CL2007001571A1 - Perfil genico indicativo de probabilidad aumentada de que un paciente responda o no a una inmunoterapia; uso de dicho perfil; procedimiento de identificacion del perfil; uso de sonda para identificar la expresion diferencial de al menos un gen de act - Google Patents
Perfil genico indicativo de probabilidad aumentada de que un paciente responda o no a una inmunoterapia; uso de dicho perfil; procedimiento de identificacion del perfil; uso de sonda para identificar la expresion diferencial de al menos un gen de actInfo
- Publication number
- CL2007001571A1 CL2007001571A1 CL200701571A CL2007001571A CL2007001571A1 CL 2007001571 A1 CL2007001571 A1 CL 2007001571A1 CL 200701571 A CL200701571 A CL 200701571A CL 2007001571 A CL2007001571 A CL 2007001571A CL 2007001571 A1 CL2007001571 A1 CL 2007001571A1
- Authority
- CL
- Chile
- Prior art keywords
- profile
- immunotherapy
- probe
- differential expression
- identification procedure
- Prior art date
Links
- 238000009169 immunotherapy Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Public Health (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0610949A GB0610949D0 (en) | 2006-06-02 | 2006-06-02 | Method |
| GB0700761A GB0700761D0 (en) | 2007-01-15 | 2007-01-15 | Method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2007001571A1 true CL2007001571A1 (es) | 2008-05-16 |
Family
ID=38801855
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL200701571A CL2007001571A1 (es) | 2006-06-02 | 2007-05-31 | Perfil genico indicativo de probabilidad aumentada de que un paciente responda o no a una inmunoterapia; uso de dicho perfil; procedimiento de identificacion del perfil; uso de sonda para identificar la expresion diferencial de al menos un gen de act |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20100021424A1 (enExample) |
| EP (23) | EP2390357A1 (enExample) |
| JP (1) | JP2009538607A (enExample) |
| KR (1) | KR20090017655A (enExample) |
| AR (1) | AR061136A1 (enExample) |
| AU (1) | AU2007256383B2 (enExample) |
| BR (1) | BRPI0712497A2 (enExample) |
| CA (1) | CA2653949A1 (enExample) |
| CL (1) | CL2007001571A1 (enExample) |
| EA (1) | EA200802242A1 (enExample) |
| ES (1) | ES2539042T3 (enExample) |
| MX (1) | MX2008015372A (enExample) |
| PE (1) | PE20080742A1 (enExample) |
| TW (1) | TW200817680A (enExample) |
| WO (1) | WO2007140958A2 (enExample) |
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| WO2009068621A1 (en) * | 2007-11-30 | 2009-06-04 | Glaxosmithkline Biologicals S.A. | Method for classifying cancer patients as responder or non-responder to immunotherapy |
| GB0816867D0 (en) * | 2008-09-15 | 2008-10-22 | Glaxosmithkline Biolog Sa | Method |
| GB2466025A (en) * | 2008-12-08 | 2010-06-09 | Univ Francois Rabelais De Tour | C3/ITGAM polymorphisms and cancer prognosis |
| GB0917457D0 (en) * | 2009-10-06 | 2009-11-18 | Glaxosmithkline Biolog Sa | Method |
| JP5706913B2 (ja) * | 2009-12-16 | 2015-04-22 | 日立化成株式会社 | 攻撃的及び防御的免疫マーカーのexvivo誘導により宿主免疫機能を特徴付けるための方法 |
| EP2380991A1 (en) | 2010-04-20 | 2011-10-26 | Universitätsklinikum Hamburg-Eppendorf | Method of determining the metastatic potential of a tumor |
| EA201390370A1 (ru) * | 2010-09-15 | 2013-07-30 | Олмак Дайэгностикс Лимитед | Молекулярно-диагностический тест для определения онкологического заболевания |
| KR101287600B1 (ko) * | 2011-01-04 | 2013-07-18 | 주식회사 젠큐릭스 | 초기유방암의 예후 예측용 유전자 및 이를 이용한 초기유방암의 예후예측 방법 |
| US9926604B2 (en) | 2011-10-14 | 2018-03-27 | The Regents Of The University Of California | Multiplex PCR-based testing of cutaneous squamous cell carcinoma and pseudoepitheliomatous hyperplasia and methods for distinguishing the same |
| WO2014009535A2 (en) * | 2012-07-12 | 2014-01-16 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for predicting the survival time and treatment responsiveness of a patient suffering from a solid cancer with a signature of at least 7 genes |
| JO3519B1 (ar) | 2013-01-25 | 2020-07-05 | Amgen Inc | تركيبات أجسام مضادة لأجل cdh19 و cd3 |
| US10801070B2 (en) | 2013-11-25 | 2020-10-13 | The Broad Institute, Inc. | Compositions and methods for diagnosing, evaluating and treating cancer |
| US11725237B2 (en) | 2013-12-05 | 2023-08-15 | The Broad Institute Inc. | Polymorphic gene typing and somatic change detection using sequencing data |
| NZ721908A (en) | 2013-12-20 | 2022-12-23 | Massachusetts Gen Hospital | Combination therapy with neoantigen vaccine |
