JP2010166921A5 - - Google Patents
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- Publication number
- JP2010166921A5 JP2010166921A5 JP2010044336A JP2010044336A JP2010166921A5 JP 2010166921 A5 JP2010166921 A5 JP 2010166921A5 JP 2010044336 A JP2010044336 A JP 2010044336A JP 2010044336 A JP2010044336 A JP 2010044336A JP 2010166921 A5 JP2010166921 A5 JP 2010166921A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- polypeptide
- amino acid
- acid sequence
- isolated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229920001184 polypeptide Polymers 0.000 claims 23
- 102000004196 processed proteins & peptides Human genes 0.000 claims 23
- 108090000765 processed proteins & peptides Proteins 0.000 claims 23
- 108091033319 polynucleotide Proteins 0.000 claims 18
- 239000002157 polynucleotide Substances 0.000 claims 18
- 102000040430 polynucleotide Human genes 0.000 claims 18
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 14
- 239000002773 nucleotide Substances 0.000 claims 12
- 125000003729 nucleotide group Chemical group 0.000 claims 12
- 125000003275 alpha amino acid group Chemical group 0.000 claims 11
- 239000000203 mixture Substances 0.000 claims 6
- 210000004027 cell Anatomy 0.000 claims 5
- 239000012634 fragment Substances 0.000 claims 5
- 230000000295 complement effect Effects 0.000 claims 3
- 239000013604 expression vector Substances 0.000 claims 3
- 230000028993 immune response Effects 0.000 claims 3
- 230000002163 immunogen Effects 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 229960005486 vaccine Drugs 0.000 claims 3
- 208000034762 Meningococcal Infections Diseases 0.000 claims 2
- 241000588650 Neisseria meningitidis Species 0.000 claims 2
- 238000012258 culturing Methods 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 108091026890 Coding region Proteins 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 239000012472 biological sample Substances 0.000 claims 1
- 239000001963 growth medium Substances 0.000 claims 1
- 238000009396 hybridization Methods 0.000 claims 1
- 230000001900 immune effect Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 244000005700 microbiome Species 0.000 claims 1
- 239000000523 sample Substances 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
- 210000001768 subcellular fraction Anatomy 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9810276.7A GB9810276D0 (en) | 1998-05-13 | 1998-05-13 | Novel compounds |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000548474A Division JP4707832B2 (ja) | 1998-05-13 | 1999-05-07 | 髄膜炎菌由来のｂａｓｂ０２９ポリヌクレオチドおよびポリペプチド |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010166921A JP2010166921A (ja) | 2010-08-05 |
| JP2010166921A5 true JP2010166921A5 (https=) | 2011-07-28 |
Family
ID=10831992
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000548474A Expired - Fee Related JP4707832B2 (ja) | 1998-05-13 | 1999-05-07 | 髄膜炎菌由来のｂａｓｂ０２９ポリヌクレオチドおよびポリペプチド |
| JP2010044336A Pending JP2010166921A (ja) | 1998-05-13 | 2010-03-01 | 髄膜炎菌由来のｂａｓｂ０２９ポリヌクレオチドおよびポリペプチド |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000548474A Expired - Fee Related JP4707832B2 (ja) | 1998-05-13 | 1999-05-07 | 髄膜炎菌由来のｂａｓｂ０２９ポリヌクレオチドおよびポリペプチド |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US6780419B1 (https=) |
| EP (2) | EP1078063B1 (https=) |
| JP (2) | JP4707832B2 (https=) |
| KR (4) | KR20100019461A (https=) |
| CN (1) | CN1322127C (https=) |
| AT (1) | ATE311457T1 (https=) |
| AU (1) | AU750032B2 (https=) |
| BR (1) | BR9910396A (https=) |
| CA (1) | CA2328403C (https=) |
| CY (1) | CY1105676T1 (https=) |
| CZ (1) | CZ299612B6 (https=) |
| DE (1) | DE69928658T2 (https=) |
| DK (1) | DK1078063T3 (https=) |
| ES (1) | ES2252946T3 (https=) |
