JP2009529497A5 - - Google Patents

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Publication number
JP2009529497A5
JP2009529497A5 JP2008556619A JP2008556619A JP2009529497A5 JP 2009529497 A5 JP2009529497 A5 JP 2009529497A5 JP 2008556619 A JP2008556619 A JP 2008556619A JP 2008556619 A JP2008556619 A JP 2008556619A JP 2009529497 A5 JP2009529497 A5 JP 2009529497A5
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JP
Japan
Prior art keywords
monoclonal antibody
ligand
pharmaceutical composition
human
antibody
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Application number
JP2008556619A
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English (en)
Japanese (ja)
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JP2009529497A (ja
JP5247474B2 (ja
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Publication date
Priority claimed from US11/364,013 external-priority patent/US7947496B2/en
Application filed filed Critical
Publication of JP2009529497A publication Critical patent/JP2009529497A/ja
Publication of JP2009529497A5 publication Critical patent/JP2009529497A5/ja
Application granted granted Critical
Publication of JP5247474B2 publication Critical patent/JP5247474B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2008556619A 2006-02-28 2007-02-23 Ｃｄ４４の表面発現を証明する細胞の細胞障害性媒介 Expired - Fee Related JP5247474B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/364,013 US7947496B2 (en) 1999-10-08 2006-02-28 Cytotoxicity mediation of cells evidencing surface expression of CD44
US11/364,013 2006-02-28
PCT/CA2007/000281 WO2007098575A1 (en) 2006-02-28 2007-02-23 Cytotoxicity mediation of cells evidencing surface expression of cd44

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013029374A Division JP2013165710A (ja) 2006-02-28 2013-02-18 Ｃｄ４４の表面発現を証明する細胞の細胞障害性媒介

Publications (3)

Publication Number Publication Date
JP2009529497A JP2009529497A (ja) 2009-08-20
JP2009529497A5 true JP2009529497A5 (enExample) 2012-07-12
JP5247474B2 JP5247474B2 (ja) 2013-07-24

Family

ID=38458603

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2008556619A Expired - Fee Related JP5247474B2 (ja) 2006-02-28 2007-02-23 Ｃｄ４４の表面発現を証明する細胞の細胞障害性媒介
JP2013029374A Pending JP2013165710A (ja) 2006-02-28 2013-02-18 Ｃｄ４４の表面発現を証明する細胞の細胞障害性媒介

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2013029374A Pending JP2013165710A (ja) 2006-02-28 2013-02-18 Ｃｄ４４の表面発現を証明する細胞の細胞障害性媒介

Country Status (15)

Country Link
US (3) US7947496B2 (enExample)
EP (2) EP1989233B1 (enExample)
JP (2) JP5247474B2 (enExample)
CN (2) CN103197067A (enExample)
AU (1) AU2007219656B2 (enExample)
CA (1) CA2643708A1 (enExample)
CY (1) CY1115212T1 (enExample)
DK (1) DK1989233T3 (enExample)
ES (1) ES2444408T3 (enExample)
NZ (1) NZ570776A (enExample)
PL (1) PL1989233T3 (enExample)
PT (1) PT1989233E (enExample)
SI (1) SI1989233T1 (enExample)
TW (1) TW200731987A (enExample)
WO (1) WO2007098575A1 (enExample)

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US8071072B2 (en) * 1999-10-08 2011-12-06 Hoffmann-La Roche Inc. Cytotoxicity mediation of cells evidencing surface expression of CD44
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US20090004103A1 (en) * 1999-10-08 2009-01-01 Young David S F Cytotoxicity mediation of cells evidencing surface expression of CD44
CN101663049A (zh) * 2007-03-09 2010-03-03 霍夫曼-拉罗奇有限公司 证明cd44表面表达的细胞的细胞毒性介导
EP2009028A1 (en) * 2007-06-27 2008-12-31 Monoclonal Antibodies Therapeutics Combination of a conventional anti-cancer treatment with anti-CD44 antibody administration for treating solid tumors
EP2547693B1 (en) 2010-03-19 2015-03-11 H. Lee Moffitt Cancer Center & Research Institute Integrin interaction inhibitors for the treatment of cancer
WO2012129335A2 (en) * 2011-03-21 2012-09-27 H. Lee Moffitt Cancer Center And Research Institute, Inc Hyd1 peptides for relapsed cancer
JP6077997B2 (ja) 2011-09-07 2017-02-08 中外製薬株式会社 癌幹細胞の分離
WO2015048477A1 (en) 2013-09-27 2015-04-02 H. Lee Moffitt Cancer Center And Research Institute, Inc. Cyclic peptide conjugates and methods of use
CN109402064B (zh) * 2018-11-05 2021-05-14 湖南省肿瘤医院 杂交瘤细胞株及其产生的单克隆抗体和应用
CN112569351B (zh) * 2020-12-16 2021-10-15 南通大学 Cd44抗体在制备治疗帕金森疾病的药物中的应用
CN114250200A (zh) * 2021-12-23 2022-03-29 蚌埠医学院 一种非小细胞肺癌脑转移和脊髓转移的动物模型构建方法

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