JP2009538359A5 - - Google Patents
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- Publication number
- JP2009538359A5 JP2009538359A5 JP2009513381A JP2009513381A JP2009538359A5 JP 2009538359 A5 JP2009538359 A5 JP 2009538359A5 JP 2009513381 A JP2009513381 A JP 2009513381A JP 2009513381 A JP2009513381 A JP 2009513381A JP 2009538359 A5 JP2009538359 A5 JP 2009538359A5
- Authority
- JP
- Japan
- Prior art keywords
- pain
- enantiomer
- compound
- group
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 CC(C1OC1)c1ccc(CC(C)(C)*)cc1 Chemical compound CC(C1OC1)c1ccc(CC(C)(C)*)cc1 0.000 description 229
- CYWFCPPBTWOZSF-UHFFFAOYSA-N CC(C)Cc1ccc(CC(O)=O)cc1 Chemical compound CC(C)Cc1ccc(CC(O)=O)cc1 CYWFCPPBTWOZSF-UHFFFAOYSA-N 0.000 description 2
- IYSPYQQBEYOGFI-UHFFFAOYSA-N CC(C)(C(O)=O)c1ccc(cc(cc2)OC)c2c1 Chemical compound CC(C)(C(O)=O)c1ccc(cc(cc2)OC)c2c1 IYSPYQQBEYOGFI-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80910706P | 2006-05-26 | 2006-05-26 | |
| US84136706P | 2006-08-30 | 2006-08-30 | |
| PCT/US2007/069480 WO2007140189A2 (en) | 2006-05-26 | 2007-05-22 | Preparation and utility of substituted carboxylic acid compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009538359A JP2009538359A (ja) | 2009-11-05 |
| JP2009538359A5 true JP2009538359A5 (enExample) | 2010-07-08 |
Family
ID=38779326
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009513381A Pending JP2009538359A (ja) | 2006-05-26 | 2007-05-22 | 置換カルボン酸化合物の製造および利用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20070276042A1 (enExample) |
| EP (1) | EP2020849A2 (enExample) |
| JP (1) | JP2009538359A (enExample) |
| AU (1) | AU2007267612A1 (enExample) |
| BR (1) | BRPI0711228A2 (enExample) |
| CA (1) | CA2653262A1 (enExample) |
| WO (1) | WO2007140189A2 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20022394A1 (it) * | 2002-11-13 | 2004-05-14 | Bracco Spa | Uso di triiodotironina 3-solfato come farmaco ad attivita' tireomimetica e relative formulazioni farmaceutiche. |
| ITMI20110713A1 (it) | 2011-04-29 | 2012-10-30 | Bracco Imaging Spa | Processo per la preparazione di un derivato solfatato di3,5-diiodo-o-[3-iodofenil]-l-tirosina |
| CN102149280B (zh) | 2008-07-15 | 2017-05-24 | 泰拉科斯有限公司 | 氘化苄基苯衍生物及其使用方法 |
| CN102020521A (zh) * | 2009-09-10 | 2011-04-20 | 陈松源 | 氘代中药单体的制备方法和应用 |
| CN102020522A (zh) * | 2009-09-21 | 2011-04-20 | 陈松源 | 氘代药物的制备方法和应用 |
| JP6191325B2 (ja) * | 2012-08-10 | 2017-09-06 | 和光純薬工業株式会社 | 芳香族化合物の重水素化方法 |
| CN102795991B (zh) * | 2012-08-25 | 2014-07-23 | 神威药业集团有限公司 | 2-戊酰基-1,5-环己二烯-1-羧酸及其合成方法和应用 |
| FR2997856B1 (fr) * | 2012-11-14 | 2015-04-24 | Pf Medicament | Pastille medicamenteuse a base d'ibuprofene sodique dihydrate |
| TWI689490B (zh) * | 2013-03-15 | 2020-04-01 | 英商邊緣生物科技有限公司 | 用於治療纖維化之經取代之芳族化合物及相關方法 |
| WO2017070448A1 (en) * | 2015-10-22 | 2017-04-27 | The Trustees Of The University Of Pennsylvania | 2-beta-naphthyl-acetic acid analogs as akr1c3 inhibitors and methods of using same |
| US11731947B2 (en) | 2019-04-10 | 2023-08-22 | University Of Notre Dame Du Lac | Deuterated antimicrobial compounds |
| EP4452244A4 (en) * | 2021-12-21 | 2026-02-18 | Biojiva Llc | ANTI-INFLAMMATORY METHODS INVOLVING SITE-SPECIFIC COMPOSITIONS COMPRISING ISOTOPICALLY MODIFIED FATTY ACIDS |
| CN114933516B (zh) * | 2022-06-17 | 2024-01-30 | 句容宁武新材料股份有限公司 | 一种在离子液体介质中合成氘代化合物的方法 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4567183A (en) * | 1983-03-11 | 1986-01-28 | Analgesic Associates | Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same |
| US5093086A (en) * | 1988-12-23 | 1992-03-03 | Gte Products Corporation | Packed bed reactor for photochemical 196 Hg isotope separation |
| IE66933B1 (en) * | 1990-01-15 | 1996-02-07 | Elan Corp Plc | Controlled absorption naproxen formulation for once-daily administration |
| ES2293638T3 (es) * | 1994-03-25 | 2008-03-16 | Isotechnika, Inc. | Mejora de la eficacia de farmacos por deuteracion. |
| US6221335B1 (en) * | 1994-03-25 | 2001-04-24 | Isotechnika, Inc. | Method of using deuterated calcium channel blockers |
