ATE476196T1 - Zusammensetzung zur auslösung, verbesserung und erhaltung von immunantworten gegen mhc-klasse-i- beschränkte epitope, für prophylaktische oder therapeutische zwecke - Google Patents
Zusammensetzung zur auslösung, verbesserung und erhaltung von immunantworten gegen mhc-klasse-i- beschränkte epitope, für prophylaktische oder therapeutische zweckeInfo
- Publication number
- ATE476196T1 ATE476196T1 AT04776760T AT04776760T ATE476196T1 AT E476196 T1 ATE476196 T1 AT E476196T1 AT 04776760 T AT04776760 T AT 04776760T AT 04776760 T AT04776760 T AT 04776760T AT E476196 T1 ATE476196 T1 AT E476196T1
- Authority
- AT
- Austria
- Prior art keywords
- prophylactic
- mhc class
- immune responses
- therapeutic purposes
- initiating
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 230000000069 prophylactic effect Effects 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 230000000977 initiatory effect Effects 0.000 title 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5156—Animal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47939303P | 2003-06-17 | 2003-06-17 | |
| PCT/US2004/019546 WO2005002621A2 (en) | 2003-06-17 | 2004-06-17 | Methods to elicit, enhance and sustain immune responses against mhc class i-restricted epitopes, for prophylactic or therapeutic purposes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE476196T1 true ATE476196T1 (de) | 2010-08-15 |
Family
ID=33563795
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04776760T ATE476196T1 (de) | 2003-06-17 | 2004-06-17 | Zusammensetzung zur auslösung, verbesserung und erhaltung von immunantworten gegen mhc-klasse-i- beschränkte epitope, für prophylaktische oder therapeutische zwecke |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20050079152A1 (de) |
| EP (3) | EP2246067B1 (de) |
| JP (2) | JP5127224B2 (de) |
| AT (1) | ATE476196T1 (de) |
| AU (1) | AU2004253479B9 (de) |
| CA (1) | CA2529057A1 (de) |
| DE (1) | DE602004028468D1 (de) |
| DK (1) | DK1635863T3 (de) |
| ES (1) | ES2350043T3 (de) |
| MX (1) | MXPA05013973A (de) |
| PL (1) | PL1635863T3 (de) |
| WO (1) | WO2005002621A2 (de) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6727230B1 (en) * | 1994-03-25 | 2004-04-27 | Coley Pharmaceutical Group, Inc. | Immune stimulation by phosphorothioate oligonucleotide analogs |
| US20030026782A1 (en) * | 1995-02-07 | 2003-02-06 | Arthur M. Krieg | Immunomodulatory oligonucleotides |
| US6207646B1 (en) * | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US6977074B2 (en) | 1997-07-10 | 2005-12-20 | Mannkind Corporation | Method of inducing a CTL response |
| US6693086B1 (en) * | 1998-06-25 | 2004-02-17 | National Jewish Medical And Research Center | Systemic immune activation method using nucleic acid-lipid complexes |
| US20030022854A1 (en) | 1998-06-25 | 2003-01-30 | Dow Steven W. | Vaccines using nucleic acid-lipid complexes |
| EP2204186B1 (de) | 1999-02-17 | 2016-04-06 | CSL Limited | Immunogene Komplexe und damit zusammenhängende Verfahren |
| WO2001037869A1 (en) * | 1999-11-19 | 2001-05-31 | Csl Limited | Vaccine compositions |
| US20040131628A1 (en) * | 2000-03-08 | 2004-07-08 | Bratzler Robert L. | Nucleic acids for the treatment of disorders associated with microorganisms |
| KR100917101B1 (ko) * | 2000-08-04 | 2009-09-15 | 도요 보세키 가부시키가이샤 | 플렉시블 금속적층체 및 그 제조방법 |
| US7807803B2 (en) | 2002-07-03 | 2010-10-05 | Coley Pharmaceutical Group, Inc. | Nucleic acid compositions for stimulating immune responses |
| US20040053880A1 (en) * | 2002-07-03 | 2004-03-18 | Coley Pharmaceutical Group, Inc. | Nucleic acid compositions for stimulating immune responses |
| US7576066B2 (en) * | 2002-07-03 | 2009-08-18 | Coley Pharmaceutical Group, Inc. | Nucleic acid compositions for stimulating immune responses |
