|
US6241704B1
(en)
*
|
1901-11-22 |
2001-06-05 |
Sims Deltec, Inc. |
Drug pump systems and methods
|
|
US4211771A
(en)
*
|
1971-06-01 |
1980-07-08 |
Robins Ronald K |
Treatment of human viral diseases with 1-B-D-ribofuranosyl-1,2,4-triazole-3-carboxamide
|
|
US3760984A
(en)
*
|
1971-09-29 |
1973-09-25 |
Alza Corp |
Osmotically powered agent dispensing device with filling means
|
|
US4036228A
(en)
*
|
1975-09-11 |
1977-07-19 |
Alza Corporation |
Osmotic dispenser with gas generating means
|
|
GB1555654A
(en)
*
|
1977-06-25 |
1979-11-14 |
Exxon Research Engineering Co |
Agricultural burner apparatus
|
|
US4016880A
(en)
*
|
1976-03-04 |
1977-04-12 |
Alza Corporation |
Osmotically driven active agent dispenser
|
|
US4111203A
(en)
*
|
1976-11-22 |
1978-09-05 |
Alza Corporation |
Osmotic system with means for improving delivery kinetics of system
|
|
US4111202A
(en)
*
|
1976-11-22 |
1978-09-05 |
Alza Corporation |
Osmotic system for the controlled and delivery of agent over time
|
|
NO154918C
(no)
*
|
1977-08-27 |
1987-01-14 |
Bayer Ag |
Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin.
|
|
US4203442A
(en)
*
|
1977-08-29 |
1980-05-20 |
Alza Corporation |
Device for delivering drug to a fluid environment
|
|
DE2834122A1
(de)
*
|
1978-08-03 |
1980-02-14 |
Bayer Ag |
Verfahren zur herstellung von 6-amino-6-desoxy-l-sorbose
|
|
US4203440A
(en)
*
|
1978-10-23 |
1980-05-20 |
Alza Corporation |
Device having variable volume chamber for dispensing useful agent
|
|
DE2853573A1
(de)
*
|
1978-12-12 |
1980-07-03 |
Bayer Ag |
Herstellung von n-substituierten derivaten des l-desoxynojirimycins
|
|
US4210139A
(en)
*
|
1979-01-17 |
1980-07-01 |
Alza Corporation |
Osmotic device with compartment for governing concentration of agent dispensed from device
|
|
US4692147A
(en)
*
|
1980-04-02 |
1987-09-08 |
Medtronic, Inc. |
Drug administration device
|
|
US4350155A
(en)
*
|
1980-04-02 |
1982-09-21 |
Medtronic, Inc. |
Body implantable medical infusion system
|
|
US4311137A
(en)
*
|
1980-04-30 |
1982-01-19 |
Sherwood Medical Industries Inc. |
Infusion device
|
|
DE3038901A1
(de)
*
|
1980-10-15 |
1982-05-06 |
Bayer Ag, 5090 Leverkusen |
Verfahren zur herstellung von n-substituierten derivaten des 1-desoxynojirimycins
|
|
US4327725A
(en)
*
|
1980-11-25 |
1982-05-04 |
Alza Corporation |
Osmotic device with hydrogel driving member
|
|
US6936694B1
(en)
*
|
1982-05-06 |
2005-08-30 |
Intermune, Inc. |
Manufacture and expression of large structural genes
|
|
US4531937A
(en)
*
|
1983-01-24 |
1985-07-30 |
Pacesetter Systems, Inc. |
