JP2009543541A5 - - Google Patents
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- Publication number
- JP2009543541A5 JP2009543541A5 JP2008558403A JP2008558403A JP2009543541A5 JP 2009543541 A5 JP2009543541 A5 JP 2009543541A5 JP 2008558403 A JP2008558403 A JP 2008558403A JP 2008558403 A JP2008558403 A JP 2008558403A JP 2009543541 A5 JP2009543541 A5 JP 2009543541A5
- Authority
- JP
- Japan
- Prior art keywords
- urp
- protein
- amino acids
- module
- binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 235000018102 proteins Nutrition 0.000 claims 34
- 102000004169 proteins and genes Human genes 0.000 claims 34
- 108090000623 proteins and genes Proteins 0.000 claims 34
- 150000001413 amino acids Chemical class 0.000 claims 27
- 235000001014 amino acid Nutrition 0.000 claims 25
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims 12
- 238000000034 method Methods 0.000 claims 12
- 230000027455 binding Effects 0.000 claims 10
- 210000002966 serum Anatomy 0.000 claims 7
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 claims 6
- 239000004471 Glycine Substances 0.000 claims 6
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 claims 6
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 claims 6
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 claims 6
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 claims 6
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 claims 6
- 239000004473 Threonine Substances 0.000 claims 6
- 235000004279 alanine Nutrition 0.000 claims 6
- 235000003704 aspartic acid Nutrition 0.000 claims 6
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 claims 6
- 210000004027 cell Anatomy 0.000 claims 6
- 235000013922 glutamic acid Nutrition 0.000 claims 6
- 239000004220 glutamic acid Substances 0.000 claims 6
- 229920000642 polymer Polymers 0.000 claims 6
- 108091033319 polynucleotide Proteins 0.000 claims 5
- 102000040430 polynucleotide Human genes 0.000 claims 5
- 239000002157 polynucleotide Substances 0.000 claims 5
- 239000012636 effector Substances 0.000 claims 4
- 238000010348 incorporation Methods 0.000 claims 4
- 230000003252 repetitive effect Effects 0.000 claims 4
- 230000028327 secretion Effects 0.000 claims 4
- 102000004506 Blood Proteins Human genes 0.000 claims 3
- 108010017384 Blood Proteins Proteins 0.000 claims 3
- 210000004899 c-terminal region Anatomy 0.000 claims 2
- 230000015556 catabolic process Effects 0.000 claims 2
- 238000006731 degradation reaction Methods 0.000 claims 2
- 238000000338 in vitro Methods 0.000 claims 2
- 230000009871 nonspecific binding Effects 0.000 claims 2
- 108091026890 Coding region Proteins 0.000 claims 1
- BWGNESOTFCXPMA-UHFFFAOYSA-N Dihydrogen disulfide Chemical compound SS BWGNESOTFCXPMA-UHFFFAOYSA-N 0.000 claims 1
- 102000004310 Ion Channels Human genes 0.000 claims 1
- 102000018697 Membrane Proteins Human genes 0.000 claims 1
- 108010052285 Membrane Proteins Proteins 0.000 claims 1
- 108010061100 Nucleoproteins Proteins 0.000 claims 1
- 102000011931 Nucleoproteins Human genes 0.000 claims 1
- 210000004978 chinese hamster ovary cell Anatomy 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 235000018417 cysteine Nutrition 0.000 claims 1
- 150000001945 cysteines Chemical class 0.000 claims 1
- 230000001086 cytosolic effect Effects 0.000 claims 1
- 239000003145 cytotoxic factor Substances 0.000 claims 1
- 230000002950 deficient Effects 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 210000003527 eukaryotic cell Anatomy 0.000 claims 1
- 230000001747 exhibiting effect Effects 0.000 claims 1
- 239000001963 growth medium Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 210000001236 prokaryotic cell Anatomy 0.000 claims 1
- 238000001542 size-exclusion chromatography Methods 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74341006P | 2006-03-06 | 2006-03-06 | |
| US74362206P | 2006-03-21 | 2006-03-21 | |
| US11/528,927 US20070191272A1 (en) | 2005-09-27 | 2006-09-27 | Proteinaceous pharmaceuticals and uses thereof |
| US11/528,950 US20070212703A1 (en) | 2005-09-27 | 2006-09-27 | Proteinaceous pharmaceuticals and uses thereof |
| PCT/US2007/005952 WO2007103515A2 (en) | 2006-03-06 | 2007-03-06 | Unstructured recombinant polymers and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013018187A Division JP2013081481A (ja) | 2006-03-06 | 2013-02-01 | 非構造組換えポリマーおよびその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009543541A JP2009543541A (ja) | 2009-12-10 |
| JP2009543541A5 true JP2009543541A5 (enExample) | 2010-04-22 |
Family
ID=40278652
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008558381A Pending JP2009528844A (ja) | 2006-03-06 | 2007-03-06 | 遺伝子パッケージおよびその使用 |
| JP2008558403A Withdrawn JP2009543541A (ja) | 2006-03-06 | 2007-03-06 | 非構造組換えポリマーおよびその使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008558381A Pending JP2009528844A (ja) | 2006-03-06 | 2007-03-06 | 遺伝子パッケージおよびその使用 |
Country Status (2)
| Country | Link |
|---|---|
| JP (2) | JP2009528844A (enExample) |
| CA (1) | CA2644548A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113366009B (zh) * | 2018-11-27 | 2025-02-11 | 科纳科学控股有限公司 | 用于生物合成大麻素的双向多酶支架 |
| JP2023501515A (ja) * | 2019-11-12 | 2023-01-18 | テクニッシェ ウニヴェルズィテート ミュンヘン | ヒトＩＬ－２７αサブユニットの均質ムテイン |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002507393A (ja) * | 1998-02-11 | 2002-03-12 | マキシジェン， インコーポレイテッド | 抗原ライブラリー免疫 |
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2007
- 2007-03-06 JP JP2008558381A patent/JP2009528844A/ja active Pending
- 2007-03-06 JP JP2008558403A patent/JP2009543541A/ja not_active Withdrawn
- 2007-03-06 CA CA002644548A patent/CA2644548A1/en not_active Abandoned