JP2009538607A - 患者が免疫療法に対する応答者であるかどうかを同定する方法 - Google Patents
患者が免疫療法に対する応答者であるかどうかを同定する方法 Download PDFInfo
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- JP2009538607A JP2009538607A JP2009512510A JP2009512510A JP2009538607A JP 2009538607 A JP2009538607 A JP 2009538607A JP 2009512510 A JP2009512510 A JP 2009512510A JP 2009512510 A JP2009512510 A JP 2009512510A JP 2009538607 A JP2009538607 A JP 2009538607A
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Animal Behavior & Ethology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0610949A GB0610949D0 (en) | 2006-06-02 | 2006-06-02 | Method |
| GB0700761A GB0700761D0 (en) | 2007-01-15 | 2007-01-15 | Method |
| PCT/EP2007/004915 WO2007140958A2 (en) | 2006-06-02 | 2007-05-31 | Method for identifying whether a patient will be responder or not to immunotherapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009538607A true JP2009538607A (ja) | 2009-11-12 |
| JP2009538607A5 JP2009538607A5 (enExample) | 2010-07-08 |
Family
ID=38801855
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009512510A Pending JP2009538607A (ja) | 2006-06-02 | 2007-05-31 | 患者が免疫療法に対する応答者であるかどうかを同定する方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20100021424A1 (enExample) |
| EP (23) | EP2390353A1 (enExample) |
| JP (1) | JP2009538607A (enExample) |
| KR (1) | KR20090017655A (enExample) |
| AR (1) | AR061136A1 (enExample) |
| AU (1) | AU2007256383B2 (enExample) |
| BR (1) | BRPI0712497A2 (enExample) |
| CA (1) | CA2653949A1 (enExample) |
| CL (1) | CL2007001571A1 (enExample) |
| EA (1) | EA200802242A1 (enExample) |
| ES (1) | ES2539042T3 (enExample) |
| MX (1) | MX2008015372A (enExample) |
| PE (1) | PE20080742A1 (enExample) |
| TW (1) | TW200817680A (enExample) |
| WO (1) | WO2007140958A2 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013514090A (ja) * | 2009-12-16 | 2013-04-25 | 日立化成株式会社 | 攻撃的及び防御的免疫マーカーのexvivo誘導により宿主免疫機能を特徴付けるための方法 |
| JP2015528698A (ja) * | 2012-07-12 | 2015-10-01 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 少なくとも7個の遺伝子のサインを用いて、固形癌を患う患者の生存期間および処置に対する応答性を予測するための方法 |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2227558A1 (en) * | 2007-11-30 | 2010-09-15 | GlaxoSmithKline Biologicals SA | Method for classifying cancer patients as responder or non-responder to immunotherapy |
| GB0816867D0 (en) * | 2008-09-15 | 2008-10-22 | Glaxosmithkline Biolog Sa | Method |
| GB2466025A (en) * | 2008-12-08 | 2010-06-09 | Univ Francois Rabelais De Tour | C3/ITGAM polymorphisms and cancer prognosis |
| GB0917457D0 (en) * | 2009-10-06 | 2009-11-18 | Glaxosmithkline Biolog Sa | Method |
| EP2380991A1 (en) | 2010-04-20 | 2011-10-26 | Universitätsklinikum Hamburg-Eppendorf | Method of determining the metastatic potential of a tumor |
| NZ608459A (en) * | 2010-09-15 | 2015-10-30 | Almac Diagnostics Ltd | Molecular diagnostic test for cancer |
| KR101287600B1 (ko) * | 2011-01-04 | 2013-07-18 | 주식회사 젠큐릭스 | 초기유방암의 예후 예측용 유전자 및 이를 이용한 초기유방암의 예후예측 방법 |