Introducer catheter apparatus and method of use
|
|
US4725852A
(en)
*
|
1985-05-09 |
1988-02-16 |
Burlington Industries, Inc. |
Random artificially perturbed liquid apparatus and method
|
|
DE3543999A1
(de)
*
|
1985-12-13 |
1987-06-19 |
Bayer Ag |
Hochreine acarbose
|
|
US4865845A
(en)
*
|
1986-03-21 |
1989-09-12 |
Alza Corporation |
Release rate adjustment of osmotic or diffusional delivery devices
|
|
DE3611841A1
(de)
*
|
1986-04-09 |
1987-10-15 |
Bayer Ag |
Verfahren zur herstellung von 1-desoxynojirimycin und dessen n-derivaten
|
|
US4861892A
(en)
*
|
1988-02-12 |
1989-08-29 |
G. D. Searle & Co. |
Method for synthesis of deoxymannojirimycin
|
|
US5017563A
(en)
*
|
1988-06-23 |
1991-05-21 |
Merrell Dow Pharmaceuticals Inc. |
Castanospermine esters and glycosides
|
|
US4855173A
(en)
*
|
1988-08-11 |
1989-08-08 |
Dore Peter B |
Repair process for a fibre reinforced structure
|
|
US4910310A
(en)
*
|
1988-10-03 |
1990-03-20 |
G. D. Searle & Co. |
Synthesis of N-substituted 1,5-dideoxy-1,5-imino-L-fucitol derivatives
|
|
US4894388A
(en)
*
|
1988-12-22 |
1990-01-16 |
Monsanto Company |
Glycosidase inhibitors and use thereof
|
|
US5011929A
(en)
*
|
1989-05-15 |
1991-04-30 |
Monsanto Company |
Synthesis of mannojirimycin derivatives
|
|
US5017704A
(en)
*
|
1989-06-27 |
1991-05-21 |
Monsanto Company |
Fucosidase inhibitor
|
|
US5100797A
(en)
*
|
1989-06-27 |
1992-03-31 |
Monsanto Company |
Fucosidase inhibitors
|
|
US5043273A
(en)
*
|
1989-08-17 |
1991-08-27 |
Monsanto Company |
Phosphorylated glycosidase inhibitor prodrugs
|
|
US5112614A
(en)
*
|
1989-09-14 |
1992-05-12 |
Alza Corporation |
Implantable delivery dispenser
|
|
US4994572A
(en)
*
|
1989-10-12 |
1991-02-19 |
Monsanto Company |
Synthesis of nojirimycin derivatives
|
|
US4996329A
(en)
*
|
1989-10-20 |
1991-02-26 |
Monsanto Company |
Derivatives of 1,4-dideoxy-1,4-imino-D-mannitol and a process for their preparation
|
|
US5013842A
(en)
*
|
1990-01-22 |
1991-05-07 |
Monsanto Company |
Synthesis of chiral pyrrolidine and piperidine glycosidase inhibitors
|
|
US5151519A
(en)
*
|
1990-05-07 |
1992-09-29 |
G. D. Searle & Co. |
Process for the preparation of 1,5-(alkylimino)-1,5-dideoxy-d-glucitol and derivatives thereof
|
|
US5234693A
(en)
*
|
1990-07-11 |
1993-08-10 |
Alza Corporation |
Delivery device with a protective sleeve
|
|
US5234692A
(en)
*
|
1990-07-11 |
1993-08-10 |
Alza Corporation |
Delivery device with a protective sleeve
|
|
ES2087277T3
(es)
*
|
1990-09-20 |
1996-07-16 |
Monsanto Co |
Procedimiento para producir 1-desoxinojirimicina n-sustituida.
