JP2009526084A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2009526084A5 JP2009526084A5 JP2008554516A JP2008554516A JP2009526084A5 JP 2009526084 A5 JP2009526084 A5 JP 2009526084A5 JP 2008554516 A JP2008554516 A JP 2008554516A JP 2008554516 A JP2008554516 A JP 2008554516A JP 2009526084 A5 JP2009526084 A5 JP 2009526084A5
- Authority
- JP
- Japan
- Prior art keywords
- disease
- pharmaceutical composition
- composition according
- inflammatory
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 11
- 208000027866 inflammatory disease Diseases 0.000 claims 8
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims 5
- 229920001184 polypeptide Polymers 0.000 claims 5
- 102000004196 processed proteins & peptides Human genes 0.000 claims 5
- 108090000765 processed proteins & peptides Proteins 0.000 claims 5
- 102000013691 Interleukin-17 Human genes 0.000 claims 4
- 108050003558 Interleukin-17 Proteins 0.000 claims 4
- 208000023275 Autoimmune disease Diseases 0.000 claims 2
- 208000009329 Graft vs Host Disease Diseases 0.000 claims 2
- 102000006496 Immunoglobulin Heavy Chains Human genes 0.000 claims 2
- 108010019476 Immunoglobulin Heavy Chains Proteins 0.000 claims 2
- 206010061218 Inflammation Diseases 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 claims 2
- 230000001154 acute effect Effects 0.000 claims 2
- 206010003246 arthritis Diseases 0.000 claims 2
- 230000001684 chronic effect Effects 0.000 claims 2
- 208000037976 chronic inflammation Diseases 0.000 claims 2
- 208000037893 chronic inflammatory disorder Diseases 0.000 claims 2
- 208000024908 graft versus host disease Diseases 0.000 claims 2
- 230000002757 inflammatory effect Effects 0.000 claims 2
- 230000004054 inflammatory process Effects 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 201000006417 multiple sclerosis Diseases 0.000 claims 2
- 208000023504 respiratory system disease Diseases 0.000 claims 2
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 2
- 201000000596 systemic lupus erythematosus Diseases 0.000 claims 2
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 claims 1
- 206010009900 Colitis ulcerative Diseases 0.000 claims 1
- 208000011231 Crohn disease Diseases 0.000 claims 1
- 201000003883 Cystic fibrosis Diseases 0.000 claims 1
- 206010012438 Dermatitis atopic Diseases 0.000 claims 1
- 208000037487 Endotoxemia Diseases 0.000 claims 1
- 102000018071 Immunoglobulin Fc Fragments Human genes 0.000 claims 1
- 108010091135 Immunoglobulin Fc Fragments Proteins 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 201000001263 Psoriatic Arthritis Diseases 0.000 claims 1
- 208000036824 Psoriatic arthropathy Diseases 0.000 claims 1
- 206010040047 Sepsis Diseases 0.000 claims 1
- 206010040070 Septic Shock Diseases 0.000 claims 1
- 206010044248 Toxic shock syndrome Diseases 0.000 claims 1
- 231100000650 Toxic shock syndrome Toxicity 0.000 claims 1
- 206010052779 Transplant rejections Diseases 0.000 claims 1
- 201000006704 Ulcerative Colitis Diseases 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 208000006673 asthma Diseases 0.000 claims 1
- 201000008937 atopic dermatitis Diseases 0.000 claims 1
- 108020001507 fusion proteins Proteins 0.000 claims 1
- 102000037865 fusion proteins Human genes 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 206010028417 myasthenia gravis Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77217706P | 2006-02-10 | 2006-02-10 | |
| US78107806P | 2006-03-10 | 2006-03-10 | |
| PCT/US2007/061909 WO2008039553A1 (en) | 2006-02-10 | 2007-02-09 | Soluble il-17rcx4 and methods of using in inflammation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009526084A JP2009526084A (ja) | 2009-07-16 |
