JP2009542678A5 - - Google Patents
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- Publication number
- JP2009542678A5 JP2009542678A5 JP2009518301A JP2009518301A JP2009542678A5 JP 2009542678 A5 JP2009542678 A5 JP 2009542678A5 JP 2009518301 A JP2009518301 A JP 2009518301A JP 2009518301 A JP2009518301 A JP 2009518301A JP 2009542678 A5 JP2009542678 A5 JP 2009542678A5
- Authority
- JP
- Japan
- Prior art keywords
- disintegrant
- api
- ratio
- tablet
- dissolution rate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81782106P | 2006-06-30 | 2006-06-30 | |
| US60/817,821 | 2006-06-30 | ||
| PCT/US2007/015168 WO2008005353A2 (en) | 2006-06-30 | 2007-06-29 | Immediate-release tablet formulations of a thrombin receptor antagonist |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012082021A Division JP2012126752A (ja) | 2006-06-30 | 2012-03-30 | トロンビン受容体拮抗薬の即放性錠剤製剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009542678A JP2009542678A (ja) | 2009-12-03 |
| JP2009542678A5 true JP2009542678A5 (https=) | 2010-05-13 |
| JP5116764B2 JP5116764B2 (ja) | 2013-01-09 |
Family
ID=38895141
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009518301A Expired - Fee Related JP5116764B2 (ja) | 2006-06-30 | 2007-06-29 | トロンビン受容体拮抗薬の即放性錠剤製剤 |
| JP2012082021A Withdrawn JP2012126752A (ja) | 2006-06-30 | 2012-03-30 | トロンビン受容体拮抗薬の即放性錠剤製剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012082021A Withdrawn JP2012126752A (ja) | 2006-06-30 | 2012-03-30 | トロンビン受容体拮抗薬の即放性錠剤製剤 |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US20080031943A1 (https=) |
| EP (2) | EP2491922B1 (https=) |
| JP (2) | JP5116764B2 (https=) |
| KR (1) | KR20090023670A (https=) |
| CN (2) | CN104922054A (https=) |
| AR (1) | AR061790A1 (https=) |
| AU (1) | AU2007269733B2 (https=) |
| BR (1) | BRPI0713935A2 (https=) |
| CA (1) | CA2656395C (https=) |
| CL (1) | CL2007001923A1 (https=) |
| CO (1) | CO6150126A2 (https=) |
| ES (2) | ES2616405T3 (https=) |
| MX (1) | MX2009000131A (https=) |
| NO (1) | NO20090467L (https=) |
| PE (1) | PE20080376A1 (https=) |
| TW (1) | TWI367112B (https=) |
| WO (1) | WO2008005353A2 (https=) |
| ZA (1) | ZA200900350B (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI343262B (en) * | 2006-09-26 | 2011-06-11 | Schering Corp | Rapidly disintegrating lyophilized oral formulations of a thrombin receptor antagonist |
| EP2120879A2 (en) * | 2006-12-22 | 2009-11-25 | Schering Corporation | Disintegration promoters in solid dose wet granulation formulations |
| US8624050B2 (en) * | 2007-06-22 | 2014-01-07 | General Electric Company | Solution process for transparent conductive oxide coatings |
| WO2009078999A1 (en) | 2007-12-17 | 2009-06-25 | Janssen Pharmaceutica N.V. | Imidazolo-, oxazolo-, and thiazolopyrimidine modulators of trpv1 |
| EP2438060B1 (en) | 2009-06-04 | 2013-10-02 | Merck Sharp & Dohme Corp. | Active metabolite of a thrombin receptor antagonist |
| JP2012529431A (ja) | 2009-06-08 | 2012-11-22 | メルク・シャープ・アンド・ドーム・コーポレーション | トロンビン受容体アンタゴニストおよびクロピドグレルの固定用量錠剤 |
