JP2009536147A5 - - Google Patents

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Publication number
JP2009536147A5
JP2009536147A5 JP2008549611A JP2008549611A JP2009536147A5 JP 2009536147 A5 JP2009536147 A5 JP 2009536147A5 JP 2008549611 A JP2008549611 A JP 2008549611A JP 2008549611 A JP2008549611 A JP 2008549611A JP 2009536147 A5 JP2009536147 A5 JP 2009536147A5
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JP
Japan
Prior art keywords
tablet
pain
subject
minutes
transmucosal administration
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Pending
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JP2008549611A
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English (en)
Japanese (ja)
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JP2009536147A (ja
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Priority claimed from US11/650,227 external-priority patent/US8252328B2/en
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Publication of JP2009536147A publication Critical patent/JP2009536147A/ja
Publication of JP2009536147A5 publication Critical patent/JP2009536147A5/ja
Pending legal-status Critical Current

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JP2008549611A 2006-01-06 2007-01-08 経口経粘膜送達用の生体接着性薬調合物 Pending JP2009536147A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US75693706P 2006-01-06 2006-01-06
US81873006P 2006-07-06 2006-07-06
US86056906P 2006-11-22 2006-11-22
US11/650,227 US8252328B2 (en) 2006-01-06 2007-01-05 Bioadhesive drug formulations for oral transmucosal delivery
PCT/US2007/000528 WO2007081948A2 (en) 2006-01-06 2007-01-08 Bioadhesive drug formulations for oral transmucosal delivery

Publications (2)

Publication Number Publication Date
JP2009536147A JP2009536147A (ja) 2009-10-08
JP2009536147A5 true JP2009536147A5 (enExample) 2013-02-14

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Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008549611A Pending JP2009536147A (ja) 2006-01-06 2007-01-08 経口経粘膜送達用の生体接着性薬調合物

Country Status (6)

Country Link
US (1) US8252328B2 (enExample)
EP (1) EP1968554A4 (enExample)
JP (1) JP2009536147A (enExample)
KR (1) KR20080084858A (enExample)
CA (1) CA2636119A1 (enExample)
WO (1) WO2007081948A2 (enExample)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020119187A1 (en) * 2000-09-29 2002-08-29 Cantor Adam S. Composition for the transdermal delivery of fentanyl
CN100508974C (zh) * 2001-03-16 2009-07-08 阿尔扎公司 施用芬太尼的经皮贴剂
US20050208117A1 (en) * 2001-03-16 2005-09-22 Venkatraman Subramanian S Transdermal administration of fentanyl and analogs thereof
US8535714B2 (en) 2006-01-06 2013-09-17 Acelrx Pharmaceuticals, Inc. Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
US8753308B2 (en) 2006-01-06 2014-06-17 Acelrx Pharmaceuticals, Inc. Methods for administering small volume oral transmucosal dosage forms using a dispensing device
