JP2016500250A5 - - Google Patents
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- JP2016500250A5 JP2016500250A5 JP2015543148A JP2015543148A JP2016500250A5 JP 2016500250 A5 JP2016500250 A5 JP 2016500250A5 JP 2015543148 A JP2015543148 A JP 2015543148A JP 2015543148 A JP2015543148 A JP 2015543148A JP 2016500250 A5 JP2016500250 A5 JP 2016500250A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- protein
- modified protein
- acid residues
- reference secreted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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- 125000000539 amino acid group Chemical group 0.000 claims 28
- 102000004169 proteins and genes Human genes 0.000 claims 24
- 108090000623 proteins and genes Proteins 0.000 claims 24
- 102000035118 modified proteins Human genes 0.000 claims 23
- 108091005573 modified proteins Proteins 0.000 claims 23
- 235000020776 essential amino acid Nutrition 0.000 claims 16
- 239000003797 essential amino acid Substances 0.000 claims 16
- 238000006467 substitution reaction Methods 0.000 claims 11
- 150000001413 amino acids Chemical class 0.000 claims 9
- 150000007523 nucleic acids Chemical class 0.000 claims 7
- 244000005700 microbiome Species 0.000 claims 5
- 239000000203 mixture Substances 0.000 claims 5
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 4
- 229940024606 amino acid Drugs 0.000 claims 4
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 3
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 239000004475 Arginine Substances 0.000 claims 2
- AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 claims 2
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 claims 2
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 claims 2
- KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 claims 2
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims 2
- 230000029087 digestion Effects 0.000 claims 2
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 210000003205 muscle Anatomy 0.000 claims 2
- -1 Ile amino acid Chemical class 0.000 claims 1
- KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 claims 1
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 claims 1
- 239000004472 Lysine Substances 0.000 claims 1
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 claims 1
- 239000004473 Threonine Substances 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 210000004051 gastric juice Anatomy 0.000 claims 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 claims 1
- AGPKZVBTJJNPAG-UHFFFAOYSA-N isoleucine Natural products CCC(C)C(N)C(O)=O AGPKZVBTJJNPAG-UHFFFAOYSA-N 0.000 claims 1
- 229960000310 isoleucine Drugs 0.000 claims 1
- 235000016709 nutrition Nutrition 0.000 claims 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 claims 1
- 239000004474 valine Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261728427P | 2012-11-20 | 2012-11-20 | |
| US61/728,427 | 2012-11-20 | ||
| PCT/US2013/071091 WO2014081884A1 (en) | 2012-11-20 | 2013-11-20 | Engineered secreted proteins and methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016500250A JP2016500250A (ja) | 2016-01-12 |
| JP2016500250A5 true JP2016500250A5 (enExample) | 2017-01-19 |
Family
ID=50776536
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015543148A Withdrawn JP2016500250A (ja) | 2012-11-20 | 2013-11-20 | 改変された分泌タンパク質及び方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20150307562A1 (enExample) |
| EP (1) | EP2922416A4 (enExample) |
| JP (1) | JP2016500250A (enExample) |
| CN (1) | CN104936466A (enExample) |
| CA (1) | CA2892021A1 (enExample) |
| HK (1) | HK1214739A1 (enExample) |
| WO (1) | WO2014081884A1 (enExample) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105452476B (zh) | 2013-05-31 | 2020-08-14 | 帝斯曼知识产权资产管理有限公司 | 用于二萜生产的微生物 |
| AU2014296573A1 (en) | 2013-07-29 | 2016-02-18 | Danisco Us Inc. | Variant enzymes |
| JP2016537302A (ja) * | 2013-09-25 | 2016-12-01 | アクセラ・ヘルス・インコーポレイテッドＡｘｃｅｌｌａ Ｈｅａｌｔｈ Ｉｎｃ． | グルコースおよびカロリーの制限における、糖尿病および肥満の予防および処置のための組成物および配合物、ならびにその生成方法および使用方法 |
| GB201401699D0 (en) * | 2014-01-31 | 2014-03-19 | Dupont Nutrition Biosci Aps | Protein |
