JP2010504351A5 - - Google Patents
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- Publication number
- JP2010504351A5 JP2010504351A5 JP2009529369A JP2009529369A JP2010504351A5 JP 2010504351 A5 JP2010504351 A5 JP 2010504351A5 JP 2009529369 A JP2009529369 A JP 2009529369A JP 2009529369 A JP2009529369 A JP 2009529369A JP 2010504351 A5 JP2010504351 A5 JP 2010504351A5
- Authority
- JP
- Japan
- Prior art keywords
- phenyl
- benzazepine
- carbonyl
- spiro
- dihydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 CC=C(C1OC1*(CCC1(**CC1)C1)c2c1cc(C)cc2)C=C(C(*C(c1c(*)ccc(O)c1)=O)=I)S* Chemical compound CC=C(C1OC1*(CCC1(**CC1)C1)c2c1cc(C)cc2)C=C(C(*C(c1c(*)ccc(O)c1)=O)=I)S* 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82665406P | 2006-09-22 | 2006-09-22 | |
| PCT/US2007/078917 WO2008036755A1 (en) | 2006-09-22 | 2007-09-19 | Spiro benzazepines used as vasopressin antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010504351A JP2010504351A (ja) | 2010-02-12 |
| JP2010504351A5 true JP2010504351A5 (https=) | 2010-12-02 |
Family
ID=39030853
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009529369A Pending JP2010504351A (ja) | 2006-09-22 | 2007-09-19 | バソプレッシン拮抗薬として使用されるスピロベンズアゼピン類 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US7825110B2 (https=) |
| EP (1) | EP2078022B1 (https=) |
| JP (1) | JP2010504351A (https=) |
| CN (1) | CN101541806A (https=) |
| AT (1) | ATE532786T1 (https=) |
| AU (1) | AU2007299818B2 (https=) |
| CA (1) | CA2665849A1 (https=) |
| CY (1) | CY1112270T1 (https=) |
| DK (1) | DK2078022T3 (https=) |
| ES (1) | ES2374582T3 (https=) |
| PL (1) | PL2078022T3 (https=) |
| PT (1) | PT2078022E (https=) |
| SI (1) | SI2078022T1 (https=) |
| WO (1) | WO2008036755A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8921576B2 (en) | 2011-10-19 | 2014-12-30 | Kowa Company, Ltd. | Spiroindoline compound, and medicinal agent comprising same |
| BR112017000762A2 (pt) | 2014-07-15 | 2017-11-21 | Gruenenthal Gmbh | derivados de azaspiro(4.5)decano substituído. |
| TW201607923A (zh) | 2014-07-15 | 2016-03-01 | 歌林達有限公司 | 被取代之氮螺環（４．５）癸烷衍生物 |
| HK1251223A1 (en) | 2015-07-07 | 2019-01-25 | Japan Tobacco, Inc. | Method for producing 7h-pyrrolo[2, 3-d]pyrimidine derivative and intermediate thereof |
| AU2017384317C1 (en) | 2016-12-21 | 2022-06-30 | Japan Tobacco Inc. | PROCESS FOR PREPARING 7H-PYRROLO[2,3-d]PYRIMIDINE DERIVATIVES AND SYNTHETIC INTERMEDIATES THEREOF |
| WO2019055913A1 (en) * | 2017-09-15 | 2019-03-21 | Azevan Pharmaceuticals, Inc. | COMPOSITIONS AND METHODS FOR TREATMENT OF BRAIN INJURY |
| WO2019141575A1 (de) | 2018-01-16 | 2019-07-25 | Bayer Aktiengesellschaft | Unterstützung bei der behandlung von herzinsuffizienz |
| WO2022032073A2 (en) * | 2020-08-07 | 2022-02-10 | Casma Therapeutics, Inc. | Trpml modulators |
| JP7627343B2 (ja) * | 2020-11-26 | 2025-02-05 | シャンハイ ジェミンケア ファーマシューティカル カンパニー，リミティド | 新規ベンズアゼピンスピロ環式誘導体 |
| CN112939864B (zh) * | 2021-01-29 | 2022-05-06 | 中国医科大学 | 螺[苯并[c]氮杂-1,1’-环己基]-3-酮类化合物 |
| EP4491699A1 (de) | 2023-07-13 | 2025-01-15 | Klueber Lubrication München GmbH & Co. KG | Phthalimidverbindungen als basisöl für schmierstoffzusammensetzungen |
| WO2026002248A1 (zh) * | 2024-06-28 | 2026-01-02 | 上海济煜医药科技股份有限公司 | 作为v2受体拮抗剂的苯并氮杂卓并环衍生物 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4617302A (en) * | 1984-10-15 | 1986-10-14 | Eli Lilly And Company | Inotropic agents |
| DK0450097T3 (da) * | 1989-10-20 | 1996-05-20 | Otsuka Pharma Co Ltd | Benzoheterocykliske forbindelser |
| US5258510A (en) * | 1989-10-20 | 1993-11-02 | Otsuka Pharma Co Ltd | Benzoheterocyclic compounds |
| US5985869A (en) * | 1989-10-20 | 1999-11-16 | Otsuka Pharmaceutical Company, Limited | Benzoheterocyclic compounds |