US9066847B2 (en) 2007-01-05 2015-06-30 Aceirx Pharmaceuticals, Inc. Storage and dispensing devices for administration of oral transmucosal dosage forms
US8865743B2 (en) 2006-01-06 2014-10-21 Acelrx Pharmaceuticals, Inc. Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
US8252329B2 (en) 2007-01-05 2012-08-28 Acelrx Pharmaceuticals, Inc. Bioadhesive drug formulations for oral transmucosal delivery
US9289583B2 (en) 2006-01-06 2016-03-22 Acelrx Pharmaceuticals, Inc. Methods for administering small volume oral transmucosal dosage forms using a dispensing device
US8202535B2 (en) 2006-01-06 2012-06-19 Acelrx Pharmaceuticals, Inc. Small-volume oral transmucosal dosage forms
US8357114B2 (en) 2006-01-06 2013-01-22 Acelrx Pharmaceuticals, Inc. Drug dispensing device with flexible push rod
JP2010518086A (ja) * 2007-02-09 2010-05-27 デュレクト コーポレーション スフェンタニルおよびナロキソンを含む経口腔投与製剤
CN101631550A (zh) * 2007-04-02 2010-01-20 东洋纺织株式会社 带状疱疹后神经痛治疗用片剂以及带状疱疹后神经痛的治疗方法
JP5632284B2 (ja) 2007-08-07 2014-11-26 エーセルアールエックス ファーマシューティカルズ, インコーポレイテッド 経口経粘膜剤形を使用する処置時の鎮静および無痛のための組成物および方法
KR101583680B1 (ko) * 2007-10-15 2016-01-08 알자 코퍼레이션 펜타닐의 1일-1회 교체 경피 투여
DE102008014533A1 (de) * 2008-03-15 2009-09-17 Lts Lohmann Therapie-Systeme Ag Gingival-Wafer
US20090286832A1 (en) * 2008-05-15 2009-11-19 Kiichiro Nabeta Narcotic emulsion formulations for treatment of surgical pain
US20100034968A1 (en) * 2008-08-07 2010-02-11 Vector Corporation Polymer coating process using dry glidant in a rotor processor
US20100034967A1 (en) * 2008-08-07 2010-02-11 Vector Corporation Dry polymer layering using a rotor processor
US8807070B2 (en) * 2008-08-07 2014-08-19 Vector Corporation Rotor processor for dry powders
US8945592B2 (en) * 2008-11-21 2015-02-03 Acelrx Pharmaceuticals, Inc. Sufentanil solid dosage forms comprising oxygen scavengers and methods of using the same
WO2010098897A1 (en) * 2009-02-26 2010-09-02 Teikoku Pharma Usa, Inc. Narcotic emulsion formulations for treatment of cancer pain
US8548623B2 (en) 2009-03-18 2013-10-01 Acelrx Pharmaceuticals, Inc. Storage and dispensing devices for administration of oral transmucosal dosage forms
US20110091544A1 (en) * 2009-10-16 2011-04-21 Acelrx Pharmaceuticals, Inc. Compositions and Methods for Mild Sedation, Anxiolysis and Analgesia in the Procedural Setting
DK2563316T3 (da) * 2010-04-30 2019-05-13 Allovate Llc Tandpasta til allergisk desensibilisering via mundslimhinder
WO2011137422A2 (en) 2010-04-30 2011-11-03 Apellis Pharmaceuticals, Inc. Methods and articles for preventing or reducing risk of developing a hyperallergenic immune system
US20110288128A1 (en) 2010-05-21 2011-11-24 Acelrx Pharmaceuticals, Inc. Oral Transmucosal Administration of Sufentanil
MX361757B (es) 2011-09-19 2018-12-13 Orexo Ab Nueva composicion farmaceutica resistente al abuso para el tratamiento de la dependencia de opioides.
