MD3290436T2 - Proteină fără fenilalanină pentru tratamentul fenilcetonuriei - Google Patents
Proteină fără fenilalanină pentru tratamentul fenilcetonurieiInfo
- Publication number
- MD3290436T2 MD3290436T2 MDE20180783T MD3290436T2 MD 3290436 T2 MD3290436 T2 MD 3290436T2 MD E20180783 T MDE20180783 T MD E20180783T MD 3290436 T2 MD3290436 T2 MD 3290436T2
- Authority
- MD
- Moldova
- Prior art keywords
- protein
- phenylalanine
- pku
- treatment
- dietary
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 102000015781 Dietary Proteins Human genes 0.000 abstract 3
- 108010010256 Dietary Proteins Proteins 0.000 abstract 3
- 235000021245 dietary protein Nutrition 0.000 abstract 3
- 235000018102 proteins Nutrition 0.000 abstract 3
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 abstract 2
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 abstract 2
- 238000009825 accumulation Methods 0.000 abstract 1
- 230000035508 accumulation Effects 0.000 abstract 1
- 235000007882 dietary composition Nutrition 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 235000013305 food Nutrition 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/195—Proteins from microorganisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/54—Proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Food Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Polymers & Plastics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- General Preparation And Processing Of Foods (AREA)
- Soy Sauces And Products Related Thereto (AREA)
Abstract
Invenţia se referă la o proteină dietetică recombinantă, care nu conţine fenilalanină şi este o proteină dietetică cu o valoare biologică ridicată. Sunt furnizate în continuare un vector care codifică respectiva proteină dietetică, un microorganism care exprimă respectiva proteină, o metodă pentru producerea respectivei proteine şi o compoziţie dietetică cuprinzând respectiva proteină care, într-o formă de realizare, este utilizată ca medicament şi / sau aliment pentru scopuri medicale speciale la pacienţii cu acumulări de fenilalanină în organism.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16186895.5A EP3290436B1 (en) | 2016-09-01 | 2016-09-01 | Phenylalanine-free protein for the treatment of pku |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MD3290436T2 true MD3290436T2 (ro) | 2019-10-31 |
Family
ID=56883591
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDE20180783 MD3290436T2 (ro) | 2016-09-01 | 2016-09-01 | Proteină fără fenilalanină pentru tratamentul fenilcetonuriei |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US10640538B2 (ro) |
| EP (1) | EP3290436B1 (ro) |
| JP (1) | JP6954676B2 (ro) |
| CN (1) | CN109661401B (ro) |
| AU (1) | AU2017317652B2 (ro) |
| BR (1) | BR112019004270A2 (ro) |
| CA (1) | CA3033271C (ro) |
| CY (1) | CY1121886T1 (ro) |
| DK (1) | DK3290436T3 (ro) |
| ES (1) | ES2742175T3 (ro) |
| HR (1) | HRP20191406T1 (ro) |
| HU (1) | HUE044665T2 (ro) |
| IL (1) | IL265015B2 (ro) |
| LT (1) | LT3290436T (ro) |
| MA (1) | MA43352B1 (ro) |
| MD (1) | MD3290436T2 (ro) |
| ME (1) | ME03510B (ro) |
| MX (1) | MX2019002422A (ro) |
| NZ (1) | NZ750498A (ro) |
| PL (1) | PL3290436T3 (ro) |
| PT (1) | PT3290436T (ro) |
