ES2639395T3 - Compuestos modificados isotópicamente y su uso como complementos alimentarios - Google Patents
Compuestos modificados isotópicamente y su uso como complementos alimentarios Download PDFInfo
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- ES2639395T3 ES2639395T3 ES07712990.6T ES07712990T ES2639395T3 ES 2639395 T3 ES2639395 T3 ES 2639395T3 ES 07712990 T ES07712990 T ES 07712990T ES 2639395 T3 ES2639395 T3 ES 2639395T3
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| PCT/GB2007/050112 WO2007102030A1 (en) | 2006-03-08 | 2007-03-08 | Isotopically modified compounds and their use as food supplements |
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| GB0604647D0 (en) | 2006-03-08 | 2006-04-19 | Shchepinov Mikhail | Stabilized food supplements and their derivatives |
| WO2009114814A2 (en) * | 2008-03-14 | 2009-09-17 | Retrotope, Inc. | Therapeutic substances that modulate genome methylation |
| CA2715036A1 (en) * | 2008-03-14 | 2009-09-17 | Retrotope, Inc. | Therapies for cancer using isotopically substituted lysine |
| CA2777827C (en) * | 2009-10-30 | 2020-08-18 | Retrotope, Inc. | Alleviating oxidative stress disorders with pufa derivatives |
| EP2588144B1 (en) | 2010-07-02 | 2018-05-09 | Ventana Medical Systems, Inc. | Detecting targets using mass tags and mass spectrometry |
| AU2012249917B2 (en) | 2011-04-26 | 2017-06-15 | Biojiva Llc | Neurodegenerative disorders and muscle diseases implicating PUFAs |
| EP3689342A1 (en) | 2011-04-26 | 2020-08-05 | Retrotope, Inc. | Oxidative retinal diseases |
| AU2012249918B2 (en) | 2011-04-26 | 2017-06-15 | Biojiva Llc | Impaired energy processing disorders and mitochondrial deficiency |
| AU2012249920B2 (en) * | 2011-04-26 | 2017-06-15 | Biojiva Llc | Disorders implicating PUFA oxidation |
| US20150284783A1 (en) * | 2012-05-21 | 2015-10-08 | Agena Bioscience, Inc. | Methods and compositions for analyzing nucleic acid |
| CN106170206A (zh) | 2014-03-13 | 2016-11-30 | 乐巢拓普有限公司 | 视神经病变治疗和用稳定的多不饱和物质减少类固醇诱导的氧化应激 |
| CA3005983A1 (en) | 2015-11-23 | 2017-06-01 | Retrotope, Inc. | Site-specific isotopic labeling of 1,4-diene systems |
| FR3068135B1 (fr) | 2017-06-26 | 2025-04-04 | Ids Group | Marquage et identification isotopiques des animaux et vegetaux |
| CA3096035A1 (en) * | 2018-04-04 | 2019-10-10 | Retrotope, Inc. | Isotopically modified composition and therapeutic uses thereof |
| MY204234A (en) | 2018-08-27 | 2024-08-16 | Regeneron Pharma | Use of raman spectroscopy in downstream purification |
| FR3091350B1 (fr) | 2019-01-02 | 2022-03-11 | Ids Group | Marquage et identification isotopiques des liquides |
| CA3172351A1 (en) | 2020-02-21 | 2021-08-26 | Retrotope, Inc. | Processes for isotopic modification of polyunsaturated fatty acids and derivatives thereof |
| KR20240096817A (ko) | 2020-05-19 | 2024-06-26 | 사이빈 아이알엘 리미티드 | 중수소화된 트립타민 유도체 및 사용 방법 |
| US12109194B2 (en) | 2021-02-05 | 2024-10-08 | Biojiva Llc | Synergistic combination therapy for treating ALS |
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| JPH07500566A (ja) * | 1989-11-30 | 1995-01-19 | クロダ・インターナショナル・ピーエルシー | ネルボン酸及び長鎖脂肪酸の脱髄疾患の治療のための使用 |
| US5244921A (en) | 1990-03-21 | 1993-09-14 | Martek Corporation | Eicosapentaenoic acids and methods for their production |
| US5393669A (en) | 1993-02-05 | 1995-02-28 | Martek Biosciences Corp. | Compositions and methods for protein structural determinations |
| FR2721518B3 (fr) | 1994-06-28 | 1996-04-12 | Gattefosse Ets Sa | Compositions cosmétiques, pharmaceutiques, diététiques, vétérinaires contenant de l'eau. |
| US5578334A (en) * | 1995-04-07 | 1996-11-26 | Brandeis University | Increasing the HDL level and the HDL/LDL ratio in human serum with fat blends |
| JPH10291955A (ja) | 1997-04-22 | 1998-11-04 | Sagami Chem Res Center | １３ｃ標識ドコサヘキサエン酸及びその製造方法 |