| JP2905909B2 (ja) * | 1991-04-19 | 1999-06-14 | 大塚製薬株式会社 | バソプレシン拮抗剤 |
| FR2686878B1 (fr) * | 1992-01-30 | 1995-06-30 | Sanofi Elf | Derives du n-sulfonyl oxo-2 indole, leur preparation, les compositions pharmaceutiques en contenant. |
| US5686624A (en) * | 1992-01-30 | 1997-11-11 | Sanofi | 1-benzenesulfonyl-1,3-dihydro-indol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present |
| US5663431A (en) * | 1992-01-30 | 1997-09-02 | Sanofi | 1-benzenesulfonyl-1,3-dihydro-indol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present |
| FR2708605A1 (fr) * | 1993-07-30 | 1995-02-10 | Sanofi Sa | Dérivés du N-sulfonylindol-2-one, leur préparation, les compositions pharmaceutiques en contenant. |
| US5849780A (en) * | 1992-01-30 | 1998-12-15 | Sanofi | 1-benzenesulfonyl-1-1,3-dihydroindol-2-one derivatives, their preparation and pharmaceutical compositions in which they are present |
| JPH08502474A (ja) | 1992-10-07 | 1996-03-19 | メルク エンド カンパニー インコーポレーテッド | トコリティックオキシトシンレセプターアンタゴニスト |
| US5512563A (en) | 1993-07-29 | 1996-04-30 | American Cyanamid Company | Tricyclic benzazepine vasopressin antagonists |
| FR2708606B1 (fr) * | 1993-07-30 | 1995-10-27 | Sanofi Sa | Dérivés du N-phénylalkylindol-2-one, leur préparation, les compositions pharmaceutiques en contenant. |
| US5464788A (en) | 1994-03-24 | 1995-11-07 | Merck & Co., Inc. | Tocolytic oxytocin receptor antagonists |
| US5753648A (en) | 1995-01-17 | 1998-05-19 | American Cyanamid Company | Tricyclic benzazepine vasopressin antagonists |
| AUPP150098A0 (en) | 1998-01-27 | 1998-02-19 | Fujisawa Pharmaceutical Co., Ltd. | Benzamide derivatives |
| WO2002002531A1 (en) | 2000-07-05 | 2002-01-10 | Ortho-Mcneil Pharmaceutical, Inc. | Nonpeptide substituted spirobenzoazepines as vasopressin antagonists |
| AU2002231098A1 (en) * | 2000-12-15 | 2002-06-24 | Emory University | Nonpeptide agonists and antagonists of vasopressin receptors |
| US7011898B2 (en) * | 2003-03-21 | 2006-03-14 | Air Products And Chemicals, Inc. | Method of joining ITM materials using a partially or fully-transient liquid phase |
| AR044782A1 (es) * | 2003-06-17 | 2005-10-05 | Ortho Pharma Corp | Espirobenzazepinas sustituidas utiles como antagonistas de los receptores de vasopresina |
| EP1633721A1 (en) * | 2003-06-17 | 2006-03-15 | Janssen Pharmaceutica N.V. | Process for the preparation of nonpeptide substituted spirobenzoazepine derivatives |
| WO2007084591A2 (en) * | 2006-01-20 | 2007-07-26 | Janssen Pharmaceutica N.V. | Novel solid forms of (4r)-1-[4-(2-chloro-5-fluorobenzoyl)amino-3-methoxybenzoyl]-1,2,3,5-tetrahydro-spiro[4h-1-benzazepine-4,1'-[2]cyclopentene]-3'-carboxylic acid |
-
2007
- 2007-09-19 AT AT07842799T patent/ATE532786T1/de active
- 2007-09-19 SI SI200730800T patent/SI2078022T1/sl unknown
- 2007-09-19 DK DK07842799.4T patent/DK2078022T3/da active
- 2007-09-19 PL PL07842799T patent/PL2078022T3/pl unknown
- 2007-09-19 PT PT07842799T patent/PT2078022E/pt unknown
- 2007-09-19 EP EP07842799A patent/EP2078022B1/en active Active
- 2007-09-19 US US11/857,891 patent/US7825110B2/en not_active Expired - Fee Related
- 2007-09-19 WO PCT/US2007/078917 patent/WO2008036755A1/en not_active Ceased
- 2007-09-19 AU AU2007299818A patent/AU2007299818B2/en not_active Expired - Fee Related
- 2007-09-19 JP JP2009529369A patent/JP2010504351A/ja active Pending
- 2007-09-19 CA CA002665849A patent/CA2665849A1/en not_active Abandoned
- 2007-09-19 CN CNA2007800432003A patent/CN101541806A/zh active Pending
- 2007-09-19 ES ES07842799T patent/ES2374582T3/es active Active
-
2012
- 2012-01-24 CY CY20121100081T patent/CY1112270T1/el unknown
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