| RU (1) | RU2764796C2 (ro) |
| SA (1) | SA519401175B1 (ro) |
| SI (1) | SI3290436T1 (ro) |
| UA (1) | UA124630C2 (ro) |
| WO (1) | WO2018041920A1 (ro) |
| ZA (1) | ZA201901505B (ro) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113264988B (zh) * | 2019-09-27 | 2022-12-06 | 湖北康肽药业有限公司 | 一组特殊膳食蛋白质 |
| CN110747218A (zh) * | 2019-09-27 | 2020-02-04 | 深圳市诺维健生物技术有限责任公司 | 一种特殊膳食蛋白质的生产方法与应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04126051A (ja) * | 1990-09-18 | 1992-04-27 | Snow Brand Milk Prod Co Ltd | フェニルケトン尿症患者用栄養調製物 |
| GB9310472D0 (en) | 1993-05-20 | 1993-07-07 | Univ Warwick | Phenylalanine-free protein and dna coding thereof |
| GB9314802D0 (en) * | 1993-07-16 | 1993-08-25 | Pharmaceutical Proteins Ltd | Modified proteins |
| WO1996017064A1 (en) | 1994-12-02 | 1996-06-06 | Indiana University Foundation | Phenylalanine free proteins |
| EP1092769B1 (de) * | 1999-10-15 | 2008-10-29 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Polypeptid-Tag's für den Nachweis und die Aufreinigung von Polypeptiden |
| AU2002234561B2 (en) * | 2000-12-07 | 2007-01-18 | Dsm Ip Assets B.V. | Protein hydrolysates enriched in peptides having a carboxy terminal proline residue |
| US9034402B2 (en) * | 2007-04-16 | 2015-05-19 | Solae, Llc | Protein hydrolysate compositions having improved sensory characteristics and physical properties |
| KR101530395B1 (ko) | 2007-04-27 | 2015-06-19 | 피페넥스 인크. | 향상된 수율 및(또는) 품질로 이종 단백질을 발현하는 특정 균주를 동정하기 위해 미생물 숙주를 신속히 스크리닝하는 방법 |
| US20100316623A1 (en) * | 2009-04-23 | 2010-12-16 | Andrew Turner | Phenylalanine hydroxylase fusion protein and methods for treating phenylketonuria |
| WO2013133691A1 (en) * | 2012-03-09 | 2013-09-12 | N.V. Nutricia | Liquid nutritional composition comprising free amino acids |
| EP2831097A4 (en) | 2012-03-26 | 2016-01-20 | Pronutria Inc | NUTRIENT PROTEINS AND FRAGMENTS COMPRISING LITTLE OR NO PHENYLALANINE AND METHODS |
| CA2892021A1 (en) | 2012-11-20 | 2014-05-30 | Pronutria, Inc. | Engineered secreted proteins and methods |
| EP3197472B1 (en) | 2014-09-22 | 2021-08-04 | Tanea Medical AB | Recombinant phe-free proteins for use in the treatment of phenylketonuria |
-
2016
- 2016-09-01 MA MA43352A patent/MA43352B1/fr unknown
- 2016-09-01 ES ES16186895T patent/ES2742175T3/es active Active
- 2016-09-01 ME MEP-2019-208A patent/ME03510B/me unknown
- 2016-09-01 PT PT16186895T patent/PT3290436T/pt unknown
- 2016-09-01 MD MDE20180783 patent/MD3290436T2/ro unknown
- 2016-09-01 DK DK16186895.5T patent/DK3290436T3/da active
- 2016-09-01 PL PL16186895T patent/PL3290436T3/pl unknown
- 2016-09-01 EP EP16186895.5A patent/EP3290436B1/en active Active
- 2016-09-01 LT LTEP16186895.5T patent/LT3290436T/lt unknown
- 2016-09-01 HU HUE16186895 patent/HUE044665T2/hu unknown
- 2016-09-01 SI SI201630331T patent/SI3290436T1/sl unknown
-
2017
- 2017-08-30 NZ NZ750498A patent/NZ750498A/en unknown
- 2017-08-30 CN CN201780053903.8A patent/CN109661401B/zh active Active
- 2017-08-30 MX MX2019002422A patent/MX2019002422A/es unknown
- 2017-08-30 RU RU2019109142A patent/RU2764796C2/ru active
- 2017-08-30 WO PCT/EP2017/071814 patent/WO2018041920A1/en active Application Filing
- 2017-08-30 CA CA3033271A patent/CA3033271C/en active Active
