JP2023510429A5 - - Google Patents

Info

Publication number
JP2023510429A5
JP2023510429A5 JP2022566507A JP2022566507A JP2023510429A5 JP 2023510429 A5 JP2023510429 A5 JP 2023510429A5 JP 2022566507 A JP2022566507 A JP 2022566507A JP 2022566507 A JP2022566507 A JP 2022566507A JP 2023510429 A5 JP2023510429 A5 JP 2023510429A5
Authority
JP
Japan
Prior art keywords
sequence
seq
antigen
hcvr
lcvr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022566507A
Other languages
English (en)
Japanese (ja)
Other versions
JP7719799B2 (ja
JP2023510429A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2021/070473 external-priority patent/WO2021139682A1/en
Publication of JP2023510429A publication Critical patent/JP2023510429A/ja
Publication of JP2023510429A5 publication Critical patent/JP2023510429A5/ja
Application granted granted Critical
Publication of JP7719799B2 publication Critical patent/JP7719799B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022566507A 2020-01-07 2021-01-06 抗ガレクチン-9抗体およびその使用 Active JP7719799B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062957910P 2020-01-07 2020-01-07
US62/957,910 2020-01-07
PCT/CN2021/070473 WO2021139682A1 (en) 2020-01-07 2021-01-06 Anti-galectin-9 antibody and uses thereof

Publications (3)

Publication Number Publication Date
JP2023510429A JP2023510429A (ja) 2023-03-13
JP2023510429A5 true JP2023510429A5 (enExample) 2024-01-16
JP7719799B2 JP7719799B2 (ja) 2025-08-06

Family

ID=74194447

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022566507A Active JP7719799B2 (ja) 2020-01-07 2021-01-06 抗ガレクチン-9抗体およびその使用

Country Status (11)

Country Link
US (1) US12649794B2 (enExample)
EP (1) EP4087873A1 (enExample)
JP (1) JP7719799B2 (enExample)
KR (1) KR20220123105A (enExample)
CN (2) CN120647763A (enExample)
AU (1) AU2021205143A1 (enExample)
BR (1) BR112022013494A2 (enExample)
CA (1) CA3163988A1 (enExample)
IL (1) IL294466A (enExample)
MX (1) MX2022008421A (enExample)
WO (1) WO2021139682A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3021970B1 (fr) † 2014-06-06 2018-01-26 Universite Sciences Technologies Lille Anticorps dirige contre la galectine 9 et inhibiteur de l'activite suppressive des lymphocytes t regulateurs
AU2021205143A1 (en) 2020-01-07 2022-07-28 Hifibio, Inc. Anti-Galectin-9 antibody and uses thereof
KR20250029919A (ko) * 2022-06-29 2025-03-05 퓨어테크 엘와이티, 아이엔씨. 갈렉틴-9를 억제하는 항체를 사용한 혈액학적 악성종양의 치료
EP4554682A1 (en) 2022-07-15 2025-05-21 Fibrogen, Inc. Modified anti-galectin-9 antibody and uses thereof
WO2025149667A1 (en) 2024-01-12 2025-07-17 Pheon Therapeutics Ltd Antibody drug conjugates and uses thereof
CN120585880B (zh) * 2025-08-07 2025-12-09 四川大学华西医院 一种用于预防和/或治疗前列腺癌的联合用药物,其用途及药物组合物

