JP2009529059A5 - - Google Patents

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Publication number
JP2009529059A5
JP2009529059A5 JP2008558416A JP2008558416A JP2009529059A5 JP 2009529059 A5 JP2009529059 A5 JP 2009529059A5 JP 2008558416 A JP2008558416 A JP 2008558416A JP 2008558416 A JP2008558416 A JP 2008558416A JP 2009529059 A5 JP2009529059 A5 JP 2009529059A5
Authority
JP
Japan
Prior art keywords
phenyl
thiazol
trifluoromethyl
pyridin
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2008558416A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009529059A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2007/006023 external-priority patent/WO2007103550A2/en
Publication of JP2009529059A publication Critical patent/JP2009529059A/ja
Publication of JP2009529059A5 publication Critical patent/JP2009529059A5/ja
Withdrawn legal-status Critical Current

Links

JP2008558416A 2006-03-08 2007-03-08 抗c型肝炎ウイルス活性を有する置換アミノチアゾール誘導体 Withdrawn JP2009529059A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78060906P 2006-03-08 2006-03-08
PCT/US2007/006023 WO2007103550A2 (en) 2006-03-08 2007-03-08 Substituted aminothiazole derivatives with anti-hcv activity

Publications (2)

Publication Number Publication Date
JP2009529059A JP2009529059A (ja) 2009-08-13
JP2009529059A5 true JP2009529059A5 (enExample) 2010-03-11

Family

ID=38328551

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008558416A Withdrawn JP2009529059A (ja) 2006-03-08 2007-03-08 抗c型肝炎ウイルス活性を有する置換アミノチアゾール誘導体

Country Status (7)

Country Link
US (1) US20070213301A1 (enExample)
EP (2) EP2460800A1 (enExample)
JP (1) JP2009529059A (enExample)
AU (1) AU2007223797A1 (enExample)
CA (1) CA2645072A1 (enExample)
NZ (1) NZ570835A (enExample)
WO (1) WO2007103550A2 (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20080019213A (ko) * 2005-05-09 2008-03-03 아칠리온 파르마세우티칼스 인코포레이티드 티아졸 화합물 및 그 사용방법
TW200808788A (en) 2006-04-19 2008-02-16 Astellas Pharma Inc Azolecarboxamide derivative
MX2009012613A (es) * 2007-05-22 2010-04-21 Achillion Pharmaceuticals Inc Tiazoles substituidos por heteroarilo y su uso como agentes antivirales.
TW200906826A (en) * 2007-06-12 2009-02-16 Genelabs Tech Inc Anti-viral inhibitors and methods of use
ES2331220B1 (es) * 2007-10-02 2010-09-23 Palobiofarma, S.L. Nuevos compuestos como antagonistas de los receptores a1 de adenosina.
US8304547B2 (en) 2007-10-24 2012-11-06 Astellas Pharma Inc. Azolecarboxamide compound or salt thereof
AP2010005480A0 (en) * 2008-06-03 2010-12-31 Siga Technologies Inc Small molecule inhibitors for the treatment or prevention of denque virus infection.
US8106209B2 (en) * 2008-06-06 2012-01-31 Achillion Pharmaceuticals, Inc. Substituted aminothiazole prodrugs of compounds with anti-HCV activity
CA2733554A1 (en) * 2008-08-18 2010-02-25 Yale University Mif modulators
US9643922B2 (en) 2008-08-18 2017-05-09 Yale University MIF modulators
US9540322B2 (en) 2008-08-18 2017-01-10 Yale University MIF modulators
US8563742B2 (en) * 2008-08-29 2013-10-22 High Point Pharmaceuticals, Llc Substituted aminothiazole derivatives, pharmaceutical compositions, and methods of use
EP2391376A4 (en) 2009-01-30 2012-08-01 Enanta Pharm Inc ANALOGUES OF CYCLOSPORIN FOR PREVENTING OR TREATING HEPATITIS C INFECTION
US8481483B2 (en) * 2009-02-19 2013-07-09 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
US8367053B2 (en) * 2009-07-09 2013-02-05 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
US8685917B2 (en) * 2009-07-09 2014-04-01 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
US8349312B2 (en) * 2009-07-09 2013-01-08 Enanta Pharmaceuticals, Inc. Proline substituted cyclosporin analogues
US8623814B2 (en) * 2010-02-23 2014-01-07 Enanta Pharmaceuticals, Inc. Antiviral agents
WO2013052613A1 (en) * 2011-10-04 2013-04-11 Institute For Hepatitis And Virus Research Substituted aminothiazoles as inhibitors of cancers, including hepatocellular carcinoma, and as inhibitors of hepatitis virus replication
US8906853B2 (en) 2012-11-28 2014-12-09 Enanta Pharmaceuticals, Inc. [N-Me-4-hydroxyleucine]-9-cyclosporin analogues for treatment and prevention of hepatitis C infection
KR20160045136A (ko) 2013-08-26 2016-04-26 이난타 파마슈티칼스, 인코포레이티드 C형 간염을 예방 또는 치료하기 위한 사이클로스포린 유사체
WO2016073480A1 (en) 2014-11-03 2016-05-12 Enanta Pharmaceuticals, Inc. Novel cyclosporin analogues for preventing or treating hepatitis c infection