- 2017-08-30 JP JP2019512755A patent/JP6954676B2/ja active Active
- 2017-08-30 US US16/329,027 patent/US10640538B2/en active Active
- 2017-08-30 UA UAA201903097A patent/UA124630C2/uk unknown
- 2017-08-30 IL IL265015A patent/IL265015B2/en unknown
- 2017-08-30 AU AU2017317652A patent/AU2017317652B2/en active Active
- 2017-08-30 BR BR112019004270A patent/BR112019004270A2/pt unknown
-
2019
- 2019-02-24 SA SA519401175A patent/SA519401175B1/ar unknown
- 2019-03-11 ZA ZA2019/01505A patent/ZA201901505B/en unknown
- 2019-08-02 HR HRP20191406 patent/HRP20191406T1/hr unknown
- 2019-08-08 CY CY20191100853T patent/CY1121886T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2019011215A (es) | Ácidos nucleicos que codifican proteínas asociadas a crispr y usos de los mismos. | |
| MX2018014573A (es) | Vacuna contra el virus del zika. | |
| MX2017010576A (es) | Maltooligosacaridos ricos en fibra que tienen baja biodisponibilidad de glucosa, procedimiento de fabricacion de los mismos y uso de los mismos en alimentos para humanos y piensos para animales. | |
| WO2017200659A3 (en) | A method to enhance wound healing using silk-derived protein | |
| EP3747457A3 (en) | Factor 1 protein, factor 2 protein and inhibitors thereof for use in treating or preventing diseases | |
| MX2023000796A (es) | Composicion farmaceutica, metodos para tratamiento y sus usos. | |
| MX2018004616A (es) | Cosmetica qie tiene bacterias probioticas. | |
| EA202191753A1 (ru) | Синтетические и рекомбинантно полученные коллагеновые пептиды, имеющие биологическую активность | |
| MX2018002546A (es) | Composiciones que comprenden un compuesto de urolitina. | |
| MX2018008644A (es) | Derivados de 3-((hetero)aril)-alquil-8-amino-2-oxo-1,3-diaza-espir o-[4.5]-decano. | |
| MX2022003758A (es) | Composiciones para el cuidado bucal que comprenden acido beta de lupulo y aminoacido. | |
| AU2018326364A1 (en) | Methods of enhancing and/or stabilizing cardiac function in patients with Fabry disease | |
| MX2017008454A (es) | Peptidos y su uso en el tratamiento de la piel. | |
| CR20220249A (es) | Derivados terapéuticos de interleucina-22 | |
| MX2017011169A (es) | Uso de citrato ferrico en el tratamiento de anemia por deficiencia de hierro. | |
| WO2017121646A8 (en) | 3-(carboxyethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives | |
| MX2018008643A (es) | Derivados de 3-((hetero)aril)-8-amino-2-oxo-1,3-diaza-espiro-[4.5] -decano. | |
| MD3290436T2 (ro) | Proteină fără fenilalanină pentru tratamentul fenilcetonuriei | |
| WO2018060528A3 (en) | Therapeutic protein | |
| MX2017001433A (es) | Sistema de bioprocesamiento a microescala y metodo para fabricacion de proteina a partir de sangre humana. | |
| WO2014045065A3 (en) | Dietary compositions and their uses | |
| MX2016002359A (es) | Suplemento antienvejecimiento. | |
| Ricco et al. | Statement from the European Society of Vascular Surgery and the World Federation of Vascular Surgery Societies: Transatlantic Inter-Society Consensus Document (TASC) III and International Standards for Vascular Care (ISVaC) | |
| WO2019040459A3 (en) | Composition and nutritional supplement made therefrom | |
| WO2019150050A8 (fr) | Dimères de variants du facteur x |