| US7569553B2 (en) * | 2002-07-03 | 2009-08-04 | Coley Pharmaceutical Group, Inc. | Nucleic acid compositions for stimulating immune responses |
| US7605138B2 (en) * | 2002-07-03 | 2009-10-20 | Coley Pharmaceutical Group, Inc. | Nucleic acid compositions for stimulating immune responses |
| ZA200503511B (en) * | 2002-10-29 | 2006-10-25 | Coley Pharmaceutical Group Ltd | Use of CPG oligonucleotides in the treatment of hepatitis C virus infection |
| AU2004226605A1 (en) * | 2003-04-02 | 2004-10-14 | Coley Pharmaceutical Group, Ltd. | Immunostimulatory nucleic acid oil-in-water formulations for topical application |
| US7178491B2 (en) * | 2003-06-05 | 2007-02-20 | Caterpillar Inc | Control system and method for engine valve actuator |
| US20060159689A1 (en) * | 2004-06-17 | 2006-07-20 | Chih-Sheng Chiang | Combinations of tumor-associated antigens in diagnostics for various types of cancers |
| US20060008468A1 (en) * | 2004-06-17 | 2006-01-12 | Chih-Sheng Chiang | Combinations of tumor-associated antigens in diagnostics for various types of cancers |
| AU2005265182B2 (en) * | 2004-06-17 | 2012-06-21 | Mannkind Corporation | Epitope analogs |
| CA2570998A1 (en) * | 2004-06-17 | 2006-01-26 | Mannkind Corporation | Improved efficacy of active immunotherapy by integrating diagnostic with therapeutic methods |
| WO2007001448A2 (en) | 2004-11-04 | 2007-01-04 | Massachusetts Institute Of Technology | Coated controlled release polymer particles as efficient oral delivery vehicles for biopharmaceuticals |
| MX2007008010A (es) * | 2004-12-29 | 2007-09-07 | Mannkind Corp | Metodos para desviar celulas cd4+ en la induccion de una inmuno respuesta. |
| US20060153844A1 (en) * | 2004-12-29 | 2006-07-13 | Thomas Kundig | Methods to trigger, maintain and manipulate immune responses by targeted administration of biological response modifiers into lymphoid organs |
| AU2005321898B2 (en) * | 2004-12-29 | 2012-07-19 | Mannkind Corporation | Use of compositions comprising various tumor-associated antigens as anti-cancer vaccines |
| WO2006071989A2 (en) * | 2004-12-29 | 2006-07-06 | Mannkind Corporation | Methods to elicit, enhance and sustain immune responses against mhc class i-restricted epitopes, for prophylactic or therapeutic purposes |
| SG162817A1 (en) | 2005-06-17 | 2010-07-29 | Mannkind Corp | Methods and compositions.to elicit multivalent immune responses against dominant and subdominant epitopes, expressed on cancer cells and tumor stroma |
| JP2008543314A (ja) * | 2005-06-17 | 2008-12-04 | マンカインド コーポレイション | エピトープ類似体 |
| WO2006138568A2 (en) * | 2005-06-17 | 2006-12-28 | Mannkind Corporation | Multivalent entrain-and-amplify immunotherapeutics for carcinoma |
| US20090117132A1 (en) * | 2005-07-07 | 2009-05-07 | Pfizer, Inc. | Anti-Ctla-4 Antibody and Cpg-Motif-Containing Synthetic Oligodeoxynucleotide Combination Therapy for Cancer Treatment |
| WO2007065633A1 (en) * | 2005-12-05 | 2007-06-14 | Imvision Ag | Modulation of the immune response by administration of intralymphatic transduction allergen (itag) -molecules |
| EP1792627A1 (de) * | 2005-12-05 | 2007-06-06 | ImVisioN AG | Eine Intralymphatische Transduktion Allergen (ITAG) enthaltende Zusammensetzung zur Verwendung in der Modulation des Immunsystems |
| WO2007070682A2 (en) | 2005-12-15 | 2007-06-21 | Massachusetts Institute Of Technology | System for screening particles |
| WO2007085266A1 (en) * | 2006-01-30 | 2007-08-02 | Dako Denmark A/S | High-speed quantification of antigen specific t-cells in whole blood by flow cytometry |
| ES2776100T3 (es) | 2006-03-31 | 2020-07-29 | Massachusetts Inst Technology | Sistema para el suministro dirigido de agentes terapéuticos |
| WO2007133807A2 (en) | 2006-05-15 | 2007-11-22 | Massachusetts Institute Of Technology | Polymers for functional particles |