| CN103881994B (zh) * | 2014-04-14 | 2020-03-27 | 中国农业科学院生物技术研究所 | 一种具有高转糖苷活性的β-半乳糖苷酶突变体及其制备方法和应用 |
| FR3022558B1 (fr) * | 2014-06-20 | 2019-01-25 | Proteus | Variants d'exoglucanases a activite amelioree et leurs utilisations |
| LT3197472T (lt) * | 2014-09-22 | 2021-11-10 | Tanea Medical Ab | Rekombinantinių baltymų be fenilalanino naudojimas gydant fenilketonuriją |
| EP3201214A4 (en) * | 2014-10-01 | 2018-04-04 | Ansun Biopharma, Inc. | Ecotin variants |
| HK1244185A1 (zh) * | 2014-11-11 | 2018-08-03 | Clara Foods Co. | 用於生成卵清蛋白的方法和组合物 |
| BR112017011271A2 (pt) | 2014-12-19 | 2018-04-03 | Novozymes As | composição, polipeptídeo isolado, aditivo de ração animal, ração animal, métodos de melhoria de um ou mais parâmetros de desempenho de um animal, de solubilização de xilose de material à base de plantas, de liberação de amido de material à base de plantas, de melhoria do valor nutricional de uma ração animal, de preparação de uma ração animal e de produção do polipeptídeo, uso de uma composição, polinucleotídeo, construto de ácido nucleico ou vetor de expressão, e, célula hospedeira recombinante. |
| GB201501565D0 (en) * | 2015-01-30 | 2015-03-18 | Dupont Nutrition Biosci Aps | Method |
| US20180243392A1 (en) * | 2015-03-17 | 2018-08-30 | Vanderbilt University | Cs21 and lnga protein vaccines |
| EP3313193B1 (en) * | 2015-06-26 | 2021-03-24 | Novozymes A/S | Method for producing a coffee extract |
| US10188135B2 (en) * | 2015-11-04 | 2019-01-29 | Stokley-Van Camp, Inc. | Method for inducing satiety |
| US11167016B2 (en) | 2016-02-18 | 2021-11-09 | Amanoenzyme Inc. | Intestinal flora improvement agent |
| AU2017270269A1 (en) * | 2016-05-24 | 2018-11-15 | Novozymes A/S | Compositions comprising polypeptides having galactanase activity and polypeptides having beta-galactosidase activity |
| US10808268B2 (en) | 2016-05-24 | 2020-10-20 | Novozymes A/S | Polypeptides having alpha-galactosidase activity and polynucleotides encoding same |
| WO2017202979A1 (en) * | 2016-05-24 | 2017-11-30 | Novozymes A/S | Polypeptides having alpha-galactosidase activity and polynucleotides encoding same |
| WO2018005035A1 (en) | 2016-06-27 | 2018-01-04 | Novozymes A/S | Method of dewatering post fermentation fluids |
| BR112019000089A2 (pt) * | 2016-07-08 | 2019-07-09 | Novozymes As | variante de xilanase, composição, grânulo, aditivo de ração animal, formulação líquida, ração animal, métodos para aprimorar um ou mais parâmetros de desempenho de um animal, para solubilizar xilana a partir do material à base de planta, para liberar amido do material à base de planta, para aprimorar o valor nutricional de uma ração animal, para preparar uma massa ou um produto assado preparado a partir da massa, de produção de uma variante de xilanase e para obter uma variante de xilanase, uso de uma variante de xilanase, processo de produção de um produto de fermentação, polinucleotídeo isolado, construto de ácido nucleico ou vetor de expressão, e, célula hospedeira recombinante. |
| JP6845244B2 (ja) * | 2016-07-19 | 2021-03-17 | サントリーホールディングス株式会社 | モグロールまたはモグロール配糖体の生産方法 |
| PL3290436T3 (pl) | 2016-09-01 | 2020-01-31 | Metax Institut Für Diätetik Gmbh | Białko wolne od fenyloalaniny do leczenia pku |
| EA201891926A1 (ru) * | 2017-02-03 | 2019-04-30 | Киверди, Инк. | Микроорганизмы и искусственные экосистемы для производства белка, продуктов питания и полезных побочных продуктов из субстратов c1 |
| EP3592429A1 (en) * | 2017-03-06 | 2020-01-15 | DuPont Nutrition Biosciences ApS | Novel fungal fucosidases and their use in preventing and/or treating a pathogenic infection in an animal |
| EP3840582A4 (en) * | 2018-08-21 | 2022-08-03 | Clara Foods Co. | MODIFICATION OF PROTEIN GLYCOSYLATION IN MICROORGANISMS |
| CA3118924A1 (en) | 2018-11-09 | 2020-05-14 | Ginkgo Bioworks, Inc. | Biosynthesis of mogrosides |
| US20220169999A1 (en) * | 2019-03-19 | 2022-06-02 | Bayer Cropscience Lp | Fusion proteins, recombinant bacteria, and exosporium fragements for plant health |
