containing high concentrations of guanine monomers Download PDF

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Publication number
AU2007333147B2
AU2007333147B2 AU2007333147A AU2007333147A AU2007333147B2 AU 2007333147 B2 AU2007333147 B2 AU 2007333147B2 AU 2007333147 A AU2007333147 A AU 2007333147A AU 2007333147 A AU2007333147 A AU 2007333147A AU 2007333147 B2 AU2007333147 B2 AU 2007333147B2
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AU
Australia
Prior art keywords
oligonucleotide
solvent
seq
coupling
nucleoside
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AU2007333147A
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AU2007333147A1 (en
Inventor
Brian Stephen Sproat
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Kuros US LLC
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Kuros US LLC
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Assigned to CYTOS BIOTECHNOLOGY AG reassignment CYTOS BIOTECHNOLOGY AG Request for Assignment Assignors: INTEGRATED DNA TECHNOLOGIES, INC.
Priority to AU2013204442A priority Critical patent/AU2013204442A1/en
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Assigned to KUROS BIOSCIENCES AG reassignment KUROS BIOSCIENCES AG Request to Amend Deed and Register Assignors: CYTOS BIOTECHNOLOGY AG
Assigned to KUROS US LLC reassignment KUROS US LLC Request for Assignment Assignors: KUROS BIOSCIENCES AG
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2007333147A 2006-12-12 2007-12-12 Oligonucleotides containing high concentrations of guanine monomers Active AU2007333147B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2013204442A AU2013204442A1 (en) 2006-12-12 2013-04-12 Oligonucleotides Containing High Concentrations of Guanine Monomers

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US86958806P 2006-12-12 2006-12-12
US60/869,588 2006-12-12
PCT/US2007/087183 WO2008073960A2 (en) 2006-12-12 2007-12-12 Oligonucleotides containing high concentrations of guanine monomers

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2013204442A Division AU2013204442A1 (en) 2006-12-12 2013-04-12 Oligonucleotides Containing High Concentrations of Guanine Monomers

Publications (2)

Publication Number Publication Date
AU2007333147A1 AU2007333147A1 (en) 2008-06-19
AU2007333147B2 true AU2007333147B2 (en) 2013-12-19

Family

ID=39456527

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007333147A Active AU2007333147B2 (en) 2006-12-12 2007-12-12 Oligonucleotides containing high concentrations of guanine monomers

Country Status (7)

Country Link
US (3) US8586728B2 (https=)
EP (1) EP2125854B1 (https=)
JP (1) JP5389662B2 (https=)
CN (1) CN101611048B (https=)
AU (1) AU2007333147B2 (https=)
CA (1) CA2671873C (https=)
WO (1) WO2008073960A2 (https=)

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WO2012059510A1 (en) 2010-11-02 2012-05-10 Girindus America, Inc. Back pressure control during solid-phase synthesis on polymeric supports
US10040048B1 (en) 2014-09-25 2018-08-07 Synthego Corporation Automated modular system and method for production of biopolymers
PL3240801T3 (pl) 2014-12-31 2021-06-14 Checkmate Pharmaceuticals, Inc. Skojarzona immunoterapia nowotworów
WO2017005818A1 (en) * 2015-07-08 2017-01-12 Kuros Biosciences Ag Guanine-rich oligonucleotides
WO2017111137A1 (ja) 2015-12-22 2017-06-29 味の素株式会社 オリゴヌクレオチドの製造方法
WO2017173334A1 (en) 2016-04-01 2017-10-05 Checkmate Pharmaceuticals, Inc. Fc receptor-mediated drug delivery
US20190076814A1 (en) 2017-09-11 2019-03-14 Synthego Corporation Biopolymer synthesis system and method
CN111246936B (zh) * 2017-10-25 2022-05-03 深圳华大生命科学研究院 用于核酸合成的微流控芯片
WO2019160866A2 (en) 2018-02-13 2019-08-22 Checkmate Pharmaceuticals, Inc. Compositions and methods for tumor immunotherapy
BR112020020479A2 (pt) 2018-04-09 2021-01-12 Checkmate Pharmaceuticals Empacotamento de oligonucleotídeos em partículas similares a vírus
EP3850096A1 (en) * 2018-09-11 2021-07-21 Amgen Inc. Purification methods for guanine-rich oligonucleotides
CA3117823A1 (en) * 2018-10-30 2020-05-07 Toray Industries, Inc. Inhibitor of non-specific binding of nucleic acid, hybridization reagent and nucleic acid hybridization method
WO2020093322A1 (zh) * 2018-11-08 2020-05-14 深圳华大生命科学研究院 一种微流控芯片及其制备方法和dna合成方法
EP4047004B1 (en) * 2019-10-18 2024-03-06 FUJIFILM Wako Pure Chemical Corporation Phosphoramidite activator
US20230322842A1 (en) * 2020-04-14 2023-10-12 Sumitomo Chemical Company, Limited Composition containing nucleic acid oligomer
CN114425443B (zh) * 2020-10-29 2025-10-31 江苏金斯瑞生物科技有限公司 一种寡核苷酸合成催化剂
GB202114688D0 (en) 2021-10-14 2021-12-01 Exactmer Ltd Solution phase polymer synthesis
GB202414228D0 (en) 2024-09-27 2024-11-13 Exactmer Ltd Solvent recycling in a liquid-phase process for preparing a defined monomoer sequence polymer

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EP1719778A1 (en) * 2004-02-25 2006-11-08 Japan Science and Technology Agency 3'-terminal nucleoside unit containing phosphoramidite

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Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
WO2005014110A1 (en) * 2003-07-22 2005-02-17 Cytos Biotechnology Ag Cpg-packaged liposomes
EP1719778A1 (en) * 2004-02-25 2006-11-08 Japan Science and Technology Agency 3'-terminal nucleoside unit containing phosphoramidite

Also Published As

Publication number Publication date
CN101611048B (zh) 2012-11-07
EP2125854A2 (en) 2009-12-02
US8586728B2 (en) 2013-11-19
US20160145293A1 (en) 2016-05-26
AU2007333147A1 (en) 2008-06-19
WO2008073960A3 (en) 2008-08-07
JP2010512169A (ja) 2010-04-22
US9914746B2 (en) 2018-03-13
CN101611048A (zh) 2009-12-23
JP5389662B2 (ja) 2014-01-15
CA2671873C (en) 2018-10-09
CA2671873A1 (en) 2008-06-19
US20140200338A1 (en) 2014-07-17
EP2125854B1 (en) 2016-10-26
WO2008073960A2 (en) 2008-06-19
US20080139797A1 (en) 2008-06-12

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