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US6713610B1 (en) 1990-01-12 2004-03-30 Raju Kucherlapati Human antibodies derived from immunized xenomice
US6673986B1 (en) 1990-01-12 2004-01-06 Abgenix, Inc. Generation of xenogeneic antibodies
US5877397A (en) 1990-08-29 1999-03-02 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
US5874299A (en) 1990-08-29 1999-02-23 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US6300129B1 (en) 1990-08-29 2001-10-09 Genpharm International Transgenic non-human animals for producing heterologous antibodies
US6255458B1 (en) 1990-08-29 2001-07-03 Genpharm International High affinity human antibodies and human antibodies against digoxin
US6342220B1 (en) 1997-08-25 2002-01-29 Genentech, Inc. Agonist antibodies
AU6366999A (en) 1998-10-30 2000-05-22 Takeda Chemical Industries Ltd. Betacellulin protein-containing preparations
US6900292B2 (en) 2001-08-17 2005-05-31 Lee-Hwei K. Sun Fc fusion proteins of human erythropoietin with increased biological activities
KR100976076B1 (ko) 2003-05-22 2010-08-17 아보트 러보러터리즈 인다졸, 벤즈이속사졸 및 벤즈이소티아졸 키나제 억제제
EP1649020B1 (en) 2003-07-21 2017-01-11 MSD Italia S.r.l. Synthetic gene encoding human epidermal growth factor 2/neu antigen and uses thereof
DK1678314T3 (da) 2003-10-22 2012-12-03 Keck Graduate Inst Fremgangsmåde til syntetisering af heteromultimere polypeptider i gær ved anvendelse af en haploid parringsstrategi
TWI309240B (en) 2004-09-17 2009-05-01 Hoffmann La Roche Anti-ox40l antibodies
WO2006076288A2 (en) 2005-01-11 2006-07-20 Five Prime Therapeutics, Inc. Dna constructs for long-term expression of intravascularly injected naked dna
JP5238936B2 (ja) 2005-03-25 2013-07-17 ジーアイティーアール,インク. Gitr結合分子およびその使用
DK1879573T3 (da) 2005-05-10 2013-02-25 Incyte Corp Modulatorer af indolamin 2,3-dioxygenase og fremgangsmåder til anvendelse deraf
KR101704734B1 (ko) 2005-07-01 2017-02-09 이. 알. 스퀴부 앤드 선즈, 엘.엘.씨. 예정 사멸 리간드 1 (피디-엘1)에 대한 인간 모노클로날 항체
ES2540561T3 (es) 2005-12-20 2015-07-10 Incyte Corporation N-hidroxiamidinoheterociclos como moduladores de indolamina 2,3-dioxigenasa
CA2663057C (en) 2006-09-19 2015-12-08 Incyte Corporation N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase
CL2007002650A1 (es) 2006-09-19 2008-02-08 Incyte Corp Compuestos derivados de heterociclo n-hidroxiamino; composicion farmaceutica, util para tratar cancer, infecciones virales y desordenes neurodegenerativos entre otras.
EP1987839A1 (en) 2007-04-30 2008-11-05 I.N.S.E.R.M. Institut National de la Sante et de la Recherche Medicale Cytotoxic anti-LAG-3 monoclonal antibody and its use in the treatment or prevention of organ transplant rejection and autoimmune disease
PT2175884T (pt) 2007-07-12 2016-09-21 Gitr Inc Terapias de combinação empregando moléculas de ligação a gitr
US7981415B2 (en) 2007-09-07 2011-07-19 Cisthera, Inc. Humanized PAI-1 antibodies
EP2044949A1 (en) 2007-10-05 2009-04-08 Immutep Use of recombinant lag-3 or the derivatives thereof for eliciting monocyte immune response
WO2009073620A2 (en) 2007-11-30 2009-06-11 Newlink Genetics Ido inhibitors
US8093018B2 (en) 2008-05-20 2012-01-10 Otsuka Pharmaceutical Co., Ltd. Antibody identifying an antigen-bound antibody and an antigen-unbound antibody, and method for preparing the same
EP2296789A1 (fr) 2008-05-29 2011-03-23 Saint-Gobain Centre de Recherches et d'Etudes Européen Structure en nid d'abeille a base de titanate d'aluminium
AR072999A1 (es) 2008-08-11 2010-10-06 Medarex Inc Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos
MX356367B (es) 2008-12-09 2018-05-25 Genentech Inc Anticuerpos anti-pd-l1 y su uso para mejorar la funcion de celulas t.
IN2015DN02826A (enExample) 2009-09-03 2015-09-11 Merck Sharp & Dohme
EP2493862B1 (en) 2009-10-28 2016-10-05 Newlink Genetics Corporation Imidazole derivatives as ido inhibitors
DK2510010T3 (en) 2009-12-10 2015-12-14 Hoffmann La Roche Antibodies that bind to human CSF1R extracellular domain 4 and their use
DK2542256T3 (da) 2010-03-04 2019-08-26 Macrogenics Inc Antistoffer reagerende med b7-h3, immunologisk aktive fragmenter deraf og anvendelser deraf
CN102918061B (zh) 2010-03-05 2016-06-08 霍夫曼-拉罗奇有限公司 针对人csf-1r的抗体及其用途
RU2617971C2 (ru) 2010-03-05 2017-04-28 Ф.Хоффманн-Ля Рош Аг Антитела против csf-1r человека и их применение
EP3943154A1 (en) 2010-05-04 2022-01-26 Five Prime Therapeutics, Inc. Antibodies that bind csf1r
NZ729044A (en) 2010-09-09 2020-07-31 Pfizer 4-1bb binding molecules
KR20130103587A (ko) * 2010-12-09 2013-09-23 가르파마 컴퍼니 리미티드 갈렉틴 9를 분비하는 세포, 그 제조 방법 및 그 용도
NO2694640T3 (enExample) 2011-04-15 2018-03-17
CA2833636A1 (en) 2011-04-20 2012-10-26 Amplimmune, Inc. Antibodies and other molecules that bind b7-h1 and pd-1
BR112014012819B1 (pt) 2011-11-28 2022-08-16 Merck Patent Gmbh Anticorpo anti-pd-l1 ou fragmento de ligação ao antígeno do mesmo e composição
MX356337B (es) 2011-12-15 2018-05-23 Hoffmann La Roche Anticuerpos contra csf-1r humano y sus usos.
MX2014008961A (es) 2012-02-06 2014-10-14 Genentech Inc Composiciones y metodos para utilizar inhibidores de csf1r.
AR090263A1 (es) 2012-03-08 2014-10-29 Hoffmann La Roche Terapia combinada de anticuerpos contra el csf-1r humano y las utilizaciones de la misma
KR20150018533A (ko) 2012-05-11 2015-02-23 파이브 프라임 테라퓨틱스, 인크. 콜로니 자극 인자 1 수용체(csf1r)에 결속하는 항체들에 의한 질병 상태의 치료 방법
AR091649A1 (es) 2012-07-02 2015-02-18 Bristol Myers Squibb Co Optimizacion de anticuerpos que se fijan al gen de activacion de linfocitos 3 (lag-3) y sus usos
CN107759690A (zh) 2012-08-31 2018-03-06 戊瑞治疗有限公司 用结合群落刺激因子1受体(csf1r)的抗体治疗病状的方法
TW201605896A (zh) 2013-08-30 2016-02-16 安美基股份有限公司 Gitr抗原結合蛋白
FR3021970B1 (fr) 2014-06-06 2018-01-26 Universite Sciences Technologies Lille Anticorps dirige contre la galectine 9 et inhibiteur de l'activite suppressive des lymphocytes t regulateurs
WO2019084553A1 (en) 2017-10-27 2019-05-02 New York University ANTI-GALECTIN-9 ANTIBODIES AND USES THEREOF
CN112166126A (zh) 2018-04-13 2021-01-01 阿根思公司 半乳糖凝集素-10抗体
US11912772B2 (en) 2018-07-16 2024-02-27 University Of Hawaii Anti-galectin-9 antibody and methods of use thereof
CA3134942A1 (en) 2019-03-25 2020-10-01 New York University Anti-galectin-9 antibodies and uses thereof
CN119033928A (zh) 2019-05-01 2024-11-29 纽约大学 抗半乳糖凝集素-9抗体及其用途
AU2021205143A1 (en) 2020-01-07 2022-07-28 Hifibio, Inc. Anti-Galectin-9 antibody and uses thereof
EP4554682A1 (en) 2022-07-15 2025-05-21 Fibrogen, Inc. Modified anti-galectin-9 antibody and uses thereof