| PT2032163E (pt) | 2006-06-15 | 2013-04-11 | Novartis Ag | Regime em multidoses de vacinação de influenza poupador de adjuvante |
| US9381477B2 (en) * | 2006-06-23 | 2016-07-05 | Massachusetts Institute Of Technology | Microfluidic synthesis of organic nanoparticles |
| WO2008008541A2 (en) * | 2006-07-14 | 2008-01-17 | Mannkind Corporation | Methods to elicit, enhance and sustain immune responses against mhc class-i restricted epitopes, for prophylactic or therapeutic purposes |
| US20100144845A1 (en) * | 2006-08-04 | 2010-06-10 | Massachusetts Institute Of Technology | Oligonucleotide systems for targeted intracellular delivery |
| US9217129B2 (en) | 2007-02-09 | 2015-12-22 | Massachusetts Institute Of Technology | Oscillating cell culture bioreactor |
| JP5755839B2 (ja) * | 2007-02-15 | 2015-07-29 | マンカインド コーポレイション | Ｔ細胞応答の増強方法 |
| EP2361930A3 (de) | 2007-03-26 | 2011-10-26 | Dako Denmark A/S | Multimere von peptide-mhc komplexen und deren verwendung in borrelia infektionskrankheiten |
| EP3533461A3 (de) * | 2007-03-26 | 2019-12-18 | Academisch Ziekenhuis Leiden h.o.d.n. LUMC | Von prame abstammende peptide und immunogene zusammensetzungen damit |
| JP2010523595A (ja) * | 2007-04-04 | 2010-07-15 | マサチューセッツ インスティテュート オブ テクノロジー | ポリ（アミノ酸）ターゲッティング部分 |
| EP3023436A1 (de) * | 2007-07-03 | 2016-05-25 | Dako Denmark A/S | Verbesserte verfahren zur herstellung, markierung und verwendung von mhc-multimeren |
| WO2009039854A2 (en) | 2007-09-27 | 2009-04-02 | Dako Denmark A/S | Mhc multimers in tuberculosis diagnostics, vaccine and therapeutics |
| US10736848B2 (en) | 2007-10-12 | 2020-08-11 | Massachusetts Institute Of Technology | Vaccine nanotechnology |
| US10968269B1 (en) | 2008-02-28 | 2021-04-06 | Agilent Technologies, Inc. | MHC multimers in borrelia diagnostics and disease |
| US10722562B2 (en) | 2008-07-23 | 2020-07-28 | Immudex Aps | Combinatorial analysis and repair |
| GB0817244D0 (en) * | 2008-09-20 | 2008-10-29 | Univ Cardiff | Use of a protein kinase inhibitor to detect immune cells, such as T cells |
| US10369204B2 (en) | 2008-10-02 | 2019-08-06 | Dako Denmark A/S | Molecular vaccines for infectious disease |
| US8343497B2 (en) | 2008-10-12 | 2013-01-01 | The Brigham And Women's Hospital, Inc. | Targeting of antigen presenting cells with immunonanotherapeutics |
| US8591905B2 (en) | 2008-10-12 | 2013-11-26 | The Brigham And Women's Hospital, Inc. | Nicotine immunonanotherapeutics |
| US8343498B2 (en) | 2008-10-12 | 2013-01-01 | Massachusetts Institute Of Technology | Adjuvant incorporation in immunonanotherapeutics |
| US8277812B2 (en) | 2008-10-12 | 2012-10-02 | Massachusetts Institute Of Technology | Immunonanotherapeutics that provide IgG humoral response without T-cell antigen |
| WO2011050344A2 (en) | 2009-10-23 | 2011-04-28 | Mannkind Corporation | Cancer immunotherapy and method of treatment |
| US9994443B2 (en) | 2010-11-05 | 2018-06-12 | Selecta Biosciences, Inc. | Modified nicotinic compounds and related methods |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2606601A (en) | 1948-12-14 | 1952-08-12 | Knoll Associates | Chair having a back rest in the form of a shell-like body |
| WO1998058956A2 (en) * | 1997-06-23 | 1998-12-30 | Ludwig Institute For Cancer Research | Methods for inducing an immune response involving prime-boost protocols |
| EP2286831A1 (de) | 1997-07-10 | 2011-02-23 | Mannkind Corporation | Methode zur Induktion von zytotoxischen T-cell Antworten |
| US6977074B2 (en) * | 1997-07-10 | 2005-12-20 | Mannkind Corporation | Method of inducing a CTL response |
| US6709844B1 (en) | 2000-11-16 | 2004-03-23 | Mannkind Corporation | Avoidance of undesirable replication intermediates in plasmid propagation |
| US20030138808A1 (en) | 1998-02-19 | 2003-07-24 | Simard John J.L. | Expression vectors encoding epitopes of target-associated antigens |
