JP2010505896A - アシルアミノイミダゾール類およびアシルアミノチアゾール類 - Google Patents
アシルアミノイミダゾール類およびアシルアミノチアゾール類 Download PDFInfo
- Publication number
- JP2010505896A JP2010505896A JP2009531766A JP2009531766A JP2010505896A JP 2010505896 A JP2010505896 A JP 2010505896A JP 2009531766 A JP2009531766 A JP 2009531766A JP 2009531766 A JP2009531766 A JP 2009531766A JP 2010505896 A JP2010505896 A JP 2010505896A
- Authority
- JP
- Japan
- Prior art keywords
- substituents
- alkyl
- bonded
- group
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 *C(CC1)(OC1=O)I Chemical compound *C(CC1)(OC1=O)I 0.000 description 2
- XCYNXKKVJGDZSD-UHFFFAOYSA-N CC(C)(C)OC(CC(C(O)=O)c(cc1)cc(OC)c1OC)=O Chemical compound CC(C)(C)OC(CC(C(O)=O)c(cc1)cc(OC)c1OC)=O XCYNXKKVJGDZSD-UHFFFAOYSA-N 0.000 description 1
- LHYPVPVUVYIWBX-VEDVMXKPSA-N CC(C)(C)OC(N([C@H](CC1)C(OC)=O)C1OC)=O Chemical compound CC(C)(C)OC(N([C@H](CC1)C(OC)=O)C1OC)=O LHYPVPVUVYIWBX-VEDVMXKPSA-N 0.000 description 1
- ODPABZBWIYZHLO-UHFFFAOYSA-N CC(C)N(CC(Nc1c(-c2ccccc2)nc(-c2ccc(F)[s]2)[nH]1)=O)C(C(CC(O)=O)c(cc1)cc(OC)c1OC)=O Chemical compound CC(C)N(CC(Nc1c(-c2ccccc2)nc(-c2ccc(F)[s]2)[nH]1)=O)C(C(CC(O)=O)c(cc1)cc(OC)c1OC)=O ODPABZBWIYZHLO-UHFFFAOYSA-N 0.000 description 1
- KXWSBFBTMSNEMW-UHFFFAOYSA-N CC(C)N(CC(Nc1c(-c2ccccc2)nc(-c2ccc(F)[s]2)[nH]1)=O)C(C(CCO)c(cc1)cc(OC)c1OC)=O Chemical compound CC(C)N(CC(Nc1c(-c2ccccc2)nc(-c2ccc(F)[s]2)[nH]1)=O)C(C(CCO)c(cc1)cc(OC)c1OC)=O KXWSBFBTMSNEMW-UHFFFAOYSA-N 0.000 description 1
- ZCDNBFSDXVLSHM-UHFFFAOYSA-N CC(CC1c(cc2OC)ccc2OC)N(CC(Nc2c(-c3ccccc3)nc(-c3ccc(F)[s]3)[nH]2)=O)C1=O Chemical compound CC(CC1c(cc2OC)ccc2OC)N(CC(Nc2c(-c3ccccc3)nc(-c3ccc(F)[s]3)[nH]2)=O)C1=O ZCDNBFSDXVLSHM-UHFFFAOYSA-N 0.000 description 1
- VUSXWPVCSGRKMO-UHFFFAOYSA-N N=C(c1ccccc1)SCc1ccccc1 Chemical compound N=C(c1ccccc1)SCc1ccccc1 VUSXWPVCSGRKMO-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/88—Nitrogen atoms, e.g. allantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102006048042A DE102006048042A1 (de) | 2006-10-11 | 2006-10-11 | Acylaminoimidazole und Acylaminothiazole |
| PCT/EP2007/008789 WO2008043533A2 (de) | 2006-10-11 | 2007-10-10 | Acylaminoimidazole und acylaminothiazole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2010505896A true JP2010505896A (ja) | 2010-02-25 |
Family
ID=39184814
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009531766A Pending JP2010505896A (ja) | 2006-10-11 | 2007-10-10 | アシルアミノイミダゾール類およびアシルアミノチアゾール類 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP2079708A2 (de) |
| JP (1) | JP2010505896A (de) |
| CA (1) | CA2666177A1 (de) |
| DE (1) | DE102006048042A1 (de) |
| WO (1) | WO2008043533A2 (de) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013118805A1 (ja) * | 2012-02-08 | 2013-08-15 | 大日本住友製薬株式会社 | ３位置換プロリン誘導体 |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2350002A1 (de) * | 2008-10-02 | 2011-08-03 | Abbott Laboratories | Neue verbindungen als kalziumkanalblocker |
| WO2011115813A1 (en) | 2010-03-18 | 2011-09-22 | Abbott Laboratories | Lactam acetamides as calcium channel blockers |
| IN2014MU00072A (de) * | 2014-01-08 | 2015-08-21 | Wockhardt Ltd | |
| IL277071B1 (en) | 2018-03-08 | 2024-03-01 | Incyte Corp | Aminopyrizine diol compounds as PI3K–y inhibitors |
| US11046658B2 (en) | 2018-07-02 | 2021-06-29 | Incyte Corporation | Aminopyrazine derivatives as PI3K-γ inhibitors |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2842523A1 (fr) * | 2002-07-17 | 2004-01-23 | Sanofi Synthelabo | Derives d'acylaminothiazole, leur preparation et leur application en therapeutique |
| RS50595B (sr) * | 2004-03-23 | 2010-05-07 | Pfizer Products Incorporated | Jedinjenja imidazola za lečenje neurodegenerativnih poremećaja |
| DE102006001574A1 (de) * | 2006-01-12 | 2007-07-19 | Bayer Healthcare Ag | Acylaminoimidazole |
-
2006
- 2006-10-11 DE DE102006048042A patent/DE102006048042A1/de not_active Withdrawn
-
2007
- 2007-10-10 WO PCT/EP2007/008789 patent/WO2008043533A2/de active Application Filing
- 2007-10-10 JP JP2009531766A patent/JP2010505896A/ja active Pending
- 2007-10-10 CA CA002666177A patent/CA2666177A1/en not_active Abandoned
- 2007-10-10 EP EP07818862A patent/EP2079708A2/de not_active Withdrawn
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013118805A1 (ja) * | 2012-02-08 | 2013-08-15 | 大日本住友製薬株式会社 | ３位置換プロリン誘導体 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008043533A2 (de) | 2008-04-17 |
| DE102006048042A1 (de) | 2008-04-17 |
| WO2008043533A3 (de) | 2008-07-03 |
| EP2079708A2 (de) | 2009-07-22 |
| CA2666177A1 (en) | 2008-04-17 |
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