| JP2009526084A5 true JP2009526084A5 (cg-RX-API-DMAC7.html) | 2010-03-18 |
Family
ID=38895865
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008554516A Pending JP2009526084A (ja) | 2006-02-10 | 2007-02-09 | 可溶性ＩＬ−１７ＲＣｘ４および炎症における使用法 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7622116B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1987058B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2009526084A (cg-RX-API-DMAC7.html) |
| AT (1) | ATE467640T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2007300393B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2638819A1 (cg-RX-API-DMAC7.html) |
| DE (1) | DE602007006429D1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2347840T3 (cg-RX-API-DMAC7.html) |
| IL (1) | IL192950A0 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008039553A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0511952A (pt) * | 2004-06-10 | 2008-01-29 | Zymogenetics Inc | receptor solúvel isolado, anticorpo ou fragmento de anticorpo, e, métodos de reduzir inflamação induzida por il-17a ou induzida por il-17f, de tratar um mamìfero afetado com uma doença inflamatória, e uma condição patológica em um indivìduo associada com atividade de zcytor14 |
| JP2010522564A (ja) | 2007-03-26 | 2010-07-08 | ザイモジェネティクス， インコーポレイテッド | 可溶性ｉｌ−１７ｒａ／ｒｃ融合タンパク質および関連する方法 |
| WO2008156865A2 (en) * | 2007-06-20 | 2008-12-24 | Schering Corporation | Joint destruction biomarkers for anti-il-17a therapy of inflammatory joint disease |
| GB2464183A (en) * | 2008-09-19 | 2010-04-14 | Singulex Inc | Sandwich assay |
| US9238878B2 (en) | 2009-02-17 | 2016-01-19 | Redwood Bioscience, Inc. | Aldehyde-tagged protein-based drug carriers and methods of use |
| PE20160651A1 (es) * | 2009-03-05 | 2016-07-24 | Abbvie Inc | Proteinas de union a il-17 |
| EP2440936A4 (en) | 2009-06-08 | 2013-03-13 | Singulex Inc | GROUPS OF HIGHLY SENSITIVE BIOMARKERS |
| JP2011032170A (ja) * | 2009-07-29 | 2011-02-17 | Morinaga Milk Ind Co Ltd | ヒト細胞ｉｌ−１７産生抑制剤 |
| WO2011096438A1 (ja) * | 2010-02-03 | 2011-08-11 | 国立大学法人 東京大学 | 腸疾患の治療方法及び治療用医薬組成物 |
| US20110301053A1 (en) | 2010-05-06 | 2011-12-08 | Singulex, Inc. | Methods for Diagnosing, Staging, Predicting Risk for Developing and Identifying Treatment Responders for Rheumatoid Arthritis |
| RU2535033C2 (ru) * | 2010-08-06 | 2014-12-10 | Олег Ильич Эпштейн | Лекарственное средство и способ профилактики инфицирования вич, профилактики и лечения заболеваний, вызываемых вич или ассоциированных с вич, в том числе спида |
| AU2012205301B2 (en) | 2011-01-14 | 2017-01-05 | Redwood Bioscience, Inc. | Aldehyde-tagged immunoglobulin polypeptides and method of use thereof |
| US9284283B2 (en) | 2012-02-02 | 2016-03-15 | Ensemble Therapeutics Corporation | Macrocyclic compounds for modulating IL-17 |
| CA3001260A1 (en) | 2015-10-27 | 2017-05-04 | Ucb Biopharma Sprl | Methods of treatment using anti-il-17a/f antibodies |
| US11208632B2 (en) | 2016-04-26 | 2021-12-28 | R.P. Scherer Technologies, Llc | Antibody conjugates and methods of making and using the same |
| CN114107385A (zh) * | 2019-01-17 | 2022-03-01 | 百奥赛图(北京)医药科技股份有限公司 | 人源化转基因动物 |
| BR112022002962A2 (pt) | 2019-08-16 | 2022-07-05 | Applied Molecular Transport Inc | Composições, formulações e produção e purificação de interleucina |
| CN112250764B (zh) * | 2020-10-22 | 2022-07-29 | 深圳市康瑞克生物科技有限责任公司 | 一种抗白细胞介素17a的单克隆抗体、其编码基因及应用 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5684032A (en) * | 1994-12-13 | 1997-11-04 | Smithkline Beecham Corporation | Compounds |
| US5869286A (en) | 1995-03-23 | 1999-02-09 | Immunex Corporation | Receptor that binds IL-17 |
