JP2009544734A5 - - Google Patents

Download PDF

Info

Publication number
JP2009544734A5
JP2009544734A5 JP2009521989A JP2009521989A JP2009544734A5 JP 2009544734 A5 JP2009544734 A5 JP 2009544734A5 JP 2009521989 A JP2009521989 A JP 2009521989A JP 2009521989 A JP2009521989 A JP 2009521989A JP 2009544734 A5 JP2009544734 A5 JP 2009544734A5
Authority
JP
Japan
Prior art keywords
composition
antagonist
alkyl
substituted
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2009521989A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009544734A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2007/074351 external-priority patent/WO2008014338A2/en
Publication of JP2009544734A publication Critical patent/JP2009544734A/ja
Publication of JP2009544734A5 publication Critical patent/JP2009544734A5/ja
Pending legal-status Critical Current

Links

JP2009521989A 2006-07-25 2007-07-25 目の障害の予防および処置のための内皮分化遺伝子ファミリー3(edg−3、s1p3)レセプターのアンタゴニスト Pending JP2009544734A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83308006P 2006-07-25 2006-07-25
PCT/US2007/074351 WO2008014338A2 (en) 2006-07-25 2007-07-25 Antagonists of endothelial differentiation gene subfamily 3 (edg-3, s1p3) receptors for prevention and treatment of ocular disorders

Publications (2)

Publication Number Publication Date
JP2009544734A JP2009544734A (ja) 2009-12-17
JP2009544734A5 true JP2009544734A5 (https=) 2011-03-10

Family

ID=38982306

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009521989A Pending JP2009544734A (ja) 2006-07-25 2007-07-25 目の障害の予防および処置のための内皮分化遺伝子ファミリー3(edg−3、s1p3)レセプターのアンタゴニスト

Country Status (11)

Country Link
US (2) US20080025973A1 (https=)
EP (1) EP2068856A2 (https=)
JP (1) JP2009544734A (https=)
KR (1) KR20090033886A (https=)
CN (1) CN101505744A (https=)
AU (1) AU2007279311A1 (https=)
BR (1) BRPI0714593A2 (https=)
CA (1) CA2657480A1 (https=)
MX (1) MX2009000907A (https=)
WO (1) WO2008014338A2 (https=)
ZA (1) ZA200900316B (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101014329B (zh) 2004-07-16 2010-09-08 杏林制药株式会社 用于对器官或组织的移植的排异反应或骨髓移植的移植物抗宿主反应预防或治疗的药物组合物
EP1806338B1 (en) 2004-10-12 2016-01-20 Kyorin Pharmaceutical Co., Ltd. Process for producing 2-amino-2-[2-[4-(3-benzyloxy-phenylthio)-2-chlorophenyl[ethyl]-1,3-propanediol hydrochloride and hydrates thereof. and intermediates the production thereof
SI1932522T1 (sl) * 2005-10-07 2012-08-31 Kyorin Seiyaku Kk Terapevtsko sredstvo za jetrno bolezen, ki vsebuje 2-amino-1,3- propandiolni derivat kot aktivno sestavino
TWI389683B (zh) * 2006-02-06 2013-03-21 Kyorin Seiyaku Kk A therapeutic agent for an inflammatory bowel disease or an inflammatory bowel disease treatment using a 2-amino-1,3-propanediol derivative as an active ingredient
MX2009001457A (es) * 2006-08-08 2009-02-19 Kyorin Seiyaku Kk Derivados de aminoalcohol e inmunosupresores que contienen lo mismo como ingrediente activo.
JP5188972B2 (ja) * 2006-08-08 2013-04-24 杏林製薬株式会社 アミノリン酸エステル誘導体及びそれらを有効成分とするs1p受容体調節剤
WO2009099174A1 (ja) 2008-02-07 2009-08-13 Kyorin Pharmaceutical Co., Ltd. アミノアルコール誘導体を有効成分とする炎症性腸疾患の治療剤又は予防剤
WO2009117335A2 (en) * 2008-03-17 2009-09-24 Allergan, Inc. S1p3 receptor inhibitors for treating inflammation
US20120071448A1 (en) * 2009-05-05 2012-03-22 Allergan, Inc. S1P3 Receptor Inhibitors for Treating Conditions of the Eye
US20110039900A1 (en) * 2009-08-11 2011-02-17 Allergan, Inc. Isothiozoles for treating conditions of the eye
BR112012006965A2 (pt) * 2009-09-30 2017-08-29 Stiefel Res Australia Pty Ltd Cosmético sob a forma de espuma
CN102146411B (zh) * 2011-01-06 2013-01-02 中国人民解放军第三军医大学第三附属医院 新型双功能抗瘢痕和组织纤维化寡聚核苷酸药物