|
|
US5200523A
(en)
*
|
1990-10-10 |
1993-04-06 |
Monsanto Company |
Synthesis of nojirimycin derivatives
|
|
US5137727A
(en)
*
|
1991-06-12 |
1992-08-11 |
Alza Corporation |
Delivery device providing beneficial agent stability
|
|
US5401645A
(en)
*
|
1992-03-16 |
1995-03-28 |
Monsanto Company |
Process for producing n-substituted polyhydroxy nitrogen-containing heterocycles utilizing acetobacteraceae and corynebacterium
|
|
US5382657A
(en)
*
|
1992-08-26 |
1995-01-17 |
Hoffmann-La Roche Inc. |
Peg-interferon conjugates
|
|
US5545143A
(en)
*
|
1993-01-21 |
1996-08-13 |
T. S. I. Medical |
Device for subcutaneous medication delivery
|
|
US5286877A
(en)
*
|
1993-02-01 |
1994-02-15 |
G. D. Searle & Co. |
Synthesis of 1,4-dideoxy-1,4-imino-L-arabinitol
|
|
US5399567A
(en)
*
|
1993-05-13 |
1995-03-21 |
Monsanto Company |
Method of treating cholera
|
|
US5951974A
(en)
*
|
1993-11-10 |
1999-09-14 |
Enzon, Inc. |
Interferon polymer conjugates
|
|
JP3628021B2
(ja)
*
|
1994-01-13 |
2005-03-09 |
ジー．ディー．サール アンド カンパニー |
Ｂ型肝炎ウイルス感染症の治療のための１，５−ジデオキシ−１，５−イミノ−ｄ−グルシトールのｎ−アルキル誘導体の使用
|
|
WO1995022975A1
(en)
*
|
1994-02-25 |
1995-08-31 |
G.D. Searle & Co. |
Use of 1-deoxynojirimycin and its derivatives for treating mammals infected with respiratory syncytial virus
|
|
US5443450A
(en)
*
|
1994-04-29 |
1995-08-22 |
Medtronic, Inc. |
Medication delivery device and method of construction
|
|
US5559101A
(en)
*
|
1994-10-24 |
1996-09-24 |
Genencor International, Inc. |
L-ribofuranosyl nucleosides
|
|
DE19509634C1
(de)
*
|
1995-03-17 |
1996-03-28 |
Fresenius Ag |
Implantierbare Infusionspumpe
|
|
US5643207A
(en)
*
|
1995-04-28 |
1997-07-01 |
Medtronic, Inc. |
Implantable techniques for infusing a therapeutic agent with endogenous bodily fluid
|
|
US6387365B1
(en)
*
|
1995-05-19 |
2002-05-14 |
Schering Corporation |
Combination therapy for chronic hepatitis C infection
|
|
US5908621A
(en)
*
|
1995-11-02 |
1999-06-01 |
Schering Corporation |
Polyethylene glycol modified interferon therapy
|
|
PL189137B1
(pl)
*
|
1996-02-02 |
2005-06-30 |
Alza Corp |
Implantowane urządzenie do dostarczania substancji aktywnej
|
|
HUP0001186A3
(en)
*
|
1996-10-16 |
2002-04-29 |
Icn Pharmaceuticals Inc Costa |
Purine l-nucleosides,analogs and pharmaceutical compositions thereof
|
|
CZ298749B6
(cs)
*
|
1996-10-18 |
2008-01-16 |
Vertex Pharmaceuticals Incorporated |
Inhibitory serinových proteáz a farmaceutické prostředky s jejich obsahem
|
|
US20030100532A1
(en)
*
|
1997-02-14 |
2003-05-29 |
Gary S. Jacob |
Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy for treating hepatitis virus infections
|
|
GB2324223A
(en)
*
|
1997-04-11 |
1998-10-14 |
Northern Telecom Ltd |
Network management
|
|
US6171276B1
(en)
*
|
1997-08-06 |
2001-01-09 |
Pharmacia & Upjohn Ab |
Automated delivery device and method for its operation
|
|
US6172046B1
(en)
*
|
1997-09-21 |
2001-01-09 |
Schering Corporation |
Combination therapy for eradicating detectable HCV-RNA in patients having chronic Hepatitis C infection
|
|
US5914128A
(en)
*
|
1997-12-22 |
1999-06-22 |
Schering Corporation |
Orally administrable solid dosage form
|
|
DK0991415T3
(da)
*
|
1997-12-22 |
2003-06-16 |
Schering Corp |
Faste, oralt indgivelige dosisformer for ribavirin og fremgangsmåde til fremstilling af disse
|
|
US6423695B1
(en)
*
|
1998-01-13 |
2002-07-23 |
Ribapharm, Inc. |
Cytokine related treatments of disease
|
|
US6689759B1
(en)
*
|
1998-02-12 |
2004-02-10 |
G. D. Searle & Co. |
Methods of Treating hepatitis virus infections with N-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy
|
|
EP1066247B1
(en)
*
|
1998-03-31 |
2006-11-22 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of serine proteases, particularly hepatitis c virus ns3 protease
|
|
US6323180B1
(en)
*
|
1998-08-10 |
2001-11-27 |
Boehringer Ingelheim (Canada) Ltd |
Hepatitis C inhibitor tri-peptides
|
|
CA2343522A1
(en)
*
|
1998-09-04 |
2000-03-16 |
Viropharma Incorporated |
Methods for treating or preventing viral infections and associated diseases
|
|
US6277830B1
(en)
*
|
1998-10-16 |
2001-08-21 |
Schering Corporation |
5′-amino acid esters of ribavirin and the use of same to treat hepatitis C with interferon
|
|
US6308099B1
(en)
*
|
1998-11-13 |
2001-10-23 |
Intermedics Inc. |
Implantable device and programmer system which permits multiple programmers
|
|
ES2311921T3
(es)
*
|
1999-02-12 |
2009-02-16 |
United Therapeutics Corporation |
N-(8,8,8-trifluorooctil)1-5,-didesoxi-1,5-imino-d-glucitol para tratar infecciones por el virus de la hepatitis.