| GB (1) | GB9810276D0 (https=) |
| HU (1) | HUP0102479A3 (https=) |
| IL (2) | IL139613A0 (https=) |
| NO (2) | NO326994B1 (https=) |
| NZ (1) | NZ508323A (https=) |
| PL (1) | PL197449B1 (https=) |
| TR (1) | TR200003347T2 (https=) |
| WO (1) | WO1999058683A2 (https=) |
| ZA (1) | ZA200006523B (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9726398D0 (en) * | 1997-12-12 | 1998-02-11 | Isis Innovation | Polypeptide and coding sequences |
| AU1979599A (en) * | 1998-01-14 | 1999-08-02 | Chiron S.P.A. | (neisseria meningitidis) antigens |
| GB9810276D0 (en) * | 1998-05-13 | 1998-07-15 | Smithkline Beecham Biolog | Novel compounds |
| JP4812942B2 (ja) | 1999-02-26 | 2011-11-09 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル | ＣＧモチーフを含むオリゴヌクレオチドを用いるＮｅｉｓｓｅｒｉａ抗原殺菌活性の増強 |
| GB9916529D0 (en) * | 1999-07-14 | 1999-09-15 | Chiron Spa | Antigenic peptides |
| RU2281956C2 (ru) | 1999-10-29 | 2006-08-20 | Чирон С.Р.Л. | Антигенные пептиды neisseria |
| GB9928196D0 (en) | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
| PT2289545T (pt) * | 2000-01-17 | 2016-09-06 | Glaxosmithkline Biologicals Sa | Vacina de omv suplementada contra meningococos |
| PL216780B1 (pl) * | 2000-01-25 | 2014-05-30 | Univ Queensland Of Santa Lucia | Wyizolowane białka zawierające konserwatywne obszary antygenu powierzchniowego NhhA z Neisseria meningitidis, białka fuzyjne, kompozycja farmaceutyczna, przeciwciało monoklonalne lub wiążący antygen fragment przeciwciała monoklonalnego, wyizolowany kwas nukleinowy, konstrukt ekspresyjny, komórka gospodarza, sposób wytwarzania rekombinowanego białka, sposób wykrywania N. meningitidis w próbce biologicznej, sposób diagnozowania zakażenia N. meningitidis oraz sposób wykrywania N. meningitidis w próbce biologicznej uzyskanej od pacjenta oraz zastosowanie wyizolowanego białka, białka fuzyjnego i konstruktu ekspresyjnego |
| ES2281409T3 (es) | 2000-02-28 | 2007-10-01 | Novartis Vaccines And Diagnostics S.R.L. | Expresion heterologa de proteinas de neisseria. |
| BR0211494A (pt) | 2001-07-27 | 2004-08-17 | Chiron Srl | Adesinas de meningococo nada, app e orf 40 |
| EP1524991A1 (en) | 2002-08-02 | 2005-04-27 | GlaxoSmithKline Biologicals S.A. | Vaccine composition comprising transferrin binding protein and hsf from gram negative bacteria |
| HUE031886T2 (en) | 2002-10-11 | 2017-08-28 | Glaxosmithkline Biologicals Sa | Polypeptide vaccines for extensive protection against hypervirulent meningococcal lines |
| CN103357002A (zh) | 2003-10-02 | 2013-10-23 | 诺华疫苗和诊断有限公司 | 多种脑膜炎球菌血清群的液体疫苗 |
| US7459930B2 (en) * | 2006-11-14 | 2008-12-02 | Micron Technology, Inc. | Digital calibration circuits, devices and systems including same, and methods of operation |
| GB0700562D0 (en) | 2007-01-11 | 2007-02-21 | Novartis Vaccines & Diagnostic | Modified Saccharides |
| GB0916570D0 (en) | 2009-09-21 | 2009-10-28 | Royal Holloway & Bedford New C | Method |
| EP2545068B8 (en) | 2010-03-11 | 2018-03-21 | GlaxoSmithKline Biologicals S.A. | Immunogenic composition or vaccine against gram-negative bacterial, for example neiserial, infection or disease |
| ES2642184T3 (es) * | 2012-01-05 | 2017-11-15 | Deutsches Krebsforschungszentrum | Péptidos para su uso en el tratamiento y diagnóstico de cánceres positivos a IDH1 R132H |
| ES2801054T3 (es) | 2016-07-27 | 2021-01-08 | Prysmian Spa | Cinta de fibra óptica flexible |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4769240A (en) * | 1980-09-15 | 1988-09-06 | Bactex, Inc. | Pili of neisseria and vaccine compositions containing same |
| US4702911A (en) * | 1985-09-27 | 1987-10-27 | Immunomed Corporation | Preparation of bacterium pili subunits and vaccines containing pili subunits |