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8107694A (en) * 1993-11-17 1995-06-06 Byk Nederland Bv Use of substituted thiazolidine derivatives in the treatment of raised intraocular pressure
US5545626A (en) * 1994-01-19 1996-08-13 The Trustees Of Columbia University In The City Of New York Method of treating glaucoma with oligonucleotides
US5750652A (en) * 1994-01-21 1998-05-12 Yale University Deltex proteins
WO2001058468A1 (en) * 2000-02-09 2001-08-16 Connetics Corporation Use of relaxin to treat diseases related to vasoconstriction
JP2001261575A (ja) * 2000-03-13 2001-09-26 General Hospital Corp 血管収縮を調節する方法とその組成物
JP2002332278A (ja) * 2001-05-08 2002-11-22 Human Science Shinko Zaidan Edg受容体拮抗作用を有する複素環誘導体
WO2003092584A2 (en) * 2002-04-30 2003-11-13 Alcon, Inc. Agents which regulate, inhibit, or modulate the activity and/or expression of connective tissue growth factor (ctgf) as a unique means to both lower intraocular pressure and treat glaucomatous retinopathies/optic neuropathies
CA2533587A1 (en) * 2002-07-30 2004-02-05 University Of Virginia Patent Foundation Compounds active in sphingosine 1-phosphate signaling
AU2003258433A1 (en) * 2002-08-28 2004-03-19 Merck Frosst Canada Ltd Oxazolidin-2-one and thiazolidin-2-one derivatives for use as ep4 receptor agonists in the treatment of glaucoma
FR2845003A1 (fr) * 2002-09-30 2004-04-02 Merck Sante Sas Utilisation de derives de thiazolidinedione comme inhibiteurs de l'aldose reductase
CN100418948C (zh) * 2003-07-15 2008-09-17 麦克公司 羟基吡啶cgrp受体抗拮抗剂
JP2005247691A (ja) * 2004-03-01 2005-09-15 Toa Eiyo Ltd S1p3受容体拮抗薬
JP2008522977A (ja) * 2004-12-06 2008-07-03 ユニバーシティ オブ バージニア パテント ファンデーション スフィンゴシン=1−リン酸のアリールアミドアナログ
US8546452B2 (en) * 2005-10-12 2013-10-01 Toa Eiyo Ltd. S1P3 receptor antagonist
CN101460458A (zh) * 2006-02-15 2009-06-17 阿勒根公司 具有1-磷酸-鞘氨醇(s1p)受体拮抗剂生物活性的带芳基或者杂芳基基团的吲哚-3-羧酸的酰胺、酯、硫代酰胺和硫羟酸酯化合物

Similar Documents

Publication Publication Date Title
JP2009544734A5 (https=)
AU2025271125A1 (en) Methods for treating or preventing ophthalmological conditions
EP2262476B1 (en) Drug delivery to the anterior and posterior segments of the eye using eye drops.
US20080025973A1 (en) Antagonists of endothelial differentiation gene subfamily 3 (edg-3, s1p3) receptors for prevention and treatment of ocular disorders
DE60307607D1 (de) Verwendung von selektiven ep4 rezeptor agonisten zur behandlung von krankheiten
IL308752B2 (en) RNAi factors, compositions and methods of using them for treating transthyretin-related diseases
WO2010125416A1 (en) Drug delivery to the anterior and posterior segments of the eye
JP2023099171A (ja) 緑内障を治療するためのWnt5aの調節
JP2014516029A5 (ja) Rgシステイン酸ペプチドを含む治療剤
JP2017524012A (ja) 眼科症状を処置するまたは予防するための方法
JP2006516957A (ja) Il−6アンタゴニストの抗血管形成用途
JP7474706B2 (ja) 4-フェニル酪酸を含有する老視の治療または予防剤
EP3747471A1 (en) Medicine for preventing or treating ophthalmic disease associated with enhanced intraocular neovascularization and/or intraocular vascular permeability
JP2020505365A (ja) 治療用および神経保護用ペプチド
JPWO2001017527A1 (ja) 眼疾患の予防、治療剤
EP2598117A2 (en) Preservative free bimatoprost solutions
CN1450897A (zh) 用于控制iop并治疗青光眼的5ht2兴奋剂
JP5911866B2 (ja) 病的血管新生に関連する病気を予防し、安定させかつ/または阻害するための注射可能な医薬組成物
WO2014138018A1 (en) Preservative free bimatoprost and timolol solutions
JP2013501794A (ja) 目の疾患を治療するためのイソチオゾール
O'Brien et al. Metastatic Staphylococcus aureus endophthalmitis: a case report.
EP4574146A1 (en) Dhp-i inhibitors for use as neuroprotectants and in the treatment of neuroinflammatory diseases
JP7641902B2 (ja) 緑内障の新規治療法
RU2023125207A (ru) СРЕДСТВА ДЛЯ РНКи, КОМПОЗИЦИИ И СПОСОБЫ ИХ ПРИМЕНЕНИЯ ДЛЯ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЙ, АССОЦИИРОВАННЫХ С ТРАНСТИРЕТИНОМ (TTR)
JPWO2020180865A5 (https=)