JP2009528833A5 - - Google Patents
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- JP2009528833A5 JP2009528833A5 JP2008557833A JP2008557833A JP2009528833A5 JP 2009528833 A5 JP2009528833 A5 JP 2009528833A5 JP 2008557833 A JP2008557833 A JP 2008557833A JP 2008557833 A JP2008557833 A JP 2008557833A JP 2009528833 A5 JP2009528833 A5 JP 2009528833A5
- Authority
- JP
- Japan
- Prior art keywords
- isotope
- composition
- modified
- composition according
- component
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0604647.8A GB0604647D0 (en) | 2006-03-08 | 2006-03-08 | Stabilized food supplements and their derivatives |
| GB0604647.8 | 2006-03-08 | ||
| PCT/GB2007/050112 WO2007102030A1 (en) | 2006-03-08 | 2007-03-08 | Isotopically modified compounds and their use as food supplements |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015045737A Division JP6062470B2 (ja) | 2006-03-08 | 2015-03-09 | 同位体修飾化合物およびフードサプリメントとしてのそれらの使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009528833A JP2009528833A (ja) | 2009-08-13 |
| JP2009528833A5 true JP2009528833A5 (https=) | 2010-04-22 |
| JP5844955B2 JP5844955B2 (ja) | 2016-01-20 |
Family
ID=36241193
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008557833A Active JP5844955B2 (ja) | 2006-03-08 | 2007-03-08 | 同位体修飾化合物およびフードサプリメントとしてのそれらの使用 |
| JP2015045737A Active JP6062470B2 (ja) | 2006-03-08 | 2015-03-09 | 同位体修飾化合物およびフードサプリメントとしてのそれらの使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015045737A Active JP6062470B2 (ja) | 2006-03-08 | 2015-03-09 | 同位体修飾化合物およびフードサプリメントとしてのそれらの使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (5) | US8906405B2 (https=) |
| EP (2) | EP1991068B8 (https=) |
| JP (2) | JP5844955B2 (https=) |
| CA (2) | CA2645038C (https=) |
| DK (1) | DK1991068T3 (https=) |
| ES (1) | ES2639395T3 (https=) |
| GB (1) | GB0604647D0 (https=) |
| WO (1) | WO2007102030A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0604647D0 (en) | 2006-03-08 | 2006-04-19 | Shchepinov Mikhail | Stabilized food supplements and their derivatives |
| WO2009114814A2 (en) * | 2008-03-14 | 2009-09-17 | Retrotope, Inc. | Therapeutic substances that modulate genome methylation |
| CA2715036A1 (en) * | 2008-03-14 | 2009-09-17 | Retrotope, Inc. | Therapies for cancer using isotopically substituted lysine |
| CA2777827C (en) * | 2009-10-30 | 2020-08-18 | Retrotope, Inc. | Alleviating oxidative stress disorders with pufa derivatives |
| EP2588144B1 (en) | 2010-07-02 | 2018-05-09 | Ventana Medical Systems, Inc. | Detecting targets using mass tags and mass spectrometry |
| AU2012249917B2 (en) | 2011-04-26 | 2017-06-15 | Biojiva Llc | Neurodegenerative disorders and muscle diseases implicating PUFAs |
| EP3689342A1 (en) | 2011-04-26 | 2020-08-05 | Retrotope, Inc. | Oxidative retinal diseases |
| AU2012249918B2 (en) | 2011-04-26 | 2017-06-15 | Biojiva Llc | Impaired energy processing disorders and mitochondrial deficiency |
| AU2012249920B2 (en) * | 2011-04-26 | 2017-06-15 | Biojiva Llc | Disorders implicating PUFA oxidation |