PE20142444A1 (es) 2012-05-02 2015-01-09 Orexo Ab Nueva composicion de alfentanilo para el tratamiento del dolor agudo
US9770514B2 (en) 2013-09-03 2017-09-26 ExxPharma Therapeutics LLC Tamper-resistant pharmaceutical dosage forms
NZ732808A (en) 2014-12-23 2021-12-24 Acelrx Pharmaceuticals Inc Systems, devices and methods for dispensing oral transmucosal dosage forms
CN108601916B (zh) 2015-09-10 2021-07-09 英倍尔药业股份有限公司 直列式鼻部递送装置
DK3682915T3 (da) 2015-10-30 2023-06-19 Acelrx Pharmaceuticals Inc Anordning og fremgangsmåder til afgivelse af orale transmucosale doseringsformer
RU2020125871A (ru) 2018-01-05 2022-02-07 Импел Ньюрофарма, Инк. Интраназальная доставка дигидроэрготамина с помощью прецизионного устройства для доставки в обонятельную область
WO2025097068A1 (en) * 2023-11-01 2025-05-08 Entrega Inc. Oral dosage form with ionically chargeable hydrogel for delivery of active agent and permeation enhancer

Family Cites Families (162)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2621655A (en) * 1951-10-11 1952-12-16 Kenneth L Gothard Tablet dispensing gun
US4237884A (en) * 1978-03-17 1980-12-09 Victor Erickson Medication dispenser
US4229447A (en) * 1979-06-04 1980-10-21 American Home Products Corporation Intraoral methods of using benzodiazepines
GB8332556D0 (en) 1983-12-06 1984-01-11 Reckitt & Colmann Prod Ltd Analgesic compositions
US4863737A (en) * 1985-05-01 1989-09-05 University Of Utah Compositions and methods of manufacture of compressed powder medicaments
US5288498A (en) * 1985-05-01 1994-02-22 University Of Utah Research Foundation Compositions of oral nondissolvable matrixes for transmucosal administration of medicaments
US5855908A (en) 1984-05-01 1999-01-05 University Of Utah Research Foundation Non-dissolvable drug-containing dosage-forms for use in the transmucosal delivery of a drug to a patient
DE3421468A1 (de) 1984-06-08 1985-12-19 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim Lipidnanopellets als traegersystem fuer arzneimittel zur peroralen anwendung
US5288497A (en) * 1985-05-01 1994-02-22 The University Of Utah Compositions of oral dissolvable medicaments
US5132114A (en) * 1985-05-01 1992-07-21 University Of Utah Research Foundation Compositions and methods of manufacture of compressed powder medicaments
US5785989A (en) * 1985-05-01 1998-07-28 University Utah Research Foundation Compositions and methods of manufacturing of oral dissolvable medicaments
US5122127A (en) * 1985-05-01 1992-06-16 University Of Utah Apparatus and methods for use in administering medicaments by direct medicament contact to mucosal tissues
US4671953A (en) * 1985-05-01 1987-06-09 University Of Utah Research Foundation Methods and compositions for noninvasive administration of sedatives, analgesics, and anesthetics
FR2619718B1 (fr) * 1987-09-02 1991-07-12 Medibrevex Nouvelles formes galeniques de beta-2-mimetiques pour administration par voie per- et sublinguale
US4873076A (en) * 1988-04-29 1989-10-10 Baker Cummins Pharmaceuticals, Inc. Method of safely providing anesthesia or conscious sedation
US5236714A (en) * 1988-11-01 1993-08-17 Alza Corporation Abusable substance dosage form having reduced abuse potential
US5112616A (en) * 1988-11-30 1992-05-12 Schering Corporation Fast dissolving buccal tablet
