PE20080742A1 - Perfil genico y procedimiento de identificacion - Google Patents
Perfil genico y procedimiento de identificacionInfo
- Publication number
- PE20080742A1 PE20080742A1 PE2007000676A PE2007000676A PE20080742A1 PE 20080742 A1 PE20080742 A1 PE 20080742A1 PE 2007000676 A PE2007000676 A PE 2007000676A PE 2007000676 A PE2007000676 A PE 2007000676A PE 20080742 A1 PE20080742 A1 PE 20080742A1
- Authority
- PE
- Peru
- Prior art keywords
- immunotherapy
- gene profile
- cancer
- identification procedure
- gene
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Animal Behavior & Ethology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
REFERIDA A UN PERFIL GENICO INDICATIVO DE UN PROBABILIDAD AUMENTADA DE UNA RESPUESTA A UNA INMUNOTERAPIA QUE COMPRENDE LA REGULACION DIFERENCIAL DE AL MENOS UN GEN DE ACTIVACION INMUNE, DONDE LA INMUNOTERAPIA ES UNA INMUNOTERAPIA DE CANCER ESPECIFICA DEL ANTIGENO MAGE QUE SON ANTIGENOS CODIFICADOS POR LA FAMILIA DE GENES DE ANTIGENO ASOCIADOS A MELANOMA. TAMBIEN ESTA REFERIDA A UN PROCEDIMIENTO DE IDENTIFICACION DE DICHO PERFIL GENICO Y A UN KIT. EL PERFIL GENICO DE UN PACIENTE, EL PROCEDIMIENTO DE IDENTIFICACION DEL PERFIL GENICO Y EL KIT SON UTILES EN LA IDENTIFICACION DE PACIENTES CON CANCER QUE ES PROBABLE QUE RESPONDAN A LA INMUNOTERAPIA APROPIADA
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0610949A GB0610949D0 (en) | 2006-06-02 | 2006-06-02 | Method |
GB0700761A GB0700761D0 (en) | 2007-01-15 | 2007-01-15 | Method |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20080742A1 true PE20080742A1 (es) | 2008-08-06 |
Family
ID=38801855
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2007000676A PE20080742A1 (es) | 2006-06-02 | 2007-05-31 | Perfil genico y procedimiento de identificacion |
Country Status (15)
Country | Link |
---|---|
US (1) | US20100021424A1 (es) |
EP (23) | EP2390362A1 (es) |
JP (1) | JP2009538607A (es) |
KR (1) | KR20090017655A (es) |
AR (1) | AR061136A1 (es) |
AU (1) | AU2007256383B2 (es) |
BR (1) | BRPI0712497A2 (es) |
CA (1) | CA2653949A1 (es) |
CL (1) | CL2007001571A1 (es) |
EA (1) | EA200802242A1 (es) |
ES (1) | ES2539042T3 (es) |
MX (1) | MX2008015372A (es) |
PE (1) | PE20080742A1 (es) |
TW (1) | TW200817680A (es) |
WO (1) | WO2007140958A2 (es) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2227558A1 (en) * | 2007-11-30 | 2010-09-15 | GlaxoSmithKline Biologicals SA | Method for classifying cancer patients as responder or non-responder to immunotherapy |
GB0816867D0 (en) * | 2008-09-15 | 2008-10-22 | Glaxosmithkline Biolog Sa | Method |
GB2466025A (en) * | 2008-12-08 | 2010-06-09 | Univ Francois Rabelais De Tour | C3/ITGAM polymorphisms and cancer prognosis |
GB0917457D0 (en) * | 2009-10-06 | 2009-11-18 | Glaxosmithkline Biolog Sa | Method |
WO2011084333A1 (en) * | 2009-12-16 | 2011-07-14 | Hitachi Chemical Co., Ltd. | Method for characterizing host immune function by ex vivo induction of offensive and defensive immune markers |
EP2380991A1 (en) | 2010-04-20 | 2011-10-26 | Universitätsklinikum Hamburg-Eppendorf | Method of determining the metastatic potential of a tumor |
SG188397A1 (en) * | 2010-09-15 | 2013-04-30 | Almac Diagnostics Ltd | Molecular diagnostic test for cancer |
KR101287600B1 (ko) * | 2011-01-04 | 2013-07-18 | 주식회사 젠큐릭스 | 초기유방암의 예후 예측용 유전자 및 이를 이용한 초기유방암의 예후예측 방법 |
CN103987861A (zh) | 2011-10-14 | 2014-08-13 | 加州大学评议会 | 皮肤鳞状细胞癌和假性上皮瘤样增生的基于多重pcr的测试及其区分方法 |
EP2872646B1 (en) * | 2012-07-12 | 2017-08-30 | Institut National de la Sante et de la Recherche Medicale (INSERM) | Methods for predicting the survival time and treatment responsiveness of a patient suffering from a solid cancer with a signature of at least 7 genes |
JO3519B1 (ar) | 2013-01-25 | 2020-07-05 | Amgen Inc | تركيبات أجسام مضادة لأجل cdh19 و cd3 |
WO2015077717A1 (en) | 2013-11-25 | 2015-05-28 | The Broad Institute Inc. | Compositions and methods for diagnosing, evaluating and treating cancer by means of the dna methylation status |
