JP2010509920A5 - - Google Patents
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- JP2010509920A5 JP2010509920A5 JP2009537358A JP2009537358A JP2010509920A5 JP 2010509920 A5 JP2010509920 A5 JP 2010509920A5 JP 2009537358 A JP2009537358 A JP 2009537358A JP 2009537358 A JP2009537358 A JP 2009537358A JP 2010509920 A5 JP2010509920 A5 JP 2010509920A5
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- JP
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- Prior art keywords
- cancer
- antibody
- variable region
- chain variable
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86605806P | 2006-11-15 | 2006-11-15 | |
| PCT/US2007/084792 WO2008076560A2 (en) | 2006-11-15 | 2007-11-15 | Human monoclonal antibodies to btla and methods of use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010509920A JP2010509920A (ja) | 2010-04-02 |
| JP2010509920A5 true JP2010509920A5 (https=) | 2010-05-13 |
Family
ID=39536943
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009537358A Withdrawn JP2010509920A (ja) | 2006-11-15 | 2007-11-15 | Ｂｔｌａに対するヒトモノクローナル抗体および使用方法 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US8247537B2 (https=) |
| EP (1) | EP2097447A4 (https=) |
| JP (1) | JP2010509920A (https=) |
| KR (1) | KR20090088891A (https=) |
| CN (1) | CN101578296A (https=) |
| AR (1) | AR063840A1 (https=) |
| AU (1) | AU2007334264A1 (https=) |
| CA (1) | CA2669921A1 (https=) |
| CL (1) | CL2007003291A1 (https=) |
| EA (1) | EA200970477A1 (https=) |
| IL (1) | IL198729A0 (https=) |
| MX (1) | MX2009005189A (https=) |
| NO (1) | NO20092285L (https=) |
| NZ (1) | NZ577085A (https=) |
| TW (1) | TW200837081A (https=) |
| WO (1) | WO2008076560A2 (https=) |
| ZA (1) | ZA200903775B (https=) |
Families Citing this family (67)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US8349320B2 (en) | 2004-12-09 | 2013-01-08 | La Jolla Institute For Allergy And Immunology | Compositions and methods for modulating responses mediated or associated with BTLA activity |
| KR20090088891A (ko) | 2006-11-15 | 2009-08-20 | 메다렉스, 인코포레이티드 | 비티엘에이에 대한 인간 단일클론 항체 및 이용 방법 |
| US20120064096A1 (en) * | 2009-03-17 | 2012-03-15 | Universite De La Mediterranee | BTLA Antibodies and Uses Thereof |
| US8404811B2 (en) | 2009-05-08 | 2013-03-26 | Genentech, Inc. | Humanized anti-EGFL7 antibodies and methods using same |
| US8303952B2 (en) * | 2009-06-08 | 2012-11-06 | Washington University | Methods for inducing in vivo tolerance |
| CN102762593B (zh) * | 2009-07-31 | 2015-05-20 | 梅达雷克斯有限责任公司 | 抗btla的完全人抗体 |
| RS57413B1 (sr) * | 2012-03-28 | 2018-09-28 | Sanofi Sa | Antitela za ligande bradikinin b1 receptora |
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| KR102815803B1 (ko) * | 2015-12-02 | 2025-06-05 | 주식회사 에스티사이언스 | 당화된 btla(b- 및 t-림프구 약화인자)에 특이적인 항체 |
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| BR112019008345A8 (pt) * | 2016-10-25 | 2023-03-07 | Inst Nat Sante Rech Med | Anticorpos monoclonais ligados à isoforma transmembrana cd160 |
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| CN110997724A (zh) | 2017-06-06 | 2020-04-10 | 斯特库伯株式会社 | 使用结合btn1a1或btn1a1-配体的抗体和分子治疗癌症的方法 |
