DE69928658T2 - Basb029 polynucleotide und polypeptide aus neisseria meningitis - Google Patents

Basb029 polynucleotide und polypeptide aus neisseria meningitis Download PDF

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Publication number
DE69928658T2
DE69928658T2 DE69928658T DE69928658T DE69928658T2 DE 69928658 T2 DE69928658 T2 DE 69928658T2 DE 69928658 T DE69928658 T DE 69928658T DE 69928658 T DE69928658 T DE 69928658T DE 69928658 T2 DE69928658 T2 DE 69928658T2
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DE
Germany
Prior art keywords
polypeptide
neisseria meningitis
basb029
basb029 polynucleotide
polypeptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69928658T
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English (en)
Other versions
DE69928658D1 (de
Inventor
Jean-Louis Ruelle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Biologicals SA
Original Assignee
GlaxoSmithKline Biologicals SA
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Publication date
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Application filed by GlaxoSmithKline Biologicals SA filed Critical GlaxoSmithKline Biologicals SA
Publication of DE69928658D1 publication Critical patent/DE69928658D1/de
Application granted granted Critical
Publication of DE69928658T2 publication Critical patent/DE69928658T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1217—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Plant Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
DE69928658T 1998-05-13 1999-05-07 Basb029 polynucleotide und polypeptide aus neisseria meningitis Expired - Lifetime DE69928658T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9810276.7A GB9810276D0 (en) 1998-05-13 1998-05-13 Novel compounds
PCT/EP1999/003255 WO1999058683A2 (en) 1998-05-13 1999-05-07 BASB029 POLYNUCLEOTIDE(S) AND POLYPEPTIDES FROM $i(NEISSERIA MENINGITIDIS)

Publications (2)

Publication Number Publication Date
DE69928658D1 DE69928658D1 (de) 2006-01-05
DE69928658T2 true DE69928658T2 (de) 2006-06-14

Family

ID=10831992

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69928658T Expired - Lifetime DE69928658T2 (de) 1998-05-13 1999-05-07 Basb029 polynucleotide und polypeptide aus neisseria meningitis

Country Status (24)

Country Link
US (3) US6780419B1 (de)
EP (2) EP1078063B1 (de)
JP (2) JP4707832B2 (de)
KR (4) KR100897951B1 (de)
CN (1) CN1322127C (de)
AT (1) ATE311457T1 (de)
AU (1) AU750032B2 (de)
BR (1) BR9910396A (de)
CA (1) CA2328403C (de)
CY (1) CY1105676T1 (de)
CZ (1) CZ299612B6 (de)
DE (1) DE69928658T2 (de)
DK (1) DK1078063T3 (de)
ES (1) ES2252946T3 (de)
GB (1) GB9810276D0 (de)
HK (1) HK1036300A1 (de)
HU (1) HUP0102479A3 (de)
IL (2) IL139613A0 (de)
NO (2) NO326994B1 (de)
NZ (1) NZ508323A (de)
PL (1) PL197449B1 (de)
TR (1) TR200003347T2 (de)
WO (1) WO1999058683A2 (de)
ZA (1) ZA200006523B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9726398D0 (en) 1997-12-12 1998-02-11 Isis Innovation Polypeptide and coding sequences
ATE446368T1 (de) † 1998-01-14 2009-11-15 Novartis Vaccines & Diagnostic Antigene aus neisseria meningitidis
GB9810276D0 (en) * 1998-05-13 1998-07-15 Smithkline Beecham Biolog Novel compounds
ES2228454T3 (es) 1999-02-26 2005-04-16 Chiron S.R.L. Mejora de la actividad bacteriana de antigenos de neisseria con oligonucleotidos que contienen motivos cg.
GB9916529D0 (en) * 1999-07-14 1999-09-15 Chiron Spa Antigenic peptides
CA2864069A1 (en) 1999-10-29 2001-05-03 Novartis Vaccines And Diagnostics S.R.L. Neisserial antigenic peptides
GB9928196D0 (en) 1999-11-29 2000-01-26 Chiron Spa Combinations of B, C and other antigens
ES2507100T3 (es) * 2000-01-17 2014-10-14 Novartis Vaccines And Diagnostics S.R.L. Vacuna OMV suplementada contra meningococo
US7947291B2 (en) * 2000-01-25 2011-05-24 The University Of Queensland Modified surface antigen
DK1790660T3 (da) 2000-02-28 2012-09-17 Novartis Vaccines & Diagnostic Heterolog ekspression af Neisseria-proteiner
MXPA04000653A (es) 2001-07-27 2004-11-22 Chiron Srl Adhesinas de meningococcus nada, app y orf 40.
PL399492A1 (pl) * 2002-08-02 2012-11-19 Glaxosmithkline Biologicals S.A. Szczepionka
JP4697706B2 (ja) 2002-10-11 2011-06-08 ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル 高毒性髄膜炎菌系統に対する広範な防御のためのポリペプチド−ワクチン
CN103405761A (zh) 2003-10-02 2013-11-27 诺华疫苗和诊断有限公司 多种脑膜炎球菌血清群的液体疫苗
US7459930B2 (en) * 2006-11-14 2008-12-02 Micron Technology, Inc. Digital calibration circuits, devices and systems including same, and methods of operation
GB0700562D0 (en) 2007-01-11 2007-02-21 Novartis Vaccines & Diagnostic Modified Saccharides
GB0916570D0 (en) 2009-09-21 2009-10-28 Royal Holloway & Bedford New C Method
EP3366696A1 (de) 2010-03-11 2018-08-29 GlaxoSmithKline Biologicals S.A. Impfstoff
MX349494B (es) * 2012-01-05 2017-08-01 Deutsches Krebsforsch Medios y metodos para tratar o diagnosticar canceres positivos a idh1 r132h mutante.
CN109642998B (zh) 2016-07-27 2020-05-15 普睿司曼股份公司 柔性光纤带

