JP2009538359A - 置換カルボン酸化合物の製造および利用 - Google Patents

置換カルボン酸化合物の製造および利用 Download PDF

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Publication number
JP2009538359A
JP2009538359A JP2009513381A JP2009513381A JP2009538359A JP 2009538359 A JP2009538359 A JP 2009538359A JP 2009513381 A JP2009513381 A JP 2009513381A JP 2009513381 A JP2009513381 A JP 2009513381A JP 2009538359 A JP2009538359 A JP 2009538359A
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enantiomer
pain
compound
mixture
group
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Japanese (ja)
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JP2009538359A5 (enExample
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トーマス・ジー・ガント
セパー・サーシャー
ウ・ソンヒュン
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Auspex Pharmaceuticals Inc
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Auspex Pharmaceuticals Inc
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/04Drugs for disorders of the respiratory system for throat disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/38Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic
    • C07C57/40Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic containing condensed ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05Isotopically modified compounds, e.g. labelled

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Otolaryngology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
JP2009513381A 2006-05-26 2007-05-22 置換カルボン酸化合物の製造および利用 Pending JP2009538359A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80910706P 2006-05-26 2006-05-26
US84136706P 2006-08-30 2006-08-30
PCT/US2007/069480 WO2007140189A2 (en) 2006-05-26 2007-05-22 Preparation and utility of substituted carboxylic acid compounds

Publications (2)

Publication Number Publication Date
JP2009538359A true JP2009538359A (ja) 2009-11-05
JP2009538359A5 JP2009538359A5 (enExample) 2010-07-08

Family

ID=38779326

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JP2009513381A Pending JP2009538359A (ja) 2006-05-26 2007-05-22 置換カルボン酸化合物の製造および利用

Country Status (7)

Country Link
US (1) US20070276042A1 (enExample)
EP (1) EP2020849A2 (enExample)
JP (1) JP2009538359A (enExample)
AU (1) AU2007267612A1 (enExample)
BR (1) BRPI0711228A2 (enExample)
CA (1) CA2653262A1 (enExample)
WO (1) WO2007140189A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014111561A (ja) * 2012-08-10 2014-06-19 Wako Pure Chem Ind Ltd 芳香族化合物の重水素化方法
JP2015537019A (ja) * 2012-11-14 2015-12-24 ピエール、ファーブル、メディカマン イブプロフェンナトリウム二水和物に基づく薬用トローチ

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ITMI20110713A1 (it) 2011-04-29 2012-10-30 Bracco Imaging Spa Processo per la preparazione di un derivato solfatato di3,5-diiodo-o-[3-iodofenil]-l-tirosina
ITMI20022394A1 (it) * 2002-11-13 2004-05-14 Bracco Spa Uso di triiodotironina 3-solfato come farmaco ad attivita' tireomimetica e relative formulazioni farmaceutiche.
US9061060B2 (en) 2008-07-15 2015-06-23 Theracos Inc. Deuterated benzylbenzene derivatives and methods of use
CN102020521A (zh) * 2009-09-10 2011-04-20 陈松源 氘代中药单体的制备方法和应用
CN102020522A (zh) * 2009-09-21 2011-04-20 陈松源 氘代药物的制备方法和应用
CN102795991B (zh) * 2012-08-25 2014-07-23 神威药业集团有限公司 2-戊酰基-1,5-环己二烯-1-羧酸及其合成方法和应用
TWI689490B (zh) * 2013-03-15 2020-04-01 英商邊緣生物科技有限公司 用於治療纖維化之經取代之芳族化合物及相關方法
US11459295B2 (en) * 2015-10-22 2022-10-04 The Trustees Of The University Of Pennsylvania 2-beta-naphthyl-acetic acid analogs as AKR1C3 inhibitors and methods of using same
US11731947B2 (en) 2019-04-10 2023-08-22 University Of Notre Dame Du Lac Deuterated antimicrobial compounds
CN114933516B (zh) * 2022-06-17 2024-01-30 句容宁武新材料股份有限公司 一种在离子液体介质中合成氘代化合物的方法

