JP2009540012A5 - - Google Patents
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- Publication number
- JP2009540012A5 JP2009540012A5 JP2009515619A JP2009515619A JP2009540012A5 JP 2009540012 A5 JP2009540012 A5 JP 2009540012A5 JP 2009515619 A JP2009515619 A JP 2009515619A JP 2009515619 A JP2009515619 A JP 2009515619A JP 2009540012 A5 JP2009540012 A5 JP 2009540012A5
- Authority
- JP
- Japan
- Prior art keywords
- diamine
- pyrimidine
- dimethylamino
- propyl
- ethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81387506P | 2006-06-15 | 2006-06-15 | |
| US60/813,875 | 2006-06-15 | ||
| PCT/US2007/071073 WO2007146977A1 (en) | 2006-06-15 | 2007-06-13 | 2-anilino-4-aminoalkyleneaminopyrimidines |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009540012A JP2009540012A (ja) | 2009-11-19 |
| JP2009540012A5 true JP2009540012A5 (enExample) | 2010-07-29 |
| JP5306190B2 JP5306190B2 (ja) | 2013-10-02 |
Family
ID=38611102
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009515619A Expired - Fee Related JP5306190B2 (ja) | 2006-06-15 | 2007-06-13 | ２−アニリノ−４−アミノアルキレンアミノピリミジン |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20070293525A1 (enExample) |
| EP (1) | EP2032543A1 (enExample) |
| JP (1) | JP5306190B2 (enExample) |
| KR (1) | KR20090023698A (enExample) |
| CN (1) | CN101506176A (enExample) |
| AR (1) | AR062822A1 (enExample) |
| AU (1) | AU2007257701A1 (enExample) |
| CA (1) | CA2655315A1 (enExample) |
| CL (1) | CL2007001748A1 (enExample) |
| IL (1) | IL195865A0 (enExample) |
| MX (1) | MX2008016007A (enExample) |
| RU (1) | RU2008152193A (enExample) |
| TW (1) | TW200815368A (enExample) |
| WO (1) | WO2007146977A1 (enExample) |
| ZA (1) | ZA200809945B (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2007257650A1 (en) * | 2006-06-15 | 2007-12-21 | Boehringer Ingelheim International Gmbh | 2-anilino-4-(heterocyclic)amino-pyrimidines as inhibitors of protein kinase C-alpha |
| LT2252300T (lt) * | 2008-02-22 | 2017-02-10 | Rigel Pharmaceuticals, Inc. | 2,4-pirimidindiaminų panaudojimas aterosklerozės gydymui |
| CN102869775A (zh) | 2009-09-30 | 2013-01-09 | 哈佛大学校长及研究员协会 | 通过调节自噬抑制基因产物调节自噬的方法 |
| WO2011075560A1 (en) * | 2009-12-17 | 2011-06-23 | Merck Sharp & Dohme Corp. | Aminopyrimidines as syk inhibitors |
| HUE029196T2 (en) | 2010-06-04 | 2017-02-28 | Hoffmann La Roche | Aminoprimidine derivatives as LRRK2 modulators |
| SG189043A1 (en) | 2010-11-10 | 2013-05-31 | Hoffmann La Roche | Pyrazole aminopyrimidine derivatives as lrrk2 modulators |
| KR101664106B1 (ko) * | 2014-09-11 | 2016-10-10 | 한국화학연구원 | 폴리믹신 b 화합물을 포함하는 심혈관 질환의 예방 및 치료용 약학적 조성물 |
| US10752699B2 (en) | 2015-06-29 | 2020-08-25 | Regents Of The University Of Minnesota | Anti-APOBEC3 antibodies and methods of making and using |
| KR101876514B1 (ko) * | 2016-11-08 | 2018-07-10 | 한국화학연구원 | 신규한 피리미딘화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 암 및 염증질환의 예방 또는 치료용 약학적 조성물 |
| CN109516959A (zh) * | 2018-12-03 | 2019-03-26 | 陕西师范大学 | 2-芳氨基-4-取代嘧啶类衍生物及其在制备抗肿瘤药物中的应用 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB592928A (en) | 1943-06-11 | 1947-10-03 | Francis Henry Swinden Curd | New pyrimidine compounds |
| US2443305A (en) * | 1948-06-15 | Pyrimidine derivatives | ||
| US2437683A (en) * | 1948-03-16 | Pyrimedine compounds and method of | ||
| DE833651C (de) | 1943-11-02 | 1952-03-10 | Ici Ltd | Verfahren zur Herstellung von neuen Pyrimidinabkoemmlingen |
| GB587550A (en) | 1944-09-25 | 1947-04-29 | Francis Henry Swinden Curd | New pyrimidine compounds |
| US3445467A (en) * | 1964-05-25 | 1969-05-20 | Ciba Geigy Corp | Biphenyl diphenylalkane and diphenylether compounds,amino - substituted on the phenyl rings |
| FR2244520B1 (enExample) | 1973-07-06 | 1977-02-04 | Ugine Kuhlmann | |
| GB9523675D0 (en) | 1995-11-20 | 1996-01-24 | Celltech Therapeutics Ltd | Chemical compounds |
| EP0945442A1 (en) | 1998-03-27 | 1999-09-29 | Janssen Pharmaceutica N.V. | Trisubstituted pyrimidine derivatives |
| NZ506679A (en) | 1998-03-27 | 2002-11-26 | Janssen Pharmaceutica Nv | HIV inhibiting pyrimidine derivatives |