| US9926604B2 (en) | 2011-10-14 | 2018-03-27 | The Regents Of The University Of California | Multiplex PCR-based testing of cutaneous squamous cell carcinoma and pseudoepitheliomatous hyperplasia and methods for distinguishing the same |
| JO3519B1 (ar) | 2013-01-25 | 2020-07-05 | Amgen Inc | تركيبات أجسام مضادة لأجل cdh19 و cd3 |
| WO2015077717A1 (en) | 2013-11-25 | 2015-05-28 | The Broad Institute Inc. | Compositions and methods for diagnosing, evaluating and treating cancer by means of the dna methylation status |
| WO2015085147A1 (en) | 2013-12-05 | 2015-06-11 | The Broad Institute Inc. | Polymorphic gene typing and somatic change detection using sequencing data |
| BR112016014410A2 (pt) | 2013-12-20 | 2018-02-20 | The Broad Institute Inc. | terapia de combinação com vacina de neoantígeno |
| US20170202478A1 (en) * | 2014-07-03 | 2017-07-20 | University Of Virginia Patent Foundation | Systems and methods for identifying and profiling muscle patterns |
| US20170298443A1 (en) * | 2014-09-25 | 2017-10-19 | Moffitt Genetics Corporation | Prognostic tumor biomarkers |
| EP3234193B1 (en) | 2014-12-19 | 2020-07-15 | Massachusetts Institute of Technology | Molecular biomarkers for cancer immunotherapy |
| EP3234130B1 (en) | 2014-12-19 | 2020-11-25 | The Broad Institute, Inc. | Methods for profiling the t-cell- receptor repertoire |
| JP6489900B2 (ja) * | 2015-03-30 | 2019-03-27 | 株式会社ジャパンディスプレイ | 入力装置及び表示装置 |
| BR112017024797A2 (pt) | 2015-05-20 | 2018-08-07 | The Broad Institute Inc. | neoantígenos partilhados |
| JP2018520182A (ja) * | 2015-07-14 | 2018-07-26 | アトッサ ジェネティックス インク. | 乳房障害を処置するための経乳頭方法及び組成物 |
| WO2017040520A1 (en) | 2015-08-31 | 2017-03-09 | Hitachi Chemical Co., Ltd. | Molecular methods for assessing urothelial disease |
| US11549149B2 (en) | 2017-01-24 | 2023-01-10 | The Broad Institute, Inc. | Compositions and methods for detecting a mutant variant of a polynucleotide |
| CN118370809A (zh) | 2017-04-03 | 2024-07-23 | 百欧恩泰美国公司 | 蛋白质抗原及其用途 |
| TW201930340A (zh) | 2017-12-18 | 2019-08-01 | 美商尼恩醫療公司 | 新抗原及其用途 |
| BR112020025764A2 (pt) | 2018-06-19 | 2021-05-11 | Biontech Us Inc. | neoantígenos e usos dos mesmos |
| GB201908565D0 (en) * | 2019-06-14 | 2019-07-31 | Cray Innovation Ab | Method of stratifying subjects into sub-groups for therapeutic treatment |
| CN114540504B (zh) * | 2022-04-27 | 2022-07-08 | 广州万德基因医学科技有限公司 | 用于预测肺鳞癌患者免疫疗效的标志物组及系统 |
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| WO2007042286A1 (en) * | 2005-10-11 | 2007-04-19 | Merck Patent Gmbh | Egfr dependent modulation of chemokine expression and influence on therapy and diagnosis of tumors and side effects thereof |
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-
2007
- 2007-05-31 EP EP11162324A patent/EP2390353A1/en not_active Withdrawn
- 2007-05-31 EP EP11162327A patent/EP2390356A1/en not_active Withdrawn
- 2007-05-31 ES ES10159376.2T patent/ES2539042T3/es active Active
- 2007-05-31 EP EP11163261A patent/EP2390358A1/en not_active Withdrawn
- 2007-05-31 EP EP11163268A patent/EP2392675A1/en not_active Withdrawn
- 2007-05-31 EA EA200802242A patent/EA200802242A1/ru unknown