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JPH08208465A (ja) * 1994-11-11 1996-08-13 Kanebo Ltd 感冒治療薬
JP2005529969A (ja) * 2002-06-20 2005-10-06 アイシー・ベック・リミテッド 含硫黄ホスホリピド誘導体
JP2005534660A (ja) * 2002-06-05 2005-11-17 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング ピリダジン誘導体
JP2006512943A (ja) * 2002-11-20 2006-04-20 アイソテクニカ, インターナショナル インコーポレイテッド 重水素化ラパマイシンの制御された送達のための、重水素化ラパマイシンを組み込む医療用デバイス

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US5093086A (en) * 1988-12-23 1992-03-03 Gte Products Corporation Packed bed reactor for photochemical 196 Hg isotope separation
IE66933B1 (en) * 1990-01-15 1996-02-07 Elan Corp Plc Controlled absorption naproxen formulation for once-daily administration
US6334997B1 (en) * 1994-03-25 2002-01-01 Isotechnika, Inc. Method of using deuterated calcium channel blockers
JP3696884B2 (ja) * 1994-03-25 2005-09-21 アイソテクニカ、インコーポレーテッド ジュウテリウム化による薬物の効能の増強
US6221335B1 (en) * 1994-03-25 2001-04-24 Isotechnika, Inc. Method of using deuterated calcium channel blockers
US6348216B1 (en) * 1996-06-10 2002-02-19 Knoll Pharmaceutical Company Ibuprofen and narcotic analgesic compositions
US6361794B1 (en) * 1996-06-12 2002-03-26 Basf Corporation Method of making ibuprofen and narcotic analgesic composition
US5872145A (en) * 1996-08-16 1999-02-16 Pozen, Inc. Formulation of 5-HT agonist and NSAID for treatment of migraine
US6586458B1 (en) * 1996-08-16 2003-07-01 Pozen Inc. Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
US6440710B1 (en) * 1998-12-10 2002-08-27 The Scripps Research Institute Antibody-catalyzed deuteration, tritiation, dedeuteration or detritiation of carbonyl compounds
EP1104760B1 (en) * 1999-12-03 2003-03-12 Pfizer Products Inc. Sulfamoylheteroaryl pyrazole compounds as anti-inflammatory/analgesic agents
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US6344479B1 (en) * 2001-03-20 2002-02-05 Farmacon-Il, Llc Method of preventing retinopathy of prematurity in a neonate
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DE10162120A1 (de) * 2001-12-12 2003-06-18 Berolina Drug Dev Ab Svedala Deuterierte substituierte Dihydrofuranone sowie diese Verbindungen enthaltende Arzneimittel
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TW200413273A (en) * 2002-11-15 2004-08-01 Wako Pure Chem Ind Ltd Heavy hydrogenation method of heterocyclic rings
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JPH08208465A (ja) * 1994-11-11 1996-08-13 Kanebo Ltd 感冒治療薬
JP2005534660A (ja) * 2002-06-05 2005-11-17 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング ピリダジン誘導体
JP2005529969A (ja) * 2002-06-20 2005-10-06 アイシー・ベック・リミテッド 含硫黄ホスホリピド誘導体
JP2006512943A (ja) * 2002-11-20 2006-04-20 アイソテクニカ, インターナショナル インコーポレイテッド 重水素化ラパマイシンの制御された送達のための、重水素化ラパマイシンを組み込む医療用デバイス

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014111561A (ja) * 2012-08-10 2014-06-19 Wako Pure Chem Ind Ltd 芳香族化合物の重水素化方法
JP2015537019A (ja) * 2012-11-14 2015-12-24 ピエール、ファーブル、メディカマン イブプロフェンナトリウム二水和物に基づく薬用トローチ

Also Published As

Publication number Publication date
BRPI0711228A2 (pt) 2012-06-19
WO2007140189A3 (en) 2008-02-07
EP2020849A2 (en) 2009-02-11
US20070276042A1 (en) 2007-11-29
WO2007140189A2 (en) 2007-12-06
CA2653262A1 (en) 2007-12-06
AU2007267612A1 (en) 2007-12-06

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