| US5945511A (en) | 1997-02-20 | 1999-08-31 | Zymogenetics, Inc. | Class II cytokine receptor |
| US6579520B2 (en) * | 1998-05-15 | 2003-06-17 | Genentech, Inc. | IL-17 related mammalian cytokine polypeptides (IL-17E) |
| US20020177188A1 (en) * | 1998-05-15 | 2002-11-28 | Genentech, Inc. | IL-17 homologous polypeptides and therapeutic uses thereof |
| US6569645B2 (en) * | 1999-05-14 | 2003-05-27 | Genentech, Inc. | IL-17 homologous polypeptides and therapeutic uses thereof |
| WO1998049307A1 (en) | 1997-05-01 | 1998-11-05 | Zymogenetics, Inc. | Mammalian cytokine-like receptor |
| US5965704A (en) | 1997-08-05 | 1999-10-12 | Zymogenetics, Inc. | Class two cytokine receptor-11 |
| US6635443B1 (en) | 1997-09-17 | 2003-10-21 | Human Genome Sciences, Inc. | Polynucleotides encoding a novel interleukin receptor termed interleukin-17 receptor-like protein |
| CA2332109A1 (en) | 1998-05-12 | 1999-11-18 | Human Genome Sciences, Inc. | 97 human secreted proteins |
| ATE508193T1 (de) | 1999-07-07 | 2011-05-15 | Zymogenetics Inc | Menschliches rezeptor für zytokine |
| US20030199041A1 (en) * | 1999-07-07 | 2003-10-23 | Presnell Scott R. | Interleukin-17 receptor homologue |
| ES2380812T3 (es) | 1999-12-23 | 2012-05-18 | Genentech, Inc. | Polipéptidos homólogos a IL-17 y usos terapéuticos de los mismos |
| AU2001274920A1 (en) * | 2000-05-24 | 2001-12-03 | Schering Corporation | Mammalian receptor proteins; related reagents and methods |
| AU2001260847A1 (en) | 2000-05-24 | 2001-12-03 | Genesis Research And Development Corporation Limited | Compositions isolated from skin cells and methods for their use |
| MXPA03003407A (es) * | 2000-10-18 | 2004-05-04 | Immunex Corp | Metodos para el tratamiento de artritis reumatoide usando antagonistas il-17. |
| AU2002225714A1 (en) * | 2000-11-10 | 2002-05-21 | The Regents Of The University Of California | Il-17 receptor-like protein, uses thereof, and modulation of catabolic activity of il-17 cytokines on bone and cartilage |
| US20040097447A1 (en) * | 2002-11-16 | 2004-05-20 | Isis Pharmaceuticals Inc. | Modulation of interleukin 22 receptor expression |
| BRPI0511952A (pt) * | 2004-06-10 | 2008-01-29 | Zymogenetics Inc | receptor solúvel isolado, anticorpo ou fragmento de anticorpo, e, métodos de reduzir inflamação induzida por il-17a ou induzida por il-17f, de tratar um mamìfero afetado com uma doença inflamatória, e uma condição patológica em um indivìduo associada com atividade de zcytor14 |
| KR20070107703A (ko) * | 2005-02-14 | 2007-11-07 | 와이어쓰 | 인터루킨-１７ｆ 항체 및 기타 ｉｌ-１７ｆ 신호전달안타고니스트 및 그의 용도 |
| DK1931697T3 (da) * | 2005-09-28 | 2010-11-08 | Zymogenetics Inc | IL-17A og IL-17F-antagonister og fremgangsmåder til anvendelse af disse |
| US20070249533A1 (en) * | 2005-09-28 | 2007-10-25 | Levin Steven D | Il-17a and il-17f antagonists and methods of using the same |
-
2007
- 2007-02-09 AT AT07863316T patent/ATE467640T1/de active
- 2007-02-09 EP EP07863316A patent/EP1987058B1/en not_active Not-in-force
- 2007-02-09 WO PCT/US2007/061909 patent/WO2008039553A1/en not_active Ceased
- 2007-02-09 ES ES07863316T patent/ES2347840T3/es active Active
- 2007-02-09 AU AU2007300393A patent/AU2007300393B2/en not_active Expired - Fee Related
- 2007-02-09 CA CA002638819A patent/CA2638819A1/en not_active Abandoned
- 2007-02-09 DE DE602007006429T patent/DE602007006429D1/de active Active
- 2007-02-09 US US11/673,094 patent/US7622116B2/en active Active
- 2007-02-09 JP JP2008554516A patent/JP2009526084A/ja active Pending
-
2008
- 2008-07-22 IL IL192950A patent/IL192950A0/en unknown
-
2009
- 2009-10-15 US US12/580,112 patent/US8093355B2/en active Active