JP2009528833A5 - - Google Patents
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- JP2009528833A5 JP2009528833A5 JP2008557833A JP2008557833A JP2009528833A5 JP 2009528833 A5 JP2009528833 A5 JP 2009528833A5 JP 2008557833 A JP2008557833 A JP 2008557833A JP 2008557833 A JP2008557833 A JP 2008557833A JP 2009528833 A5 JP2009528833 A5 JP 2009528833A5
- Authority
- JP
- Japan
- Prior art keywords
- isotope
- composition
- modified
- composition according
- component
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0604647.8A GB0604647D0 (en) | 2006-03-08 | 2006-03-08 | Stabilized food supplements and their derivatives |
| GB0604647.8 | 2006-03-08 | ||
| PCT/GB2007/050112 WO2007102030A1 (en) | 2006-03-08 | 2007-03-08 | Isotopically modified compounds and their use as food supplements |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015045737A Division JP6062470B2 (ja) | 2006-03-08 | 2015-03-09 | 同位体修飾化合物およびフードサプリメントとしてのそれらの使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009528833A JP2009528833A (ja) | 2009-08-13 |
| JP2009528833A5 true JP2009528833A5 (https=) | 2010-04-22 |
| JP5844955B2 JP5844955B2 (ja) | 2016-01-20 |
Family
ID=36241193
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008557833A Active JP5844955B2 (ja) | 2006-03-08 | 2007-03-08 | 同位体修飾化合物およびフードサプリメントとしてのそれらの使用 |
| JP2015045737A Active JP6062470B2 (ja) | 2006-03-08 | 2015-03-09 | 同位体修飾化合物およびフードサプリメントとしてのそれらの使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015045737A Active JP6062470B2 (ja) | 2006-03-08 | 2015-03-09 | 同位体修飾化合物およびフードサプリメントとしてのそれらの使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (5) | US8906405B2 (https=) |
| EP (2) | EP3339315B1 (https=) |
| JP (2) | JP5844955B2 (https=) |
| CA (2) | CA2645038C (https=) |
| DK (1) | DK1991068T3 (https=) |
| ES (1) | ES2639395T3 (https=) |
| GB (1) | GB0604647D0 (https=) |
| WO (1) | WO2007102030A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0604647D0 (en) | 2006-03-08 | 2006-04-19 | Shchepinov Mikhail | Stabilized food supplements and their derivatives |
| US8637486B2 (en) | 2008-03-14 | 2014-01-28 | Retrotope, Inc. | Therapeutic substances that modulate genome methylation |
| JP2011514361A (ja) * | 2008-03-14 | 2011-05-06 | レトロトップ、 インコーポレイテッド | 同位体で置換されたリジンを用いたがん治療 |
| US10052299B2 (en) | 2009-10-30 | 2018-08-21 | Retrotope, Inc. | Alleviating oxidative stress disorders with PUFA derivatives |
| ES2676183T3 (es) | 2010-07-02 | 2018-07-17 | Ventana Medical Systems, Inc. | Detección de dianas usando marcas de masa y espectrometría de masas |
| KR102112087B1 (ko) | 2011-04-26 | 2020-05-18 | 레트로토프 인코포레이티드 | 에너지 프로세싱 손상 장애 및 미토콘드리아 결함 |
| JP6145087B2 (ja) * | 2011-04-26 | 2017-06-07 | レトロトップ、 インコーポレイテッドＲｅｔｒｏｔｏｐｅ， Ｉｎｃ． | Ｐｕｆａ酸化関与障害 |
| WO2012148930A2 (en) | 2011-04-26 | 2012-11-01 | Retrotope, Inc. | Oxidative retinal diseases |
| JP6106157B2 (ja) | 2011-04-26 | 2017-03-29 | レトロトップ、 インコーポレイテッドＲｅｔｒｏｔｏｐｅ， Ｉｎｃ． | 神経変性障害および筋疾患に関与するｐｕｆａ |
| US20150284783A1 (en) * | 2012-05-21 | 2015-10-08 | Agena Bioscience, Inc. | Methods and compositions for analyzing nucleic acid |
