BRPI0813262A2 - Biomarcadores de destruição de articulação para terapia de doença inflamatória de articulação anti-il-17a - Google Patents
Biomarcadores de destruição de articulação para terapia de doença inflamatória de articulação anti-il-17aInfo
- Publication number
- BRPI0813262A2 BRPI0813262A2 BRPI0813262A BRPI0813262A2 BR PI0813262 A2 BRPI0813262 A2 BR PI0813262A2 BR PI0813262 A BRPI0813262 A BR PI0813262A BR PI0813262 A2 BRPI0813262 A2 BR PI0813262A2
- Authority
- BR
- Brazil
- Prior art keywords
- joint
- biomarkers
- disease therapy
- inflammatory
- destruction
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Rheumatology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Rehabilitation Therapy (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US94523907P | 2007-06-20 | 2007-06-20 | |
PCT/US2008/007770 WO2008156865A2 (en) | 2007-06-20 | 2008-06-20 | Joint destruction biomarkers for anti-il-17a therapy of inflammatory joint disease |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0813262A2 true BRPI0813262A2 (pt) | 2015-04-14 |
Family
ID=39858472
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0813262 BRPI0813262A2 (pt) | 2007-06-20 | 2008-06-20 | Biomarcadores de destruição de articulação para terapia de doença inflamatória de articulação anti-il-17a |
Country Status (9)
Country | Link |
---|---|
US (1) | US20100239590A1 (pt) |
EP (1) | EP2171449A2 (pt) |
JP (1) | JP5237366B2 (pt) |
CN (1) | CN101932935A (pt) |
AU (1) | AU2008266745B2 (pt) |
BR (1) | BRPI0813262A2 (pt) |
CA (1) | CA2690568A1 (pt) |
CO (1) | CO6351824A2 (pt) |
WO (1) | WO2008156865A2 (pt) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2288382B1 (en) | 2008-05-05 | 2018-08-29 | NovImmune SA | Anti- il-17a/il-17f cross-reactive antibodies and methods of use thereof |
EP2384367A4 (en) * | 2008-12-30 | 2013-07-10 | Janssen Biotech Inc | SERUM MARKERS TO PREDICT THE CLINICAL RESPONSE TO ANTI-TNF ANTIBODIES IN PATIENTS WITH MORBUS BECHTEREW |
AU2011233753A1 (en) * | 2010-03-31 | 2012-09-13 | Anamar Ab | Method to detect tissue degradation leading to inflammation |
CA2813849C (en) * | 2010-11-05 | 2021-06-15 | Novartis Ag | Secukinumab for use in the treatment of ankylosing spondylitis |
CA2856252A1 (en) * | 2011-11-21 | 2013-05-30 | Novartis Ag | Methods of treating psoriatic arthritis (psa) using il-17 antagonists and psa response or non-response alleles |
US9284283B2 (en) | 2012-02-02 | 2016-03-15 | Ensemble Therapeutics Corporation | Macrocyclic compounds for modulating IL-17 |
WO2014208645A1 (ja) * | 2013-06-28 | 2014-12-31 | 中外製薬株式会社 | そう痒を伴う疾患に罹患した患者のil-31アンタゴニストによる治療に対する応答を予測する方法 |
WO2015009754A2 (en) | 2013-07-15 | 2015-01-22 | Svoboda Steven J | Methods and apparatus for assessment of risk for joint injury |
WO2015048842A1 (en) * | 2013-10-04 | 2015-04-09 | Cell Ideas Pty Ltd | Biomarkers for cell therapy |
WO2015132241A1 (en) * | 2014-03-03 | 2015-09-11 | Novo Nordisk A/S | Treatment of inflammatory diseases |
US20160125142A1 (en) * | 2014-11-05 | 2016-05-05 | Omar Awad | Interactive Electronic Health Record System for Retrieving, Reviewing, and Updating Health Records at the Point of Care |
AU2020237509A1 (en) * | 2019-03-12 | 2021-08-05 | Novus International Inc. | Biomarkers for joint ailments and uses thereof |
US20220340660A1 (en) * | 2019-10-01 | 2022-10-27 | Merck Sharp & Dohme Corp. | Biomarkers for anti-tigit antibody treatment |