WO2015085147A1 (en) | 2013-12-05 | 2015-06-11 | The Broad Institute Inc. | Polymorphic gene typing and somatic change detection using sequencing data |
KR20230076867A (ko) | 2013-12-20 | 2023-05-31 | 더 브로드 인스티튜트, 인코퍼레이티드 | 신생항원 백신과의 병용 요법 |
CA2953703A1 (en) * | 2014-07-03 | 2016-01-07 | University Of Virginia Patent Foundation | Systems and methods for identifying and profiling muscle patterns |
WO2016049276A1 (en) * | 2014-09-25 | 2016-03-31 | Moffitt Genetics Corporation | Prognostic tumor biomarkers |
US10975442B2 (en) | 2014-12-19 | 2021-04-13 | Massachusetts Institute Of Technology | Molecular biomarkers for cancer immunotherapy |
WO2016100977A1 (en) | 2014-12-19 | 2016-06-23 | The Broad Institute Inc. | Methods for profiling the t-cel- receptor repertoire |
JP6489900B2 (ja) * | 2015-03-30 | 2019-03-27 | 株式会社ジャパンディスプレイ | 入力装置及び表示装置 |
MX2017014700A (es) | 2015-05-20 | 2018-08-15 | Broad Inst Inc | Neoantigenos compartidos. |
CA2992282A1 (en) * | 2015-07-14 | 2017-01-19 | Atossa Genetics Inc. | Transpapillary methods and compositions for treating breast disorders |
DE112016003948T5 (de) | 2015-08-31 | 2018-05-09 | City Of Sapporo | Molekulare verfahren zum beurteilen einer urothelialen erkrankung |
WO2018140391A1 (en) | 2017-01-24 | 2018-08-02 | The Broad Institute, Inc. | Compositions and methods for detecting a mutant variant of a polynucleotide |
US11793867B2 (en) | 2017-12-18 | 2023-10-24 | Biontech Us Inc. | Neoantigens and uses thereof |
GB201908565D0 (en) * | 2019-06-14 | 2019-07-31 | Cray Innovation Ab | Method of stratifying subjects into sub-groups for therapeutic treatment |
CN114540504B (zh) * | 2022-04-27 | 2022-07-08 | 广州万德基因医学科技有限公司 | 用于预测肺鳞癌患者免疫疗效的标志物组及系统 |
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-
2007
- 2007-05-31 AR ARP070102352A patent/AR061136A1/es not_active Application Discontinuation
- 2007-05-31 US US12/303,213 patent/US20100021424A1/en not_active Abandoned
- 2007-05-31 EP EP11163277A patent/EP2390362A1/en not_active Withdrawn
- 2007-05-31 EP EP11162326A patent/EP2390355A1/en not_active Withdrawn
- 2007-05-31 EP EP11163713A patent/EP2390363A1/en not_active Withdrawn
- 2007-05-31 JP JP2009512510A patent/JP2009538607A/ja active Pending
- 2007-05-31 EP EP11163716A patent/EP2390364A1/en not_active Withdrawn
- 2007-05-31 MX MX2008015372A patent/MX2008015372A/es not_active Application Discontinuation
- 2007-05-31 EP EP11162320A patent/EP2392671A1/en not_active Withdrawn
- 2007-05-31 EP EP11162324A patent/EP2390353A1/en not_active Withdrawn
- 2007-05-31 EP EP11162327A patent/EP2390356A1/en not_active Withdrawn
- 2007-05-31 PE PE2007000676A patent/PE20080742A1/es not_active Application Discontinuation
- 2007-05-31 CA CA002653949A patent/CA2653949A1/en not_active Abandoned
- 2007-05-31 EP EP11162323A patent/EP2392672A1/en not_active Withdrawn
- 2007-05-31 BR BRPI0712497-0A patent/BRPI0712497A2/pt not_active IP Right Cessation
- 2007-05-31 ES ES10159376.2T patent/ES2539042T3/es active Active
- 2007-05-31 EP EP11162329A patent/EP2392673A1/en not_active Withdrawn
- 2007-05-31 EA EA200802242A patent/EA200802242A1/ru unknown
- 2007-05-31 KR KR1020087031950A patent/KR20090017655A/ko not_active Application Discontinuation
- 2007-05-31 EP EP11163726A patent/EP2390369A1/en not_active Withdrawn
- 2007-05-31 CL CL200701571A patent/CL2007001571A1/es unknown
- 2007-05-31 EP EP11163271A patent/EP2390361A1/en not_active Withdrawn
- 2007-05-31 AU AU2007256383A patent/AU2007256383B2/en not_active Ceased
- 2007-05-31 TW TW096119645A patent/TW200817680A/zh unknown
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- 2007-05-31 EP EP07725789A patent/EP2032719A2/en not_active Withdrawn
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- 2007-05-31 EP EP10159376.2A patent/EP2258874B1/en active Active
- 2007-05-31 EP EP11162325A patent/EP2390354A1/en not_active Withdrawn
- 2007-05-31 EP EP11163264A patent/EP2390360A1/en not_active Withdrawn
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