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4769240A (en) * 1980-09-15 1988-09-06 Bactex, Inc. Pili of neisseria and vaccine compositions containing same
US4702911A (en) * 1985-09-27 1987-10-27 Immunomed Corporation Preparation of bacterium pili subunits and vaccines containing pili subunits
JPH01125328A (ja) 1987-07-30 1989-05-17 Centro Natl De Biopreparados 髄膜炎菌ワクチン
FR2682041B1 (fr) * 1991-10-03 1994-01-14 Pasteur Merieux Serums Vaccins Vaccin contre les infections a neisseria meningitidis.
US6245337B1 (en) * 1994-08-25 2001-06-12 Washington University Haemophilus adherence and penetration proteins
US6121037A (en) * 1994-10-18 2000-09-19 Stojiljkovic; Igor Bacterial hemoglobin receptor genes
US5646259A (en) * 1995-03-24 1997-07-08 St. Louis University DNA encoding haemophilus adhesion proteins
US6265567B1 (en) * 1995-04-07 2001-07-24 University Of North Carolina At Chapel Hill Isolated FrpB nucleic acid molecule
CU22559A1 (es) * 1996-01-17 1999-05-03 Ct Ingenieria Genetica Biotech Sistema de expresión de antígenos heterologos en e. coli como proteínas de fusión
GB9726398D0 (en) * 1997-12-12 1998-02-11 Isis Innovation Polypeptide and coding sequences
ATE446368T1 (de) * 1998-01-14 2009-11-15 Novartis Vaccines & Diagnostic Antigene aus neisseria meningitidis
GB9810276D0 (en) * 1998-05-13 1998-07-15 Smithkline Beecham Biolog Novel compounds
DK1228217T3 (da) * 1999-04-30 2013-02-25 Novartis Vaccines & Diagnostic Konserverede neisseria-antigener

Also Published As

Publication number Publication date
DK1078063T3 (da) 2006-04-03
KR20060076789A (ko) 2006-07-04
IL139613A (en) 2014-03-31
TR200003347T2 (tr) 2001-06-21
WO1999058683A2 (en) 1999-11-18
DE69928658D1 (de) 2006-01-05
HK1036300A1 (en) 2001-12-28
AU4142099A (en) 1999-11-29
PL197449B1 (pl) 2008-03-31
CZ20004202A3 (en) 2001-05-16
CA2328403C (en) 2013-11-05
CZ299612B6 (cs) 2008-09-17
JP2010166921A (ja) 2010-08-05
ATE311457T1 (de) 2005-12-15
CN1322127C (zh) 2007-06-20
WO1999058683A9 (en) 2002-05-02
NZ508323A (en) 2002-10-25
CA2328403A1 (en) 1999-11-18
WO1999058683A3 (en) 2000-04-06
HUP0102479A3 (en) 2004-10-28
NO20090955L (no) 2001-01-11
EP1621623A3 (de) 2009-02-18
EP1078063B1 (de) 2005-11-30
JP2002514424A (ja) 2002-05-21
EP1621623A2 (de) 2006-02-01
KR20010043571A (ko) 2001-05-25
IL139613A0 (en) 2002-02-10
CY1105676T1 (el) 2010-12-22
NO20005696L (no) 2001-01-11
CN1309707A (zh) 2001-08-22
NO20005696D0 (no) 2000-11-10
ES2252946T3 (es) 2006-05-16
GB9810276D0 (en) 1998-07-15
US20090093622A1 (en) 2009-04-09
HUP0102479A2 (hu) 2001-10-28
US20040265332A1 (en) 2004-12-30
KR20080070073A (ko) 2008-07-29
BR9910396A (pt) 2001-10-30
JP4707832B2 (ja) 2011-06-22
NO326994B1 (no) 2009-03-30
PL345281A1 (en) 2001-12-03
EP1078063A2 (de) 2001-02-28
AU750032B2 (en) 2002-07-11
KR100673674B1 (ko) 2007-01-23
KR100897951B1 (ko) 2009-05-18
KR20100019461A (ko) 2010-02-18
ZA200006523B (en) 2001-11-12
US6780419B1 (en) 2004-08-24

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