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| CN111511762B (zh) * | 2017-08-21 | 2025-05-06 | 天演药业公司 | 抗cd137分子及其用途 |
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| CN110790837A (zh) | 2018-08-02 | 2020-02-14 | 上海君实生物医药科技股份有限公司 | 抗btla抗体 |
| CN110950953B (zh) * | 2018-09-26 | 2022-05-13 | 福州拓新天成生物科技有限公司 | 抗b7-h3的单克隆抗体及其在细胞治疗中的应用 |
| GB201820554D0 (en) * | 2018-12-17 | 2019-01-30 | Univ Oxford Innovation Ltd | BTLA antibodies |
| CN113614109A (zh) | 2018-12-21 | 2021-11-05 | Ose免疫疗法公司 | 双功能抗pd-1/il-7分子 |
| WO2020165374A1 (en) | 2019-02-14 | 2020-08-20 | Ose Immunotherapeutics | Bifunctional molecule comprising il-15ra |
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| AU2020406083A1 (en) | 2019-12-17 | 2022-06-16 | Boehringer Ingelheim International Gmbh | Bifunctional molecules comprising an IL-7 variant |
| JP2023509359A (ja) | 2019-12-17 | 2023-03-08 | フラグシップ パイオニアリング イノベーションズ ブイ，インコーポレーテッド | 鉄依存性細胞分解の誘導物質との併用抗癌療法 |
| GB202008860D0 (en) * | 2020-06-11 | 2020-07-29 | Univ Oxford Innovation Ltd | BTLA antibodies |
| JP2023532339A (ja) | 2020-06-29 | 2023-07-27 | フラグシップ パイオニアリング イノベーションズ ブイ，インコーポレーテッド | サノトランスミッションを促進するためにエンジニアリングされたウイルス及び癌の処置におけるそれらの使用 |
| CN114457025A (zh) * | 2020-10-30 | 2022-05-10 | 未来智人再生医学研究院(广州)有限公司 | 一种表达btla阻断物的多能干细胞或其衍生物及应用 |
| CN114657137A (zh) * | 2020-12-22 | 2022-06-24 | 未来智人再生医学研究院(广州)有限公司 | 一种表达靶向BTLA的shRNA和/或shRNA-miR的多能干细胞或其衍生物 |
| CN115073599B (zh) * | 2021-03-16 | 2023-04-28 | 北京天广实生物技术股份有限公司 | 结合pd-l1的抗体及其用途 |
| JP2024512669A (ja) | 2021-03-31 | 2024-03-19 | フラグシップ パイオニアリング イノベーションズ ブイ，インコーポレーテッド | タノトランスミッションポリペプチド及び癌の処置におけるそれらの使用 |
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-
2007
- 2007-11-15 KR KR1020097011249A patent/KR20090088891A/ko not_active Withdrawn
- 2007-11-15 TW TW096143297A patent/TW200837081A/zh unknown
- 2007-11-15 NZ NZ577085A patent/NZ577085A/en not_active IP Right Cessation
- 2007-11-15 AR ARP070105084A patent/AR063840A1/es not_active Application Discontinuation
- 2007-11-15 AU AU2007334264A patent/AU2007334264A1/en not_active Abandoned
- 2007-11-15 WO PCT/US2007/084792 patent/WO2008076560A2/en not_active Ceased
- 2007-11-15 CN CNA2007800494156A patent/CN101578296A/zh active Pending
- 2007-11-15 US US12/515,004 patent/US8247537B2/en active Active
- 2007-11-15 EP EP07871479A patent/EP2097447A4/en not_active Withdrawn
- 2007-11-15 JP JP2009537358A patent/JP2010509920A/ja not_active Withdrawn
- 2007-11-15 CL CL200703291A patent/CL2007003291A1/es unknown
- 2007-11-15 MX MX2009005189A patent/MX2009005189A/es not_active Application Discontinuation
- 2007-11-15 EA EA200970477A patent/EA200970477A1/ru unknown
- 2007-11-15 CA CA002669921A patent/CA2669921A1/en not_active Abandoned
-
2009
- 2009-05-13 IL IL198729A patent/IL198729A0/en unknown
- 2009-05-29 ZA ZA200903775A patent/ZA200903775B/xx unknown
- 2009-06-12 NO NO20092285A patent/NO20092285L/no not_active Application Discontinuation
-
2012
- 2012-07-19 US US13/553,205 patent/US8580259B2/en active Active
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