Similar Documents

Publication Publication Date Title
RU2492185C2 (ru) Связывающие протеины, специфичные по отношению к инсулин-подобным факторам роста, и их использование
JP5463036B2 (ja) 可溶性ceaに対する抵抗性を有する医薬抗体組成物
JP2013227339A5 (enExample)
JP2013502913A5 (enExample)
JP2019532619A5 (enExample)
RU2015142815A (ru) Лечение рака с использованием антител, связывающихся с поверхностным grp78
KR20160024391A (ko) 종양 성장 및 전이를 억제하기 위한 면역 조절 요법과 병용되는 세마포린-4d 억제성 분자의 용도
JP2022533538A5 (enExample)
WO2014012007A4 (en) Rspo3 binding agents and uses thereof
JP2021528047A5 (enExample)
JP2021510736A5 (enExample)
CN107660151A (zh) 抗‑cd19抗体和布鲁顿酪氨酸激酶抑制剂的组合及其用途
JP2014524902A5 (enExample)
EP3189078B1 (en) Anti-ck8 antibodies for use in the treatment of cancers
JP2021534735A5 (enExample)
JP2023517794A5 (enExample)
JP2024532886A5 (enExample)
EP3092252A1 (en) ANTIBODY TARGETING CELL SURFACE DEPOSITED COMPLEMENT PROTEIN C3d AND USE THEREOF
JP2023510429A (ja) 抗ガレクチン-9抗体およびその使用
JP2023517754A5 (enExample)
JP2024527576A5 (enExample)
JP2021530428A (ja) 頭頸部癌の処置
JP2025510642A5 (enExample)
JP2025148452A5 (enExample)
JP2020531003A5 (enExample)