JP2010512343A5 - - Google Patents
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- Publication number
- JP2010512343A5 JP2010512343A5 JP2009540513A JP2009540513A JP2010512343A5 JP 2010512343 A5 JP2010512343 A5 JP 2010512343A5 JP 2009540513 A JP2009540513 A JP 2009540513A JP 2009540513 A JP2009540513 A JP 2009540513A JP 2010512343 A5 JP2010512343 A5 JP 2010512343A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- compared
- isotopically enriched
- deuterium
- plasma concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 0 CCCCCCOC(CC*CC)(*(CC)CC)*(C(*)(**CC)c1c(c(*(CC)CC)c(*CC)c(*CC)c2N(CC)P)c2c(CCC)c(C(C)*[Cn])c1*(CC)CC)C(*CC)(C(C)*CC)C(*CC)=C(C#CC(C(CC*C)(*(CC)CC)*(C)(C)CC)(C(*CC)(*CC)C(C)*N)C(*CC)(C(C)*[Np])*(*)CC)N(CC)CCC Chemical compound CCCCCCOC(CC*CC)(*(CC)CC)*(C(*)(**CC)c1c(c(*(CC)CC)c(*CC)c(*CC)c2N(CC)P)c2c(CCC)c(C(C)*[Cn])c1*(CC)CC)C(*CC)(C(C)*CC)C(*CC)=C(C#CC(C(CC*C)(*(CC)CC)*(C)(C)CC)(C(*CC)(*CC)C(C)*N)C(*CC)(C(C)*[Np])*(*)CC)N(CC)CCC 0.000 description 30
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86930906P | 2006-12-08 | 2006-12-08 | |
| PCT/US2007/086917 WO2008073863A2 (en) | 2006-12-08 | 2007-12-10 | Preparation and utility of substituted allylamines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010512343A JP2010512343A (ja) | 2010-04-22 |
| JP2010512343A5 true JP2010512343A5 (enExample) | 2010-06-03 |
Family
ID=39402913
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009540513A Withdrawn JP2010512343A (ja) | 2006-12-08 | 2007-12-10 | 置換アリルアミン類の調製および実用性 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20080167312A1 (enExample) |
| EP (1) | EP2121572A2 (enExample) |
| JP (1) | JP2010512343A (enExample) |
| WO (1) | WO2008073863A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2926813B1 (fr) * | 2008-01-28 | 2011-10-21 | Inst Francais Du Petrole | Procede de separation du propane et du propylene mettant en oeuvre une colonne a distiller et une unite de separation par membrane |
| CN102149280B (zh) | 2008-07-15 | 2017-05-24 | 泰拉科斯有限公司 | 氘化苄基苯衍生物及其使用方法 |
| WO2010028015A2 (en) * | 2008-09-03 | 2010-03-11 | Auspex Pharmaceuticals, Inc | 2-oxo-1,2-dihydro-quinoline modulators of immune function |
| CN102869775A (zh) | 2009-09-30 | 2013-01-09 | 哈佛大学校长及研究员协会 | 通过调节自噬抑制基因产物调节自噬的方法 |
| CN106414392B (zh) * | 2014-06-10 | 2019-05-14 | 华东理工大学 | 6,7,8,9-四氢-5h-苯并[7]轮烯-2-烷基胺类化合物及其用途 |
| CN105016966A (zh) * | 2015-07-31 | 2015-11-04 | 江苏恒润制药有限公司 | 一种（e）-1-氯-6,6-二甲基-2-庚烯-4-炔的制备方法 |
| CN111514860B (zh) * | 2020-05-09 | 2022-12-30 | 江南大学 | 一种羊毛废弃物的高效综合回收再利用方法 |
| CN114380696B (zh) * | 2021-12-23 | 2022-11-25 | 山东诚汇双达药业有限公司 | 一种盐酸特比萘芬的制备方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE10272T1 (de) * | 1979-08-22 | 1984-11-15 | Sandoz Ag | Propenylamine, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zusammensetzungen und ihre verwendung als arzneimittel. |
| US4870095A (en) * | 1988-06-13 | 1989-09-26 | Sterling Drug, Inc. | 1H-pyrazole-1-alkanamides, antiarrhythmic compositions and use |
| HU223343B1 (hu) * | 1991-05-20 | 2004-06-28 | Novartis Ag. | Allil-amin-származékot tartalmazó gyógyászati készítmények és eljárás azok előállítására |
| US6221335B1 (en) * | 1994-03-25 | 2001-04-24 | Isotechnika, Inc. | Method of using deuterated calcium channel blockers |
| GB9509631D0 (en) * | 1995-05-12 | 1995-07-05 | Sandoz Ltd | Antifungal combination |
| US6440710B1 (en) * | 1998-12-10 | 2002-08-27 | The Scripps Research Institute | Antibody-catalyzed deuteration, tritiation, dedeuteration or detritiation of carbonyl compounds |
| EP1104760B1 (en) * | 1999-12-03 | 2003-03-12 | Pfizer Products Inc. | Sulfamoylheteroaryl pyrazole compounds as anti-inflammatory/analgesic agents |
| EP1134290A3 (en) * | 2000-03-14 | 2004-01-02 | Pfizer Products Inc. | Pharmacophore models for the identification of the CYP2D6 inhibitory potency of selective serotonin reuptake inhibitors |
| DE10162121A1 (de) * | 2001-12-12 | 2003-06-18 | Berolina Drug Dev Ab Svedala | Deuterierte substituierte Pyrazolyl-Benzolsulfonamide sowie diese Verbindungen enthaltende Arzneimittel |
| TW200413273A (en) * | 2002-11-15 | 2004-08-01 | Wako Pure Chem Ind Ltd | Heavy hydrogenation method of heterocyclic rings |
| US20080033011A1 (en) * | 2005-07-29 | 2008-02-07 | Concert Pharmaceuticals Inc. | Novel benzo[d][1,3]-dioxol derivatives |
| US7514068B2 (en) * | 2005-09-14 | 2009-04-07 | Concert Pharmaceuticals Inc. | Biphenyl-pyrazolecarboxamide compounds |
| US7750168B2 (en) * | 2006-02-10 | 2010-07-06 | Sigma-Aldrich Co. | Stabilized deuteroborane-tetrahydrofuran complex |
| US20090082469A1 (en) * | 2007-09-26 | 2009-03-26 | Protia, Llc | Deuterium-enriched terbinafine |
-
2007
- 2007-12-10 WO PCT/US2007/086917 patent/WO2008073863A2/en not_active Ceased
- 2007-12-10 EP EP07865444A patent/EP2121572A2/en not_active Withdrawn
- 2007-12-10 JP JP2009540513A patent/JP2010512343A/ja not_active Withdrawn
- 2007-12-10 US US11/953,195 patent/US20080167312A1/en not_active Abandoned
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