| AU2015229240B9 (en) | 2014-03-13 | 2019-05-02 | Biojiva Llc | Optic neuropathy treatment and reduction of steroid-induced oxidative stress with stabilized polyunsaturated substances |
| EP3950649A1 (en) * | 2015-11-23 | 2022-02-09 | Retrotope, Inc. | Site-specific isotopic labeling of 1, 4-diene systems |
| FR3068135B1 (fr) | 2017-06-26 | 2025-04-04 | Ids Group | Marquage et identification isotopiques des animaux et vegetaux |
| EP3773541A4 (en) * | 2018-04-04 | 2022-01-05 | Retrotope, Inc. | ISOTOPICALLY MODIFIED COMPOSITION AND ITS THERAPEUTIC USES |
| CN119264211A (zh) | 2018-08-27 | 2025-01-07 | 瑞泽恩制药公司 | 拉曼光谱在下游纯化中的应用 |
| FR3091350B1 (fr) | 2019-01-02 | 2022-03-11 | Ids Group | Marquage et identification isotopiques des liquides |
| IL295783B2 (en) | 2020-02-21 | 2026-03-01 | Retrotope Inc | Processes for isotopic alteration of polyunsaturated fatty acids and their derivatives |
| US12240813B2 (en) | 2020-05-19 | 2025-03-04 | Cybin Irl Limited | Deuterated tryptamine derivatives and methods of use |
| US12109194B2 (en) | 2021-02-05 | 2024-10-08 | Biojiva Llc | Synergistic combination therapy for treating ALS |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3520872A (en) | 1967-03-24 | 1970-07-21 | Upjohn Co | Process for labelling purine and pyrimidine containing compounds |
| DK0455783T3 (da) | 1989-11-30 | 1996-04-01 | Croda Int Plc | Anvendelse af nervonsyre og langkædede fedtsyrer til behandlingen af demyeliniserende sygdomme |
| US5244921A (en) | 1990-03-21 | 1993-09-14 | Martek Corporation | Eicosapentaenoic acids and methods for their production |
| US5393669A (en) | 1993-02-05 | 1995-02-28 | Martek Biosciences Corp. | Compositions and methods for protein structural determinations |
| FR2721518B3 (fr) * | 1994-06-28 | 1996-04-12 | Gattefosse Ets Sa | Compositions cosmétiques, pharmaceutiques, diététiques, vétérinaires contenant de l'eau. |
| US5578334A (en) | 1995-04-07 | 1996-11-26 | Brandeis University | Increasing the HDL level and the HDL/LDL ratio in human serum with fat blends |
| JPH10291955A (ja) | 1997-04-22 | 1998-11-04 | Sagami Chem Res Center | １３ｃ標識ドコサヘキサエン酸及びその製造方法 |
| US6111066A (en) * | 1997-09-02 | 2000-08-29 | Martek Biosciences Corporation | Peptidic molecules which have been isotopically substituted with 13 C, 15 N and 2 H in the backbone but not in the sidechains |
| AU750245B2 (en) | 1997-10-08 | 2002-07-11 | Aurinia Phamaceuticals Inc. | Deuterated cyclosporine analogs and their use as immunomodulating agents |
| US6270974B1 (en) * | 1998-03-13 | 2001-08-07 | Promega Corporation | Exogenous nucleic acid detection |
| EP1075286A2 (en) | 1998-05-06 | 2001-02-14 | Isotechnika, Inc. | 13c glucose breath test for the diagnosis of diabetes |
| IT1304406B1 (it) | 1998-10-21 | 2001-03-19 | Danital Italia S R L | Preparazione per la veicolazione di principi attivi basata su acidigrassi polinsaturi del gruppo omega 3. |
| US6503478B2 (en) * | 1999-01-13 | 2003-01-07 | Lightouch Medical, Inc. | Chemically specific imaging of tissue |
| JP2000290291A (ja) * | 1999-03-31 | 2000-10-17 | Nippon Sanso Corp | 安定同位体標識オリゴヌクレオチド及びオリゴヌクレオチド検出方法 |