|
|
US6198966B1
(en)
*
|
1999-02-26 |
2001-03-06 |
Medtronic, Inc. |
Recirculating implantable drug delivery system
|
|
US6608027B1
(en)
*
|
1999-04-06 |
2003-08-19 |
Boehringer Ingelheim (Canada) Ltd |
Macrocyclic peptides active against the hepatitis C virus
|
|
US7256005B2
(en)
*
|
1999-08-10 |
2007-08-14 |
The Chancellor, Masters And Scholars Of The University Of Oxford |
Methods for identifying iminosugar derivatives that inhibit HCV p7 ion channel activity
|
|
CN1422156A
(zh)
*
|
2000-02-14 |
2003-06-04 |
法马西亚公司 |
N－取代的－1,5－二脱氧－1,5－亚氨基－d－葡萄糖醇化合物在治疗肝炎病毒感染中的用途
|
|
US6689784B2
(en)
*
|
2000-03-29 |
2004-02-10 |
Vertex Pharmaceuticals Incorporated |
Carbamate caspase inhibitors and uses thereof
|
|
TR200200767T1
(tr)
*
|
2000-05-23 |
2002-09-23 |
Vertex Pharmaceuticals Incorporated |
Kaspaz engelleyiciler ve kullanımları
|
|
DE10031274A1
(de)
*
|
2000-06-27 |
2002-01-10 |
Bosch Gmbh Robert |
Wischarm für Kraftfahrzeuge
|
|
GB0110832D0
(en)
*
|
2001-05-03 |
2001-06-27 |
Virogen Ltd |
Antiviral compounds
|
|
AU2002348971A1
(en)
*
|
2001-10-12 |
2003-04-28 |
Stefana M. Petrescu |
Ph-sensitive liposomes for targeted drug delivery
|
|
US7091184B2
(en)
*
|
2002-02-01 |
2006-08-15 |
Boehringer Ingelheim International Gmbh |
Hepatitis C inhibitor tri-peptides
|
|
WO2005120479A1
(en)
*
|
2004-06-09 |
2005-12-22 |
Gpc Biotech Ag |
Use of selenium or a selenium salt and a retinoid acid or a retinoid in the treatment of viral hepatitis c
|
|
WO2006085141A2
(en)
*
|
2004-08-13 |
2006-08-17 |
Migenix Inc. |
Compositions and methods for treating or preventing hepadnaviridae infection
|
|
US20060093577A1
(en)
*
|
2004-10-06 |
2006-05-04 |
Migenix Inc. |
Combination anti-viral compositions and methods of use
|
|
MY141025A
(en)
*
|
2004-10-29 |
2010-02-25 |
Vertex Pharma |
Dose forms
|
|
EA200701669A1
(ru)
*
|
2005-02-09 |
2008-02-28 |
Мидженикс Инк. |
Композиции и способы лечения или предотвращения инфекций, вызванных вирусами семейства flaviviridae
|
|
KR20090040906A
(ko)
*
|
2006-08-02 |
2009-04-27 |
유나이티드 세러퓨틱스 코오포레이션 |
바이러스 감염의 리포솜 치료
|