| CN102442965B (zh) * | 2010-09-30 | 2013-12-11 | 天津药物研究院 | 用于治疗血栓性疾病的par-1拮抗剂及其制备方法和用途 |
| WO2017134200A1 (en) | 2016-02-05 | 2017-08-10 | Sanovel Ilac Sanayi Ve Ticaret A.S. | A novel pharmaceutical composition of vorapaxar and metoprolol |
| TR201601548A2 (tr) | 2016-02-05 | 2018-03-21 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Vorapaksar ve metoprololün bi̇r farmasöti̇k kompozi̇syonu |
| MX2020008137A (es) * | 2018-02-02 | 2020-10-19 | Eustralis Pharmaceuticals Ltd Trading As Pressura Neuro | Formulaciones orales y usos de las mismas. |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61137813A (ja) * | 1984-12-07 | 1986-06-25 | Sawai Seiyaku Kk | 持続性セフラジン製剤 |
| JPS63162620A (ja) * | 1986-12-25 | 1988-07-06 | Teisan Seiyaku Kk | 遅溶性顆粒及びそれを用いた持続性複合顆粒 |
| GB9414045D0 (en) * | 1994-07-12 | 1994-08-31 | Berwind Pharma Service | Moisture barrier film coating composition, method, and coated form |
| US20010003588A1 (en) * | 1996-09-12 | 2001-06-14 | Smithkline Beecham Corporation | Controlled release dosage form of [R-(Z)]-alpha-(methoxyimino)-alpha-(1-azabicyclo[2.2.2.]oct-3-yl)acetonitrile monohydrochloride |
| JPH10130142A (ja) * | 1996-10-31 | 1998-05-19 | Zensei Yakuhin Kogyo Kk | 放出持続型圧縮製剤 |
| JPH10298062A (ja) * | 1997-04-24 | 1998-11-10 | Pfizer Pharmaceut Co Ltd | 口腔内速溶型錠剤 |
| CZ298578B6 (cs) * | 1997-11-25 | 2007-11-14 | Schering Corporation | Heterocyklickou skupinou substituovaná tricyklická sloucenina a farmaceutický prostredek ji obsahující |
| US6063847A (en) * | 1997-11-25 | 2000-05-16 | Schering Corporation | Thrombin receptor antagonists |
| WO2001000656A2 (en) | 1999-06-29 | 2001-01-04 | Ortho-Mcneil Pharmaceutical, Inc. | Novel indazole peptidomimetics as thrombin receptor antagonists |
| US6630451B1 (en) | 1999-06-29 | 2003-10-07 | Orthomcneil Pharmaceutical, Inc. | Benzimidazolone peptidometics as thrombin receptor antagonist |
| US6858577B1 (en) | 1999-06-29 | 2005-02-22 | Ortho-Mcneil Pharmaceutical, Inc. | Indole peptidomimetics as thrombin receptor antagonists |
| US7488742B2 (en) | 2000-06-15 | 2009-02-10 | Schering Corporation | Thrombin receptor antagonists |
| AU6690001A (en) * | 2000-06-15 | 2001-12-24 | Schering Corp | Thrombin receptor antagonists |
| US7235567B2 (en) * | 2000-06-15 | 2007-06-26 | Schering Corporation | Crystalline polymorph of a bisulfate salt of a thrombin receptor antagonist |
| US20040192753A1 (en) * | 2000-06-15 | 2004-09-30 | Samuel Chackalamannil | Methods of use of thrombin receptor antagonists |
| WO2002068425A1 (en) * | 2001-02-23 | 2002-09-06 | Ortho-Mcneil Pharmaceutical, Inc. | Aminomethyl-pyrroloquinazoline compounds as thrombin receptor antagonists |
| EP1394152A4 (en) | 2001-04-19 | 2005-02-02 | Eisai Co Ltd | 2-IMINOIMIDAZOLE DERIVATIVES (1) |
| KR100960170B1 (ko) * | 2001-10-18 | 2010-05-26 | 쉐링 코포레이션 | 트롬빈 수용체 길항제로서의 힘바신 동족체 |
| BRPI0309309B8 (pt) * | 2002-04-16 | 2021-05-25 | Merck Sharp & Dohme | antagonistas de receptor de trombina tricíclicos |