| US20150284783A1 (en) * | 2012-05-21 | 2015-10-08 | Agena Bioscience, Inc. | Methods and compositions for analyzing nucleic acid |
| CN106170206A (zh) | 2014-03-13 | 2016-11-30 | 乐巢拓普有限公司 | 视神经病变治疗和用稳定的多不饱和物质减少类固醇诱导的氧化应激 |
| CA3005983A1 (en) | 2015-11-23 | 2017-06-01 | Retrotope, Inc. | Site-specific isotopic labeling of 1,4-diene systems |
| FR3068135B1 (fr) | 2017-06-26 | 2025-04-04 | Ids Group | Marquage et identification isotopiques des animaux et vegetaux |
| CA3096035A1 (en) * | 2018-04-04 | 2019-10-10 | Retrotope, Inc. | Isotopically modified composition and therapeutic uses thereof |
| MY204234A (en) | 2018-08-27 | 2024-08-16 | Regeneron Pharma | Use of raman spectroscopy in downstream purification |
| FR3091350B1 (fr) | 2019-01-02 | 2022-03-11 | Ids Group | Marquage et identification isotopiques des liquides |
| CA3172351A1 (en) | 2020-02-21 | 2021-08-26 | Retrotope, Inc. | Processes for isotopic modification of polyunsaturated fatty acids and derivatives thereof |
| KR20240096817A (ko) | 2020-05-19 | 2024-06-26 | 사이빈 아이알엘 리미티드 | 중수소화된 트립타민 유도체 및 사용 방법 |
| US12109194B2 (en) | 2021-02-05 | 2024-10-08 | Biojiva Llc | Synergistic combination therapy for treating ALS |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3520872A (en) * | 1967-03-24 | 1970-07-21 | Upjohn Co | Process for labelling purine and pyrimidine containing compounds |
| JPH07500566A (ja) * | 1989-11-30 | 1995-01-19 | クロダ・インターナショナル・ピーエルシー | ネルボン酸及び長鎖脂肪酸の脱髄疾患の治療のための使用 |
| US5244921A (en) | 1990-03-21 | 1993-09-14 | Martek Corporation | Eicosapentaenoic acids and methods for their production |
| US5393669A (en) | 1993-02-05 | 1995-02-28 | Martek Biosciences Corp. | Compositions and methods for protein structural determinations |
| FR2721518B3 (fr) | 1994-06-28 | 1996-04-12 | Gattefosse Ets Sa | Compositions cosmétiques, pharmaceutiques, diététiques, vétérinaires contenant de l'eau. |
| US5578334A (en) * | 1995-04-07 | 1996-11-26 | Brandeis University | Increasing the HDL level and the HDL/LDL ratio in human serum with fat blends |
| JPH10291955A (ja) | 1997-04-22 | 1998-11-04 | Sagami Chem Res Center | 13c標識ドコサヘキサエン酸及びその製造方法 |
| US6111066A (en) * | 1997-09-02 | 2000-08-29 | Martek Biosciences Corporation | Peptidic molecules which have been isotopically substituted with 13 C, 15 N and 2 H in the backbone but not in the sidechains |
| EP0991660B8 (en) | 1997-10-08 | 2006-04-05 | Isotechnika,Inc. | DEUTERATED and undeuterated CYCLOSPORINE ANALOGS AND THEIR USE AS IMMUNOMODULATING AGENTS |
| US6270974B1 (en) | 1998-03-13 | 2001-08-07 | Promega Corporation | Exogenous nucleic acid detection |
| EP1075286A2 (en) * | 1998-05-06 | 2001-02-14 | Isotechnika, Inc. | 13c glucose breath test for the diagnosis of diabetes |
| IT1304406B1 (it) * | 1998-10-21 | 2001-03-19 | Danital Italia S R L | Preparazione per la veicolazione di principi attivi basata su acidigrassi polinsaturi del gruppo omega 3. |
| US6503478B2 (en) * | 1999-01-13 | 2003-01-07 | Lightouch Medical, Inc. | Chemically specific imaging of tissue |