| CA2721011A1 (en) * | 1999-10-22 | 2001-05-03 | Aventis Pasteur Limited | Modified gp100 and uses thereof |
| US6861234B1 (en) * | 2000-04-28 | 2005-03-01 | Mannkind Corporation | Method of epitope discovery |
| US20030215425A1 (en) | 2001-12-07 | 2003-11-20 | Simard John J. L. | Epitope synchronization in antigen presenting cells |
| US6773695B2 (en) * | 2000-10-05 | 2004-08-10 | Mannkind Corporation | Modulation of allergic response |
| EP1372736A4 (de) | 2001-03-07 | 2004-11-17 | Mannkind Corp | Präparate gegen gefässneubildung bei krebs |
| WO2002080648A2 (en) * | 2001-04-05 | 2002-10-17 | Chiron Corporation | Mucosal boosting following parenteral priming |
| WO2003008537A2 (en) | 2001-04-06 | 2003-01-30 | Mannkind Corporation | Epitope sequences |
| US7076244B2 (en) | 2001-07-23 | 2006-07-11 | Research In Motion Limited | System and method for pushing information to a mobile device |
| GB0118532D0 (en) * | 2001-07-30 | 2001-09-19 | Isis Innovation | Materials and methods relating to improved vaccination strategies |
| EP2314712B1 (de) | 2001-11-07 | 2014-01-08 | Mannkind Corporation | Für Epitope von Antigenen kodierende Expressionsvektoren sowie Verfahren zu deren Konzeption |
| CA2467486A1 (en) * | 2001-11-30 | 2003-06-12 | Isis Innovation Limited | Vaccine |
| CN1691964A (zh) | 2002-09-06 | 2005-11-02 | 曼康公司 | 表位序列 |
| WO2004110485A1 (en) * | 2003-06-13 | 2004-12-23 | Palmowski Michael J | Materials and methods for improved vaccination |
| US9469902B2 (en) | 2014-02-18 | 2016-10-18 | Lam Research Corporation | Electroless deposition of continuous platinum layer |
| US9814289B2 (en) | 2015-04-08 | 2017-11-14 | Otter Products, Llc | Protective folio case for an electronic device |
| EP3636238B1 (de) | 2018-10-12 | 2021-04-28 | Liko Research & Development AB | Tore mit übergangsrampen für deckenhubschienen |
-
2004
- 2004-06-17 DE DE602004028468T patent/DE602004028468D1/de active Active
- 2004-06-17 JP JP2006517407A patent/JP5127224B2/ja not_active Expired - Fee Related
- 2004-06-17 EP EP10171754.4A patent/EP2246067B1/de not_active Not-in-force
- 2004-06-17 ES ES04776760T patent/ES2350043T3/es active Active
- 2004-06-17 MX MXPA05013973A patent/MXPA05013973A/es active IP Right Grant
- 2004-06-17 AU AU2004253479A patent/AU2004253479B9/en not_active Ceased
- 2004-06-17 EP EP10180566A patent/EP2356999A1/de not_active Ceased
- 2004-06-17 AT AT04776760T patent/ATE476196T1/de active
- 2004-06-17 PL PL04776760T patent/PL1635863T3/pl unknown
- 2004-06-17 EP EP04776760A patent/EP1635863B1/de not_active Not-in-force
- 2004-06-17 US US10/871,707 patent/US20050079152A1/en not_active Abandoned
- 2004-06-17 WO PCT/US2004/019546 patent/WO2005002621A2/en active Application Filing
- 2004-06-17 DK DK04776760.3T patent/DK1635863T3/da active
- 2004-06-17 CA CA002529057A patent/CA2529057A1/en not_active Abandoned
-
2012
- 2012-09-10 JP JP2012198859A patent/JP2013028619A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DK1635863T3 (da) | 2010-11-22 |
| WO2005002621A3 (en) | 2005-08-04 |
| PL1635863T3 (pl) | 2011-01-31 |
| EP2246067B1 (de) | 2017-02-15 |
| JP5127224B2 (ja) | 2013-01-23 |
| MXPA05013973A (es) | 2006-03-02 |
| EP1635863B1 (de) | 2010-08-04 |
| JP2013028619A (ja) | 2013-02-07 |
| AU2004253479B2 (en) | 2011-09-01 |
| ES2350043T3 (es) | 2011-01-17 |
| EP1635863A2 (de) | 2006-03-22 |
| AU2004253479A1 (en) | 2005-01-13 |
| AU2004253479B9 (en) | 2011-10-06 |
| WO2005002621A2 (en) | 2005-01-13 |
| EP2246067A2 (de) | 2010-11-03 |
| US20050079152A1 (en) | 2005-04-14 |
| CA2529057A1 (en) | 2005-01-13 |
| EP2246067A3 (de) | 2011-07-13 |
| EP2356999A1 (de) | 2011-08-17 |
| JP2007523863A (ja) | 2007-08-23 |
| DE602004028468D1 (de) | 2010-09-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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