| DE10317816A1 (de) * | 2003-04-16 | 2004-11-04 | Claas Selbstfahrende Erntemaschinen Gmbh | Feldhäcksler mit positionierbarer Fahrerkabine |
| CZ300438B6 (cs) * | 2003-11-25 | 2009-05-20 | Pliva Hrvatska D.O.O. | Zpusob prípravy orální pevné lékové formy s okamžitým uvolnováním úcinné látky obsahující jako úcinnou látku polymorfní formu finasteridu |
| JP2009521472A (ja) * | 2005-12-22 | 2009-06-04 | シェーリング コーポレイション | 心肺手術の合併症の予防としてのトロンビンレセプターアンタゴニスト |
| TW200812619A (en) * | 2006-04-06 | 2008-03-16 | Schering Corp | TRA combination therapies |
| US20080026050A1 (en) * | 2006-06-30 | 2008-01-31 | Rajan Gupta | Solid dose formulations of a thrombin receptor antagonist |
| TWI343262B (en) * | 2006-09-26 | 2011-06-11 | Schering Corp | Rapidly disintegrating lyophilized oral formulations of a thrombin receptor antagonist |
| EP2120879A2 (en) * | 2006-12-22 | 2009-11-25 | Schering Corporation | Disintegration promoters in solid dose wet granulation formulations |
| BRPI0809095A2 (pt) * | 2007-03-23 | 2014-09-09 | Schering Corp | Redução de eventos adversos após intervenção percutânea através de uso de um antagonista de receptor de trombina |
-
2007
- 2007-06-28 TW TW096123547A patent/TWI367112B/zh not_active IP Right Cessation
- 2007-06-29 MX MX2009000131A patent/MX2009000131A/es unknown
- 2007-06-29 AR ARP070102934A patent/AR061790A1/es not_active Application Discontinuation
- 2007-06-29 CL CL200701923A patent/CL2007001923A1/es unknown
- 2007-06-29 ES ES07796595.2T patent/ES2616405T3/es active Active
- 2007-06-29 CA CA2656395A patent/CA2656395C/en active Active
- 2007-06-29 WO PCT/US2007/015168 patent/WO2008005353A2/en not_active Ceased
- 2007-06-29 ES ES12159636.5T patent/ES2616354T3/es active Active
- 2007-06-29 US US11/771,520 patent/US20080031943A1/en not_active Abandoned
- 2007-06-29 KR KR1020097000084A patent/KR20090023670A/ko not_active Withdrawn
- 2007-06-29 JP JP2009518301A patent/JP5116764B2/ja not_active Expired - Fee Related
- 2007-06-29 CN CN201510409546.7A patent/CN104922054A/zh active Pending
- 2007-06-29 EP EP12159636.5A patent/EP2491922B1/en active Active
- 2007-06-29 AU AU2007269733A patent/AU2007269733B2/en not_active Ceased
- 2007-06-29 CN CNA2007800325694A patent/CN101511345A/zh active Pending
- 2007-06-29 EP EP07796595.2A patent/EP2034969B1/en active Active
- 2007-06-29 BR BRPI0713935-7A patent/BRPI0713935A2/pt not_active IP Right Cessation
- 2007-07-02 PE PE2007000840A patent/PE20080376A1/es not_active Application Discontinuation
-
2009
- 2009-01-15 ZA ZA200900350A patent/ZA200900350B/xx unknown
- 2009-01-29 NO NO20090467A patent/NO20090467L/no not_active Application Discontinuation
- 2009-01-30 CO CO09008875A patent/CO6150126A2/es unknown
-
2012
- 2012-03-30 JP JP2012082021A patent/JP2012126752A/ja not_active Withdrawn
-
2016
- 2016-03-10 US US15/066,726 patent/US20170224666A9/en not_active Abandoned
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