CN114518416B (zh) * | 2020-11-20 | 2024-05-24 | 上海交通大学医学院附属瑞金医院 | 一种判断银屑病对il-17a抗体应答反应及其复发的标志物 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5300434A (en) * | 1987-11-06 | 1994-04-05 | Washington Research Foundation | Hybridoma cell line producing an antibody to type-I collagen amino-terminal telopeptide |
DE69727582T2 (de) * | 1996-08-15 | 2004-12-23 | Novartis Ag | Test zur quantifizierung von arthritiszustanden |
DE69738841D1 (de) * | 1996-12-23 | 2008-08-28 | Immunex Corp | Ligand für rezeptor aktivator of nf-kappa b, ligand ist mitglied der tnf superfamilie |
JP2000186046A (ja) * | 1998-10-14 | 2000-07-04 | Snow Brand Milk Prod Co Ltd | 慢性関節リウマチ治療剤及び診断方法 |
US20040171109A1 (en) * | 2000-11-10 | 2004-09-02 | Dominik Haudenschild | IL-17 receptor-like protein, uses thereof, and modulation of catabolic activity of il-17 cytokines on bone and cartilage |
US20040203072A1 (en) * | 2002-11-08 | 2004-10-14 | Barnes-Jewish Hospital | Uncoupled collagen synthesis and degradation assays |
EP2280285A1 (en) * | 2003-09-15 | 2011-02-02 | Oklahoma Medical Research Foundation | Method of using cytokine assays to diagnose, treat, and evaluate inflammatory and autoimmune diseases |
JP2008508858A (ja) * | 2004-05-13 | 2008-03-27 | イムクローン システムズ インコーポレイティド | マクロファージ−刺激タンパク質受容体(ron)の阻害 |
AU2005254998B2 (en) * | 2004-06-10 | 2011-10-27 | Zymogenetics, Inc. | Soluble ZcytoR14, anti-ZcytoR14 antibodies and binding partners and methods of using in inflammation |
GB0417487D0 (en) * | 2004-08-05 | 2004-09-08 | Novartis Ag | Organic compound |
ATE497508T1 (de) * | 2004-10-01 | 2011-02-15 | Max Planck Gesellschaft | Gegen das säugetier-eag1-ionenkanalprotein gerichtete antikörper |
EP1824882B1 (en) * | 2004-12-13 | 2012-02-08 | Cephalon Australia (VIC) Pty Ltd | Osteoprotegerin variant proteins |
CN102178953A (zh) * | 2005-02-14 | 2011-09-14 | 惠氏公司 | 白介素-17f抗体及其它il-17f信号传递拮抗剂和它们的用途 |
DE102005029845B4 (de) * | 2005-06-27 | 2017-03-23 | Orgentec Diagnostika Gmbh | Verfahren zur Diagnose von rheumatischen Erkrankungen |
PL1931697T3 (pl) * | 2005-09-28 | 2011-03-31 | Zymogenetics Inc | Antagoniści interleukiny IL-17A i IL-17F oraz sposoby ich zastosowania |
ES2347840T3 (es) * | 2006-02-10 | 2010-11-04 | Zymogenetics, Inc. | Il-17rcx4 soluble y procedimiento de utilizacion en la inflamacion. |
EP1996622A2 (en) * | 2006-03-10 | 2008-12-03 | Zymogenetics, Inc. | Antibodies that bind both il-17a and il-17f and methods of using the same |
MX2009001620A (es) * | 2006-08-11 | 2009-02-23 | Schering Corp | Anticuerpos para il-17a. |
-
2008
- 2008-06-20 EP EP08768695A patent/EP2171449A2/en not_active Withdrawn
- 2008-06-20 AU AU2008266745A patent/AU2008266745B2/en not_active Ceased
- 2008-06-20 CA CA2690568A patent/CA2690568A1/en not_active Abandoned
- 2008-06-20 JP JP2010513265A patent/JP5237366B2/ja not_active Expired - Fee Related
- 2008-06-20 BR BRPI0813262 patent/BRPI0813262A2/pt not_active IP Right Cessation
- 2008-06-20 WO PCT/US2008/007770 patent/WO2008156865A2/en active Application Filing
- 2008-06-20 CN CN2008801035068A patent/CN101932935A/zh active Pending
- 2008-06-20 US US12/663,381 patent/US20100239590A1/en not_active Abandoned
-
2009
- 2009-12-17 CO CO09144823A patent/CO6351824A2/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU2008266745B2 (en) | 2014-04-17 |
AU2008266745A1 (en) | 2008-12-24 |
US20100239590A1 (en) | 2010-09-23 |
JP5237366B2 (ja) | 2013-07-17 |
CA2690568A1 (en) | 2008-12-24 |
JP2010530972A (ja) | 2010-09-16 |
WO2008156865A3 (en) | 2009-03-12 |
CO6351824A2 (es) | 2011-12-20 |
EP2171449A2 (en) | 2010-04-07 |
WO2008156865A2 (en) | 2008-12-24 |
CN101932935A (zh) | 2010-12-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |