JP2003532409A5 - - Google Patents
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- JP2003532409A5 JP2003532409A5 JP2001582397A JP2001582397A JP2003532409A5 JP 2003532409 A5 JP2003532409 A5 JP 2003532409A5 JP 2001582397 A JP2001582397 A JP 2001582397A JP 2001582397 A JP2001582397 A JP 2001582397A JP 2003532409 A5 JP2003532409 A5 JP 2003532409A5
- Authority
- JP
- Japan
- Prior art keywords
- variable region
- antigen
- human
- dendritic cells
- chain variable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20312600P | 2000-05-08 | 2000-05-08 | |
| US60/203,126 | 2000-05-08 | ||
| US23073900P | 2000-09-07 | 2000-09-07 | |
| US60/230,739 | 2000-09-07 | ||
| PCT/US2001/015114 WO2001085798A2 (en) | 2000-05-08 | 2001-05-08 | Human monoclonal antibodies to dendritic cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2003532409A JP2003532409A (ja) | 2003-11-05 |
| JP2003532409A5 true JP2003532409A5 (https=) | 2008-06-19 |
| JP5007409B2 JP5007409B2 (ja) | 2012-08-22 |
Family
ID=26898333
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001582397A Expired - Fee Related JP5007409B2 (ja) | 2000-05-08 | 2001-05-08 | 樹状細胞に対するヒトモノクローナル抗体 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7563876B2 (https=) |
| EP (1) | EP1282646B1 (https=) |
| JP (1) | JP5007409B2 (https=) |
| KR (2) | KR100881471B1 (https=) |
| CN (1) | CN1452636B (https=) |
| AT (1) | ATE553131T1 (https=) |
| AU (2) | AU6138301A (https=) |
| CA (1) | CA2408594A1 (https=) |
| DK (1) | DK1282646T3 (https=) |
| IL (2) | IL152652A0 (https=) |
| MX (1) | MXPA02010869A (https=) |
| NZ (1) | NZ534864A (https=) |
| WO (1) | WO2001085798A2 (https=) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100881471B1 (ko) | 2000-05-08 | 2009-02-05 | 셀덱스 쎄라퓨틱스, 인크. | 수상세포에 대한 인간 모노클로날 항체 |
| US7560534B2 (en) | 2000-05-08 | 2009-07-14 | Celldex Research Corporation | Molecular conjugates comprising human monoclonal antibodies to dendritic cells |
| US20060222633A1 (en) * | 2000-05-11 | 2006-10-05 | Yale University | Prevention, decrease, and/or treatment of immunoreactivity by depleting and/or inactivating antigen presenting cells in the host |
| US7754208B2 (en) | 2001-01-17 | 2010-07-13 | Trubion Pharmaceuticals, Inc. | Binding domain-immunoglobulin fusion proteins |
| NZ527977A (en) | 2001-02-12 | 2005-10-28 | Medarex Inc | Human monoclonal antibodies to FC alpha receptor (CD89) |
| JP5355839B2 (ja) | 2001-10-23 | 2013-11-27 | ピーエスエムエー デベロプメント カンパニー, エル.エル.シー. | Psma抗体およびタンパク質マルチマー |
| US20050215472A1 (en) | 2001-10-23 | 2005-09-29 | Psma Development Company, Llc | PSMA formulations and uses thereof |
| US9259459B2 (en) | 2003-01-31 | 2016-02-16 | Celldex Therapeutics Inc. | Antibody vaccine conjugates and uses therefor |
| ATE552860T1 (de) * | 2003-01-31 | 2012-04-15 | Celldex Res Corp | Antikörper-vakzine-konjugate und ihre verwendungen |
| CA2566473A1 (en) * | 2004-05-17 | 2005-12-08 | Board Of Trustees Of The University Of Illinois | Uses of bispecific antibody (biab) coated dendritic cells pulsed with antigens |
| WO2006073921A2 (en) * | 2004-12-30 | 2006-07-13 | The Rockefeller University | Compositions and methods for enhanced dendritic cell maturation and function |
| RU2423381C2 (ru) | 2005-07-25 | 2011-07-10 | Трабьон Фармасьютикалз, Инк. | Снижение количества в-клеток с использованием cd37-специфических и cd20-специфических связывающих молекул |
| NZ573646A (en) | 2006-06-12 | 2012-04-27 | Wyeth Llc | Single-chain multivalent binding proteins with effector function |
| JP2008029319A (ja) * | 2006-06-28 | 2008-02-14 | Yoichiro Iwakura | 樹状細胞免疫受容体遺伝子ノックアウト疾患モデル動物 |
| CN101888856B (zh) | 2007-11-07 | 2014-08-27 | 塞尔德克斯医疗公司 | 结合人树突和上皮细胞205(dec-205)的抗体 |
| RU2531754C2 (ru) | 2008-04-11 | 2014-10-27 | ЭМЕРДЖЕНТ ПРОДАКТ ДИВЕЛОПМЕНТ СИЭТЛ,ЭлЭлСи,US | Связывающееся с cd37 иммунотерапевтическое средство и его комбинация с бифункциональным химиотерапевтическим средством |
| AU2011207189B2 (en) | 2008-08-08 | 2014-01-16 | Immunomedics, Inc. | Detection of early-stage pancreatic adenocarcinoma |
| CN102186499B (zh) * | 2008-08-20 | 2015-05-20 | Ibc医药公司 | 用于癌症治疗的对接和锁定(dnl)疫苗 |
| EP2326350B1 (en) | 2008-09-08 | 2013-09-04 | Psma Development Company, L.L.C. | Compounds for killing psma-expressing, taxane-resistant cancer cells |
| DK2406289T3 (en) | 2009-03-10 | 2017-05-01 | Baylor Res Inst | ANTIGEN PRESENTING CELL TARGETED ANTIVIRUS VACCINES |
| AU2010222942B2 (en) | 2009-03-10 | 2013-01-10 | Baylor Research Institute | Anti-CD40 antibodies and uses thereof |
| EP2477655A4 (en) | 2009-09-14 | 2014-02-12 | Baylor Res Inst | VACCINES TREATED ON LANGERHANS CELLS |
| ES2709654T3 (es) | 2011-04-29 | 2019-04-17 | Apexigen Inc | Anticuerpos anti-CD40 y métodos de uso |
| CA2850572A1 (en) * | 2011-10-20 | 2013-04-25 | Esbatech, A Novartis Company Llc | Stable multiple antigen-binding antibody |
| US20150299315A1 (en) * | 2012-10-22 | 2015-10-22 | Becton, Dickinson And Company | Non-b-lineage cells capable of producing antibody |
| KR102270618B1 (ko) | 2012-10-30 | 2021-06-30 | 아펙시젠, 인코포레이티드 | 항-cd40 항체 및 사용 방법 |
| CN120939216A (zh) | 2014-01-13 | 2025-11-14 | 贝勒研究院 | 抗hpv和hpv相关的疾病的新疫苗 |
| WO2017053469A2 (en) | 2015-09-21 | 2017-03-30 | Aptevo Research And Development Llc | Cd3 binding polypeptides |
| US10610585B2 (en) | 2017-09-26 | 2020-04-07 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods and compositions for treating and preventing HIV |
| MX2021003866A (es) | 2018-10-05 | 2021-09-08 | Xenotherapeutics Inc | Productos y metodos de xenotransplante. |
| US10883084B2 (en) | 2018-10-05 | 2021-01-05 | Xenotherapeutics, Inc. | Personalized cells, tissues, and organs for transplantation from a humanized, bespoke, designated-pathogen free, (non-human) donor and methods and products relating to same |
| CN113429481B (zh) * | 2021-07-07 | 2022-05-31 | 江苏农牧科技职业学院 | 一种靶向树突状细胞的纳米抗体分子及应用 |
| WO2023070317A1 (zh) * | 2021-10-26 | 2023-05-04 | 江苏省农业科学院 | 基于dc细胞的双功能纳米抗体及其构建方法和应用 |
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|---|---|---|---|---|
| US3865689A (en) * | 1972-11-09 | 1975-02-11 | Hoffmann La Roche | Method of producing carcinoembryonic antigens |
| US4446122A (en) * | 1979-12-28 | 1984-05-01 | Research Corporation | Purified human prostate antigen |
| US4331647A (en) * | 1980-03-03 | 1982-05-25 | Goldenberg Milton David | Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers |
| US4475196A (en) | 1981-03-06 | 1984-10-02 | Zor Clair G | Instrument for locating faults in aircraft passenger reading light and attendant call control system |
| US4474893A (en) * | 1981-07-01 | 1984-10-02 | The University of Texas System Cancer Center | Recombinant monoclonal antibodies |
| US4439196A (en) | 1982-03-18 | 1984-03-27 | Merck & Co., Inc. | Osmotic drug delivery system |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US5053224A (en) * | 1983-11-07 | 1991-10-01 | Hilary Koprowski | Induction of antibody response to solid tumors with anti-idiotype antibodies |
| MX9203291A (es) | 1985-06-26 | 1992-08-01 | Liposome Co Inc | Metodo para acoplamiento de liposomas. |
| US4954617A (en) * | 1986-07-07 | 1990-09-04 | Trustees Of Dartmouth College | Monoclonal antibodies to FC receptors for immunoglobulin G on human mononuclear phagocytes |
| US5260203A (en) * | 1986-09-02 | 1993-11-09 | Enzon, Inc. | Single polypeptide chain binding molecules |
| US4946778A (en) * | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| NZ222509A (en) * | 1986-11-19 | 1993-03-26 | Oncogen | Hybridoma cell line producing antibodies binding to tumour-associated mucin antigen |
| US5683674A (en) * | 1987-01-07 | 1997-11-04 | Imperial Cancer Research Technology Ltd. | Antibody against human mucin core protein and method of preparing and using same |
| ATE243754T1 (de) * | 1987-05-21 | 2003-07-15 | Micromet Ag | Multifunktionelle proteine mit vorbestimmter zielsetzung |
| GB8823869D0 (en) * | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5108921A (en) | 1989-04-03 | 1992-04-28 | Purdue Research Foundation | Method for enhanced transmembrane transport of exogenous molecules |
| AU656716B2 (en) * | 1989-09-15 | 1995-02-16 | Genetic Systems Corporation | Hybridoma CT43 producing a monoclonal antibody to a mucin epitope of colorectal cancer |
| US5165922A (en) * | 1990-05-22 | 1992-11-24 | Bristol-Myers Squibb Company | Synergistic tumor therapy with combinations of biologically active anti-tumor antibodies and chemotherapy |
| AU9040591A (en) | 1990-11-06 | 1992-05-26 | Children's Medical Center Corporation | Soluble mannose receptor peptides |
| GB9117522D0 (en) | 1991-08-14 | 1991-10-02 | Medical Res Council | Ligands for dendritic cells, their uses and production |
| DE4133791A1 (de) * | 1991-10-11 | 1993-04-15 | Behringwerke Ag | Monoklonale antikoerper gegen tumorassoziierte antigene, verfahren zu ihrer herstellung und ihre verwendung |
| AU8068694A (en) * | 1993-11-04 | 1995-05-23 | Canterbury Health Limited | Dendritic cell-specific antibodies and methods for their preparation |
| WO1995015340A1 (en) | 1993-12-03 | 1995-06-08 | The Board Of Trustees Of Leland Stanford Junior University | Monoclonal antibodies to antigens expressed by human dendritic cells |
| US20020187131A1 (en) * | 1995-01-31 | 2002-12-12 | Daniel Hawiger | Enhanced antigen delivery and modulation of the immune response therefrom |
| JPH10513350A (ja) | 1995-01-31 | 1998-12-22 | ザ ロックフェラー ユニヴァーシティ | DEC(樹状細胞及び上皮細胞、205 kDa)の同定、C型レクチンドメインを有するレセプター、DECをコードする核酸、及びこれらの使用 |
| US5773292A (en) * | 1995-06-05 | 1998-06-30 | Cornell University | Antibodies binding portions, and probes recognizing an antigen of prostate epithelial cells but not antigens circulating in the blood |
| US5869057A (en) * | 1995-06-07 | 1999-02-09 | Rock; Edwin P. | Recombinant vaccines to break self-tolerance |
| US6080409A (en) * | 1995-12-28 | 2000-06-27 | Dendreon Corporation | Immunostimulatory method |
| JP2000512490A (ja) | 1996-05-29 | 2000-09-26 | デレク ナイジェル ジョン ハート | 樹状細胞のレセプター |
| US5922845A (en) * | 1996-07-11 | 1999-07-13 | Medarex, Inc. | Therapeutic multispecific compounds comprised of anti-Fcα receptor antibodies |
| WO1998015579A1 (en) * | 1996-10-09 | 1998-04-16 | Canterbury Health Limited | Dendritic cell-specific antibodies |
| KR20010021597A (ko) * | 1997-07-09 | 2001-03-15 | 둘락 노먼 씨. | 분리된 덴드라이틱 세포막 단백질 유전자 |
| EP1027063B1 (en) | 1997-09-29 | 2009-02-18 | The Macfarlane Burnet Institute For Medical Research And Public Health Ltd | Mannose receptor bearing cell line and antigen composition |
| WO1999024554A2 (en) | 1997-11-12 | 1999-05-20 | University Of Pittsburgh | Isolation, characterization, and identification of dendritic like cells and methods of using same |
| CA2323083A1 (en) | 1998-03-17 | 1999-09-23 | Schering Corporation | Isolated mammalian membrane protein genes and related reagents |
| ES2230848T3 (es) | 1998-04-28 | 2005-05-01 | Smithkline Beecham Corporation | Anticuerpos monoclonales con inmunogenicidad reducida. |
| EP1078060B1 (en) | 1998-05-11 | 2007-01-10 | E.P. Prof. Dr. Rieber | Antibodies to dendritic cells and human dendritic cell populations and uses thereof |
| AU4954899A (en) | 1998-06-26 | 2000-01-17 | Trustees Of Dartmouth College | Methods and compositions for modulating antigen-specific immunological (humoral)responses by targeting such antigen to apcs in conjunction with anti-cd40 ligan d administration |
| KR100295558B1 (ko) | 1998-06-27 | 2001-07-12 | 김기태 | 1차면역세포들중덴드리틱세포(dendriticcell)표면에특이하게작용하는단클론항체3-6-a |
| EP0997476A3 (en) | 1998-09-25 | 2000-07-19 | Schering-Plough | Antibodies to a mammalian Langerhans cell antigen and their uses |
| EP1046651A1 (en) * | 1999-04-19 | 2000-10-25 | Koninklijke Universiteit Nijmegen | Composition and method for modulating dendritic cell-T interaction |
| KR100881471B1 (ko) | 2000-05-08 | 2009-02-05 | 셀덱스 쎄라퓨틱스, 인크. | 수상세포에 대한 인간 모노클로날 항체 |
-
2001
- 2001-05-08 KR KR1020067015862A patent/KR100881471B1/ko not_active Expired - Fee Related
- 2001-05-08 WO PCT/US2001/015114 patent/WO2001085798A2/en not_active Ceased
- 2001-05-08 CN CN018124909A patent/CN1452636B/zh not_active Expired - Fee Related
- 2001-05-08 EP EP01935275A patent/EP1282646B1/en not_active Expired - Lifetime
- 2001-05-08 DK DK01935275.6T patent/DK1282646T3/da active
- 2001-05-08 IL IL15265201A patent/IL152652A0/xx unknown
- 2001-05-08 US US09/851,614 patent/US7563876B2/en not_active Expired - Fee Related
- 2001-05-08 JP JP2001582397A patent/JP5007409B2/ja not_active Expired - Fee Related
- 2001-05-08 AU AU6138301A patent/AU6138301A/xx active Pending
- 2001-05-08 KR KR1020027014919A patent/KR100643818B1/ko not_active Expired - Fee Related
- 2001-05-08 AT AT01935275T patent/ATE553131T1/de active
- 2001-05-08 MX MXPA02010869A patent/MXPA02010869A/es active IP Right Grant
- 2001-05-08 CA CA002408594A patent/CA2408594A1/en not_active Abandoned
- 2001-05-08 AU AU2001261383A patent/AU2001261383B2/en not_active Ceased
- 2001-05-08 NZ NZ534864A patent/NZ534864A/en not_active IP Right Cessation
-
2002
- 2002-11-05 IL IL152652A patent/IL152652A/en not_active IP Right Cessation
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