IT1401284B1 - Nuove formulazioni farmaceutiche idonee per la somministrazione orale di esomeprazolo magnesio diidrato, in forma di compresse mups (multi unit pellets system). - Google Patents

Nuove formulazioni farmaceutiche idonee per la somministrazione orale di esomeprazolo magnesio diidrato, in forma di compresse mups (multi unit pellets system).

Info

Publication number
IT1401284B1
IT1401284B1 ITFI2010A000175A ITFI20100175A IT1401284B1 IT 1401284 B1 IT1401284 B1 IT 1401284B1 IT FI2010A000175 A ITFI2010A000175 A IT FI2010A000175A IT FI20100175 A ITFI20100175 A IT FI20100175A IT 1401284 B1 IT1401284 B1 IT 1401284B1
Authority
IT
Italy
Prior art keywords
dihydrate
oral administration
pharmaceutical formulations
formulations suitable
new pharmaceutical
Prior art date
Application number
ITFI2010A000175A
Other languages
English (en)
Inventor
Tiziano Alighieri
Roberto Valducci
Serozh Avanessian
Original Assignee
Valpharma S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valpharma S P A filed Critical Valpharma S P A
Priority to ITFI2010A000175A priority Critical patent/IT1401284B1/it
Priority to EP11752137.7A priority patent/EP2600847A1/en
Priority to KR1020137005804A priority patent/KR20140021985A/ko
Priority to PCT/EP2011/063524 priority patent/WO2012017074A1/en
Publication of ITFI20100175A1 publication Critical patent/ITFI20100175A1/it
Application granted granted Critical
Publication of IT1401284B1 publication Critical patent/IT1401284B1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ITFI2010A000175A 2010-08-06 2010-08-06 Nuove formulazioni farmaceutiche idonee per la somministrazione orale di esomeprazolo magnesio diidrato, in forma di compresse mups (multi unit pellets system). IT1401284B1 (it)

Priority Applications (4)

Application Number Priority Date Filing Date Title
ITFI2010A000175A IT1401284B1 (it) 2010-08-06 2010-08-06 Nuove formulazioni farmaceutiche idonee per la somministrazione orale di esomeprazolo magnesio diidrato, in forma di compresse mups (multi unit pellets system).
EP11752137.7A EP2600847A1 (en) 2010-08-06 2011-08-05 Oral pharmaceutical formulations of esomeprazole in the form of mups (multi unit pellets system) tablets
KR1020137005804A KR20140021985A (ko) 2010-08-06 2011-08-05 Mups (다중단위 펠릿 시스템) 태블릿 형태의 경구형 에소메프라졸 약학 제형
PCT/EP2011/063524 WO2012017074A1 (en) 2010-08-06 2011-08-05 Oral pharmaceutical formulations of esomeprazole in the form of mups (multi unit pellets system) tablets

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITFI2010A000175A IT1401284B1 (it) 2010-08-06 2010-08-06 Nuove formulazioni farmaceutiche idonee per la somministrazione orale di esomeprazolo magnesio diidrato, in forma di compresse mups (multi unit pellets system).

Publications (2)

Publication Number Publication Date
ITFI20100175A1 ITFI20100175A1 (it) 2012-02-07
IT1401284B1 true IT1401284B1 (it) 2013-07-18

Family

ID=43739462

Family Applications (1)

Application Number Title Priority Date Filing Date
ITFI2010A000175A IT1401284B1 (it) 2010-08-06 2010-08-06 Nuove formulazioni farmaceutiche idonee per la somministrazione orale di esomeprazolo magnesio diidrato, in forma di compresse mups (multi unit pellets system).

Country Status (4)

Country Link
EP (1) EP2600847A1 (it)
KR (1) KR20140021985A (it)
IT (1) IT1401284B1 (it)
WO (1) WO2012017074A1 (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013122553A1 (en) * 2012-02-14 2013-08-22 Mahmut Bilgic A pharmaceutical formulation comprising an atp-ase inhibitor and method for this formulation
WO2013122554A1 (en) 2012-02-14 2013-08-22 Mahmut Bilgic Pellet formulations comprising esomeprazole
EP3288556A4 (en) 2015-04-29 2018-09-19 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10736855B2 (en) 2016-02-25 2020-08-11 Dexcel Pharma Technologies Ltd. Compositions comprising proton pump inhibitors
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
KR20230086439A (ko) 2021-12-08 2023-06-15 주식회사 다산제약 에스오메프라졸 또는 이의 약학적으로 허용가능한 염을 포함하는 약학 제제 및 이의 제조 방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9402431D0 (sv) * 1994-07-08 1994-07-08 Astra Ab New tablet formulation
EP0723436B1 (en) 1994-07-08 2001-09-26 AstraZeneca AB Multiple unit tableted dosage form i
SE0100822D0 (sv) * 2001-03-09 2001-03-09 Astrazeneca Ab Method II to obtain microparticles
WO2005034924A1 (en) 2003-10-14 2005-04-21 Natco Pharma Limited Enteric coated pellets comprising esomeprazole, hard gelatin capsule containing them, and method of preparation
WO2006002077A2 (en) 2004-06-15 2006-01-05 Teva Pharmaceutical Industries Ltd. Stable pharmaceutical formulations of benzimidazole compounds
SI2040684T1 (sl) * 2006-07-11 2013-06-28 Lek Pharmaceuticals D.D. Večenotne tablete
WO2010041276A1 (en) * 2008-10-06 2010-04-15 Jubilant Organosys Limited Pharmaceutical compositions comprising amorphous esomeprazole, dosage forms and process thereof

Also Published As

Publication number Publication date
EP2600847A1 (en) 2013-06-12
ITFI20100175A1 (it) 2012-02-07
KR20140021985A (ko) 2014-02-21
WO2012017074A1 (en) 2012-02-09

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