US5178878A (en) * 1989-10-02 1993-01-12 Cima Labs, Inc. Effervescent dosage form with microparticles
US5223264A (en) 1989-10-02 1993-06-29 Cima Labs, Inc. Pediatric effervescent dosage form
GB9015522D0 (en) * 1990-07-13 1990-08-29 Braithwaite Philip W Inhaler
US5296234A (en) * 1991-10-11 1994-03-22 Abbott Laboratories Holder and packaging for a hardened medicated matrix
US5348158A (en) * 1991-12-19 1994-09-20 G. D. Searle & Co. Dispenser pack for the successive dispensing of a drug
US5507277A (en) * 1993-01-29 1996-04-16 Aradigm Corporation Lockout device for controlled release of drug from patient-activateddispenser
US5694919A (en) 1993-01-29 1997-12-09 Aradigm Corporation Lockout device for controlled release of drug from patient-activated dispenser
US5724957A (en) 1993-01-29 1998-03-10 Aradigm Corporation Intrapulmonary delivery of narcotics
US6685013B2 (en) 1994-07-13 2004-02-03 Centrix, Inc. Single patient dose medicament dispenser with applicator
ATE228024T1 (de) * 1994-09-16 2002-12-15 Glaxosmithkline Lab Sas Inhalator
US6425892B2 (en) 1995-06-05 2002-07-30 Alza Corporation Device for transdermal electrotransport delivery of fentanyl and sufentanil
US6881208B1 (en) 1995-06-05 2005-04-19 Joseph B. Phipps Method and device for transdermal electrotransport delivery of fentanyl and sufentanil
BR9609358A (pt) 1995-06-05 1999-05-18 Alza Corp Dispositivo para distribuição transdérmica por eletrotransporte fentanil e sufentanil
US6216033B1 (en) 1996-05-22 2001-04-10 Alza Corporation Device for transdermal electrotransport delivery of fentanyl and sufentanil
DE69637920D1 (de) 1995-06-07 2009-06-18 Oneil Alexander G B Vom Patienten gesteuerte Vorrichtung zur Arzneimittelabgabe
US5710551A (en) 1995-07-26 1998-01-20 Ridgeway; Donald G. Self-medication monitoring system
CA2184316A1 (en) 1995-09-12 1997-03-13 Wei-Chi Liao Buccal delivery system for therapeutic agents
AUPN603895A0 (en) * 1995-10-19 1995-11-09 University Of Queensland, The Production of analgesic synergy by co-administration of sub-analgesic doses of two strong opioids
GB2309966A (en) 1996-02-07 1997-08-13 Harwill Ind Pty Ltd Teat device for administering medicaments
US5995938A (en) 1996-02-27 1999-11-30 Whaley; Susan S. Medication compliance system
NL1003596C2 (nl) 1996-07-15 1997-05-27 Cons Health Entrepreneurs Bv Geneesmiddelafgifte-automaat.
US6248789B1 (en) 1996-08-29 2001-06-19 Stuart L. Weg Administration of ketamine to manage pain and to reduce drug dependency
US5800832A (en) * 1996-10-18 1998-09-01 Virotex Corporation Bioerodable film for delivery of pharmaceutical compounds to mucosal surfaces
US5954641A (en) 1997-09-08 1999-09-21 Informedix, Inc. Method, apparatus and operating system for managing the administration of medication and medical treatment regimens
US5752620A (en) 1996-11-13 1998-05-19 Pearson Ventures, L.L.C. Medication dispenser
US5968547A (en) * 1997-02-24 1999-10-19 Euro-Celtique, S.A. Method of providing sustained analgesia with buprenorphine
US5950632A (en) 1997-03-03 1999-09-14 Motorola, Inc. Medical communication apparatus, system, and method
US6024981A (en) * 1997-04-16 2000-02-15 Cima Labs Inc. Rapidly dissolving robust dosage form
