JP2009545527A - 粘膜炎の治療用の組成物及び方法 - Google Patents

粘膜炎の治療用の組成物及び方法 Download PDF

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Publication number
JP2009545527A
JP2009545527A JP2009520828A JP2009520828A JP2009545527A JP 2009545527 A JP2009545527 A JP 2009545527A JP 2009520828 A JP2009520828 A JP 2009520828A JP 2009520828 A JP2009520828 A JP 2009520828A JP 2009545527 A JP2009545527 A JP 2009545527A
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formula
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Japanese (ja)
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JP2009545527A5 (enExample
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シー・エリック・シュワルツ
ペール・グヨルストラップ
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Resolvyx Pharmaceuticals Inc
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Resolvyx Pharmaceuticals Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2009520828A 2006-07-19 2007-07-19 粘膜炎の治療用の組成物及び方法 Pending JP2009545527A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83186606P 2006-07-19 2006-07-19
PCT/US2007/016338 WO2008011085A1 (en) 2006-07-19 2007-07-19 Compositions and methods for the treatment of mucositis

Publications (2)

Publication Number Publication Date
JP2009545527A true JP2009545527A (ja) 2009-12-24
JP2009545527A5 JP2009545527A5 (enExample) 2010-09-09

Family

ID=38617335

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009520828A Pending JP2009545527A (ja) 2006-07-19 2007-07-19 粘膜炎の治療用の組成物及び方法

Country Status (14)

Country Link
US (1) US20100035989A1 (enExample)
EP (1) EP2049099A1 (enExample)
JP (1) JP2009545527A (enExample)
KR (1) KR20090040323A (enExample)
CN (1) CN101528218A (enExample)
AU (1) AU2007275658B2 (enExample)
BR (1) BRPI0714562A2 (enExample)
CA (1) CA2658361C (enExample)
IL (1) IL196465A0 (enExample)
MX (1) MX2009000657A (enExample)
RU (1) RU2009101324A (enExample)
SG (1) SG173397A1 (enExample)
WO (1) WO2008011085A1 (enExample)
ZA (1) ZA200900388B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011500568A (ja) * 2007-10-12 2011-01-06 リゾルヴィクス・ファーマシューティカルズ・インコーポレイテッド 眼病治療のための組成物及び方法
WO2015111701A1 (ja) * 2014-01-24 2015-07-30 国立大学法人京都大学 希少脂肪酸を含む抗炎症剤

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* Cited by examiner, † Cited by third party
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CN1202068C (zh) 2000-02-16 2005-05-18 布里格姆及妇女医院股份有限公司 阿司匹林触发的脂质介体
US8481772B2 (en) * 2002-04-01 2013-07-09 University Of Southern California Trihydroxy polyunsaturated eicosanoid derivatives
US7902257B2 (en) * 2002-04-01 2011-03-08 University Of Southern California Trihydroxy polyunsaturated eicosanoid
US20100190735A1 (en) * 2006-03-28 2010-07-29 Myrex Pharmaceuticals Inc. Mouthwash and Method of Using Same for the Treatment of Mucositis or Stomatitis
EP2180787B1 (en) 2007-08-01 2013-10-30 University of Pittsburgh - Of the Commonwealth System of Higher Education Nitro oleic acid modulation of type ii diabetes
EP2280928B1 (en) 2008-05-01 2018-07-25 Complexa Inc. Vinyl substituted fatty acids
WO2009155439A2 (en) 2008-06-19 2009-12-23 University Of Utah Research Foundation Use of nitrated lipids for treatment of side effects of toxic medical therapies
US20140024713A1 (en) 2008-06-19 2014-01-23 University Of Utah Research Foundation Use of nitrated lipids for treatment of side effects of toxic medical therapies
US20120122816A1 (en) * 2009-02-05 2012-05-17 Resolvyx Pharmaceuticals, Inc. Compositions and methods for organ preservation
EP2415748A4 (en) 2009-02-20 2013-08-07 Univ Tokyo NEW INFLAMMATORY COMPOUNDS
US9066902B2 (en) 2009-07-31 2015-06-30 University of Pittsburgh—of the Commonwealth System of Higher Education Fatty acids as anti-inflammatory agents
WO2011041639A2 (en) 2009-10-02 2011-04-07 Miller Raymond A Heteroatom containing substituted fatty acids
EP2744491B1 (en) 2011-08-19 2020-07-29 The University of Utah Research Foundation Combination therapy with nitrated lipids and inhibitors of the renin-angiotensin-aldosterone system
CA2863765A1 (en) * 2012-02-03 2013-08-08 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Fatty acids as anti-inflammatory agents
CN103417471A (zh) * 2012-05-22 2013-12-04 吴升华 一种治疗湿疹等皮肤炎症的脂氧素乳膏
EP3037090B1 (en) 2013-08-19 2019-07-31 Enzychem Lifesciences Corporation Composition containing monoacetyldiglyceride compound as active ingredient for preventing or treating rheumatoid arthritis
KR20180015297A (ko) 2014-05-15 2018-02-12 주식회사 엔지켐생명과학 백혈구 감소증 및 혈소판 감소증에 대한 치료 방법
US10513524B2 (en) 2015-07-07 2019-12-24 H. Lundbeck A/S PDE9 inhibitors with imidazo triazinone backbone and imidazo pyrazinone backbone for treatment of peripheral diseases
CN108430466A (zh) 2015-10-02 2018-08-21 康普莱克夏公司 使用治疗有效量的活化脂肪酸预防、治疗和逆转疾病
US9808438B2 (en) * 2015-11-09 2017-11-07 Enzychem Lifesciences Corporation Method for treating mucositis
JP2021526134A (ja) 2018-05-25 2021-09-30 イマラ インク． ６−［（３Ｓ，４Ｓ）−４−メチル−ｌ−（ピリミジン−２−イルメチル）ピロリジン−３−イル］−３−テトラヒドロピラン−４−イル−７Ｈ−イミダゾ［ｌ，５−Ａ］ピラジン−８−オンの一水和物および結晶形態
KR20250108770A (ko) 2018-08-31 2025-07-15 카듀리온 파마슈티칼스, 인크. 겸상 세포 질환의 치료를 위한 pde9 억제제