| JPH01125328A (ja) | 1987-07-30 | 1989-05-17 | Centro Natl De Biopreparados | 髄膜炎菌ワクチン |
| FR2682041B1 (fr) * | 1991-10-03 | 1994-01-14 | Pasteur Merieux Serums Vaccins | Vaccin contre les infections a neisseria meningitidis. |
| US6245337B1 (en) * | 1994-08-25 | 2001-06-12 | Washington University | Haemophilus adherence and penetration proteins |
| US6121037A (en) * | 1994-10-18 | 2000-09-19 | Stojiljkovic; Igor | Bacterial hemoglobin receptor genes |
| US5646259A (en) * | 1995-03-24 | 1997-07-08 | St. Louis University | DNA encoding haemophilus adhesion proteins |
| US6265567B1 (en) * | 1995-04-07 | 2001-07-24 | University Of North Carolina At Chapel Hill | Isolated FrpB nucleic acid molecule |
| CU22559A1 (es) * | 1996-01-17 | 1999-05-03 | Ct Ingenieria Genetica Biotech | Sistema de expresión de antígenos heterologos en e. coli como proteínas de fusión |
| GB9726398D0 (en) * | 1997-12-12 | 1998-02-11 | Isis Innovation | Polypeptide and coding sequences |
| AU1979599A (en) * | 1998-01-14 | 1999-08-02 | Chiron S.P.A. | (neisseria meningitidis) antigens |
| GB9810276D0 (en) * | 1998-05-13 | 1998-07-15 | Smithkline Beecham Biolog | Novel compounds |
| JP2003518363A (ja) * | 1999-04-30 | 2003-06-10 | カイロン エセ．ピー．アー． | 保存されたナイセリア抗原 |
-
1998
- 1998-05-13 GB GBGB9810276.7A patent/GB9810276D0/en not_active Ceased
-
1999
- 1999-05-07 KR KR1020097024661A patent/KR20100019461A/ko not_active Ceased
- 1999-05-07 US US09/700,293 patent/US6780419B1/en not_active Expired - Lifetime
- 1999-05-07 AT AT99924946T patent/ATE311457T1/de active
- 1999-05-07 EP EP99924946A patent/EP1078063B1/en not_active Expired - Lifetime
- 1999-05-07 DE DE69928658T patent/DE69928658T2/de not_active Expired - Lifetime
- 1999-05-07 KR KR1020067009829A patent/KR100897951B1/ko not_active Expired - Fee Related
- 1999-05-07 NZ NZ508323A patent/NZ508323A/xx not_active IP Right Cessation
- 1999-05-07 IL IL13961399A patent/IL139613A0/xx unknown
- 1999-05-07 HU HU0102479A patent/HUP0102479A3/hu unknown
- 1999-05-07 DK DK99924946T patent/DK1078063T3/da active
- 1999-05-07 JP JP2000548474A patent/JP4707832B2/ja not_active Expired - Fee Related
- 1999-05-07 ES ES99924946T patent/ES2252946T3/es not_active Expired - Lifetime
- 1999-05-07 EP EP20050077297 patent/EP1621623A3/en not_active Withdrawn
- 1999-05-07 CZ CZ20004202A patent/CZ299612B6/cs not_active IP Right Cessation
- 1999-05-07 KR KR1020007012700A patent/KR100673674B1/ko not_active Expired - Fee Related
- 1999-05-07 WO PCT/EP1999/003255 patent/WO1999058683A2/en not_active Ceased
- 1999-05-07 TR TR2000/03347T patent/TR200003347T2/xx unknown
- 1999-05-07 BR BR9910396-6A patent/BR9910396A/pt not_active Application Discontinuation
- 1999-05-07 AU AU41420/99A patent/AU750032B2/en not_active Ceased
- 1999-05-07 PL PL345281A patent/PL197449B1/pl not_active IP Right Cessation
- 1999-05-07 CA CA2328403A patent/CA2328403C/en not_active Expired - Fee Related
- 1999-05-07 CN CNB998086061A patent/CN1322127C/zh not_active Expired - Fee Related
- 1999-05-07 KR KR1020087014761A patent/KR20080070073A/ko not_active Ceased
-
2000
- 2000-11-10 IL IL139613A patent/IL139613A/en not_active IP Right Cessation
- 2000-11-10 ZA ZA200006523A patent/ZA200006523B/xx unknown
- 2000-11-10 NO NO20005696A patent/NO326994B1/no not_active IP Right Cessation
-
2004
- 2004-07-22 US US10/896,778 patent/US20040265332A1/en not_active Abandoned
-
2006
- 2006-01-17 CY CY20061100057T patent/CY1105676T1/el unknown
-
2007
- 2007-12-07 US US11/999,978 patent/US20090093622A1/en not_active Abandoned
-
2009
- 2009-03-02 NO NO20090955A patent/NO20090955L/no not_active Application Discontinuation
-
2010
- 2010-03-01 JP JP2010044336A patent/JP2010166921A/ja active Pending
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