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3467666A (en) * 1966-11-07 1969-09-16 Geigy Chem Corp 2-substituted aminothiazoles
BE795907A (fr) * 1972-02-25 1973-06-18 Luso Farmaco Inst 2-amino-4-arylthiazoles 5-substitues et leur preparation
DE3406329A1 (de) * 1984-02-22 1985-08-22 Merck Patent Gmbh, 6100 Darmstadt Pyridone
KR100187990B1 (ko) 1992-12-29 1999-06-01 스티븐 에프. 웨인스톡 레트로바이러스성 프로테아제 억제 화합물 제조용 합성 중간체
AU689972B2 (en) * 1994-11-29 1998-04-09 Hisamitsu Pharmaceutical Co., Inc. Antibacterial preparation or bactericide comprising 2-aminothiazole derivative and/or salt thereof
US6323180B1 (en) 1998-08-10 2001-11-27 Boehringer Ingelheim (Canada) Ltd Hepatitis C inhibitor tri-peptides
JP2002526482A (ja) * 1998-09-18 2002-08-20 バーテックス ファーマシューティカルズ インコーポレイテッド p38のインヒビター
US7169931B2 (en) * 2001-01-26 2007-01-30 Shionogi & Co., Ltd. Cyclic compounds exhibiting thrombopoietin receptor agonism
MXPA04001399A (es) * 2001-08-13 2004-05-27 Janssen Pharmaceutica Nv Derivados de tiazolilo 2-amino-4,5-trisustituidos.
AU2002349705A1 (en) * 2001-12-03 2003-06-17 Japan Tobacco Inc. Azole compound and medicinal use thereof
EP1321463B1 (en) * 2001-12-21 2007-08-08 Virochem Pharma Inc. Thiazole derivatives and their use for the treatment or prevention of Flavivirus infections
CA2755297A1 (en) * 2003-02-10 2004-08-26 Vertex Pharmaceuticals Incorporated Processes for the preparation of n-heteroaryl-n-aryl-amines by reacting an n-aryl carbamic acid ester with a halo-heteroaryl and analogous processes
TW200505902A (en) * 2003-03-20 2005-02-16 Schering Corp Cannabinoid receptor ligands
JP4527729B2 (ja) * 2003-12-08 2010-08-18 エフ.ホフマン−ラ ロシュ アーゲー 新規チアゾール誘導体
KR20080019213A (ko) * 2005-05-09 2008-03-03 아칠리온 파르마세우티칼스 인코포레이티드 티아졸 화합물 및 그 사용방법
GB0513702D0 (en) * 2005-07-04 2005-08-10 Sterix Ltd Compound
MX2009012613A (es) * 2007-05-22 2010-04-21 Achillion Pharmaceuticals Inc Tiazoles substituidos por heteroarilo y su uso como agentes antivirales.
EP2217233B1 (en) * 2007-10-26 2018-08-08 New York University School of Medicine Methods and compositions for treating hepatic diseases
US8106209B2 (en) * 2008-06-06 2012-01-31 Achillion Pharmaceuticals, Inc. Substituted aminothiazole prodrugs of compounds with anti-HCV activity

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