AR054536A1 - Terapia de combinacion de anticuerpo anti- ctla -4 y oligodesoxinucleotido sintetico que contiene motivo cgp para el tratamiento del cancer - Google Patents

Terapia de combinacion de anticuerpo anti- ctla -4 y oligodesoxinucleotido sintetico que contiene motivo cgp para el tratamiento del cancer

Info

Publication number
AR054536A1
AR054536A1 ARP060102913A ARP060102913A AR054536A1 AR 054536 A1 AR054536 A1 AR 054536A1 AR P060102913 A ARP060102913 A AR P060102913A AR P060102913 A ARP060102913 A AR P060102913A AR 054536 A1 AR054536 A1 AR 054536A1
Authority
AR
Argentina
Prior art keywords
ctla
oligodesoxinucleotido
synthetic
reason
combination therapy
Prior art date
Application number
ARP060102913A
Other languages
English (en)
Original Assignee
Pfizer
Coley Pharm Group Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer, Coley Pharm Group Inc filed Critical Pfizer
Publication of AR054536A1 publication Critical patent/AR054536A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Administracion de un anticuerpo anti-CTLA-4, particularmente anticuerpos humanos contra CTLA-4 humano, tales como aquellos que tienen secuencias de aminoácidos de anticuerpos 3.1.1, 4.1.1, 4.8.1, 4.10.2, 4.13.1, 4.14.3, 6.1.1, 11.2.1, 11.6.1, 11.7.1, 12.3.1.1, 12.9.1.1, y MDX-010, en combinacion con un nucleotido inmunoestimulador, es decir CpG ODN PF3512676 para el tratamiento del cáncer. La administracion de una combinacion de un anticuerpo anti-CTLA-4 y CpG ODN PF3512676 como terapia neoadyuvante, adyuvante, de primera línea, segunda línea y tercera línea para el cáncer, ya sea localizado o metastásico, y en cualquier punto a lo largo de la escala continua de la enfermedad (por ej., en cualquier etapa del cáncer).
ARP060102913A 2005-07-07 2006-07-06 Terapia de combinacion de anticuerpo anti- ctla -4 y oligodesoxinucleotido sintetico que contiene motivo cgp para el tratamiento del cancer AR054536A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69708205P 2005-07-07 2005-07-07

Publications (1)

Publication Number Publication Date
AR054536A1 true AR054536A1 (es) 2007-06-27

Family

ID=37492285

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060102913A AR054536A1 (es) 2005-07-07 2006-07-06 Terapia de combinacion de anticuerpo anti- ctla -4 y oligodesoxinucleotido sintetico que contiene motivo cgp para el tratamiento del cancer

Country Status (17)

Country Link
US (2) US20090117132A1 (es)
EP (1) EP1904530A2 (es)
JP (1) JP2009500412A (es)
KR (1) KR20080030656A (es)
CN (1) CN101268101A (es)
AR (1) AR054536A1 (es)
AU (1) AU2006269555A1 (es)
BR (1) BRPI0612408A2 (es)
CA (1) CA2614320A1 (es)
EA (1) EA200800268A1 (es)
IL (1) IL188588A0 (es)
MX (1) MX2008000379A (es)
NZ (1) NZ565311A (es)
SG (1) SG163583A1 (es)
TW (1) TW200801042A (es)
WO (1) WO2007008463A2 (es)
ZA (1) ZA200801190B (es)

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CA2614320A1 (en) 2007-01-18
US20090117132A1 (en) 2009-05-07
AU2006269555A1 (en) 2007-01-18
NZ565311A (en) 2009-10-30
ZA200801190B (en) 2008-12-31
WO2007008463A3 (en) 2007-05-24
WO2007008463A2 (en) 2007-01-18
IL188588A0 (en) 2008-04-13
US20120003179A1 (en) 2012-01-05
KR20080030656A (ko) 2008-04-04
JP2009500412A (ja) 2009-01-08
BRPI0612408A2 (pt) 2010-11-03
EP1904530A2 (en) 2008-04-02
MX2008000379A (es) 2008-03-18
TW200801042A (en) 2008-01-01
CN101268101A (zh) 2008-09-17
SG163583A1 (en) 2010-08-30
EA200800268A1 (ru) 2008-06-30

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