EA200802242A1 - Способ определения того, будет или не будет пациент респондером на иммунотерапию - Google Patents

Способ определения того, будет или не будет пациент респондером на иммунотерапию

Info

Publication number
EA200802242A1
EA200802242A1 EA200802242A EA200802242A EA200802242A1 EA 200802242 A1 EA200802242 A1 EA 200802242A1 EA 200802242 A EA200802242 A EA 200802242A EA 200802242 A EA200802242 A EA 200802242A EA 200802242 A1 EA200802242 A1 EA 200802242A1
Authority
EA
Eurasian Patent Office
Prior art keywords
gene expression
responder
immunotherapy
patient
determining
Prior art date
Application number
EA200802242A
Other languages
English (en)
Russian (ru)
Inventor
Винсент Бричард
Джеймс Скотт Кларк
Тьерри Кош
Сванн Ромен Жан-Томас Голис
Оливье Грузелль
Фредерик Леманн
Жамиля Луахед
Original Assignee
Глаксосмитклайн Байолоджикалс С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0610949A external-priority patent/GB0610949D0/en
Priority claimed from GB0700761A external-priority patent/GB0700761D0/en
Application filed by Глаксосмитклайн Байолоджикалс С.А. filed Critical Глаксосмитклайн Байолоджикалс С.А.
Publication of EA200802242A1 publication Critical patent/EA200802242A1/ru

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Public Health (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
EA200802242A 2006-06-02 2007-05-31 Способ определения того, будет или не будет пациент респондером на иммунотерапию EA200802242A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0610949A GB0610949D0 (en) 2006-06-02 2006-06-02 Method
GB0700761A GB0700761D0 (en) 2007-01-15 2007-01-15 Method
PCT/EP2007/004915 WO2007140958A2 (en) 2006-06-02 2007-05-31 Method for identifying whether a patient will be responder or not to immunotherapy

Publications (1)

Publication Number Publication Date
EA200802242A1 true EA200802242A1 (ru) 2009-08-28

Family

ID=38801855

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200802242A EA200802242A1 (ru) 2006-06-02 2007-05-31 Способ определения того, будет или не будет пациент респондером на иммунотерапию

Country Status (15)

Country Link
US (1) US20100021424A1 (enExample)
EP (23) EP2390363A1 (enExample)
JP (1) JP2009538607A (enExample)
KR (1) KR20090017655A (enExample)
AR (1) AR061136A1 (enExample)
AU (1) AU2007256383B2 (enExample)
BR (1) BRPI0712497A2 (enExample)
CA (1) CA2653949A1 (enExample)
CL (1) CL2007001571A1 (enExample)
EA (1) EA200802242A1 (enExample)
ES (1) ES2539042T3 (enExample)
MX (1) MX2008015372A (enExample)
PE (1) PE20080742A1 (enExample)
TW (1) TW200817680A (enExample)
WO (1) WO2007140958A2 (enExample)

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Also Published As

Publication number Publication date
EP2390358A1 (en) 2011-11-30
EP2390369A1 (en) 2011-11-30
AR061136A1 (es) 2008-08-06
BRPI0712497A2 (pt) 2012-09-18
EP2390359A1 (en) 2011-11-30
EP2390353A1 (en) 2011-11-30
JP2009538607A (ja) 2009-11-12
EP2390360A1 (en) 2011-11-30
EP2390368A1 (en) 2011-11-30
EP2390357A1 (en) 2011-11-30
EP2032719A2 (en) 2009-03-11
EP2390367A1 (en) 2011-11-30
EP2390361A1 (en) 2011-11-30
AU2007256383B2 (en) 2013-06-06
EP2392672A1 (en) 2011-12-07
WO2007140958A9 (en) 2009-11-26
EP2390356A1 (en) 2011-11-30
EP2392673A1 (en) 2011-12-07
TW200817680A (en) 2008-04-16
EP2390363A1 (en) 2011-11-30
WO2007140958A2 (en) 2007-12-13
EP2392675A1 (en) 2011-12-07
ES2539042T3 (es) 2015-06-25
EP2390366A1 (en) 2011-11-30
EP2390362A1 (en) 2011-11-30
EP2390365A1 (en) 2011-11-30
EP2390364A1 (en) 2011-11-30
WO2007140958A3 (en) 2008-07-03
AU2007256383A1 (en) 2007-12-13
EP2390355A1 (en) 2011-11-30
EP2258874A1 (en) 2010-12-08
EP2390354A1 (en) 2011-11-30
CL2007001571A1 (es) 2008-05-16
PE20080742A1 (es) 2008-08-06
MX2008015372A (es) 2009-03-23
US20100021424A1 (en) 2010-01-28
EP2258874B1 (en) 2015-03-18
EP2392671A1 (en) 2011-12-07
CA2653949A1 (en) 2007-12-13
KR20090017655A (ko) 2009-02-18

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