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4576758A (en) * 1984-06-01 1986-03-18 The Upjohn Company Anti-inflammatory lipoxin B analogs
US6887901B1 (en) * 1993-06-15 2005-05-03 Brigham & Women's Hospital, Inc. Lipoxin compounds and their use in treating cell proliferative disorders
CA2645558C (en) * 1999-03-18 2012-05-15 Brigham And Women's Hospital Regulation of phospholipase d activity
CN1202068C (zh) * 2000-02-16 2005-05-18 布里格姆及妇女医院股份有限公司 阿司匹林触发的脂质介体
AU2001249329A1 (en) * 2000-03-20 2001-10-03 Brigham And Women's Hospital Lipoxin analogs and methods for the treatment of periodontal disease
US6627658B2 (en) * 2001-03-02 2003-09-30 The Brigham And Women's Hospital Lipoxin analogs as novel inhibitors of angiogenesis
EP1453819A2 (en) * 2001-12-03 2004-09-08 Novozymes A/S Statin-like compounds
WO2003051350A1 (en) * 2001-12-18 2003-06-26 The Brigham And Women's Hospital Use of lipoxin analogs to promote cell defense against gram-negative infections
WO2003053423A2 (en) * 2001-12-18 2003-07-03 The Brigham And Women's Hospital Inhibition or prevention of infection by bacteria with epa, dha or analogs
US7582785B2 (en) * 2002-04-01 2009-09-01 University Of Southern California Trihydroxy polyunsaturated eicosanoid derivatives
SI2022775T1 (sl) * 2002-04-01 2015-03-31 University Of Southern California Trihidroksi polinenasiäśeni eikosanoidi
US7378444B2 (en) * 2002-06-17 2008-05-27 Brigham And Women's Hospital, Inc. Analogues of lipid mediators derived from omega-3 PUFAs and methods of use
EP3584235A3 (en) * 2002-08-12 2020-04-22 Brigham and Women's Hospital Resolvins: biotemplates for novel therapeutic interventions
US7759395B2 (en) * 2002-08-12 2010-07-20 The Brigham And Women's Hospital, Inc. Use of docosatrienes, resolvins and their stable analogs in the treatment of airway diseases and asthma
US20050113443A1 (en) * 2003-06-01 2005-05-26 Karp Christopher L. Modulation of airway inflammation in patients with cystic fibrosis and related diseases
US20050203184A1 (en) * 2003-09-10 2005-09-15 Petasis Nicos A. Benzo lipoxin analogues
AU2005306320B2 (en) * 2004-11-19 2011-09-08 Martek Biosciences Corporation Oxylipins from long chain polyunsaturated fatty acids and methods of making and using the same
US20060293288A1 (en) * 2005-01-07 2006-12-28 Serhan Charles N Use of resolvins to treat gastrointestinal diseases

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011500568A (ja) * 2007-10-12 2011-01-06 リゾルヴィクス・ファーマシューティカルズ・インコーポレイテッド 眼病治療のための組成物及び方法
JP2014037437A (ja) * 2007-10-12 2014-02-27 Resolvyx Pharmaceuticals Inc 眼病治療のための組成物及び方法
WO2015111701A1 (ja) * 2014-01-24 2015-07-30 国立大学法人京都大学 希少脂肪酸を含む抗炎症剤
JPWO2015111701A1 (ja) * 2014-01-24 2017-03-23 国立大学法人京都大学 希少脂肪酸を含む抗炎症剤
JP2020097565A (ja) * 2014-01-24 2020-06-25 国立大学法人京都大学 希少脂肪酸を含む抗炎症剤

Also Published As

Publication number Publication date
ZA200900388B (en) 2010-03-31
CN101528218A (zh) 2009-09-09
SG173397A1 (en) 2011-08-29
RU2009101324A (ru) 2010-07-27
WO2008011085A1 (en) 2008-01-24
IL196465A0 (en) 2009-11-18
CA2658361A1 (en) 2008-01-24
AU2007275658A1 (en) 2008-01-24
BRPI0714562A2 (pt) 2013-04-02
US20100035989A1 (en) 2010-02-11
KR20090040323A (ko) 2009-04-23
EP2049099A1 (en) 2009-04-22
MX2009000657A (es) 2009-05-28
AU2007275658B2 (en) 2011-09-01
CA2658361C (en) 2013-04-23

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