- 2007-05-31 EP EP11162329A patent/EP2392673A1/en not_active Withdrawn
- 2007-05-31 US US12/303,213 patent/US20100021424A1/en not_active Abandoned
- 2007-05-31 EP EP10159376.2A patent/EP2258874B1/en active Active
- 2007-05-31 EP EP11162320A patent/EP2392671A1/en not_active Withdrawn
- 2007-05-31 MX MX2008015372A patent/MX2008015372A/es not_active Application Discontinuation
- 2007-05-31 EP EP11163271A patent/EP2390361A1/en not_active Withdrawn
- 2007-05-31 EP EP11163252A patent/EP2390357A1/en not_active Withdrawn
- 2007-05-31 AU AU2007256383A patent/AU2007256383B2/en not_active Ceased
- 2007-05-31 EP EP11162325A patent/EP2390354A1/en not_active Withdrawn
- 2007-05-31 CL CL200701571A patent/CL2007001571A1/es unknown
- 2007-05-31 EP EP11163264A patent/EP2390360A1/en not_active Withdrawn
- 2007-05-31 EP EP11162323A patent/EP2392672A1/en not_active Withdrawn
- 2007-05-31 BR BRPI0712497-0A patent/BRPI0712497A2/pt not_active IP Right Cessation
- 2007-05-31 PE PE2007000676A patent/PE20080742A1/es not_active Application Discontinuation
- 2007-05-31 EP EP11163720A patent/EP2390367A1/en not_active Withdrawn
- 2007-05-31 EP EP07725789A patent/EP2032719A2/en not_active Withdrawn
- 2007-05-31 CA CA002653949A patent/CA2653949A1/en not_active Abandoned
- 2007-05-31 EP EP11163713A patent/EP2390363A1/en not_active Withdrawn
- 2007-05-31 WO PCT/EP2007/004915 patent/WO2007140958A2/en not_active Ceased
- 2007-05-31 EP EP11163726A patent/EP2390369A1/en not_active Withdrawn
- 2007-05-31 EP EP11162326A patent/EP2390355A1/en not_active Withdrawn
- 2007-05-31 EP EP11163716A patent/EP2390364A1/en not_active Withdrawn
- 2007-05-31 TW TW096119645A patent/TW200817680A/zh unknown
- 2007-05-31 EP EP11163717A patent/EP2390365A1/en not_active Withdrawn
- 2007-05-31 AR ARP070102352A patent/AR061136A1/es not_active Application Discontinuation
- 2007-05-31 EP EP11163719A patent/EP2390366A1/en not_active Withdrawn
- 2007-05-31 EP EP11163722A patent/EP2390368A1/en not_active Withdrawn
- 2007-05-31 EP EP11163263A patent/EP2390359A1/en not_active Withdrawn
- 2007-05-31 EP EP11163277A patent/EP2390362A1/en not_active Withdrawn
- 2007-05-31 KR KR1020087031950A patent/KR20090017655A/ko not_active Ceased
- 2007-05-31 JP JP2009512510A patent/JP2009538607A/ja active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007042286A1 (en) * | 2005-10-11 | 2007-04-19 | Merck Patent Gmbh | Egfr dependent modulation of chemokine expression and influence on therapy and diagnosis of tumors and side effects thereof |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013514090A (ja) * | 2009-12-16 | 2013-04-25 | 日立化成株式会社 | 攻撃的及び防御的免疫マーカーのexvivo誘導により宿主免疫機能を特徴付けるための方法 |
| JP2015528698A (ja) * | 2012-07-12 | 2015-10-01 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 少なくとも7個の遺伝子のサインを用いて、固形癌を患う患者の生存期間および処置に対する応答性を予測するための方法 |
| JP2019162138A (ja) * | 2012-07-12 | 2019-09-26 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 少なくとも7個の遺伝子のサインを用いて、固形癌を患う患者の生存期間および処置に対する応答性を予測するための方法 |
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