US5945651A (en) 1997-07-17 1999-08-31 Chorosinski; Leonard Remotely programmable medication dispensing system
US5850937A (en) 1997-08-14 1998-12-22 Rauche; Stephen J. Dispenser with means for alerting a user
US20030185761A1 (en) * 1997-10-01 2003-10-02 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating pain
AU759018B2 (en) * 1997-10-03 2003-04-03 Warner-Lambert Company Compressed nitroglycerin tablet and its method of manufacture
US5997518A (en) * 1998-01-14 1999-12-07 Laibovitz; Robert A. Apparatus and method for delivery of small volumes of liquid
US5981552A (en) 1998-10-23 1999-11-09 Taylor Pharmaceuticals Sublingual and buccal compositions of droperidol and method for treating migraine
US6350470B1 (en) * 1998-04-29 2002-02-26 Cima Labs Inc. Effervescent drug delivery system for oral administration
US6576250B1 (en) 1998-03-27 2003-06-10 Cima Labs Inc. Pharmaceutical compositions for rectal and vaginal administration
US6200604B1 (en) * 1998-03-27 2001-03-13 Cima Labs Inc. Sublingual buccal effervescent
US6974590B2 (en) * 1998-03-27 2005-12-13 Cima Labs Inc. Sublingual buccal effervescent
US20030091629A1 (en) * 1998-03-27 2003-05-15 Cima Labs Inc. Sublingual buccal effervescent
US6039251A (en) 1998-04-16 2000-03-21 Holowko; Paul L. Method and system for secure control of a medical device
SE9803239D0 (sv) * 1998-09-24 1998-09-24 Diabact Ab Composition for the treatment of acute pain
SE9803240D0 (sv) * 1998-09-24 1998-09-24 Diabact Ab A pharmaceutical composition having a rapid action
GB9826192D0 (en) * 1998-12-01 1999-01-20 Controlled Theraputics Scotlan Oral transmucosal delivery
AU2879100A (en) * 1999-02-12 2000-08-29 Miles A. Libbey Iii Formulation and system for intra-oral delivery of pharmaceutical agents
US6680071B1 (en) * 1999-03-03 2004-01-20 R. P. Scherer Technologies, Inc. Opioid agonist in a fast dispersing dosage form
US6541021B1 (en) 1999-03-18 2003-04-01 Durect Corporation Devices and methods for pain management
US6835194B2 (en) 1999-03-18 2004-12-28 Durect Corporation Implantable devices and methods for treatment of pain by delivery of fentanyl and fentanyl congeners
US6234343B1 (en) 1999-03-26 2001-05-22 Papp Enterprises, Llc Automated portable medication radial dispensing apparatus and method
US6601729B1 (en) 1999-03-26 2003-08-05 Papp Enterprises, Llc Automated portable medication radial dispensing apparatus and method using a carrier tape
US6210699B1 (en) * 1999-04-01 2001-04-03 Watson Pharmaceuticals, Inc. Oral transmucosal delivery of drugs or any other ingredients via the inner buccal cavity
US6762684B1 (en) 1999-04-19 2004-07-13 Accutrak Systems, Inc. Monitoring system
US6319510B1 (en) * 1999-04-20 2001-11-20 Alayne Yates Gum pad for delivery of medication to mucosal tissues
US6190326B1 (en) 1999-04-23 2001-02-20 Medtrac Technologies, Inc. Method and apparatus for obtaining patient respiratory data
GB9911388D0 (en) 1999-05-18 1999-07-14 Glaxo Group Ltd Dispenser
US6395300B1 (en) * 1999-05-27 2002-05-28 Acusphere, Inc. Porous drug matrices and methods of manufacture thereof
US7919119B2 (en) * 1999-05-27 2011-04-05 Acusphere, Inc. Porous drug matrices and methods of manufacture thereof
WO2001012174A1 (en) 1999-08-13 2001-02-22 Vela Pharmaceuticals Inc. Cyclobenzaprine for treating generalized anxiety disorder and compositions thereof