| US6111066A (en) * | 1997-09-02 | 2000-08-29 | Martek Biosciences Corporation | Peptidic molecules which have been isotopically substituted with 13 C, 15 N and 2 H in the backbone but not in the sidechains |
| EP0991660B8 (en) | 1997-10-08 | 2006-04-05 | Isotechnika,Inc. | DEUTERATED and undeuterated CYCLOSPORINE ANALOGS AND THEIR USE AS IMMUNOMODULATING AGENTS |
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| EP1075286A2 (en) * | 1998-05-06 | 2001-02-14 | Isotechnika, Inc. | 13c glucose breath test for the diagnosis of diabetes |
| IT1304406B1 (it) * | 1998-10-21 | 2001-03-19 | Danital Italia S R L | Preparazione per la veicolazione di principi attivi basata su acidigrassi polinsaturi del gruppo omega 3. |
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| GB9929897D0 (en) * | 1999-12-18 | 2000-02-09 | Slabas Antoni R | Improvements in or relating to conjugated fatty acids and related compounds |
| SK14502003A3 (en) * | 2001-05-30 | 2004-10-05 | Laxdale Ltd | Coenzyme Q and eicosapentaenoic acid |
| EP1548116A4 (en) * | 2002-09-30 | 2006-04-05 | Ajinomoto Kk | PROCESS FOR PRODUCING A PROTEIN MARKED BY A STABLE ISOTOPE |
| EP1644474B1 (en) | 2003-07-11 | 2012-06-27 | Tatiana A. Egorova-Zachernyuk | Compositions and methods for stable isotope labelling of biological compounds |
| JP2006053100A (ja) * | 2004-08-13 | 2006-02-23 | Institute Of Physical & Chemical Research | 動物の代謝解析方法、ラベル動物の製造方法、ラベル動物、および、動物のｎｍｒ測定方法 |
| EP1637163A1 (en) * | 2004-09-21 | 2006-03-22 | Andreas Kluge | Indicator of therapeutic compliance |
| WO2006055965A2 (en) * | 2004-11-19 | 2006-05-26 | Martek Biosciences Corporation | Oxylipins from long chain polyunsaturated fatty acids and methods of making and using the same |
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| GB0604647D0 (en) | 2006-03-08 | 2006-04-19 | Shchepinov Mikhail | Stabilized food supplements and their derivatives |
| US20080234197A1 (en) * | 2007-03-19 | 2008-09-25 | Undurti N Das | Method(s) of stabilizing and potentiating the actions and administration of brain-derived neurotrophic factor (BDNF) |
| CA2693310C (en) | 2007-08-02 | 2018-11-27 | Arresto Biosciences, Inc. | Lox and loxl2 inhibitors, antibodies and uses thereof |
| US20090069354A1 (en) * | 2007-09-12 | 2009-03-12 | Protia, Llc | Deuterium-enriched gemcitabine |
| CA2715036A1 (en) | 2008-03-14 | 2009-09-17 | Retrotope, Inc. | Therapies for cancer using isotopically substituted lysine |
| WO2009114814A2 (en) | 2008-03-14 | 2009-09-17 | Retrotope, Inc. | Therapeutic substances that modulate genome methylation |
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Also Published As
| Publication number | Publication date |
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| HK1260326A1 (en) | 2019-12-20 |
| JP2009528833A (ja) | 2009-08-13 |
| US8906405B2 (en) | 2014-12-09 |
| US10015979B2 (en) | 2018-07-10 |
| DK1991068T3 (en) | 2017-09-11 |
| US10918126B2 (en) | 2021-02-16 |
| CA2931996A1 (en) | 2007-09-13 |
| US20170172195A1 (en) | 2017-06-22 |
| EP3339315A1 (en) | 2018-06-27 |
| US9616042B2 (en) | 2017-04-11 |
| CA2645038A1 (en) | 2007-09-13 |
| EP3339315C0 (en) | 2023-10-18 |
| US20150147457A1 (en) | 2015-05-28 |
| CA2645038C (en) | 2016-08-16 |
| JP6062470B2 (ja) | 2017-01-18 |
| EP1991068B8 (en) | 2018-10-17 |
| US20180303145A1 (en) | 2018-10-25 |
| EP1991068A1 (en) | 2008-11-19 |
| US20160263066A1 (en) | 2016-09-15 |
| US20100160248A1 (en) | 2010-06-24 |
| JP5844955B2 (ja) | 2016-01-20 |
| WO2007102030A1 (en) | 2007-09-13 |
| JP2015146811A (ja) | 2015-08-20 |
| EP1991068B1 (en) | 2017-06-07 |
| US9320289B2 (en) | 2016-04-26 |
| EP3339315B1 (en) | 2023-10-18 |
| GB0604647D0 (en) | 2006-04-19 |
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