| JP2000290291A (ja) | 1999-03-31 | 2000-10-17 | Nippon Sanso Corp | 安定同位体標識オリゴヌクレオチド及びオリゴヌクレオチド検出方法 |
| GB9929897D0 (en) * | 1999-12-18 | 2000-02-09 | Slabas Antoni R | Improvements in or relating to conjugated fatty acids and related compounds |
| SK14502003A3 (en) * | 2001-05-30 | 2004-10-05 | Laxdale Ltd | Coenzyme Q and eicosapentaenoic acid |
| EP1548116A4 (en) * | 2002-09-30 | 2006-04-05 | Ajinomoto Kk | PROCESS FOR PRODUCING A PROTEIN MARKED BY A STABLE ISOTOPE |
| EP1644474B1 (en) | 2003-07-11 | 2012-06-27 | Tatiana A. Egorova-Zachernyuk | Compositions and methods for stable isotope labelling of biological compounds |
| JP2006053100A (ja) * | 2004-08-13 | 2006-02-23 | Institute Of Physical & Chemical Research | 動物の代謝解析方法、ラベル動物の製造方法、ラベル動物、および、動物のnmr測定方法 |
| EP1637163A1 (en) * | 2004-09-21 | 2006-03-22 | Andreas Kluge | Indicator of therapeutic compliance |
| WO2006055965A2 (en) * | 2004-11-19 | 2006-05-26 | Martek Biosciences Corporation | Oxylipins from long chain polyunsaturated fatty acids and methods of making and using the same |
| US7250416B2 (en) | 2005-03-11 | 2007-07-31 | Supergen, Inc. | Azacytosine analogs and derivatives |
| GB0604647D0 (en) | 2006-03-08 | 2006-04-19 | Shchepinov Mikhail | Stabilized food supplements and their derivatives |
| US20080234197A1 (en) * | 2007-03-19 | 2008-09-25 | Undurti N Das | Method(s) of stabilizing and potentiating the actions and administration of brain-derived neurotrophic factor (BDNF) |
| CA2693310C (en) | 2007-08-02 | 2018-11-27 | Arresto Biosciences, Inc. | Lox and loxl2 inhibitors, antibodies and uses thereof |
| US20090069354A1 (en) * | 2007-09-12 | 2009-03-12 | Protia, Llc | Deuterium-enriched gemcitabine |
| CA2715036A1 (en) | 2008-03-14 | 2009-09-17 | Retrotope, Inc. | Therapies for cancer using isotopically substituted lysine |
| WO2009114814A2 (en) | 2008-03-14 | 2009-09-17 | Retrotope, Inc. | Therapeutic substances that modulate genome methylation |
-
2006
- 2006-03-08 GB GBGB0604647.8A patent/GB0604647D0/en not_active Ceased
-
2007
- 2007-03-08 US US12/281,957 patent/US8906405B2/en active Active
- 2007-03-08 CA CA2645038A patent/CA2645038C/en active Active
- 2007-03-08 JP JP2008557833A patent/JP5844955B2/ja active Active
- 2007-03-08 DK DK07712990.6T patent/DK1991068T3/en active
- 2007-03-08 ES ES07712990.6T patent/ES2639395T3/es active Active
- 2007-03-08 CA CA2931996A patent/CA2931996A1/en not_active Abandoned
- 2007-03-08 EP EP07712990.6A patent/EP1991068B8/en active Active
- 2007-03-08 EP EP17174428.7A patent/EP3339315B1/en active Active
- 2007-03-08 WO PCT/GB2007/050112 patent/WO2007102030A1/en not_active Ceased
-
2014
- 2014-11-24 US US14/551,450 patent/US9320289B2/en active Active
-
2015
- 2015-03-09 JP JP2015045737A patent/JP6062470B2/ja active Active
-
2016
- 2016-03-23 US US15/078,853 patent/US9616042B2/en active Active
-
2017
- 2017-03-01 US US15/446,922 patent/US10015979B2/en active Active
-
2018
- 2018-06-22 US US16/016,023 patent/US10918126B2/en active Active
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