US6264983B1 (en) * 1999-09-16 2001-07-24 Rhodia, Inc. Directly compressible, ultra fine acetaminophen compositions and process for producing same
FR2799124B1 (fr) 1999-10-01 2004-08-13 Sanofi Synthelabo Utilisation des antagonistes des recepteurs aux cannabinoides centraux pour la preparation de medicaments
US6382204B1 (en) 1999-10-14 2002-05-07 Becton Dickinson And Company Drug delivery system including holder and drug container
US6264981B1 (en) * 1999-10-27 2001-07-24 Anesta Corporation Oral transmucosal drug dosage using solid solution
AU2427201A (en) * 1999-12-06 2001-06-12 Mallinckrodt, Inc. New methods for the syntheses of alfentanil, sufentanil and remifentanil
CO5270018A1 (es) * 1999-12-11 2003-04-30 Glaxo Group Ltd Distribuidor de medicamento
AT408488B (de) 1999-12-22 2001-12-27 Scan Messtechnik Gmbh Miniaturisiertes spektrometer
US6294999B1 (en) * 1999-12-29 2001-09-25 Becton, Dickinson And Company Systems and methods for monitoring patient compliance with medication regimens
US6471645B1 (en) 1999-12-30 2002-10-29 Medtronic, Inc. Communications system for an implantable device and a drug dispenser
HUP0300491A2 (en) 2000-02-28 2003-07-28 Vectura Ltd Improvements in or relating to the delivery of oral drugs
WO2002011778A1 (en) * 2000-05-10 2002-02-14 University Of Kentucky Research Foundation System and method for intranasal administration of opioids
DE10025946A1 (de) * 2000-05-26 2001-11-29 Gruenenthal Gmbh Wirkstoffkombination
AT409366B (de) * 2000-06-20 2002-07-25 Haas Beteiligungsgesellschaft Magazin zur aufnahme und vereinzelten abgabe von tabletten
AU2001274307A1 (en) * 2000-06-22 2002-01-02 Pharmasol Ltd Pharmaceutical compositions
DE20122843U1 (de) * 2000-07-31 2008-06-26 Nycomed Danmark Aps Fentanyl Zusammensetzung zur nasalen Anwendung
NZ524124A (en) * 2000-08-18 2004-09-24 Pharmacia Corp Rapidly disintegrating oral formulation of a cyclooxygenase-2 inhibitor
US20020026330A1 (en) 2000-08-23 2002-02-28 Klein Edward E. System and method for patient medication management and compliance using a portable computing device
US6417184B1 (en) 2000-09-19 2002-07-09 David M. Ockert Triple drug therapy for the treatment and prevention of acute or chronic pain
US20050054942A1 (en) * 2002-01-22 2005-03-10 Melker Richard J. System and method for therapeutic drug monitoring
US20020160043A1 (en) * 2001-02-27 2002-10-31 Dennis Coleman Compositions and method of manufacture for oral dissolvable dosage forms
US20050176790A1 (en) * 2001-02-28 2005-08-11 Johannes Bartholomaus Pharmaceutical salts
JP4850346B2 (ja) * 2001-03-15 2012-01-11 救急薬品工業株式会社 粘膜貼付剤
GB0108228D0 (en) 2001-04-02 2001-05-23 Glaxo Group Ltd Medicament dispenser
GB0108215D0 (en) 2001-04-02 2001-05-23 Glaxo Group Ltd Medicament dispenser
US7125561B2 (en) 2001-05-22 2006-10-24 Euro-Celtique S.A. Compartmentalized dosage form
NZ529417A (en) 2001-05-24 2006-11-30 Alexza Pharmaceuticals Inc Delivery of alprazolam, estazolam, midazolam or triazolam through an inhalation route
US7090830B2 (en) * 2001-05-24 2006-08-15 Alexza Pharmaceuticals, Inc. Drug condensation aerosols and kits
US7458374B2 (en) * 2002-05-13 2008-12-02 Alexza Pharmaceuticals, Inc. Method and apparatus for vaporizing a compound