| DE69933680T2 (de) * | 1998-08-29 | 2007-08-23 | Astrazeneca Ab | Pyrimidine verbindungen |
| KR20010108394A (ko) | 1999-03-26 | 2001-12-07 | 다비드 에 질레스 | 신규 화합물 |
| GB0016877D0 (en) | 2000-07-11 | 2000-08-30 | Astrazeneca Ab | Chemical compounds |
| MEP13408A (en) * | 2001-05-29 | 2010-06-10 | Bayer Schering Pharma Ag | Cdk inhibiting pyrimidines, production thereof and their use as medicaments |
| US7115617B2 (en) | 2001-08-22 | 2006-10-03 | Amgen Inc. | Amino-substituted pyrimidinyl derivatives and methods of use |
| US6939874B2 (en) | 2001-08-22 | 2005-09-06 | Amgen Inc. | Substituted pyrimidinyl derivatives and methods of use |
| WO2003026665A1 (en) | 2001-09-26 | 2003-04-03 | Bayer Pharmaceuticals Corporation | 2-phenylamino-4-(5-pyrazolylamino)-pyrimidine derivatives as kinase inhibitors, in particular, src kinase inhibitors |
| EP1453516A2 (de) | 2001-10-17 | 2004-09-08 | Boehringer Ingelheim Pharma GmbH & Co.KG | 5-substituierte 4-amino-2-phenylamino-pyrimdinderivate und ihre verwendung als beta-amyloid modulatoren |
| EP1438053B1 (de) | 2001-10-17 | 2008-09-10 | Boehringer Ingelheim Pharma GmbH & Co.KG | Pyrimidinderivate, arzneimittel enthaltend diese verbindungen, deren verwendung und verfahren zu ihrer herstellung |
| BR0213792A (pt) | 2001-11-01 | 2004-12-07 | Janssen Pharmaceutica Nv | Heteroaril aminas como inibidores de glicogênio sintase cinase 3beta (inibidores de gsk3) |
| SE0104140D0 (sv) * | 2001-12-07 | 2001-12-07 | Astrazeneca Ab | Novel Compounds |
| AR039540A1 (es) | 2002-05-13 | 2005-02-23 | Tibotec Pharm Ltd | Compuestos microbicidas con contenido de pirimidina o triazina |
| EA200500721A1 (ru) * | 2002-11-28 | 2005-12-29 | Шеринг Акциенгезельшафт | Пиримидины, ингибирующие chk, pdk и акт, их получение и применение в качестве лекарственных средств |
| EP1571146A4 (en) * | 2002-12-10 | 2010-09-01 | Ono Pharmaceutical Co | NITROGENIC HETEROCYCLIC COMPOUNDS AND THEIR MEDICAL USE |
| WO2005003103A2 (en) | 2003-06-30 | 2005-01-13 | Astrazeneca Ab | 2, 4, 6-tri-substituted 6-membered heterocycles and their use in the treatment of neurodegenerative diseases |
| JP4886511B2 (ja) | 2003-07-30 | 2012-02-29 | ライジェル ファーマシューティカルズ， インコーポレイテッド | ２，４−ピリミジンジアミン化合物による自己免疫疾患の治療または予防方法 |
| JP4741491B2 (ja) | 2003-08-07 | 2011-08-03 | ライジェル ファーマシューティカルズ， インコーポレイテッド | 抗増殖剤としての２，４−ピリミジンジアミン化合物および使用 |
| AU2005205167A1 (en) | 2004-01-16 | 2005-07-28 | Novartis Ag | 2, 4 - diaminopyrimidines and their use for inducing cardiomyogenesis |
| AU2005322855B2 (en) | 2004-12-30 | 2012-09-20 | Exelixis, Inc. | Pyrimidine derivatives as kinase modulators and method of use |
| DE102005016634A1 (de) | 2005-04-12 | 2006-10-19 | Merck Patent Gmbh | Neuartige Aza-Hetercyclen als Kinase-Inhibitoren |
| AU2007257650A1 (en) * | 2006-06-15 | 2007-12-21 | Boehringer Ingelheim International Gmbh | 2-anilino-4-(heterocyclic)amino-pyrimidines as inhibitors of protein kinase C-alpha |
-
2007
- 2007-06-13 US US11/762,406 patent/US20070293525A1/en not_active Abandoned
- 2007-06-13 JP JP2009515619A patent/JP5306190B2/ja not_active Expired - Fee Related
- 2007-06-13 CN CNA2007800304560A patent/CN101506176A/zh active Pending
- 2007-06-13 CA CA002655315A patent/CA2655315A1/en not_active Abandoned
- 2007-06-13 WO PCT/US2007/071073 patent/WO2007146977A1/en not_active Ceased
- 2007-06-13 MX MX2008016007A patent/MX2008016007A/es not_active Application Discontinuation
- 2007-06-13 KR KR1020097000880A patent/KR20090023698A/ko not_active Withdrawn
- 2007-06-13 RU RU2008152193/04A patent/RU2008152193A/ru not_active Application Discontinuation
- 2007-06-13 EP EP07798479A patent/EP2032543A1/en not_active Withdrawn
- 2007-06-13 AU AU2007257701A patent/AU2007257701A1/en not_active Abandoned
- 2007-06-14 TW TW096121543A patent/TW200815368A/zh unknown
- 2007-06-14 CL CL2007001748A patent/CL2007001748A1/es unknown
- 2007-06-15 AR ARP070102630A patent/AR062822A1/es unknown
-
2008
- 2008-11-24 ZA ZA200809945A patent/ZA200809945B/xx unknown
- 2008-12-11 IL IL195865A patent/IL195865A0/en unknown
-
2009
- 2009-03-26 US US12/411,760 patent/US8158641B2/en active Active
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