| EP4613765A1 (en) | 2019-07-11 | 2025-09-10 | Clara Foods Co. | Protein compositions and consumable products thereof |
| US12096784B2 (en) | 2019-07-11 | 2024-09-24 | Clara Foods Co. | Protein compositions and consumable products thereof |
| US10927360B1 (en) | 2019-08-07 | 2021-02-23 | Clara Foods Co. | Compositions comprising digestive enzymes |
| EP4031661A1 (en) | 2019-09-16 | 2022-07-27 | Novozymes A/S | Polypeptides having beta-glucanase activity and polynucleotides encoding same |
| WO2021185969A1 (en) * | 2020-03-18 | 2021-09-23 | Numaferm Gmbh | Variants of hlya and uses thereof |
| EP3892290A1 (en) * | 2020-04-08 | 2021-10-13 | NUMAFERM GmbH | Variants of hlya and uses thereof |
| WO2021207679A1 (en) * | 2020-04-10 | 2021-10-14 | Liberty Biosecurity, Llc | Polypeptide compositions and uses thereof |
| EP4291634A4 (en) * | 2021-02-10 | 2025-01-01 | Novozymes A/S | POLYPEPTIDES HAVING PECTINASE ACTIVITY, POLYNUCLEOTIDES FOR ENCODING THEM AND USES THEREOF |
| WO2022204576A1 (en) * | 2021-03-25 | 2022-09-29 | Bio-Cat, Inc. | Fungal protease mixtures and uses thereof |
| CN114015678A (zh) * | 2021-09-30 | 2022-02-08 | 中南民族大学 | 一种球形赖氨酸芽孢杆菌C3-41来源的氨肽酶Amp0279及其重组菌株和应用 |
| MX2021014268A (es) * | 2021-11-19 | 2022-02-16 | Univ Mexico Nac Autonoma | Proteina optimizada que comprende los aminoacidos esenciales para la nutricion humana. |
| US20230281444A1 (en) * | 2022-03-04 | 2023-09-07 | Cella Farms Inc | Computational system and algorithm for selecting nutritional microorganisms based on in silico protein quality determination |
| CA3253720A1 (en) | 2022-04-20 | 2023-10-26 | Novozymes As | PROCESS FOR PRODUCING FREE FATTY ACIDS |
| EP4519287A1 (en) * | 2022-05-04 | 2025-03-12 | Locus Biosciences, Inc. | Phage compositions for escherichia comprising crispr-cas systems and methods of use thereof |
| CN119630280A (zh) | 2022-05-14 | 2025-03-14 | 诺维信公司 | 用于预防、处理、抑制和/或消除植物病原性侵染和感染的组合物和方法 |
| CN115160420B (zh) * | 2022-06-24 | 2023-06-02 | 西南大学 | 盔形毕赤酵母scp类分泌蛋白及其应用 |
| WO2024220717A1 (en) * | 2023-04-20 | 2024-10-24 | Ginkgo Bioworks, Inc. | Biosynthesis of mogrosides |
| WO2025155915A1 (en) * | 2024-01-17 | 2025-07-24 | Anagram Therapeutics, Inc. | Methods and compositions for treating congenital sucrase-isomaltase deficiency |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6800726B1 (en) * | 1996-11-01 | 2004-10-05 | Pioneer Hi-Bred International, Inc. | Proteins with increased levels of essential amino acids |
| AR017831A1 (es) * | 1997-12-10 | 2001-10-24 | Pioneer Hi Bred Int | Metodo para alterar la composicion de aminoacidos de una proteina nativa de interes, proteina elaborada, y polinucleotido |
| US20060159724A1 (en) * | 2000-08-08 | 2006-07-20 | Bell Stacey J | Nutritional supplement for the management of weight |
| CN100537600C (zh) * | 2001-09-17 | 2009-09-09 | 孟山都技术公司 | 增强型蛋白及其应用方法 |
| US7273738B2 (en) * | 2002-10-01 | 2007-09-25 | Novozymes A/S | Family GH-61 polypeptides |
| CN1557475A (zh) * | 2004-02-04 | 2004-12-29 | 高春平 | 美容、减肥营养组合物 |
| EP2327316B1 (en) * | 2009-11-29 | 2016-11-16 | Premier Nutrition Corporation | Method of enhancing muscle protein synthesis |
| US20110191903A1 (en) * | 2009-12-31 | 2011-08-04 | Pioneer Hi-Bred International, Inc. | Engineering plant resistance to diseases caused by pathogens |
| WO2012128260A1 (ja) * | 2011-03-24 | 2012-09-27 | 旭硝子株式会社 | シゾサッカロミセス属酵母の形質転換体、該形質転換体の製造方法、β－グルコシダーゼの製造方法、およびセルロースの分解方法 |
| BR112014023869A2 (pt) * | 2012-03-26 | 2017-07-18 | Pronutria Inc | proteínas nutritivas carregadas e métodos |
-
2013
- 2013-11-20 HK HK16102843.7A patent/HK1214739A1/zh unknown
- 2013-11-20 EP EP13856957.9A patent/EP2922416A4/en not_active Withdrawn
- 2013-11-20 CN CN201380070852.1A patent/CN104936466A/zh active Pending
- 2013-11-20 JP JP2015543148A patent/JP2016500250A/ja not_active Withdrawn
- 2013-11-20 CA CA2892021A patent/CA2892021A1/en not_active Abandoned
- 2013-11-20 WO PCT/US2013/071091 patent/WO2014081884A1/en not_active Ceased
- 2013-11-20 US US14/443,773 patent/US20150307562A1/en not_active Abandoned
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