| AU2015283869B2 (en) * | 2014-07-03 | 2020-04-02 | University Of Virginia Patent Foundation | Systems and methods for identifying and profiling muscle patterns |
| US20170298443A1 (en) * | 2014-09-25 | 2017-10-19 | Moffitt Genetics Corporation | Prognostic tumor biomarkers |
| EP4636401A2 (en) | 2014-12-19 | 2025-10-22 | The Broad Institute, Inc. | Methods for profiling the t-cell-receptor repertoire |
| US10975442B2 (en) | 2014-12-19 | 2021-04-13 | Massachusetts Institute Of Technology | Molecular biomarkers for cancer immunotherapy |
| JP6489900B2 (ja) * | 2015-03-30 | 2019-03-27 | 株式会社ジャパンディスプレイ | 入力装置及び表示装置 |
| CA2986235A1 (en) | 2015-05-20 | 2016-11-24 | The Broad Institute, Inc. | Shared neoantigens |
| WO2017011623A1 (en) * | 2015-07-14 | 2017-01-19 | Atossa Genetics Inc. | Transpapillary methods and compositions for treating breast disorders |
| JP6624704B2 (ja) | 2015-08-31 | 2019-12-25 | 日立化成株式会社 | 尿路上皮疾患の評価のための分子法 |
| US11549149B2 (en) | 2017-01-24 | 2023-01-10 | The Broad Institute, Inc. | Compositions and methods for detecting a mutant variant of a polynucleotide |
| JP7457642B2 (ja) | 2017-04-03 | 2024-03-28 | ビオンテック ユーエス インコーポレイテッド | タンパク質抗原およびその使用 |
| US11793867B2 (en) | 2017-12-18 | 2023-10-24 | Biontech Us Inc. | Neoantigens and uses thereof |
| WO2019246286A1 (en) | 2018-06-19 | 2019-12-26 | Neon Therapeutics, Inc. | Neoantigens and uses thereof |
| GB201908565D0 (en) * | 2019-06-14 | 2019-07-31 | Cray Innovation Ab | Method of stratifying subjects into sub-groups for therapeutic treatment |
| CN114540504B (zh) * | 2022-04-27 | 2022-07-08 | 广州万德基因医学科技有限公司 | 用于预测肺鳞癌患者免疫疗效的标志物组及系统 |
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-
2007
- 2007-05-31 TW TW096119645A patent/TW200817680A/zh unknown
- 2007-05-31 EP EP11163252A patent/EP2390357A1/en not_active Withdrawn
- 2007-05-31 EP EP11163264A patent/EP2390360A1/en not_active Withdrawn
- 2007-05-31 ES ES10159376.2T patent/ES2539042T3/es active Active
- 2007-05-31 EA EA200802242A patent/EA200802242A1/ru unknown
- 2007-05-31 JP JP2009512510A patent/JP2009538607A/ja active Pending
- 2007-05-31 EP EP11163713A patent/EP2390363A1/en not_active Withdrawn
- 2007-05-31 CL CL200701571A patent/CL2007001571A1/es unknown
- 2007-05-31 AR ARP070102352A patent/AR061136A1/es not_active Application Discontinuation
- 2007-05-31 EP EP11162329A patent/EP2392673A1/en not_active Withdrawn
- 2007-05-31 EP EP11163719A patent/EP2390366A1/en not_active Withdrawn
- 2007-05-31 EP EP11163268A patent/EP2392675A1/en not_active Withdrawn
- 2007-05-31 EP EP11163716A patent/EP2390364A1/en not_active Withdrawn
- 2007-05-31 EP EP07725789A patent/EP2032719A2/en not_active Withdrawn
- 2007-05-31 EP EP11163271A patent/EP2390361A1/en not_active Withdrawn
- 2007-05-31 CA CA002653949A patent/CA2653949A1/en not_active Abandoned
- 2007-05-31 EP EP11162324A patent/EP2390353A1/en not_active Withdrawn
- 2007-05-31 EP EP11162327A patent/EP2390356A1/en not_active Withdrawn
- 2007-05-31 PE PE2007000676A patent/PE20080742A1/es not_active Application Discontinuation
- 2007-05-31 EP EP11163717A patent/EP2390365A1/en not_active Withdrawn
- 2007-05-31 EP EP11162326A patent/EP2390355A1/en not_active Withdrawn
- 2007-05-31 US US12/303,213 patent/US20100021424A1/en not_active Abandoned
- 2007-05-31 EP EP11163261A patent/EP2390358A1/en not_active Withdrawn
- 2007-05-31 EP EP10159376.2A patent/EP2258874B1/en active Active
- 2007-05-31 AU AU2007256383A patent/AU2007256383B2/en not_active Ceased
- 2007-05-31 EP EP11162320A patent/EP2392671A1/en not_active Withdrawn
- 2007-05-31 EP EP11163726A patent/EP2390369A1/en not_active Withdrawn
- 2007-05-31 WO PCT/EP2007/004915 patent/WO2007140958A2/en not_active Ceased
- 2007-05-31 EP EP11163722A patent/EP2390368A1/en not_active Withdrawn
- 2007-05-31 EP EP11162323A patent/EP2392672A1/en not_active Withdrawn
- 2007-05-31 BR BRPI0712497-0A patent/BRPI0712497A2/pt not_active IP Right Cessation
- 2007-05-31 EP EP11163277A patent/EP2390362A1/en not_active Withdrawn
- 2007-05-31 EP EP11163263A patent/EP2390359A1/en not_active Withdrawn
- 2007-05-31 EP EP11163720A patent/EP2390367A1/en not_active Withdrawn
- 2007-05-31 EP EP11162325A patent/EP2390354A1/en not_active Withdrawn
- 2007-05-31 MX MX2008015372A patent/MX2008015372A/es not_active Application Discontinuation
- 2007-05-31 KR KR1020087031950A patent/KR20090017655A/ko not_active Ceased
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