| GB9929897D0 (en) | 1999-12-18 | 2000-02-09 | Slabas Antoni R | Improvements in or relating to conjugated fatty acids and related compounds |
| ATE291910T1 (de) | 2001-05-30 | 2005-04-15 | Laxdale Ltd | Verwendung von coenzym q (ubiquinone) und eikosapentaensäure (epa) für die behandlung von non-hodgkin's lymphoma und psychiatrischen oder neurologischen erkrankungen |
| AU2003268693A1 (en) | 2002-09-30 | 2004-04-19 | Ajinomoto Co., Inc. | Method of producing stable isotope-labeled protein |
| WO2005005616A2 (en) | 2003-07-11 | 2005-01-20 | Egorova-Zachernyuk Tatiana A | Compositions and methods for stable isotope labelling of biological compounds |
| JP2006053100A (ja) | 2004-08-13 | 2006-02-23 | Institute Of Physical & Chemical Research | 動物の代謝解析方法、ラベル動物の製造方法、ラベル動物、および、動物のｎｍｒ測定方法 |
| EP1637163A1 (en) * | 2004-09-21 | 2006-03-22 | Andreas Kluge | Indicator of therapeutic compliance |
| BRPI0516803A (pt) | 2004-11-19 | 2008-09-23 | Martek Biosciences Corp | oxilipinas de ácidos graxos polinsaturados de cadeia longa e métodos de produção e uso dos mesmos |
| US7250416B2 (en) | 2005-03-11 | 2007-07-31 | Supergen, Inc. | Azacytosine analogs and derivatives |
| GB0604647D0 (en) | 2006-03-08 | 2006-04-19 | Shchepinov Mikhail | Stabilized food supplements and their derivatives |
| US20080234197A1 (en) | 2007-03-19 | 2008-09-25 | Undurti N Das | Method(s) of stabilizing and potentiating the actions and administration of brain-derived neurotrophic factor (BDNF) |
| ES2700141T3 (es) | 2007-08-02 | 2019-02-14 | Gilead Biologics Inc | Anticuerpos inhibidores LOXL2 y usos de los mismos |
| US20090069354A1 (en) | 2007-09-12 | 2009-03-12 | Protia, Llc | Deuterium-enriched gemcitabine |
| US8637486B2 (en) | 2008-03-14 | 2014-01-28 | Retrotope, Inc. | Therapeutic substances that modulate genome methylation |
| JP2011514361A (ja) | 2008-03-14 | 2011-05-06 | レトロトップ、 インコーポレイテッド | 同位体で置換されたリジンを用いたがん治療 |
-
2006
- 2006-03-08 GB GBGB0604647.8A patent/GB0604647D0/en not_active Ceased
-
2007
- 2007-03-08 EP EP17174428.7A patent/EP3339315B1/en active Active
- 2007-03-08 ES ES07712990.6T patent/ES2639395T3/es active Active
- 2007-03-08 JP JP2008557833A patent/JP5844955B2/ja active Active
- 2007-03-08 CA CA2645038A patent/CA2645038C/en active Active
- 2007-03-08 EP EP07712990.6A patent/EP1991068B8/en active Active
- 2007-03-08 CA CA2931996A patent/CA2931996A1/en not_active Abandoned
- 2007-03-08 US US12/281,957 patent/US8906405B2/en active Active
- 2007-03-08 DK DK07712990.6T patent/DK1991068T3/en active
- 2007-03-08 WO PCT/GB2007/050112 patent/WO2007102030A1/en not_active Ceased
-
2014
- 2014-11-24 US US14/551,450 patent/US9320289B2/en active Active
-
2015
- 2015-03-09 JP JP2015045737A patent/JP6062470B2/ja active Active
-
2016
- 2016-03-23 US US15/078,853 patent/US9616042B2/en active Active
-
2017
- 2017-03-01 US US15/446,922 patent/US10015979B2/en active Active
-
2018
- 2018-06-22 US US16/016,023 patent/US10918126B2/en active Active
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