JP2009531456A - （ｒ）−３−アミノピペリジン二塩酸塩の調製 - Google Patents

（ｒ）−３−アミノピペリジン二塩酸塩の調製 Download PDF

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Publication number
JP2009531456A
JP2009531456A JP2009503202A JP2009503202A JP2009531456A JP 2009531456 A JP2009531456 A JP 2009531456A JP 2009503202 A JP2009503202 A JP 2009503202A JP 2009503202 A JP2009503202 A JP 2009503202A JP 2009531456 A JP2009531456 A JP 2009531456A
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alkyl
group
cycloalkyl
aryl
hetero
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JP2009503202A
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Japanese (ja)
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JP2009531456A5 (enExample
Inventor
ビー． ウォレス、マイケル
コーディー、ジェレミー
フォルニコラ、リチャード
ガルシア−ルビオ、シルヴィーナ
ビー． キサンガ、フィリップ
エム． リーヴ、マクスウェル
ウィルソン、チャンドラ
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Takeda Pharmaceutical Co Ltd
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Takeda Pharmaceutical Co Ltd
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Application filed by Takeda Pharmaceutical Co Ltd filed Critical Takeda Pharmaceutical Co Ltd
Publication of JP2009531456A publication Critical patent/JP2009531456A/ja
Publication of JP2009531456A5 publication Critical patent/JP2009531456A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2009503202A 2006-03-28 2007-03-26 （ｒ）−３−アミノピペリジン二塩酸塩の調製 Pending JP2009531456A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78705806P 2006-03-28 2006-03-28
PCT/US2007/064958 WO2007112368A1 (en) 2006-03-28 2007-03-26 Preparation of (r)-3-aminopiperidine dihydrochloride

Publications (2)

Publication Number Publication Date
JP2009531456A true JP2009531456A (ja) 2009-09-03
JP2009531456A5 JP2009531456A5 (enExample) 2010-05-13

Family

ID=38353397

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009503202A Pending JP2009531456A (ja) 2006-03-28 2007-03-26 （ｒ）−３−アミノピペリジン二塩酸塩の調製

Country Status (4)

Country Link
US (1) US20100029941A1 (enExample)
EP (1) EP1999108A1 (enExample)
JP (1) JP2009531456A (enExample)
WO (1) WO2007112368A1 (enExample)

Cited By (3)

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JP2010511063A (ja) * 2006-11-29 2010-04-08 武田薬品工業株式会社 ２−［６−（３−アミノ−ピペリジン−１−イル）−３−メチル−２，４−ジオキソ−３，４−ジヒドロ−２ｈ−ピリミジン−１−イルメチル］−４−フルオロ−ベンゾニトリルのコハク酸塩の多形及びこれらの使用方法
JP2018168194A (ja) * 2013-02-20 2018-11-01 ロイター ヒェミッシャー アパラーテバウ コマンディートゲゼルシャフトＲｅｕｔｅｒ Ｃｈｅｍｉｓｃｈｅｒ Ａｐｐａｒａｔｅｂａｕ ＫＧ エナンチオマー濃縮された３−アミノピペリジンの調製のためのプロセス
JPWO2022138987A1 (enExample) * 2021-04-14 2022-06-30

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UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
MY164581A (en) 2008-08-15 2018-01-15 Boehringer Ingelheim Int Purin derivatives for use in the treatment of fab-related diseases
TW201036975A (en) 2009-01-07 2010-10-16 Boehringer Ingelheim Int Treatment for diabetes in patients with inadequate glycemic control despite metformin therapy
TWI466672B (zh) 2009-01-29 2015-01-01 Boehringer Ingelheim Int 小兒科病人糖尿病之治療
EP2395983B1 (en) 2009-02-13 2020-04-08 Boehringer Ingelheim International GmbH Pharmaceutical composition comprisng a sglt2 inhibitor, a dpp-iv inhibitor and optionally a further antidiabetic agent and uses thereof
EA029759B1 (ru) 2009-02-13 2018-05-31 Бёрингер Ингельхайм Интернациональ Гмбх Антидиабетические лекарственные средства, содержащие ингибитор dpp-4 (линаглиптин) необязательно в комбинации с другими антидиабетическими средствами
EP3646859A1 (en) 2009-11-27 2020-05-06 Boehringer Ingelheim International GmbH Treatment of genotyped diabetic patients with dpp-iv inhibitors such as linagliptin
WO2011079778A1 (en) 2009-12-30 2011-07-07 China Shanghai Fochon Pharmaceutical Co Ltd 3-(3-aminopiperidin-1-yl)-5-oxo-1,2,4-triazine derivates as dipeptidyl peptidase iv(dpp-iv) inhibitors
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CN103274993A (zh) * 2013-06-13 2013-09-04 南京工业大学 二氢吡啶和吡咯类杂环的新合成方法
JO3517B1 (ar) 2014-01-17 2020-07-05 Novartis Ag ان-ازاسبيرو الكان حلقي كبديل مركبات اريل-ان مغايرة وتركيبات لتثبيط نشاط shp2
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JP6878316B2 (ja) * 2015-06-19 2021-05-26 ノバルティス アーゲー Ｓｈｐ２の活性を阻害するための化合物および組成物
WO2017076349A1 (zh) * 2015-11-05 2017-05-11 四川科伦博泰生物医药股份有限公司 长效二肽基肽酶-iv抑制剂、其用途及其制备方法
WO2017216706A1 (en) 2016-06-14 2017-12-21 Novartis Ag Compounds and compositions for inhibiting the activity of shp2
RU2769132C2 (ru) 2017-01-10 2022-03-28 Новартис Аг Фармацевтическая комбинация, содержащая ингибитор alk и ингибитор shp2
CN108017614A (zh) * 2018-01-25 2018-05-11 中国科学院海洋研究所 Dpp-4抑制剂及其在制备治疗2型糖尿病药物中的应用
US12047248B2 (en) 2020-10-26 2024-07-23 Samsung Electronics Co., Ltd. Method of controlling state control parameter for adjusting state of network of base station by using any one of plurality of models and electronic device performing the method
TR202022144A1 (tr) 2020-12-29 2022-07-21 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Alogli̇pti̇n i̇çeren farmasöti̇k kompozi̇syonlar
TR202022612A2 (tr) 2020-12-31 2022-07-21 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Alogli̇pti̇ni̇n farmasöti̇k kapsül kompozi̇syonlari
CN116482280A (zh) * 2023-05-22 2023-07-25 北京北陆益康医药研发有限公司 一种测定氨基哌啶双盐酸盐异构体的方法

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JP2018168194A (ja) * 2013-02-20 2018-11-01 ロイター ヒェミッシャー アパラーテバウ コマンディートゲゼルシャフトＲｅｕｔｅｒ Ｃｈｅｍｉｓｃｈｅｒ Ａｐｐａｒａｔｅｂａｕ ＫＧ エナンチオマー濃縮された３−アミノピペリジンの調製のためのプロセス
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WO2022138987A1 (ja) * 2021-04-14 2022-06-30 塩野義製薬株式会社 ウイルス増殖阻害作用を有するトリアジン誘導体およびそれらを含有する医薬組成物
JP7530596B2 (ja) 2021-04-14 2024-08-08 塩野義製薬株式会社 ウイルス増殖阻害作用を有するトリアジン誘導体およびそれらを含有する医薬組成物
JP2024153693A (ja) * 2021-04-14 2024-10-29 塩野義製薬株式会社 ウイルス増殖阻害作用を有するトリアジン誘導体およびそれらを含有する医薬組成物
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