| US6334997B1 (en) * | 1994-03-25 | 2002-01-01 | Isotechnika, Inc. | Method of using deuterated calcium channel blockers |
| JP3985874B2 (ja) * | 1994-11-11 | 2007-10-03 | クラシエ製薬株式会社 | 感冒治療薬 |
| US6348216B1 (en) * | 1996-06-10 | 2002-02-19 | Knoll Pharmaceutical Company | Ibuprofen and narcotic analgesic compositions |
| US6361794B1 (en) * | 1996-06-12 | 2002-03-26 | Basf Corporation | Method of making ibuprofen and narcotic analgesic composition |
| US5872145A (en) * | 1996-08-16 | 1999-02-16 | Pozen, Inc. | Formulation of 5-HT agonist and NSAID for treatment of migraine |
| US6586458B1 (en) * | 1996-08-16 | 2003-07-01 | Pozen Inc. | Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs |
| US6884429B2 (en) * | 1997-09-05 | 2005-04-26 | Isotechnika International Inc. | Medical devices incorporating deuterated rapamycin for controlled delivery thereof |
| US6440710B1 (en) * | 1998-12-10 | 2002-08-27 | The Scripps Research Institute | Antibody-catalyzed deuteration, tritiation, dedeuteration or detritiation of carbonyl compounds |
| EP1104760B1 (en) * | 1999-12-03 | 2003-03-12 | Pfizer Products Inc. | Sulfamoylheteroaryl pyrazole compounds as anti-inflammatory/analgesic agents |
| EP1134290A3 (en) * | 2000-03-14 | 2004-01-02 | Pfizer Products Inc. | Pharmacophore models for the identification of the CYP2D6 inhibitory potency of selective serotonin reuptake inhibitors |
| US6342530B1 (en) * | 2000-11-14 | 2002-01-29 | Farmacon-Il, Llc | Composition and method for parenteral administration of ibuprofen d,l- or l-lysine salt |
| US6344479B1 (en) * | 2001-03-20 | 2002-02-05 | Farmacon-Il, Llc | Method of preventing retinopathy of prematurity in a neonate |
| US6727286B2 (en) * | 2001-11-02 | 2004-04-27 | Cumberland Pharmaceuticals Inc. | Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid |
| DE10162120A1 (de) * | 2001-12-12 | 2003-06-18 | Berolina Drug Dev Ab Svedala | Deuterierte substituierte Dihydrofuranone sowie diese Verbindungen enthaltende Arzneimittel |
| DE10224888A1 (de) * | 2002-06-05 | 2003-12-24 | Merck Patent Gmbh | Pyridazinderivate |
| WO2003104166A1 (ja) * | 2002-06-06 | 2003-12-18 | 和光純薬工業株式会社 | 不活性メチレンの重水素化方法 |
| RU2331649C2 (ru) * | 2002-06-20 | 2008-08-20 | Ай-Си Ви-И-Си Лимитед | Серосодержащие фосфолипидные производные, содержащая их фармацевтическая композиция, их применение для лечения заболеваний и способ их получения |
| TW200413273A (en) * | 2002-11-15 | 2004-08-01 | Wako Pure Chem Ind Ltd | Heavy hydrogenation method of heterocyclic rings |
| EP1575566B1 (en) * | 2002-12-26 | 2012-02-22 | Pozen, Inc. | Multilayer dosage forms containing naproxen and triptans |
| US20080033011A1 (en) * | 2005-07-29 | 2008-02-07 | Concert Pharmaceuticals Inc. | Novel benzo[d][1,3]-dioxol derivatives |
| CA2624179A1 (en) * | 2005-10-06 | 2007-04-12 | Auspex Pharmaceuticals, Inc. | Deuterated inhibitors of gastric h+, k+-atpase with enhanced therapeutic properties |
| US7750168B2 (en) * | 2006-02-10 | 2010-07-06 | Sigma-Aldrich Co. | Stabilized deuteroborane-tetrahydrofuran complex |
| US20090062364A1 (en) * | 2007-08-29 | 2009-03-05 | Protia, Llc | Deuterium-enriched celecoxib |
| US20090076150A1 (en) * | 2007-09-15 | 2009-03-19 | Protia, Llc | Deuterium-enriched bromfenac |
| US20090076087A1 (en) * | 2007-09-17 | 2009-03-19 | Protia, Llc | Deuterium-enriched etoricoxib |
| US20090082452A1 (en) * | 2007-09-26 | 2009-03-26 | Protia, Llc | Deuterium-enriched lumiracoxib |
| US20090082450A1 (en) * | 2007-09-26 | 2009-03-26 | Protia, Llc | Deuterium-enriched diclofenac |
-
2007
- 2007-05-22 WO PCT/US2007/069480 patent/WO2007140189A2/en not_active Ceased
- 2007-05-22 JP JP2009513381A patent/JP2009538359A/ja active Pending
- 2007-05-22 US US11/752,238 patent/US20070276042A1/en not_active Abandoned
- 2007-05-22 EP EP07784044A patent/EP2020849A2/en not_active Withdrawn
- 2007-05-22 BR BRPI0711228-9A patent/BRPI0711228A2/pt not_active IP Right Cessation
- 2007-05-22 CA CA002653262A patent/CA2653262A1/en not_active Abandoned
- 2007-05-22 AU AU2007267612A patent/AU2007267612A1/en not_active Abandoned
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