JP2005503425A (ja) 2001-05-24 2005-02-03 アレックザ モレキュラー デリヴァリー コーポレイション 所定の吸入ルートによる薬剤エステルの送出
US20030051728A1 (en) * 2001-06-05 2003-03-20 Lloyd Peter M. Method and device for delivering a physiologically active compound
US6685951B2 (en) * 2001-07-05 2004-02-03 R. T. Alamo Ventures I, Inc. Administration of dihydroergotamine as a sublingual spray or aerosol for the treatment of migraine
US20030008005A1 (en) 2001-07-05 2003-01-09 R.T. Alamo Ventures, Inc. Sublingual administration of dihydroergotamine for the treatment of migraine
US20030022910A1 (en) * 2001-07-05 2003-01-30 R.T. Alamo Ventures I, Inc. Compositions and methods for sublingual formulations of dihydroergotamine for the treatment of migraine
US20030017175A1 (en) 2001-07-05 2003-01-23 R.T. Alamo Ventures I, Inc. Sublingual administration of dihydroergotamine for the treatment of migraine
US20030068356A1 (en) 2001-07-10 2003-04-10 Pather S. Indiran Sequential drug delivery systems
AU2002321885A1 (en) 2001-08-03 2003-02-24 Hill-Rom Services, Inc. Patient point-of-care computer system
US7743923B2 (en) 2001-09-19 2010-06-29 Avanced MOD Corporation Patient controlled timed medication dispenser
US7044302B2 (en) * 2001-09-19 2006-05-16 Avancen, Inc. Patient controlled timed oral medication dispenser
JP2005506885A (ja) 2001-10-22 2005-03-10 スリーエム イノベイティブ プロパティズ カンパニー 経皮/経粘膜パッチ包装
US20030130314A1 (en) * 2001-12-17 2003-07-10 Pascal Druzgala Analgesic delivery systems and methods of use
EP1478420B1 (en) 2002-02-22 2009-09-09 G W Pharma Limited Dose dispensing system and apparatus
US7074426B2 (en) * 2002-03-27 2006-07-11 Frank Kochinke Methods and drug delivery systems for the treatment of orofacial diseases
GB0209783D0 (en) 2002-04-29 2002-06-05 Glaxo Group Ltd Medicament dispenser
US6961541B2 (en) 2002-05-24 2005-11-01 Aeroscout, Inc. Method and apparatus for enhancing security in a wireless network using distance measurement techniques
US6793075B1 (en) 2002-05-30 2004-09-21 Michael Jeter Container for dispensing a liquid and method of using the same
DE10226494A1 (de) 2002-06-14 2004-01-08 Lts Lohmann Therapie-Systeme Ag Filmförmige mucoadhäsive Darreichungsformen zur Verabreichung von Cannabis-Wirkstoffen
ATE424010T1 (de) * 2002-06-21 2009-03-15 Glaxo Group Ltd Betätigungsanzeiger für eine abgabevorrichtung
WO2004014567A1 (en) * 2002-08-06 2004-02-19 Glaxo Group Limited A dispenser
US9486581B2 (en) 2002-09-11 2016-11-08 Becton, Dickinson And Company Injector device with force lock-out and injection rate limiting mechanisms
US7295890B2 (en) * 2002-09-26 2007-11-13 Stratamed Labs, Inc. Prescription drug compliance monitoring system
US6963289B2 (en) 2002-10-18 2005-11-08 Aeroscout, Ltd. Wireless local area network (WLAN) channel radio-frequency identification (RFID) tag system and method therefor
US6999092B2 (en) 2002-10-25 2006-02-14 Fujitsu Limited Image display apparatus in which a specific area display attribute is modifiable
GB0226022D0 (en) * 2002-11-07 2002-12-18 Corporate Intellectual Propert Device
NZ540282A (en) 2002-11-18 2008-06-30 Yaupon Therapeutics Inc Analgesic uses of norketamine and ketamine/norketamine prodrugs
ES2270335T7 (es) * 2003-01-31 2012-03-16 Orexo Ab Composicion farmaceuta de efecto.
US20040253307A1 (en) 2003-02-04 2004-12-16 Brian Hague Sugar-free oral transmucosal solid dosage forms and uses thereof
KR20120066688A (ko) 2003-02-24 2012-06-22 파마슈티칼 프로덕션스, 인크. 경점막 약물 전달 시스템
US20060062812A1 (en) * 2003-03-11 2006-03-23 Calvin Ross Novel compositions
GB0305581D0 (en) 2003-03-11 2003-04-16 Dallas Burston Ltd Dispensing devices
CA2522471A1 (en) * 2003-04-14 2004-10-28 Pain Therapeutics, Inc. Methods for the treatment of pain comprising opioid antagonists
US7276246B2 (en) 2003-05-09 2007-10-02 Cephalon, Inc. Dissolvable backing layer for use with a transmucosal delivery device
US7306812B2 (en) 2003-05-09 2007-12-11 Cephalon, Inc. Dissolvable backing layer for use with a transmucosal delivery device
US6914668B2 (en) 2003-05-14 2005-07-05 International Technologies (Laser) Ltd. Personal identification verification and controlled substance detection and identification system
BR0302017B1 (pt) * 2003-06-02 2014-10-29 Ems Sigma Pharma Ltda Composição farmacêutica sublingual a base de um agonista do receptor central de benzodiazepínicos
US20050049464A1 (en) 2003-08-29 2005-03-03 Lassers Harold Aaron Remote pharmaceutical administration device
US7248165B2 (en) 2003-09-09 2007-07-24 Motorola, Inc. Method and apparatus for multiple frequency RFID tag architecture
US20050065175A1 (en) * 2003-09-24 2005-03-24 Xanodyne Pharmacal, Inc. Oral transmucosal methadone
US8157788B2 (en) 2003-11-06 2012-04-17 Paolo L. Manfredi Multi-site drug delivery platform
US6999028B2 (en) 2003-12-23 2006-02-14 3M Innovative Properties Company Ultra high frequency radio frequency identification tag
PT1708686E (pt) * 2003-12-31 2011-04-20 Cima Labs Inc Forma de dosagem de fentanil oral efervescente geralmente linear e métodos de administração
US20070036853A1 (en) * 2003-12-31 2007-02-15 Cima Labs Inc. Generally linear effervescent oral fentanyl dosage form and methods of administering
WO2005065317A2 (en) * 2003-12-31 2005-07-21 Cima Labs Inc. Effervescent oral fentanyl dosage form
EP1708685B1 (en) * 2003-12-31 2011-03-09 Cima Labs Inc. Effervescent oral opiate dosage forms and methods of administering oxycodone
US20060026035A1 (en) 2004-07-28 2006-02-02 William Younkes Computer aided interactive medical management information and control system and method
US20060045865A1 (en) * 2004-08-27 2006-03-02 Spherics, Inc. Controlled regional oral delivery
US20060067978A1 (en) * 2004-09-29 2006-03-30 Bausch & Lomb Incorporated Process for preparing poly(vinyl alcohol) drug delivery devices
US7388493B2 (en) 2004-10-08 2008-06-17 Bartronics America, Inc. Method and system for preventing unauthorized removal and use of an RFID apparatus
US7119690B2 (en) 2004-10-08 2006-10-10 Proximities, Inc. Identification band using serpentine paths to detect tampering
US20060089858A1 (en) 2004-10-25 2006-04-27 Tun Ling Means and method of applying RFID and PKI technologies for patient safety
FR2883179B1 (fr) * 2005-03-18 2009-04-17 Ethypharm Sa Comprime enrobe
US20070020186A1 (en) * 2005-07-22 2007-01-25 Alpex Pharma S.A. Solid dosage formulations of narcotic drugs having improved buccal adsorption
WO2007035913A2 (en) 2005-09-21 2007-03-29 Kurve Technology, Inc. Medicament delivery control, monitoring, and reporting system and method
US20070104763A1 (en) 2005-11-10 2007-05-10 Navinta Llc Composition of fentanyl citrate oral solid transmucosal dosage form, excipient and binding material therefore, and methods of making
US8202535B2 (en) * 2006-01-06 2012-06-19 Acelrx Pharmaceuticals, Inc. Small-volume oral transmucosal dosage forms
US8865743B2 (en) 2006-01-06 2014-10-21 Acelrx Pharmaceuticals, Inc. Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
WO2007084290A2 (en) 2006-01-12 2007-07-26 Orexigen Therapeutics, Inc. Compositions of an anticonvulsant and psychotherapeutic and methods of using the same for reversing weight gain
US20070190130A1 (en) 2006-02-16 2007-08-16 Mark William A Protein hydrolysate excipients
US20070286900A1 (en) 2006-06-09 2007-12-13 Catherine Herry Low dose tablets of opioid analgesics and preparation process

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